메뉴 건너뛰기




Volumn 7, Issue 1, 2007, Pages 7-23

New vectors and strategies for cardiovascular gene therapy

Author keywords

Angiogenesis; Endothelial progenitor cells; Heme oxygenase; Hypoxia inducible factor 1; Superoxide dismutase; Vascular endothelial growth factor

Indexed keywords

ADENOVIRUS VECTOR; ANGIOPOIETIN 1; ATENOLOL; BASIC FIBROBLAST GROWTH FACTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 22; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KALLIKREIN; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR; PLACEBO; PLATELET DERIVED GROWTH FACTOR BB; PR 39; PROPRANOLOL; RETROVIRUS VECTOR; SCATTER FACTOR; STAT PROTEIN; SUPEROXIDE DISMUTASE; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN 165; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN D;

EID: 33847304479     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652307779940243     Document Type: Review
Times cited : (20)

References (151)
  • 1
    • 3142735150 scopus 로고    scopus 로고
    • Pre-emptive gene therapy using recombinant adenoassociated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival
    • Agrawal, R.S., Muangman, S., Layne, M.D., Melo, L., Perrella, M.A., Lee, R.T., Hang, L., Lopez-Ilasaca, M., and Dzau, V.J. (2004) Pre-emptive gene therapy using recombinant adenoassociated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival. Gene Ther., 11: 962-969.
    • (2004) Gene Ther. , vol.11 , pp. 962-969
    • Agrawal, R.S.1    Muangman, S.2    Layne, M.D.3    Melo, L.4    Perrella, M.A.5    Lee, R.T.6    Hang, L.7    Lopez-Ilasaca, M.8    Dzau, V.J.9
  • 2
    • 0032548835 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells
    • Arkonac, B.M., Foster, L.C., Sibinga, N.E., Patterson, C., Lai, K., Tsai, J.C., Lee, M.E., Perrella, M.A., and Haber, E. (1998) Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells. J. Biol. Chem., 273: 4400-4405.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4400-4405
    • Arkonac, B.M.1    Foster, L.C.2    Sibinga, N.E.3    Patterson, C.4    Lai, K.5    Tsai, J.C.6    Lee, M.E.7    Perrella, M.A.8    Haber, E.9
  • 3
    • 0037689525 scopus 로고    scopus 로고
    • Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors
    • Arsic, N., Zentilin, L., Zacchigna, S., Santoro, D., Stanta, G., Salvi, A., Sinagra, G., and Giacca, M. (2003) Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors. Mol. Ther., 7: 450-459.
    • (2003) Mol. Ther. , vol.7 , pp. 450-459
    • Arsic, N.1    Zentilin, L.2    Zacchigna, S.3    Santoro, D.4    Stanta, G.5    Salvi, A.6    Sinagra, G.7    Giacca, M.8
  • 5
    • 12744272136 scopus 로고    scopus 로고
    • Cell-selective viral gene delivery vectors for the vasculature
    • Baker, A.H., Kritz, A., Work, L.M., and Nicklin, S.A. (2005) Cell-selective viral gene delivery vectors for the vasculature. Exp. Physiol., 90: 27-31.
    • (2005) Exp. Physiol. , vol.90 , pp. 27-31
    • Baker, A.H.1    Kritz, A.2    Work, L.M.3    Nicklin, S.A.4
  • 6
    • 0033007934 scopus 로고    scopus 로고
    • Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody
    • Bartlett, J.S., Kleinschmidt, J., Boucher, R.C., and Samulski, R.J. (1999) Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nat. Biotechnol., 17: 181-186.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 181-186
    • Bartlett, J.S.1    Kleinschmidt, J.2    Boucher, R.C.3    Samulski, R.J.4
  • 8
    • 0035038918 scopus 로고    scopus 로고
    • The well-tempered vessel
    • Blau, H. M., and Banfi, A. (2001) The well-tempered vessel. Nat. Med., 7: 532-534.
    • (2001) Nat. Med. , vol.7 , pp. 532-534
    • Blau, H.M.1    Banfi, A.2
  • 9
    • 0242637112 scopus 로고    scopus 로고
    • Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): Mechanistic insights from serial contrast-enhanced magnetic resonance imaging
    • Britten, M.B., Abolmaali, N.D., Assmus, B., Lehmann, R., Honold, J., Schmitt, J., Vogl, T.J., Martin, H., Schachinger, V., Dimmeler, S., and Zeiher, A.M. (2003) Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation, 108: 2212-2218.
