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Volumn 13, Issue 4, 2007, Pages 415-429

Pharmaceutical and biomedical potential of PEGylated dendrimers

Author keywords

Cytotoxity; Dendrimer; Drug delivery; Gene delivery; MRI contrast agents; PEGylation; Solubilization; Targeting

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; ARTEMETHER; BETAMETHASONE DERIVATIVE; BETAMETHASONE DIPROPIONATE; BETAMETHASONE VALERATE; CITRIC ACID; CONTRAST MEDIUM; DENDRIMER; DICLOFENAC; DOXORUBICIN; FLUOROURACIL; INDOMETACIN; LIPOSOME; LYSINE; MACROGOL; MEFENAMIC ACID; MESALAZINE; MESYLIC ACID; METHOTREXATE; NANOCARRIER; PACLITAXEL; PENICILLIN V; PLASMID DNA; POLYAMIDOAMINE; POLYESTER; PYRENE; PYRIDINE; RIFAMPICIN; UNINDEXED DRUG;

EID: 33947596482     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161207780162999     Document Type: Review
Times cited : (126)

References (144)
  • 1
    • 0043063880 scopus 로고    scopus 로고
    • Dendrimers: A new class of nanoscopic containers and delivery devices
    • Aulenta F, Hayes W, Rannard S. Dendrimers: a new class of nanoscopic containers and delivery devices. Eur Polym J 2003; 39: 1741-71.
    • (2003) Eur Polym J , vol.39 , pp. 1741-1771
    • Aulenta, F.1    Hayes, W.2    Rannard, S.3
  • 2
    • 0037091001 scopus 로고    scopus 로고
    • Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy
    • Stiriba SE, Frey H, Haag R. Dendritic polymers in biomedical applications: from potential to clinical use in diagnostics and therapy. Angew Chem Int Ed Engl 2002; 41: 1329-34.
    • (2002) Angew Chem Int Ed Engl , vol.41 , pp. 1329-1334
    • Stiriba, S.E.1    Frey, H.2    Haag, R.3
  • 4
    • 1642414039 scopus 로고    scopus 로고
    • Dendrimers in drug research
    • Boas U, Heegaard PMH. Dendrimers in drug research. Chem Soc Rev 2004; 33: 43-63.
    • (2004) Chem Soc Rev , vol.33 , pp. 43-63
    • Boas, U.1    Heegaard, P.M.H.2
  • 5
    • 0025373701 scopus 로고
    • Starburst Dendrimers: Molecular-Level Control of Size, Shape, Surface Chemistry, Topology, and Flexibility from Atoms to Macroscopic Matter
    • Tomalia DA, Naylor AM, Goddard WA III. Starburst Dendrimers: Molecular-Level Control of Size, Shape, Surface Chemistry, Topology, and Flexibility from Atoms to Macroscopic Matter. Angew Chem Int Ed Engl 1990; 29: 138-75.
    • (1990) Angew Chem Int Ed Engl , vol.29 , pp. 138-175
    • Tomalia, D.A.1    Naylor, A.M.2    Goddard III, W.A.3
  • 8
    • 0038817081 scopus 로고
    • Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
    • Hawker CJ, Frechet JMJ. Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules. J Am Chem Soc 1990; 112: 7638-47.
    • (1990) J Am Chem Soc , vol.112 , pp. 7638-7647
    • Hawker, C.J.1    Frechet, J.M.J.2
  • 9
    • 0033997598 scopus 로고    scopus 로고
    • Water-soluble unimolecular micelles: Their potential as drug delivery agents
    • Liu M, Kono K, Frechet JMJ. Water-soluble unimolecular micelles: their potential as drug delivery agents. J Control Release 2000; 65: 121-31.
    • (2000) J Control Release , vol.65 , pp. 121-131
    • Liu, M.1    Kono, K.2    Frechet, J.M.J.3
  • 10
    • 0032637389 scopus 로고    scopus 로고
    • Water-soluble dendrimer-polyethylene glycol starlike conjugates as potential drug carriers
    • Liu M, Kono K, Frechet JMJ. Water-soluble dendrimer-polyethylene glycol starlike conjugates as potential drug carriers. J Polym Sci A 1999; 37: 3492-503.
    • (1999) J Polym Sci A , vol.37 , pp. 3492-3503
    • Liu, M.1    Kono, K.2    Frechet, J.M.J.3
  • 13
    • 0029360545 scopus 로고
    • Chemistry of polyethylene glycol conjugates with biologically active molecules
    • Zalipsky S. Chemistry of polyethylene glycol conjugates with biologically active molecules. Adv Drug Del Rev 1995; 16: 157-82.
    • (1995) Adv Drug Del Rev , vol.16 , pp. 157-182
    • Zalipsky, S.1
  • 15
    • 0037433811 scopus 로고    scopus 로고
    • A PEGylated dendritic nanaparticulate carrier of fluorouracil
    • Bhadra D, Bhadra S, Jain S, Jain NK. A PEGylated dendritic nanaparticulate carrier of fluorouracil. Int J Pharm 2003; 257: 111-24.
    • (2003) Int J Pharm , vol.257 , pp. 111-124
    • Bhadra, D.1    Bhadra, S.2    Jain, S.3    Jain, N.K.4
  • 16
    • 0037183605 scopus 로고    scopus 로고
    • Synthesis, characterization, and biocompatibility of polyethylenimine-graftpoly(ethylene glycol) block copolymers
    • Petersen H, Fechner PM, Fischer D, Kissel T. Synthesis, characterization, and biocompatibility of polyethylenimine-graftpoly(ethylene glycol) block copolymers. Macromolecules 2002; 35: 6867-74.
    • (2002) Macromolecules , vol.35 , pp. 6867-6874
    • Petersen, H.1    Fechner, P.M.2    Fischer, D.3    Kissel, T.4
  • 17
    • 4644258898 scopus 로고    scopus 로고
    • Dendrimers of citric acid and poly (ethylene glycol) as the new drug-delivery agents
    • Namazi H, Adeli M. Dendrimers of citric acid and poly (ethylene glycol) as the new drug-delivery agents. Biomaterials 2005; 26: 1175-83.
    • (2005) Biomaterials , vol.26 , pp. 1175-1183
    • Namazi, H.1    Adeli, M.2
  • 18
    • 0346735304 scopus 로고    scopus 로고
    • Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier
    • Tansey W, Ke S, Cao X-Y, Marites J. Pasuelo, Wallace S, Li C. Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier. J Control Release 2004; 94: 39-51.
    • (2004) J Control Release , vol.94 , pp. 39-51
    • Tansey, W.1    Ke, S.2    Cao, X.-Y.3    Marites, J.4    Pasuelo5    Wallace, S.6    Li, C.7
  • 19
    • 0035478289 scopus 로고    scopus 로고
    • Solubilization and release properties of PEGylated diaminobutane poly(propylene imine) dendrimers
    • Sideratou Z, Tsiourvas D, Paleos CM. Solubilization and release properties of PEGylated diaminobutane poly(propylene imine) dendrimers. J Colloid Int Sci 2001; 242: 272-6.
