Wound-healing defects in mice lacking fibrinogen

Blood

Volumn 97, Issue 12, 2001, Pages 3691-3698

  Drew, Angela F ^a,b,c   Liu, Hong ^a,b,c   Davidson, Jeffrey M ^a,b,c   Daugherty, Cynthia C ^a,b,c   Degen, Jay L ^a,b,c,d  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; EPITHELIUM CELL; EPITHELIUM HYPERPLASIA; EPITHELIZATION; FIBRINOGEN DEFECT; GRANULATION TISSUE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; TENSILE STRENGTH; TISSUE REPAIR; WOUND HEALING;

EID: 0035878005     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.12.3691     Document Type: Article

References (28)

1. Martin P. Wound healing - aiming for perfect skin regeneration. Science. 1997;276:75-81,
2. , Horsburgh CR Jr, Clark RA, Kirkpatrick CH. Lymphokines and platelets promote human monocyte adherence to fibrinogen and fibronectin in vitro. J Leukoc Biol. 1987;41:14-24.
3. Altieri DC, Plescia J, Plow EF. The structural motif glycine 190-valine 202 of the fibrinogen gamma chain interacts with CD11b/CD18 integrin (alpha M beta 2, Mac-1) and promotes leukocyte adhesion. J Biol Chem. 1993;268:1847-1853.
4. Sahni A, Francis CW. Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation. Blood. 2000;96:3772-3778.
5. Sahni A, Odrljin T, Francis CW. Binding of basic fibroblast growth factor to fibrinogen and fibrin. J Biol Chem. 1998;273:7554-7559.
6. Brown LF, Lanir N, McDonagh J, Tognazzi K, Dvorak AM, Dvorak HF. Fibroblast migration in fibrin gel matrices. Am J Pathol. 1993;142:273-283.
7. Suh TT, Holmback K, Jensen NJ, et al. Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. Genes Dev. 1995;9:2020-2033.
8. Drew AF, Kaufman AH, Kombrinck KW, et al. Ligneous conjunctivitis in plasminogen-deficient mice. Blood. 1998;91:1616-1624,
9. Stegemann H, Stalder K. Determination of hydroxyproline. Clin Chim Acta. 1967;18:267-273.
10. Collawn SS. Occlusion following laser resurfacing promotes reepithelialization and wound healing, Plast Reconstr Surg. 2000;105:2180-2189.
11. , Hayward PG, Robson MC. Animal models of wound contraction. In Barbul A, Caldwell MD, Eaglstein WH, et al, eds. Clinical and experimental approaches to dermal and epidermal repair: normal and chronic wounds. Vol 365. Progress in clinical and biological research. New York, NY: Wiley-Liss; 1991:301-312.
12. Rao CM, Ramesh KV, Bairy KL, Kulkarni DR. A simple method to quantify maturation of wound collagen. Indian J Exp Biol. 1991;29:156-158.
13. Ni H, Denis CV, Subbarao S, et al, Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest. 2000;106:385-392.
14. Woodley DT, Bachmann PM, O'Keefe EJ. The role of matrix components in human keratinocyte re-epithelialization. In Barbul A, Caldwell MD, Eaglstein WH, et al eds. Clinical and experimental approaches to dermal and epidermal repair: normal and chronic wounds. Vol 365. Progress in clinical and biological research. New York, NY: Wiley-Liss; 1991:129-140.
15. Romer J, Bugge TH, Pyke C, et al. Impaired wound healing in mice with a disrupted plasminogen gene. Nat Med. 1996;2:287-292.
16. Bugge TH, Kombrinck KW, Flick MJ, Daugherty CC, Danton MJ, Degen JL. Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency. Cell, 1996;87:709-719.
17. Dvorak HF, Harvey VS, Estrella P, Brown LF, McDonagh J, Dvorak AM. Fibrin containing gels induce angiogenesis: implications for tumor stroma generation and wound healing. Lab Invest. 1987;57:673-686.
18. Thompson WD, Smith EB, Stirk CM, Stout AJ, Kochhar A. Factors relevant to stimulatory activity of fibrin degradation products in vivo. Blood Coagul Fibrinolysis. 1990;1:517-520.
19. Thompson WD, Smith EB, Stirk CM, Marshall FI, Stout AJ, Kocchar A. Angiogenic activity of fibrin degradation products is located in fibrin fragment E. J Pathol. 1992;168:47-53.
20. Clark RA. Fibronectin matrix deposition and fibronectin receptor expression in healing and normal skin. J Invest Dermatol. 1990;94(suppl 6):128-134.
21. Singer II, Kawka DW, Kazazis DM, Clark RA. In vivo co-distribution of fibronectin and actin fibers in granulation tissue: immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface. J Cell Biol. 1984;98:2091-2106.
22. Reed MJ, Puolakkainen P, Lane TF, Dickerson D, Bornstein P, Sage EH. Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J Histochem Cytochem. 1993;41:1467-1477.
23. Gailit J, Clark RA. Wound repair in the context of extracellular matrix. Curr Opin Cell Biol. 1994;6:717-725.
24. Mochitate K, Pawelek P, Grinnell F. Stress relaxation of contracted collagen gels: disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis. Exp Cell Res. 1991;193:198-207.
25. Pardes JB, Takagi H, Martin TA, Ochoa MS, Falanga V. Decreased levels of alpha 1(I) procollagen mRNA in dermal fibroblasts grown on fibrin gels and in response to fibrinopeptide B. J Cell Physiol. 1995;162:9-14.
26. Palumbo JS, Kombrinck KW, Drew AF, et al. Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells, Blood. 2000;96:3302-3309.
27. Busso N, Peclat V, Van Ness K, et al. Exacerbation of antigen-induced arthritis in urokinase-deficient mice. J Clin Invest. 1998;102:41-50.
28. Lou XJ, Boonmark NW, Horrigan FT, Degen JL, Lawn RM. Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice, Proc Natl Acad Sci U S A. 1998;95:12591-12595.