    • (2003) Circulation , vol.108 , pp. 2212-2218
    • Britten, M.B.1    Abolmaali, N.D.2    Assmus, B.3    Lehmann, R.4    Honold, J.5    Schmitt, J.6    Vogl, T.J.7    Martin, H.8    Schachinger, V.9    Dimmeler, S.10    Zeiher, A.M.11
  • 11
    • 3542999278 scopus 로고    scopus 로고
    • VEGF links hippocampal activity with neurogenesis, learning and memory
    • Cao, L., Jiao, X., Zuzga, D.S., Liu, Y., Fong, D.M., Young, D., and During, M.J. (2004) VEGF links hippocampal activity with neurogenesis, learning and memory. Nat. Genet., 36: 827-835.
    • (2004) Nat. Genet. , vol.36 , pp. 827-835
    • Cao, L.1    Jiao, X.2    Zuzga, D.S.3    Liu, Y.4    Fong, D.M.5    Young, D.6    During, M.J.7
  • 12
    • 12344261807 scopus 로고    scopus 로고
    • Update on therapeutic neovascularization
    • Cao, Y., Hong, A., Schulten, H., and Post, M.J. (2005) Update on therapeutic neovascularization. Cardiovasc. Res., 65: 639-648.
    • (2005) Cardiovasc. Res. , vol.65 , pp. 639-648
    • Cao, Y.1    Hong, A.2    Schulten, H.3    Post, M.J.4
  • 13
    • 0038363443 scopus 로고    scopus 로고
    • Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
    • Cao, R., Brakenhielm, E., Pawliuk, R., Wariaro, D., Post, M.J., Wahlberg, E., Leboulch, P., and Cao, Y. (2003) Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat. Med., 9: 604-613.
    • (2003) Nat. Med. , vol.9 , pp. 604-613
    • Cao, R.1    Brakenhielm, E.2    Pawliuk, R.3    Wariaro, D.4    Post, M.J.5    Wahlberg, E.6    Leboulch, P.7    Cao, Y.8
  • 14
    • 10944271807 scopus 로고    scopus 로고
    • Efficacy of gene therapy for SCID is being confirmed
    • Cavazzana-Calvo, M., and Fischer, A. (2004) Efficacy of gene therapy for SCID is being confirmed. Lancet, 364: 2155-2156.
    • (2004) Lancet , vol.364 , pp. 2155-2156
    • Cavazzana-Calvo, M.1    Fischer, A.2
  • 17
    • 32944459983 scopus 로고    scopus 로고
    • Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain
    • Cearley, C.N., and Wolfe, J.H. (2006) Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain. Mol. Ther., 13: 528-537.
    • (2006) Mol. Ther. , vol.13 , pp. 528-537
    • Cearley, C.N.1    Wolfe, J.H.2
  • 18
    • 0034572459 scopus 로고    scopus 로고
    • Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors
    • Chao, H., Liu, Y., Rabinowitz, J., Li, C., Samulski, R.J., and Walsh, C.E. (2000) Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Mol. Ther., 2: 619-623.
    • (2000) Mol. Ther. , vol.2 , pp. 619-623
    • Chao, H.1    Liu, Y.2    Rabinowitz, J.3    Li, C.4    Samulski, R.J.5    Walsh, C.E.6
  • 19
    • 0034842912 scopus 로고    scopus 로고
    • Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors
    • Chao, H., Monahan, P.E., Liu, Y., Samulski, R.J., and Walsh, C.E. (2001) Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors. Mol. Ther., 4: 217-222.
    • (2001) Mol. Ther. , vol.4 , pp. 217-222
    • Chao, H.1    Monahan, P.E.2    Liu, Y.3    Samulski, R.J.4    Walsh, C.E.5
  • 21
    • 10344226206 scopus 로고    scopus 로고
    • Augmentation of therapeutic angiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3beta activity
    • Choi, J.H., Hur, J., Yoon, C.H., Kim, J.H., Lee, C.S., Youn, S.W., Oh, I.Y., Skurk, C., Murohara, T., Park, Y.B., Walsh, K., and Kim, H.S. (2004) Augmentation of therapeutic angiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3beta activity. J. Biol. Chem., 279: 49430-49438.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49430-49438
    • Choi, J.H.1    Hur, J.2    Yoon, C.H.3    Kim, J.H.4    Lee, C.S.5    Youn, S.W.6    Oh, I.Y.7    Skurk, C.8    Murohara, T.9    Park, Y.B.10    Walsh, K.11    Kim, H.S.12
  • 22
    • 21244491577 scopus 로고    scopus 로고
    • AAV hybrid serotypes: Improved vectors for gene delivery
    • Choi, V.W., McCarty, D.M., and Samulski, R.J. (2005) AAV hybrid serotypes: improved vectors for gene delivery. Curr. Gene Ther., 5: 299-310.