    • (2001) J Colloid Int Sci , vol.242 , pp. 272-276
    • Sideratou, Z.1    Tsiourvas, D.2    Paleos, C.M.3
  • 20
    • 0033657796 scopus 로고    scopus 로고
    • Synthesis of Poly amidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs
    • Kojima C, Kono K, Maruyama K, Takagishi T. Synthesis of Poly amidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconj Chem 2000; 11: 910-7.
    • (2000) Bioconj Chem , vol.11 , pp. 910-917
    • Kojima, C.1    Kono, K.2    Maruyama, K.3    Takagishi, T.4
  • 21
    • 0037130553 scopus 로고    scopus 로고
    • Structure-activity relationships of Poly(L-lysine): Effects of PEGylation and molecular shape on physiochemical and biological properties in gene delivery
    • Mannisto M, Vanderkerken S, Toncheve V, Elomaa M, Ruponen, Schacht E, et al. Structure-activity relationships of Poly(L-lysine): effects of PEGylation and molecular shape on physiochemical and biological properties in gene delivery. J Control Release 2002; 83:169-82.
    • (2002) J Control Release , vol.83 , pp. 169-182
    • Mannisto, M.1    Vanderkerken, S.2    Toncheve, V.3    Elomaa, M.4    Ruponen5    Schacht, E.6
  • 22
    • 33645505167 scopus 로고    scopus 로고
    • Dendrimers: Novel polymeric nanoarchitecture for solubility enhancement
    • Gupta U, Agashe HB, Asthana A, Jain NK. Dendrimers: novel polymeric nanoarchitecture for solubility enhancement. Biomacromolecules 2006; 7: 649-58.
    • (2006) Biomacromolecules , vol.7 , pp. 649-658
    • Gupta, U.1    Agashe, H.B.2    Asthana, A.3    Jain, N.K.4
  • 23
  • 24
    • 0037203696 scopus 로고    scopus 로고
    • Effect of dendrimer on entrapment and release of bioactive from liposomes
    • Khopade AJ, Caruso F, Tripathi P, Nagaich S, Jain NK. Effect of dendrimer on entrapment and release of bioactive from liposomes. Int J Pharm 2002; 232: 157-62.
    • (2002) Int J Pharm , vol.232 , pp. 157-162
    • Khopade, A.J.1    Caruso, F.2    Tripathi, P.3    Nagaich, S.4    Jain, N.K.5
  • 25
    • 28744445460 scopus 로고    scopus 로고
    • Dendrimer biocompatibility and toxicity
    • Duncan R, Izzo L. Dendrimer biocompatibility and toxicity. Adv Drug Del Rev 2005; 57: 2214-37.
    • (2005) Adv Drug Del Rev , vol.57 , pp. 2214-2237
    • Duncan, R.1    Izzo, L.2
  • 26
    • 0036183962 scopus 로고    scopus 로고
    • Dendritic polyglycerol: A new versatile biocompatible material
    • Frey H, Haag R. Dendritic polyglycerol: a new versatile biocompatible material. Rev Mole Biotech 2002; 90: 257-67.
    • (2002) Rev Mole Biotech , vol.90 , pp. 257-267
    • Frey, H.1    Haag, R.2
  • 27
    • 28744437107 scopus 로고    scopus 로고
    • Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex
    • Patri AK, Kukowska-Lotallo JF, Baker JR Jr. Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. Adv Drug Del Rev 2005; 57: 2203-14.
    • (2005) Adv Drug Del Rev , vol.57 , pp. 2203-2214
    • Patri, A.K.1    Kukowska-Lotallo, J.F.2    Baker Jr., J.R.3
  • 28
    • 28744443398 scopus 로고    scopus 로고
    • Dendrimers in biomedical applications-reflection on the field
    • Svenson S, Tomalia DA. Dendrimers in biomedical applications-reflection on the field. Ad Drug Deli Rev 2005; 57: 2106-29.
    • (2005) Ad Drug Deli Rev , vol.57 , pp. 2106-2129
    • Svenson, S.1    Tomalia, D.A.2
  • 29
    • 12844258906 scopus 로고    scopus 로고
    • Dendrimers and dendritic polymers in drug delivery
    • Gillies ER, Frechet JMJ. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 2005; 10: 35-43.
    • (2005) Drug Discov Today , vol.10 , pp. 35-43
    • Gillies, E.R.1    Frechet, J.M.J.2
  • 30
    • 0036183447 scopus 로고    scopus 로고
    • Gene transfer into eukaryotic cells using activated polyamidoamine dendrimers
    • Dennig J, Duncan E. Gene transfer into eukaryotic cells using activated polyamidoamine dendrimers. Rev Mole Biotech 2002; 90: 339-47.
    • (2002) Rev Mole Biotech , vol.90 , pp. 339-347
    • Dennig, J.1    Duncan, E.2
  • 32
    • 33746401466 scopus 로고    scopus 로고
    • Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration
    • Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M. Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. J Control Release 2006; 114: 69-77.
    • (2006) J Control Release , vol.114 , pp. 69-77
    • Okuda, T.1    Kawakami, S.2    Maeie, T.3    Niidome, T.4    Yamashita, F.5    Hashida, M.6
  • 33
    • 0041940695 scopus 로고    scopus 로고
    • Gadolinium(III) D03A macrocycles and polyethylene glycol coupled to dendrimers, Effect of molecular weight on physical and biological properties of macromolecular magnetic resonance imaging contrast agents
    • Margerum LD, Campion BK, Koo M, Shargill N, Lai JJ, Marumoto A, et al. Gadolinium(III) D03A macrocycles and polyethylene glycol coupled to dendrimers, Effect of molecular weight on physical and biological properties of macromolecular magnetic resonance imaging contrast agents. J Alloys Compd 1997; 249: 185-90.
    • (1997) J Alloys Compd , vol.249 , pp. 185-190
    • Margerum, L.D.1    Campion, B.K.2    Koo, M.3    Shargill, N.4    Lai, J.J.5    Marumoto, A.6
  • 35
    • 13444303906 scopus 로고    scopus 로고
    • PEGylated peptide-based dendritic nanoparticulate systems for delivery of artemether
    • Bhadra D, Bhadra S, Jain NK. PEGylated peptide-based dendritic nanoparticulate systems for delivery of artemether. J Drug Del Sci Tech 2005; 15: 65-73
    • (2005) J Drug Del Sci Tech , vol.15 , pp. 65-73
    • Bhadra, D.1    Bhadra, S.2    Jain, N.K.3
  • 36
    • 31544460355 scopus 로고    scopus 로고
    • Novel Monodisperse PEG-Dendrons as New Tools for Targeted Drug Delivery: Synthesis, Characterization and Cellular Uptake
    • Berna M, Dalzoppo D, Pasut G, Manunta M, Izzo L, Jones AT, et al. Novel Monodisperse PEG-Dendrons as New Tools for Targeted Drug Delivery: Synthesis, Characterization and Cellular Uptake. Biomacromolecules 2006; 7: 146-53.
