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Volumn 118, Issue 10, 2006, Pages 2609-2616

Hypoxia inducible factor-1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response

Author keywords

Breast cancer; HIF 1 ; Prognosis; Tamoxifen treatment

Indexed keywords

CYCLIN E; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; TAMOXIFEN; VASCULOTROPIN A;

EID: 33646423829     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.21676     Document Type: Article
Times cited : (74)

References (40)
  • 3
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang CV, Semenza GL. Oncogenic alterations of metabolism. Trends Biochem Sci 1999;24:68-72.
    • (1999) Trends Biochem Sci , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 4
    • 0345707572 scopus 로고    scopus 로고
    • Oxygenation gain factor: A novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers
    • Vaupel P, Mayer A, Briest S, Hockel M. Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers. Cancer Res 2003;63:7634-7.
    • (2003) Cancer Res , vol.63 , pp. 7634-7637
    • Vaupel, P.1    Mayer, A.2    Briest, S.3    Hockel, M.4
  • 5
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999;15:551-78.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 8
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 9
    • 0032169214 scopus 로고    scopus 로고
    • Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT
    • Zelzer E, Levy Y, Kahana C, Shilo BZ, Rubinstein M, Cohen B. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1α/ARNT. EMBO J 1998;17:5085-94.
    • (1998) EMBO J , vol.17 , pp. 5085-5094
    • Zelzer, E.1    Levy, Y.2    Kahana, C.3    Shilo, B.Z.4    Rubinstein, M.5    Cohen, B.6
  • 10
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 2001;21:3995-4004.
    • (2001) Mol Cell Biol , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 11
    • 0035477438 scopus 로고    scopus 로고
    • Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α, HIF-2α, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway
    • Blancher C, Moore JW, Robertson N, Harris AL. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1α, HIF-2α, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway. Cancer Res 2001;61:7349-55.
    • (2001) Cancer Res , vol.61 , pp. 7349-7355
    • Blancher, C.1    Moore, J.W.2    Robertson, N.3    Harris, A.L.4
  • 15
    • 16644373473 scopus 로고    scopus 로고
    • Role of VHL gene mutation in human cancer
    • Kim WY, Kaelin WG. Role of VHL gene mutation in human cancer. J Clin Oncol 2004;22:4991-5004.
    • (2004) J Clin Oncol , vol.22 , pp. 4991-5004
    • Kim, W.Y.1    Kaelin, W.G.2
  • 16
    • 11144337759 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Regulation by hypoxic and non-hypoxic activators
    • Dery MA, Michaud MD, Richard DE. Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int J Biochem Cell Biol 2005;37:535-40.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 535-540
    • Dery, M.A.1    Michaud, M.D.2    Richard, D.E.3
  • 17
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM, Wilson WR. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 2004;4:437-47.
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 20
    • 0036795452 scopus 로고    scopus 로고
    • Hypoxia induces proteasome-dependent degradation of estrogen receptor α in ZR-75 breast cancer cells
    • Stoner M, Saville B, Wormke M, Dean D, Burghardt R, Safe S. Hypoxia induces proteasome-dependent degradation of estrogen receptor α in ZR-75 breast cancer cells. Mol Endocrinol 2002;16:2231-42.
    • (2002) Mol Endocrinol , vol.16 , pp. 2231-2242
    • Stoner, M.1    Saville, B.2    Wormke, M.3    Dean, D.4    Burghardt, R.5    Safe, S.6
  • 21
    • 0043124314 scopus 로고    scopus 로고
    • Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-α expression in human breast cancer
    • Kronblad A, Helczynska K, Nielsen NH, Pahlman E, Emdin S, Pahlman S, Landberg G. Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-α expression in human breast cancer. In Vivo 2003;17:311-8.
    • (2003) In Vivo , vol.17 , pp. 311-318
    • Kronblad, A.1    Helczynska, K.2    Nielsen, N.H.3    Pahlman, E.4    Emdin, S.5    Pahlman, S.6    Landberg, G.7
  • 22
    • 11144231029 scopus 로고    scopus 로고
    • Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor-α in human breast carcinoma
    • Cooper C, Liu GY, Niu YL, Santos S, Murphy LC, Watson PH. Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor-α in human breast carcinoma. Clin Cancer Res 2004;10:8720-7.
    • (2004) Clin Cancer Res , vol.10 , pp. 8720-8727
    • Cooper, C.1    Liu, G.Y.2    Niu, Y.L.3    Santos, S.4    Murphy, L.C.5    Watson, P.H.6
  • 23
    • 17844400028 scopus 로고    scopus 로고