    • (2005) Curr. Gene Ther. , vol.5 , pp. 299-310
    • Choi, V.W.1    McCarty, D.M.2    Samulski, R.J.3
  • 23
    • 13944278472 scopus 로고    scopus 로고
    • Gene therapy. As Gelsinger case ends, gene therapy suffers another blow
    • Couzin, J., and Kaiser, J. (2005) Gene therapy. As Gelsinger case ends, gene therapy suffers another blow. Science, 307:1028.
    • (2005) Science , vol.307 , pp. 1028
    • Couzin, J.1    Kaiser, J.2
  • 25
    • 0027312173 scopus 로고
    • Molecular adaptation of cellular defences following preconditioning of the heart by repeated ischemia
    • Das, D.K., Engelman, R.M., and Kimura, Y. (1993) Molecular adaptation of cellular defences following preconditioning of the heart by repeated ischemia. Cardiovasc. Res., 27: 578-84.
    • (1993) Cardiovasc. Res. , vol.27 , pp. 578-584
    • Das, D.K.1    Engelman, R.M.2    Kimura, Y.3
  • 26
    • 0034724209 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system
    • Davidson, B., Stein, C., Heth, J., Martins, I., Kotin, R.M., Derksen, T.A., Zabner, J., Ghodsi, A., and Chiorini, J.A. (2000) Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA, 97: 3428-3432.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3428-3432
    • Davidson, B.1    Stein, C.2    Heth, J.3    Martins, I.4    Kotin, R.M.5    Derksen, T.A.6    Zabner, J.7    Ghodsi, A.8    Chiorini, J.A.9
  • 27
    • 27144473384 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation
    • Denby, L., Nicklin, S.A., and Baker, A.H. (2005) Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation. Gene Ther., 12: 1534-1538.
    • (2005) Gene Ther. , vol.12 , pp. 1534-1538
    • Denby, L.1    Nicklin, S.A.2    Baker, A.H.3
  • 29
    • 5344229985 scopus 로고    scopus 로고
    • Anti-oxidative stress-associated genes in circulating progenitor cells: Evidence for enhanced resistance against oxidative stress
    • Dernbach, E., Urbich, C., Brandes, R.P., Hofmann, W.K., Zeiher, A.M., and Dimmeler, S. (2004) Anti-oxidative stress-associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress. Blood, 104: 3591-3597.
    • (2004) Blood , vol.104 , pp. 3591-3597
    • Dernbach, E.1    Urbich, C.2    Brandes, R.P.3    Hofmann, W.K.4    Zeiher, A.M.5    Dimmeler, S.6
  • 30
    • 0037090776 scopus 로고    scopus 로고
    • Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
    • Dor, Y., Djonov, V., Abramovitch, R., Itin, A., Fishman, G. I., Carmeliet, P., Goelman, G., and Keshet, E. (2002) Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J., 21: 1939-1947.
    • (2002) EMBO J. , vol.21 , pp. 1939-1947
    • Dor, Y.1    Djonov, V.2    Abramovitch, R.3    Itin, A.4    Fishman, G.I.5    Carmeliet, P.6    Goelman, G.7    Keshet, E.8
  • 32
    • 30744457050 scopus 로고    scopus 로고
    • New strategies for cardiovascular gene therapy: Regulatable pre-emptive expression of pro-angiogenic and antioxidant genes
    • Dulak, J., Zagorska, A., Wegiel, B., Loboda, A., and Jozkowicz, A. (2006) New strategies for cardiovascular gene therapy: regulatable pre-emptive expression of pro-angiogenic and antioxidant genes. Cell. Biochem. Biophys., 44: 31-42.
    • (2006) Cell. Biochem. Biophys. , vol.44 , pp. 31-42
    • Dulak, J.1    Zagorska, A.2    Wegiel, B.3    Loboda, A.4    Jozkowicz, A.5
  • 33
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004 - An overview
    • Edelstein, M.L., Abedi, M.R., Wixon, J., and Edelstein, R.M. (2004) Gene therapy clinical trials worldwide 1989-2004 - an overview. J. Gene Med., 6: 597-602.