    • (2006) Biomacromolecules , vol.7 , pp. 146-153
    • Berna, M.1    Dalzoppo, D.2    Pasut, G.3    Manunta, M.4    Izzo, L.5    Jones, A.T.6
  • 37
    • 0242662544 scopus 로고    scopus 로고
    • Effects of ethylene glycol-based graft, starshaped, and dendritic polymers on solubilization and controlled release of paclitaxel
    • Ooya T, Lee J, Park K. Effects of ethylene glycol-based graft, starshaped, and dendritic polymers on solubilization and controlled release of paclitaxel. J Control Release 2003; 93: 121-7.
    • (2003) J Control Release , vol.93 , pp. 121-127
    • Ooya, T.1    Lee, J.2    Park, K.3
  • 38
    • 0029953311 scopus 로고    scopus 로고
    • Stimuli-Responsive Hybrid Macromolecules: Novel Amphiphilic Star Copolymers with Dendritic Groups at the Periphery
    • Gitsov I, Frechet JMJ, Stimuli-Responsive Hybrid Macromolecules: Novel Amphiphilic Star Copolymers with Dendritic Groups at the Periphery. J Am Chem Soc 1996; 118: 3785-6.
    • (1996) J Am Chem Soc , vol.118 , pp. 3785-3786
    • Gitsov, I.1    Frechet, J.M.J.2
  • 39
    • 0242269078 scopus 로고    scopus 로고
    • Penicillin V-conjugated PEG-PAMAM star polymers
    • Yang Hu, Lopina ST. Penicillin V-conjugated PEG-PAMAM star polymers. J Biomater Sci Polymer Edn 2003; 14: 1043-56.
    • (2003) J Biomater Sci Polymer Edn , vol.14 , pp. 1043-1056
    • Yang, Hu.1    Lopina, S.T.2
  • 41
    • 11844261529 scopus 로고    scopus 로고
    • Preparation and characterization of poly(amidoamine) dendrimers functionalized with a rhenium carbonyl complex and PEG as new IR probes for carbonyl metallo immunoassay
    • Heldt JM, Durand NF, Salmain M, Vessieres A, Jaouen G, Preparation and characterization of poly(amidoamine) dendrimers functionalized with a rhenium carbonyl complex and PEG as new IR probes for carbonyl metallo immunoassay. J Organometallic Chem 2004; 689: 4775-82.
    • (2004) J Organometallic Chem , vol.689 , pp. 4775-4782
    • Heldt, J.M.1    Durand, N.F.2    Salmain, M.3    Vessieres, A.4    Jaouen, G.5
  • 42
    • 0030042315 scopus 로고    scopus 로고
    • Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers
    • Roberts JC, Bhalgat MK, Zera RT. Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers. J Biomed Mater Res 1996; 30: 53-65.
    • (1996) J Biomed Mater Res , vol.30 , pp. 53-65
    • Roberts, J.C.1    Bhalgat, M.K.2    Zera, R.T.3
  • 43
    • 4043103282 scopus 로고    scopus 로고
    • Cytotoxicity, haemolysis, and acute in vivo toxicity of dendrimer based on melamine, candidate vehicles for drug delivery
    • Chen HT, Neerman MF, Parrish AR, Simanek E. Cytotoxicity, haemolysis, and acute in vivo toxicity of dendrimer based on melamine, candidate vehicles for drug delivery. J Am Chem Soc 2004; 126: 10044-8.
    • (2004) J Am Chem Soc , vol.126 , pp. 10044-10048
    • Chen, H.T.1    Neerman, M.F.2    Parrish, A.R.3    Simanek, E.4
  • 44
    • 0035997509 scopus 로고    scopus 로고
    • The lower generation polypropyleneimine dendrimers are effective gene transfer agents
    • Zinselmeyer BH, Mackay SP, Schatzlein AG, Uchegbu IF. The lower generation polypropyleneimine dendrimers are effective gene transfer agents. Pharma Res 2002; 19: 960-7.
    • (2002) Pharma Res , vol.19 , pp. 960-967
    • Zinselmeyer, B.H.1    Mackay, S.P.2    Schatzlein, A.G.3    Uchegbu, I.F.4
  • 45
  • 46
    • 33744489905 scopus 로고    scopus 로고
    • Polystyrene-graft-polyglycerol resins: A new type of high-loading hybrid support for organic synthesis
    • Roller S, Turk H, Stumbe JF, Rapp W, Haag R. Polystyrene-graft-polyglycerol resins: a new type of high-loading hybrid support for organic synthesis. J Comb Chem 2006; 8: 350-4.
    • (2006) J Comb Chem , vol.8 , pp. 350-354
    • Roller, S.1    Turk, H.2    Stumbe, J.F.3    Rapp, W.4    Haag, R.5
  • 47
    • 3042628701 scopus 로고    scopus 로고
    • Self-assembled monolayers of dendritic polyglycerol derivatives on gold that resist the adsorption of proteins
    • Siegers C, Biesalski M, Haag R. Self-assembled monolayers of dendritic polyglycerol derivatives on gold that resist the adsorption of proteins. Chemistry 2004; 10: 2831-8.
    • (2004) Chemistry , vol.10 , pp. 2831-2838
    • Siegers, C.1    Biesalski, M.2    Haag, R.3
  • 48
    • 0842306880 scopus 로고    scopus 로고
    • Dendritic sulfates as new heparin analogues and potent inhibitors of the complement system
    • Turk H, Haag R, Alban S. Dendritic sulfates as new heparin analogues and potent inhibitors of the complement system. Bioconjug Chem 2004; 15: 162-7.
    • (2004) Bioconjug Chem , vol.15 , pp. 162-167
    • Turk, H.1    Haag, R.2    Alban, S.3
  • 49
    • 32644445013 scopus 로고    scopus 로고
    • Electrolysis as an efficient key step in the homogeneous polymer-supported synthesis of Nsubstituted pyrroles
    • Nad S, Roller S, Haag R, Breinbauer R. Electrolysis as an efficient key step in the homogeneous polymer-supported synthesis of Nsubstituted pyrroles. Org Lett 2006; 8: 403-6.
    • (2006) Org Lett , vol.8 , pp. 403-406
    • Nad, S.1    Roller, S.2    Haag, R.3    Breinbauer, R.4
  • 50
    • 15444367615 scopus 로고    scopus 로고
    • Highly regioselective synthesis of amino-functionalized dendritic polyglycerols by a one-pot hydroformylation/reductive amination sequence
    • Koc F, Wyszogrodzka M, Eilbracht P, Haag R. Highly regioselective synthesis of amino-functionalized dendritic polyglycerols by a one-pot hydroformylation/reductive amination sequence. J Org Chem 2005; 70: 2021-5.