    • Cobalt chloride-induced estrogen receptor -α downregulation involves hypoxiu-inducible factor-1α in MCF-7 human breast cancer cells
    • Cho J, Kim D, Lee S, Lee Y. Cobalt chloride-induced estrogen receptor -α downregulation involves hypoxiu-inducible factor-1α in MCF-7 human breast cancer cells. Mol Endocrinol 2005;19:1191-9.
    • (2005) Mol Endocrinol , vol.19 , pp. 1191-1199
    • Cho, J.1    Kim, D.2    Lee, S.3    Lee, Y.4
  • 24
    • 0034759792 scopus 로고    scopus 로고
    • Hypoxia reduces hormone responsiveness of human breast cancer cells
    • Kurebayashi J, Otsuki T, Moriya T, Sonoo H. Hypoxia reduces hormone responsiveness of human breast cancer cells. Jpn J Cancer Res 2001;92:1093-101.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 1093-1101
    • Kurebayashi, J.1    Otsuki, T.2    Moriya, T.3    Sonoo, H.4
  • 25
    • 0037241504 scopus 로고    scopus 로고
    • Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer
    • Johnston SR, Head J, Pancholi S, Detre S, Martin LA, Smith IE, Dowsett M. Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. Clin Cancer Res 2003;9(1 Pt 2):524S-32S.
    • (2003) Clin Cancer Res , vol.9 , Issue.1 PART 2
    • Johnston, S.R.1    Head, J.2    Pancholi, S.3    Detre, S.4    Martin, L.A.5    Smith, I.E.6    Dowsett, M.7
  • 33
    • 4644312033 scopus 로고    scopus 로고
    • The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers
    • Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC, Fox SB. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br J Cancer 2004;91:954-8.
    • (2004) Br J Cancer , vol.91 , pp. 954-958
    • Chakrabarti, J.1    Turley, H.2    Campo, L.3    Han, C.4    Harris, A.L.5    Gatter, K.C.6    Fox, S.B.7
  • 34
    • 7044271020 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1α and cell cycle proteins in invasive breast cancer are estrogen receptor related
    • Bos R, van Diest PJ, van der Groep P, Shvarts A, Greijer AE, van der Wall E. Expression of hypoxia-inducible factor-1α and cell cycle proteins in invasive breast cancer are estrogen receptor related. Breast Cancer Res 2004;6:R450-R9.
    • (2004) Breast Cancer Res , vol.6
    • Bos, R.1    Van Diest, P.J.2    Van Der Groep, P.3    Shvarts, A.4    Greijer, A.E.5    Van Der Wall, E.6
  • 35
    • 0031023425 scopus 로고    scopus 로고
    • Deregulation of cyclin e and D1 in breast cancer is associated with inactivation of the retinoblastoma protein
    • Nielsen NH, Emdin SO, Cajander J, Landberg G. Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein. Oncogene 1997;14:295-304.
    • (1997) Oncogene , vol.14 , pp. 295-304
    • Nielsen, N.H.1    Emdin, S.O.2    Cajander, J.3    Landberg, G.4
  • 36
    • 0037063165 scopus 로고    scopus 로고
    • The cyclin D1 high and cyclin e high subgroups of breast cancer: Separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node
    • Loden M, Stighall M, Nielsen NH, Roos G, Emdin SO, Ostlund H, Landberg G. The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene 2002;21:4680-90.
    • (2002) Oncogene , vol.21 , pp. 4680-4690
    • Loden, M.1    Stighall, M.2    Nielsen, N.H.3    Roos, G.4    Emdin, S.O.5    Ostlund, H.6    Landberg, G.7
  • 37
    • 1442278675 scopus 로고    scopus 로고
    • Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor-α and SP proteins
    • Stoner M, Wormke M, Saville B, Samudio I, Qin C, Abdelrahim M, Safe S. Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor-α and SP proteins. Oncogene 2004;23:1052-63.
    • (2004) Oncogene , vol.23 , pp. 1052-1063
    • Stoner, M.1    Wormke, M.2    Saville, B.3    Samudio, I.4    Qin, C.5    Abdelrahim, M.6    Safe, S.7
  • 38
    • 0142117231 scopus 로고    scopus 로고
    • Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer
    • Dabrosin C, Margetts PJ, Gauldie J. Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer. Int J Cancer 2003;107:535-40.
    • (2003) Int J Cancer , vol.107 , pp. 535-540
    • Dabrosin, C.1    Margetts, P.J.2    Gauldie, J.3
  • 39
    • 0141455509 scopus 로고    scopus 로고
    • Interactions between estrogen and growth factor receptors in human breast cancers and the tumor-associated vasculature
    • Pietras RJ. Interactions between estrogen and growth factor receptors in human breast cancers and the tumor-associated vasculature. Breast J 2003;9:361-73.
    • (2003) Breast J , vol.9 , pp. 361-373
    • Pietras, R.J.1
  • 40
    • 2942511783 scopus 로고    scopus 로고
    • An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1
    • Elkin M, Orgel A, Kleinman HK. An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst 2004;96:875-8.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 875-878
    • Elkin, M.1    Orgel, A.2    Kleinman, H.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.