    • (2004) J. Gene Med. , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 36
    • 0037159284 scopus 로고    scopus 로고
    • Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs
    • Emanueli, C., Salis, M.B., Pinna, A., Graiani, G., Manni, L., and Madeddu, P. (2002) Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs. Circulation, 106: 2257-2262.
    • (2002) Circulation , vol.106 , pp. 2257-2262
    • Emanueli, C.1    Salis, M.B.2    Pinna, A.3    Graiani, G.4    Manni, L.5    Madeddu, P.6
  • 39
    • 0345411588 scopus 로고    scopus 로고
    • Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV)
    • Erles, K., Sebokova, P., and Schlehofer, J. R. (1999) Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV). J. Med. Virol., 59: 406-411.
    • (1999) J. Med. Virol. , vol.59 , pp. 406-411
    • Erles, K.1    Sebokova, P.2    Schlehofer, J.R.3
  • 41
    • 0036137469 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for coronary artery disease
    • Freedman, S.B., and Isner, J.M. (2002) Therapeutic angiogenesis for coronary artery disease. Ann. Intern. Med., 1: 54-71.
    • (2002) Ann. Intern. Med. , vol.1 , pp. 54-71
    • Freedman, S.B.1    Isner, J.M.2
  • 42
    • 33644866801 scopus 로고    scopus 로고
    • Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction
    • Galasso, G., Schiekofer, S., Sato, K., Shibata, R., Handy, D.E., Ouchi, N., Leopold, J.A., Loscalzo, J., and Walsh, K. (2006) Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ. Res., 98: 254-261.
    • (2006) Circ. Res. , vol.98 , pp. 254-261
    • Galasso, G.1    Schiekofer, S.2    Sato, K.3    Shibata, R.4    Handy, D.E.5    Ouchi, N.6    Leopold, J.A.7    Loscalzo, J.8    Walsh, K.9
  • 45
    • 0029877965 scopus 로고    scopus 로고
    • Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
    • Giordano, F.J., Ping, P., McKirnan, M.D., Nozaki, S., DeMaria, A.N., Dillmann, W.H., Mathieu-Costello, O., and Hammond, H.K. (1996) Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart. Nat. Med., 2: 534-539.
    • (1996) Nat. Med. , vol.2 , pp. 534-539
    • Giordano, F.J.1    Ping, P.2    McKirnan, M.D.3    Nozaki, S.4    DeMaria, A.N.5    Dillmann, W.H.6    Mathieu-Costello, O.7    Hammond, H.K.8
  • 46
    • 0032870158 scopus 로고    scopus 로고
    • Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2
    • Girod, A., Ried, M., Wobus, C., Lahm, H., Leike, K., Kleinschmidt, J., Deleage, G., and Hallek, M. (1999) Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nat. Med., 5, 1052-1056.
    • (1999) Nat. Med. , vol.5 , pp. 1052-1056
    • Girod, A.1    Ried, M.2    Wobus, C.3    Lahm, H.4    Leike, K.5    Kleinschmidt, J.6    Deleage, G.7    Hallek, M.8
  • 47
    • 1542369977 scopus 로고    scopus 로고
    • From virus evolution to vector revolution: Use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
    • Grimm, D., and Kay, M.A. (2003) From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr. Gene Ther., 3: 281-304.
    • (2003) Curr. Gene Ther. , vol.3 , pp. 281-304
    • Grimm, D.1    Kay, M.A.2
  • 48
    • 0033544010 scopus 로고    scopus 로고
    • Progress in adeno-associated virus type 2 vector production: Promises and prospects for clinical use
    • Grimm, D., and Kleinschmidt, J.A. (1999) Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use. Hum. Gene Ther., 10: 2445-2450.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2445-2450
    • Grimm, D.1    Kleinschmidt, J.A.2
  • 49
    • 0032170672 scopus 로고    scopus 로고
    • Heart-specific targeting of betagalactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors
    • Griscelli, F., Gilardi-Hebenstreit, P., Hanania, N., Franz, W.M., Opolon, P., Perricaudet, M., and Ragot, T. (1998) Heart-specific targeting of betagalactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors. Hum. Gene Ther., 9: 1919-1928.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1919-1928
    • Griscelli, F.1    Gilardi-Hebenstreit, P.2    Hanania, N.3    Franz, W.M.4    Opolon, P.5    Perricaudet, M.6    Ragot, T.7
  • 52
    • 0034992340 scopus 로고    scopus 로고
    • Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors
    • Halbert, C. L., Allen, J. M., and Miller, A. D. (2001) Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors. J. Virol., 75: 6615-6624.