    • (2005) J Org Chem , vol.70 , pp. 2021-2025
    • Koc, F.1    Wyszogrodzka, M.2    Eilbracht, P.3    Haag, R.4
  • 51
    • 28344435624 scopus 로고    scopus 로고
    • High-loading polyglycerol supported reagents for Mitsunobu- and acylation-reactions and other useful polyglycerol derivatives
    • Roller S, Zhou H, Haag R. High-loading polyglycerol supported reagents for Mitsunobu- and acylation-reactions and other useful polyglycerol derivatives. Mol Divers 2005; 9: 305-16.
    • (2005) Mol Divers , vol.9 , pp. 305-316
    • Roller, S.1    Zhou, H.2    Haag, R.3
  • 52
    • 1542341274 scopus 로고
    • Unimolecular micelles and globular amphiphiles dendritic macromolecules as novel recyclable solubilization agents
    • Hawker CJ, Wooley KL, Frechet JMJ. Unimolecular micelles and globular amphiphiles dendritic macromolecules as novel recyclable solubilization agents. J Chem Soc Perkin Trans 1993; 1: 1287-97.
    • (1993) J Chem Soc Perkin Trans , vol.1 , pp. 1287-1297
    • Hawker, C.J.1    Wooley, K.L.2    Frechet, J.M.J.3
  • 53
    • 0038296218 scopus 로고    scopus 로고
    • Dendrimers as potential drug carrier, encapsulation of acidic hydrophobies within water soluble PAMAM derivatives
    • Beezer AE, King ASH, Martin IK, Mitchel JC, Twyman LJ, Wain CF. Dendrimers as potential drug carrier, encapsulation of acidic hydrophobies within water soluble PAMAM derivatives. Tetrahedron Lett 2003; 59: 3873-80.
    • (2003) Tetrahedron Lett , vol.59 , pp. 3873-3880
    • Beezer, A.E.1    King, A.S.H.2    Martin, I.K.3    Mitchel, J.C.4    Twyman, L.J.5    Wain, C.F.6
  • 54
    • 5344265361 scopus 로고    scopus 로고
    • The effect of PAMAM dendrimer generation size and surface functional group on the aqueous solubility of nifedipine
    • Devarakonda B, Hill RA, DeVilliers MM. The effect of PAMAM dendrimer generation size and surface functional group on the aqueous solubility of nifedipine. Int J Pharm 2004; 284: 133-40
    • (2004) Int J Pharm , vol.284 , pp. 133-140
    • Devarakonda, B.1    Hill, R.A.2    DeVilliers, M.M.3
  • 55
    • 27744579521 scopus 로고    scopus 로고
    • Poly(amidoamine) (PAMAM) Dendritic Nanostructures for Controlled Sitespecific Delivery of Acidic Anti-inflammatory Active Ingredient
    • Asthana A, Chauhan AS, Diwan PV, Jain NK. Poly(amidoamine) (PAMAM) Dendritic Nanostructures for Controlled Sitespecific Delivery of Acidic Anti-inflammatory Active Ingredient. AAPS PharmSciTech 2005; 6: 536-42.
    • (2005) AAPS PharmSciTech , vol.6 , pp. 536-542
    • Asthana, A.1    Chauhan, A.S.2    Diwan, P.V.3    Jain, N.K.4
  • 56
    • 33845378981 scopus 로고
    • Micelles. Part 1, Cascade molecules, a new approach to micelles, A (27)-arborol
    • Newkome GR, Yao Z, Baker GR, Gupta VK. Micelles. Part 1, Cascade molecules, a new approach to micelles, A (27)-arborol. J Org Chem 1985; 50: 2003-4.
    • (1985) J Org Chem , vol.50 , pp. 2003-2004
    • Newkome, G.R.1    Yao, Z.2    Baker, G.R.3    Gupta, V.K.4
  • 57
    • 0033734298 scopus 로고    scopus 로고
    • Amphiphilic Dendrimers with Both Octyl and Triethylenoxy Methyl Ether Chain Ends
    • Pan Y, Ford WT. Amphiphilic Dendrimers with Both Octyl and Triethylenoxy Methyl Ether Chain Ends. Macromolecules 2000; 33: 3731-38.
    • (2000) Macromolecules , vol.33 , pp. 3731-3738
    • Pan, Y.1    Ford, W.T.2
  • 59
    • 1642502287 scopus 로고    scopus 로고
    • Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water
    • Yang H, Morris JJ, Lopina ST. Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water. J Colloid Int Sci 2004; 273: 148-54.
    • (2004) J Colloid Int Sci , vol.273 , pp. 148-154
    • Yang, H.1    Morris, J.J.2    Lopina, S.T.3
  • 61
    • 0027655718 scopus 로고
    • Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
    • Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem 1993; 4: 372-9.
    • (1993) Bioconjugate Chem , vol.4 , pp. 372-379
    • Haensler, J.1    Szoka, F.C.2
  • 62
    • 0037161405 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-Conjugated PAMAM Dendrimer for Biocompatible, High-Efficiency DNA Delivery
    • Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM. Poly(ethylene glycol)-Conjugated PAMAM Dendrimer for Biocompatible, High-Efficiency DNA Delivery. Macromolecules 2002; 35: 3456-62.
    • (2002) Macromolecules , vol.35 , pp. 3456-3462
    • Luo, D.1    Haverstick, K.2    Belcheva, N.3    Han, E.4    Saltzman, W.M.5
  • 63
    • 0032044068 scopus 로고    scopus 로고
    • An overview of progress in antisense therapeutics
    • Crooke ST. An overview of progress in antisense therapeutics. Antisense Nucleic Acid Drug Dev 1998; 8:115-22.
    • (1998) Antisense Nucleic Acid Drug Dev , vol.8 , pp. 115-122
    • Crooke, S.T.1
  • 64
    • 0028943759 scopus 로고
    • Antigene, ribozyme and aptamer nucleic acid drugs: Progress and prospects
    • Stull RA Jr, Szoka FC Jr. Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharm Res 1995; 12: 465-83.
    • (1995) Pharm Res , vol.12 , pp. 465-483
    • Stull Jr., R.A.1    Szoka Jr., F.C.2
  • 65
    • 27644529720 scopus 로고    scopus 로고
    • DNA-based Biopharmaceuticals: Therapeutics for the 21st Century
    • Patil SD, Burgess DJ. DNA-based Biopharmaceuticals: therapeutics for the 21st Century. AAPS Newsmagazine 2003; 6: 27.
    • (2003) AAPS Newsmagazine , vol.6 , pp. 27
    • Patil, S.D.1    Burgess, D.J.2
  • 66
    • 19444375104 scopus 로고    scopus 로고
    • DNA-based Therapeutics and DNA Delivery Systems: A Comprehensive Review
    • Patil SD, Rhodes DG, Burgess DJ. DNA-based Therapeutics and DNA Delivery Systems: A Comprehensive Review. AAPS J 2005; 07: E61-E77.
