The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis

Breast Cancer Research and Treatment

Volumn 81, Issue 2, 2003, Pages 137-147

  Colpaert, Cecile G ^a   Vermeulen, Peter B ^a,b   Fox, Stephen B ^c   Harris, Adrian L ^c   Dirix, Luc Y ^b   Van Marck, Eric A ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b Translational Cancer Research Group   (Belgium)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Breast cancer; Carbonic anhydrase IX; Fibrotic focus; Hypoxia; Intra tumoral fibroblasts

Indexed keywords

CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE IX; TUMOR MARKER; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; BREAST CARCINOMA; CANCER GROWTH; CANCER INVASION; CANCER RECURRENCE; CANCER SURVIVAL; CARCINOMA CELL; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DENSITY; DISEASE MARKER; ENDOTHELIUM CELL; FEMALE; FIBROBLAST; FIBROSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; MEDICAL PARAMETERS; MICROVASCULATURE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SCORING SYSTEM;

ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CARBONIC ANHYDRASES; CARCINOMA, DUCTAL; CELL HYPOXIA; FEMALE; FIBROSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GREAT BRITAIN; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM PROTEINS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 0141751743     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025702330207     Document Type: Article

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