HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability

Nature Cell Biology

Volumn 9, Issue 4, 2007, Pages 391-401

  Collis, Spencer J ^a   Barber, Louise J ^a   Clark, Allison J ^a   Martin, Julie S ^a   Ward, Jordan D ^a   Boulton, Simon J ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; ATRIP PROTEIN; CELL PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CLASPIN; CLK 2 PROTEIN; DNA; FANCONI ANEMIA GROUP D2 PROTEIN; PROTEASOME; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; RAD51 PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL RHYTHM; CAENORHABDITIS ELEGANS; CELL CYCLE S PHASE; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; FANCONI ANEMIA; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RADIOSENSITIVITY; SEQUENCE HOMOLOGY; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BLOTTING, WESTERN; CDC25 PHOSPHATASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; EXODEOXYRIBONUCLEASES; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MODELS, BIOLOGICAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; S PHASE; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 34047115860     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1555     Document Type: Article

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