    • (2005) AAPS J , vol.7
    • Patil, S.D.1    Rhodes, D.G.2    Burgess, D.J.3
  • 67
    • 0035914989 scopus 로고    scopus 로고
    • Intracellular trafficking and transgene expression of viral and non-viral gene vectors
    • Kamiya H, Tsuchiya H, Yamazaki J, Harashima H. Intracellular trafficking and transgene expression of viral and non-viral gene vectors. Adv Drug Deliv Rev 2001; 52: 153-64.
    • (2001) Adv Drug Deliv Rev , vol.52 , pp. 153-164
    • Kamiya, H.1    Tsuchiya, H.2    Yamazaki, J.3    Harashima, H.4
  • 68
    • 0035813684 scopus 로고    scopus 로고
    • Chitosans for gene delivery
    • Borchard G. Chitosans for gene delivery. Adv Drug Deliv Rev 2001; 52: 145-50.
    • (2001) Adv Drug Deliv Rev , vol.52 , pp. 145-150
    • Borchard, G.1
  • 69
    • 0035039412 scopus 로고    scopus 로고
    • Polyethylenimines for in vivo gene delivery
    • Lemkine GF, Demeneix BA. Polyethylenimines for in vivo gene delivery. Curr Opin Mol Ther 2001; 3: 178-82.
    • (2001) Curr Opin Mol Ther , vol.3 , pp. 178-182
    • Lemkine, G.F.1    Demeneix, B.A.2
  • 71
    • 2342565008 scopus 로고    scopus 로고
    • Enhanced cellular uptake of a triplex-forming oligonucleotide by nanoparticle formation in the presence of polypropyleneimine dendrimers
    • Latha M. Santhakumaran, Thresia Thomasand T.J. Thomas. Enhanced cellular uptake of a triplex-forming oligonucleotide by nanoparticle formation in the presence of polypropyleneimine dendrimers. Nucleic Acids Research 2004; 32: 2102-12.
    • (2004) Nucleic Acids Research , vol.32 , pp. 2102-2112
    • Santhakumaran, L.M.1    Thomas, T.T.T.J.2
  • 73
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan T, Kopecek J, Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev 2002; 54: 715-58.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 75
    • 0036021902 scopus 로고    scopus 로고
    • Viruses as gene delivery vectors: Application to gene function, target validation, and assay development
    • Lotze MT, Kost TA. Viruses as gene delivery vectors: application to gene function, target validation, and assay development. Cancer Gene Ther 2002; 9: 692-9.
    • (2002) Cancer Gene Ther , vol.9 , pp. 692-699
    • Lotze, M.T.1    Kost, T.A.2
  • 76
    • 0035028217 scopus 로고    scopus 로고
    • Cationic polymers for gene delivery: Designs for overcoming barriers to systemic administration
    • Hwang SJ, Davis ME. Cationic polymers for gene delivery: designs for overcoming barriers to systemic administration. Curr Opin Mol Ther 2001; 3: 183-91.
    • (2001) Curr Opin Mol Ther , vol.3 , pp. 183-191
    • Hwang, S.J.1    Davis, M.E.2
  • 77
    • 0035667722 scopus 로고    scopus 로고
    • Immediate and long-term safety of recombinant adenoassociated virus injection into the nonhuman primate muscle
    • Favre D, Provost N, Blouin V, Blancho G, Cherel Y, Salvetti A, et al. Immediate and long-term safety of recombinant adenoassociated virus injection into the nonhuman primate muscle. Mol Ther 2001; 4: 559-66.
    • (2001) Mol Ther , vol.4 , pp. 559-566
    • Favre, D.1    Provost, N.2    Blouin, V.3    Blancho, G.4    Cherel, Y.5    Salvetti, A.6
  • 78
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay MA, Glorioso JC, Naldini L. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 2001; 7: 33-40.
    • (2001) Nat Med , vol.7 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 79
    • 0032020501 scopus 로고    scopus 로고
    • Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice
    • Timme TL, Hall SJ, Barrios R, Woo SLC, AguilarCordova E, Thompson TC. Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice. Cancer Gene Ther 1998; 5: 74-82.
    • (1998) Cancer Gene Ther , vol.5 , pp. 74-82
    • Timme, T.L.1    Hall, S.J.2    Barrios, R.3    Woo, S.L.C.4    AguilarCordova, E.5    Thompson, T.C.6
  • 80
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP, et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003; 80: 148-58.
    • (2003) Mol Genet Metab , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6
  • 81
    • 0027511923 scopus 로고
    • Some effects of chitosan on liver function in the rat
    • LeHoux JG, Grondin F. Some effects of chitosan on liver function in the rat. Endocrinology 1993; 132: 1078-84.
    • (1993) Endocrinology , vol.132 , pp. 1078-1084
    • LeHoux, J.G.1    Grondin, F.2
  • 82
    • 0032473410 scopus 로고    scopus 로고
    • Polylysine-based transfection systems utilizing receptor-mediated delivery
    • Zauner W, Ogris M, Wagner E. Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv Drug Deliv Rev 1998; 30: 97-113.
    • (1998) Adv Drug Deliv Rev , vol.30 , pp. 97-113
    • Zauner, W.1    Ogris, M.2    Wagner, E.3
  • 83
    • 0001361923 scopus 로고
    • Synthetic gene-transfer vectors
    • Behr JP. Synthetic gene-transfer vectors. Acc Chem Res 1993; 26: 274-8.
    • (1993) Acc Chem Res , vol.26 , pp. 274-278
    • Behr, J.P.1
  • 84
    • 0029147628 scopus 로고
    • Nonviral gene therapy: The promise of genes as pharmaceutical products
    • Ledley FD. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum Gene Ther 1995; 6: 1129-44.
    • (1995) Hum Gene Ther , vol.6 , pp. 1129-1144
    • Ledley, F.D.1
  • 85
    • 0029801424 scopus 로고    scopus 로고
    • Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers
    • Wolfert MA, Schacht EH, Toncheva V, Ulbrich K. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 1996; 7: 2123-33.
    • (1996) Hum Gene Ther , vol.7 , pp. 2123-2133
    • Wolfert, M.A.1    Schacht, E.H.2    Toncheva, V.3    Ulbrich, K.4
  • 86
    • 52449135231 scopus 로고    scopus 로고
    • Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures
    • Florea BI, Meaney C, Junginger HE, Borchard G. Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures. AAPS PharmSci 2002; 4: E12.
    • (2002) AAPS PharmSci , vol.4
    • Florea, B.I.1    Meaney, C.2    Junginger, H.E.3    Borchard, G.4
  • 87
    • 0037023931 scopus 로고    scopus 로고
    • Measuring the pH environment of DNA delivered using nonviral vectors: Implications for lysosomal trafficking
    • Akinc A, Langer R. Measuring the pH environment of DNA delivered using nonviral vectors: implications for lysosomal trafficking. Biotechnol Bioengg 2002; 78: 503-8.
    • (2002) Biotechnol Bioengg , vol.78 , pp. 503-508
    • Akinc, A.1    Langer, R.2
  • 89
    • 0036730299 scopus 로고    scopus 로고
    • Modification of PLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo
    • Ward CM, Pechar M, Oupicky D, Ulbrich K, Seymour LW. Modification of PLL/ DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. J Gene Med 2002; 4: 536-47.
