A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 16, 1998, Pages 9524-9529

  Denis, Cécile ^a   Methia, Nassia ^a   Frenette, Paul S ^a   Rayburn, Helen ^c   Ullman Culleré, Mollie ^c   Hynes, Richard O ^b,c   Wagner, Denisa D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VON WILLEBRAND FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BLOOD VESSEL INJURY; GENE TARGETING; HEMOSTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOSIS; VON WILLEBRAND DISEASE;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HEMOSTASIS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PHENOTYPE; THROMBOSIS; VON WILLEBRAND DISEASE; VON WILLEBRAND FACTOR;

ANIMALIA;

EID: 0032483024     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.16.9524     Document Type: Article

References (26)

1. Ewenstein, B. M. (1997) Annu. Rev. Med. 48, 525-542.
2. Andrews, R. K., Lopez, J. A. & Berndt, M. C. (1997) Int. J. Biochem. Cell Biol. 29, 91-105.
3. Weiss, H. J., Sussman, I. I. & Hoyer, L. W. (1977) J. Clin. Invest. 60, 390-404.
4. Bowie, E. J. & Owen, C. A. (1989) in Coagulation and Bleeding Disorders, eds. Zimmerman, T. S. & Ruggeri, Z. M. (Dekker, New York), pp. 305-324.
5. Wu, Q. Y., Drouet, L., Carrier, J. L., Rothchild, C., Berard, M., Rouault, C., Caen, J.-P. & Meyer, D. (1987) Arteriosclerosis 7, 47-54.
6. Nichols, T. C., Bellinger, D. A., Davis, K. E., Koch, G. G., Reddick, R. L., Read, M. S., Rapacz, J., Hasler-Rapacz, J., Brinkhous, K. & Griggs, T. R. (1992) Am. J. Pathol. 140, 403-415.
7. Sakariassen, P. G., Arts, P. A. M. M., de Groot, P. G., Houjdlik, W. P. M. & Sixma, J. J. (1983) J. Lab. Clin. Med. 102, 522-535.
8. Ruggeri, Z. M. (1997) Thromb. Haemostasis 78, 611-616.
9. Mayadas, T. N., Johnson, R. C., Rayburn, H., Hynes, R. O. & Wagner, D. D. (1993) Cell 74, 541-554.
10. Bradley, A. (1987) in Teratocarcinoma and Embryonic Stem Cells: A Practical Approach, ed. Robertson, E. J. (IRL, Oxford), pp. 113-151.
11. Nichols, W. C., Cooney, K. A., Mohlke, K. L., Ballew, J. D., Yang, A., Bruck, M. E., Reddington, M., Novak, E. K., Swank, R. T. & Ginsburg, D. (1994) Blood 83, 3225-3231.
12. Subramaniam, M., Frenette, P. S., Saffaripour, S., Johnson, R. C, Hynes, R. O. & Wagner, D. D. (1996) Blood 87, 1238-1242.
13. Baker, M. & Wayland, H. (1974) Microvasc. Res. 7, 131-143.
14. Journet, A. M., Saffaripour, S. & Wagner, D. D. (1993) Thromb. Haemostasis 70, 1053-1057.
15. Zuccarello, M. & Anderson, D. K. (1989) Stroke (Dallas) 20, 367-371.
16. Wei, X-Q., Charles, I. G., Smith, A., Ure, J., Feng, G.-J., Huang, F.-P., Xu, D., Muller, W., Moncada, S. & Liew, F. Y. (1995) Nature (London) 375, 408-411.
17. Georges-Labouesse, E. N., George, E. L., Rayburn, H. & Hynes, R. O. (1996) Dev. Dyn. 207, 145-156.
18. Bi, L., Lawler, A. M., Antonarakis, S.E., High, K. A., Gearhart, J. D. & Kazazian, H. H., Jr. (1995) Nat. Genet. 10, 119-121.
19. Bi, L., Sarkar, R., Naas, T., Lawler, A. M., Pain, J., Shumaker, S. L., Bedian V. & Kazazian, H. H., Jr. (1996) Blood 88, 3446-3450.
20. Wang, L., Zoppè, M., Hackeng, T. M., Griffin, J. H., Lee, K.-F. & Verma, I. M. (1997) Proc. Natl. Acad. Sci. USA 94, 11563-11566.
21. Suh, T. T., Holmbäck, K., Jensen, N. J., Daugherty, C. C., Small, K., Simon, D. I., Potter, S. S. & Degen, J. L. (1995) Genes Dev. 9, 2020-2033.
22. Holmbäck, K., Danton, M. J. S., Suh, T. T., Daugherty C. C. & Degen, J. L. (1996) EMBO J. 15, 5760-5771.
23. Lollar, P., Hills-Eubanks, D. C. & Parker, C. G. (1988) J. Biol. Chem. 263, 10451-10455.
24. Hoyer, L. W. (1981) Blood 58, 1-13.
25. Holmberg, L. & Nilsson, I. M. (1992) Eur. J. Haematol. 48, 127-141.
26. Nierodzik, M. L., Klepfish, A. & Karpatkin, S. (1995) Thromb. Haemostasis 74, 282-290.