    • (2002) J Gene Med , vol.4 , pp. 536-547
    • Ward, C.M.1    Pechar, M.2    Oupicky, D.3    Ulbrich, K.4    Seymour, L.W.5
  • 90
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery systems
    • Luo D, Saltzman WM. Synthetic DNA delivery systems. Nat Biotechnol 2000; 18: 33-7.
    • (2000) Nat Biotechnol , vol.18 , pp. 33-37
    • Luo, D.1    Saltzman, W.M.2
  • 94
    • 0033200186 scopus 로고    scopus 로고
    • Complexing with Polyamidoamine Dendrimers: Implications for Transfection
    • Bielinska AU, Chen CL, Johnson J, Baker JR. Complexing with Polyamidoamine Dendrimers: Implications for Transfection. Bioconjugate Chem 1999; 10: 843-50.
    • (1999) Bioconjugate Chem , vol.10 , pp. 843-850
    • Bielinska, A.U.1    Chen, C.L.2    Johnson, J.3    Baker, J.R.4
  • 95
    • 0029160083 scopus 로고
    • A Versatile Vector for Gene and Oligonucleotide Transfer into Cells in Culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B, et al. A Versatile Vector for Gene and Oligonucleotide Transfer into Cells in Culture and in vivo: Polyethylenimine. Proc Natl Acad Sci USA 1995; 92: 7297-301.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'h, F.2    Zanta, M.A.3    Mergny, M.D.4    Scherman, D.5    Demeneix, B.6
  • 96
    • 0001703760 scopus 로고    scopus 로고
    • Synthesis of a Barbelllike Triblock Copolymer, Poly (L-lysine) Dendrimer-blockpoly(ethylene glycol)-block-Poly(L-lysine) Dendrimer, and Its Self-Assembly with Plasmid DNA
    • Choi JS, Joo DK, Kim CH, Kim K, Park JS. Synthesis of a Barbelllike Triblock Copolymer, Poly (L-lysine) Dendrimer-blockpoly(ethylene glycol)-block-Poly(L-lysine) Dendrimer, and Its Self-Assembly with Plasmid DNA. J Am Chem Soc 2000; 122: 474-80.
    • (2000) J Am Chem Soc , vol.122 , pp. 474-480
    • Choi, J.S.1    Joo, D.K.2    Kim, C.H.3    Kim, K.4    Park, J.S.5
  • 97
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick KA, Baldeschwieler JD. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 1996; 93: 12349-54.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 99
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/ transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schuller S, Kircheis R, Wagner E. PEGylated DNA/ transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 1999; 6: 595-605.
    • (1999) Gene Ther , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 101
    • 0031953132 scopus 로고    scopus 로고
    • In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA /DNA oligonucleotides
    • Kren BT, Bandyopadhyay P, Steer CJ. In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides. Nat Med 1998; 4: 285-90.
    • (1998) Nat Med , vol.4 , pp. 285-290
    • Kren, B.T.1    Bandyopadhyay, P.2    Steer, C.J.3
  • 102
    • 0030462391 scopus 로고    scopus 로고
    • Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
    • Boussif O, Zanta MA, Behr JP. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther 1996; 3: 1074-80.
    • (1996) Gene Ther , vol.3 , pp. 1074-1080
    • Boussif, O.1    Zanta, M.A.2    Behr, J.P.3
  • 103
    • 0031860769 scopus 로고    scopus 로고
    • Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system
    • Goula D, Remy JS, Erbacher P, Wasowicz M, Levi G, Abdallah B, et al. Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther 1998; 5: 712-7.
    • (1998) Gene Ther , vol.5 , pp. 712-717
    • Goula, D.1    Remy, J.S.2    Erbacher, P.3    Wasowicz, M.4    Levi, G.5    Abdallah, B.6
  • 104
    • 33947604820 scopus 로고    scopus 로고
    • Kirchler A, Behr JP Erbacher P, Huang L, Hung MC, Wagner E (Eds.). Academic Press, San Diago, CA
    • Kirchler A, Behr JP, Erbacher P, Huang L, Hung MC, Wagner E (Eds.). Non-viral vector for gene therapy, Academic Press, San Diago, CA 1999: 191-06.
    • (1999) Non-viral Vector for Gene Therapy , pp. 191-206
  • 105
  • 106
    • 0037122695 scopus 로고    scopus 로고
    • Development of non-viral vectors for systemic gene delivery
    • Liu F, Huang L. Development of non-viral vectors for systemic gene delivery. J Control Release 2002; 78: 259-66.
    • (2002) J Control Release , vol.78 , pp. 259-266
    • Liu, F.1    Huang, L.2
  • 107
    • 0033758920 scopus 로고    scopus 로고
    • Biodistribution and transgene expression with nonviral cationic vector /DNA complexes in the lungs
    • Bragonnzi A, Dina G, Villa A, Calori G, Biffi A, Bordignon C, et al. Conese M. Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs. Gene Ther 2000; 7: 1753-60.
    • (2000) Gene Ther , vol.7 , pp. 1753-1760
    • Bragonnzi, A.1    Dina, G.2    Villa, A.3    Calori, G.4    Biffi, A.5    Bordignon, C.6    Conese, M.7
  • 108
    • 0033980841 scopus 로고    scopus 로고
    • Evaluation of polyether-polyethylenimine graft copolymers as gene transfer agents
    • Nguyen HK. Evaluation of polyether-polyethylenimine graft copolymers as gene transfer agents. Gene Ther 2000; 7: 126-38.
    • (2000) Gene Ther , vol.7 , pp. 126-138
    • Nguyen, H.K.1
  • 109
    • 0031239718 scopus 로고    scopus 로고
    • Water-Soluble Polyion Complex Associates of DNA and Poly(ethylene glycol)-Poly(L-lysine) Block Copolymer
    • Katayose S, Kataoka K. Water-Soluble Polyion Complex Associates of DNA and Poly(ethylene glycol)-Poly(L-lysine) Block Copolymer. Bioconjugate Chem 1997; 8: 702-7.
    • (1997) Bioconjugate Chem , vol.8 , pp. 702-707
    • Katayose, S.1    Kataoka, K.2
  • 110
    • 0002863889 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-block-poly(L-lysine) Dendrimer: Novel Linear Polymer/Dendrimer Block Copolymer Forming a Spherical Water-Soluble Polyionic Complex with DNA
    • Choi JS, Lee EJ, Choi YH, Jeong YJ, Park JS. Poly(ethylene glycol)-block-poly(L-lysine) Dendrimer: Novel Linear Polymer/Dendrimer Block Copolymer Forming a Spherical Water-Soluble Polyionic Complex with DNA. Bioconjugate Chem 1999; 10: 62-5.
    • (1999) Bioconjugate Chem , vol.10 , pp. 62-65
    • Choi, J.S.1    Lee, E.J.2    Choi, Y.H.3    Jeong, Y.J.4    Park, J.S.5
  • 112
    • 0035170578 scopus 로고    scopus 로고
    • Material for non viral gene delivery
    • Segura T, Shea LD. Material for non viral gene delivery. Annu Rev Mater Res 2001; 31: 25-46.
    • (2001) Annu Rev Mater Res , vol.31 , pp. 25-46
    • Segura, T.1    Shea, L.D.2
  • 113
    • 0037130553 scopus 로고    scopus 로고
    • Structure-activity relationships of Poly(L-lysine): Effects of PEGylation and molecular shape on physiochemical and biological properties in gene delivery
    • Mannisto M, Vanderkerken S, Toncheva V, Elomaa M, Ruponen M, Schacht E, et al. Structure-activity relationships of Poly(L-lysine): effects of PEGylation and molecular shape on physiochemical and biological properties in gene delivery. J Control Release 2002; 83: 169-82.
    • (2002) J Control Release , vol.83 , pp. 169-182
    • Mannisto, M.1    Vanderkerken, S.2    Toncheva, V.3    Elomaa, M.4    Ruponen, M.5    Schacht, E.6
  • 114
    • 33748994569 scopus 로고    scopus 로고
    • Influence of Polyethylene Glycol chain length on the physiochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes
    • Mao S, Neu M, Germershaus O, Merkel O, Sitterberg J, Bakowsky U, Kissel T. Influence of Polyethylene Glycol chain length on the physiochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes. Bioconjugate chem 2006; 17: 1209-18.
    • (2006) Bioconjugate Chem , vol.17 , pp. 1209-1218
    • Mao, S.1    Neu, M.2    Germershaus, O.3    Merkel, O.4    Sitterberg, J.5    Bakowsky, U.6    Kissel, T.7
  • 115
    • 0035286969 scopus 로고    scopus 로고
    • Polyethyleniminemediated gene delivery: A mechanistic study
    • Kirchler A, Leborgne C, Coeytaux E, Danos O. Polyethyleniminemediated gene delivery: a mechanistic study J Gene Med 2001; 3: 135-44.
    • (2001) J Gene Med , vol.3 , pp. 135-144
    • Kirchler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 116
    • 0030293017 scopus 로고    scopus 로고
    • In vitro Gene Delivery by Degraded Polyamidoamine Dendrimers
    • Tang MX, Redemann CT, Szoka FC. In vitro Gene Delivery by Degraded Polyamidoamine Dendrimers. Bioconjugate Chem 1996; 7: 703-14.
    • (1996) Bioconjugate Chem , vol.7 , pp. 703-714
    • Tang, M.X.1    Redemann, C.T.2    Szoka, F.C.3
  • 117
    • 17644395605 scopus 로고    scopus 로고
    • Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting
    • Bhadra D, Yadav AK, Bhadra S, Jain NK. Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting. Int J Pharm 2005; 295: 221-33.
    • (2005) Int J Pharm , vol.295 , pp. 221-233
    • Bhadra, D.1    Yadav, A.K.2    Bhadra, S.3    Jain, N.K.4
  • 118
    • 0028042356 scopus 로고
    • Encapsulation of guest molecules into a dendritic box
    • Jansen JFGA. Encapsulation of guest molecules into a dendritic box. Science 1994; 266: 1226-9.
    • (1994) Science , vol.266 , pp. 1226-1229
    • Jansen, J.F.G.A.1
  • 119
  • 120
    • 0000950412 scopus 로고    scopus 로고
    • Recent developments in the rational design of multivalent glycoconjugates
    • Roy R, Recent developments in the rational design of multivalent glycoconjugates. Top Curr Chem 1997; 187: 241-74.
    • (1997) Top Curr Chem , vol.187 , pp. 241-274
    • Roy, R.1
  • 121
    • 33748217724 scopus 로고
    • Novel polyether copolymers consisting of linear and dendritic blocks
    • Gitsov I, Wooley KL, Frechet JMJ. Novel polyether copolymers consisting of linear and dendritic blocks. Angew Chem Int Ed Engl 1992; 31:1200-2.
    • (1992) Angew Chem Int Ed Engl , vol.31 , pp. 1200-1202
    • Gitsov, I.1    Wooley, K.L.2    Frechet, J.M.J.3
  • 122
    • 33644889388 scopus 로고    scopus 로고
    • PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate
    • Bhadra D, Bhadra S, Jain NK. PEGylated peptide dendrimeric carriers for the delivery of antimalarial drug chloroquine phosphate. Pharm Res 2006; 23: 623-33.
    • (2006) Pharm Res , vol.23 , pp. 623-633
    • Bhadra, D.1    Bhadra, S.2    Jain, N.K.3
  • 123
    • 33645102601 scopus 로고    scopus 로고
    • In vitro enzymatic stability of dendritic peptides
    • Yang H, Lopina ST. In vitro enzymatic stability of dendritic peptides. J Biomed Mater Res A 2006; 76: 398-407.
    • (2006) J Biomed Mater Res A , vol.76 , pp. 398-407
    • Yang, H.1    Lopina, S.T.2
  • 124
    • 0036000121 scopus 로고    scopus 로고
    • Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and Characterization
    • Ihre HR, Padilla De Jesus OL, Szoka FC Jr, Frechet JMJ. Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and Characterization. Bioconjugate Chem 2002; 13: 443-52.
    • (2002) Bioconjugate Chem , vol.13 , pp. 443-452
    • Ihre, H.R.1    Padilla De Jesus, O.L.2    Szoka Jr., F.C.3    Frechet, J.M.J.4
  • 125
    • 33947585092 scopus 로고    scopus 로고
    • PEGylated Dendritic Architecture for Development of a Prolonged Drug Delivery System for an Antitubercular Drug
    • article in press
    • Vijayaraj Kumar P, Agashe H, Dutta T, Jain N K. PEGylated Dendritic Architecture for Development of a Prolonged Drug Delivery System for an Antitubercular Drug. Curr Drug Del 2006; article in press.
    • (2006) Curr Drug Del
    • Vijayaraj Kumar, P.1    Agashe, H.2    Dutta, T.3    Jain, N.K.4
  • 126
    • 0033800262 scopus 로고    scopus 로고
    • Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: A potential oral delivery system
    • Wiwattanapatapee R, Carreno-Gomez B, Malik N, Duncan R. Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: a potential oral delivery system. Pharm Res 2000; 17: 991-8.
    • (2000) Pharm Res , vol.17 , pp. 991-998
    • Wiwattanapatapee, R.1    Carreno-Gomez, B.2    Malik, N.3    Duncan, R.4
  • 127
    • 2942613703 scopus 로고    scopus 로고
    • Transport of dendrimer nanocarriers through epithelial cells via the transcellular route
    • Jevprasesphant R, Penny J, Attwood, D, D'Emanuele A. Transport of dendrimer nanocarriers through epithelial cells via the transcellular route. J Control Release 2004; 97: 259-67.
    • (2004) J Control Release , vol.97 , pp. 259-267
    • Jevprasesphant, R.1    Penny, J.2    Attwood, D.3    D'Emanuele, A.4
  • 128
    • 0141867744 scopus 로고    scopus 로고
    • Transport mechanism(s) of poly (amidoamine) dendrimers across Caco-2 cell monolayers
    • El-Sayed M, Rhodes CA, Ginski M, Ghandehari H. Transport mechanism(s) of poly (amidoamine) dendrimers across Caco-2 cell monolayers. Int J Pharm 2003; 265: 151-7.
    • (2003) Int J Pharm , vol.265 , pp. 151-157
    • El-Sayed, M.1    Rhodes, C.A.2    Ginski, M.3    Ghandehari, H.4
  • 130
    • 1642443337 scopus 로고    scopus 로고
    • Acid- and salt-triggered multifunctional poly(propylene imine) dendrimer as a prospective drug delivery system
    • Paleos C M, Tsiourvas D, Sideratou Z, Tziveleka L, Acid- and salt-triggered multifunctional poly(propylene imine) dendrimer as a prospective drug delivery system. Biomacromolecules 2004; 5: 524-9.
    • (2004) Biomacromolecules , vol.5 , pp. 524-529
    • Paleos, C.M.1    Tsiourvas, D.2    Sideratou, Z.3    Tziveleka, L.4
  • 131
    • 0026689081 scopus 로고
    • Magnetic resonance imaging detection of an experimental pulmonary perfusion deficit using a macromolecular contrast agent. Polylysine-gadolinium-DTPA40
    • Berthezene Y, Vexler V, Price DC, Wisner-Dupon J, Moseley ME, Aicher, KP, et al. Magnetic resonance imaging detection of an experimental pulmonary perfusion deficit using a macromolecular contrast agent. Polylysine-gadolinium-DTPA40. Invest Radiol 1992; 27: 346-51.
    • (1992) Invest Radiol , vol.27 , pp. 346-351
    • Berthezene, Y.1    Vexler, V.2    Price, D.C.3    Wisner-Dupon, J.4    Moseley, M.E.5    Aicher, K.P.6
  • 133
    • 0000111096 scopus 로고    scopus 로고
    • Evaluation of the effects of intravascular MR contrast media (gadolinium dendrimer) on 3D time of flight magnetic resonance angiography of the body
    • Bourne MW, Margerun L, Hylton N, Campion B, Lai JJ, Derugin N, et al. Evaluation of the effects of intravascular MR contrast media (gadolinium dendrimer) on 3D time of flight magnetic resonance angiography of the body. J Magn Reson Imaging 1996; 6: 305-10.
    • (1996) J Magn Reson Imaging , vol.6 , pp. 305-310
    • Bourne, M.W.1    Margerun, L.2    Hylton, N.3    Campion, B.4    Lai, J.J.5    Derugin, N.6
  • 134
    • 0344766109 scopus 로고    scopus 로고
    • Synthesis and relaxometry of high-generation (G 5 5, 7, 9, and 10) PAMAM™ dendrimer-DOTA-gadolinium chelates
    • Bryant Jr LH, Brechbiel MW, Wu C, Bulte JW, Herynek V, Frank JA. Synthesis and relaxometry of high-generation (G 5 5, 7, 9, and 10) PAMAM™ dendrimer-DOTA-gadolinium chelates. J Magn Reson Imaging 1999; 9: 348-52.
    • (1999) J Magn Reson Imaging , vol.9 , pp. 348-352
    • Bryant Jr., L.H.1    Brechbiel, M.W.2    Wu, C.3    Bulte, J.W.4    Herynek, V.5    Frank, J.A.6
  • 135
    • 0035105015 scopus 로고    scopus 로고
    • 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with references to their pharmacokinetic properties
    • Kobayashi H, Sato N, Hiraga A, Saga T, Nakamoto Y, Ueda H, et al. 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with references to their pharmacokinetic properties. Magn Reson Med 2001; 45: 454-60.
    • (2001) Magn Reson Med , vol.45 , pp. 454-460
    • Kobayashi, H.1    Sato, N.2    Hiraga, A.3    Saga, T.4    Nakamoto, Y.5    Ueda, H.6
  • 136
    • 0034789562 scopus 로고    scopus 로고
    • Positive Effects of Polyethylene Glycol Conjugation to Generation-4 Polyamidoamine Dendrimers as Macromolecular MR Contrast Agents
    • Kabayashi H, Kamamoto S, Saga T, Sato N, Hiraga A, Ishimori T, et al. Positive Effects of Polyethylene Glycol Conjugation to Generation-4 Polyamidoamine Dendrimers as Macromolecular MR Contrast Agents; Magn Reson Med 2001; 46: 781-8.
    • (2001) Magn Reson Med , vol.46 , pp. 781-788
    • Kabayashi, H.1    Kamamoto, S.2    Saga, T.3    Sato, N.4    Hiraga, A.5    Ishimori, T.6
  • 137
    • 0035470241 scopus 로고    scopus 로고
    • Dendritic Catalysts and Dendrimers in Catalysis
    • Astruc D, Chardac F. Dendritic Catalysts and Dendrimers in Catalysis. Chem Rev 2001; 101: 2991-3024.
    • (2001) Chem Rev , vol.101 , pp. 2991-3024
    • Astruc, D.1    Chardac, F.2
  • 139
    • 0034665833 scopus 로고    scopus 로고
    • Functionalization of a Poly (amidoamine) Dendrimer with Ferrocenyls and Its Application to the Construction of a Reagentless Enzyme Electrode
    • Yoon HC, Hong MY, Kim HS. Functionalization of a Poly (amidoamine) Dendrimer with Ferrocenyls and Its Application to the Construction of a Reagentless Enzyme Electrode. Anal Chem 2000; 72: 4420-7.
    • (2000) Anal Chem , vol.72 , pp. 4420-4427
    • Yoon, H.C.1    Hong, M.Y.2    Kim, H.S.3
  • 140
    • 0034660578 scopus 로고    scopus 로고
    • Affinity Biosensor for Avidin Using a Double Functionalized Dendrimer Monolayer on a Gold Electrode
    • Yoon HC, Hong MY, Kim HS, Affinity Biosensor for Avidin Using a Double Functionalized Dendrimer Monolayer on a Gold Electrode. Anal Biochem 2000; 282: 121-8.
    • (2000) Anal Biochem , vol.282 , pp. 121-128
    • Yoon, H.C.1    Hong, M.Y.2    Kim, H.S.3
  • 143
    • 1842535270 scopus 로고    scopus 로고
    • The design and development of pegfilgrastim (PEGrmetHuG-CSF, Neulasta)
    • Molineux G. The design and development of pegfilgrastim (PEGrmetHuG-CSF, Neulasta). Curr Pharm Des 2004; 10(11): 1235-44.
    • (2004) Curr Pharm Des , vol.10 , Issue.11 , pp. 1235-1244
    • Molineux, G.1


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