    • (2001) J. Virol. , vol.75 , pp. 6615-6624
    • Halbert, C.L.1    Allen, J.M.2    Miller, A.D.3
  • 54
    • 0037368410 scopus 로고    scopus 로고
    • Generation and characterization of chimeric recombinant AAV vectors
    • Hauck, B., Chen, L., and Xiao, W. (2003) Generation and characterization of chimeric recombinant AAV vectors. Mol. Ther., 7: 419-425.
    • (2003) Mol. Ther. , vol.7 , pp. 419-425
    • Hauck, B.1    Chen, L.2    Xiao, W.3
  • 56
    • 0033982580 scopus 로고    scopus 로고
    • Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion: Evidence for a dose-dependent effect
    • Hendel, R.C., Henry, T.D., Rocha-Singh, K., Isner, J.M., Kereiakes, D.J., Giordano, F.J., Simons, M., and Bonow, R.O. (2000) Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion: evidence for a dose-dependent effect. Circulation, 101: 118-121.
    • (2000) Circulation , vol.101 , pp. 118-121
    • Hendel, R.C.1    Henry, T.D.2    Rocha-Singh, K.3    Isner, J.M.4    Kereiakes, D.J.5    Giordano, F.J.6    Simons, M.7    Bonow, R.O.8
  • 58
    • 0034968125 scopus 로고    scopus 로고
    • Hybrid vectors based on adeno-associated vinis serotypes 2 and 5 for muscle-directed gene transfer
    • Hildinger, M., Auricchio, A., Gao, G., Wang, L., Chirmule, N., and Wilson, J.M. (2001) Hybrid vectors based on adeno-associated vinis serotypes 2 and 5 for muscle-directed gene transfer. J. Virol., 75: 6199-6203.
    • (2001) J. Virol. , vol.75 , pp. 6199-6203
    • Hildinger, M.1    Auricchio, A.2    Gao, G.3    Wang, L.4    Chirmule, N.5    Wilson, J.M.6
  • 59
    • 33745143956 scopus 로고    scopus 로고
    • Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8
    • Inagaki, K., Fuess, S., Storm, T.A., Gibson, G.A., Mctiernan, C.F., Kay, M.A., and Nakai, H. (2006) Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol. Ther., 14: 45-53.
    • (2006) Mol. Ther. , vol.14 , pp. 45-53
    • Inagaki, K.1    Fuess, S.2    Storm, T.A.3    Gibson, G.A.4    Mctiernan, C.F.5    Kay, M.A.6    Nakai, H.7
  • 60
    • 0035980172 scopus 로고    scopus 로고
    • Assessment of risks associated with cardiovascular gene therapy in human subjects
    • Isner, J.M., Vale, P.R., Symes, J.F., and Losordo, D.W. (2001) Assessment of risks associated with cardiovascular gene therapy in human subjects. Circ. Res., 89: 389-400.
    • (2001) Circ. Res. , vol.89 , pp. 389-400
    • Isner, J.M.1    Vale, P.R.2    Symes, J.F.3    Losordo, D.W.4
  • 62
    • 0035103833 scopus 로고    scopus 로고
    • Effects of in. vivo gene transfer of fibroblast growth factor-2 on cardiac function and collateral vessel formation in the microembolized rabbit heart
    • Iwatate, M., Miura, T., Ikeda, Y., Kawamura, S., Dairaku, Y., Okamura, T., Kimura, M., Yamaguchi, K., Ueno, H., and Matsuzaki, M. (2001) Effects of in. vivo gene transfer of fibroblast growth factor-2 on cardiac function and collateral vessel formation in the microembolized rabbit heart. Jpn. Circ. J, 65: 226-231.
    • (2001) Jpn. Circ. J , vol.65 , pp. 226-231
    • Iwatate, M.1    Miura, T.2    Ikeda, Y.3    Kawamura, S.4    Dairaku, Y.5    Okamura, T.6    Kimura, M.7    Yamaguchi, K.8    Ueno, H.9    Matsuzaki, M.10
  • 63
    • 24944534593 scopus 로고    scopus 로고
    • VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling
    • Kano, M.R., Morishita, Y., Iwata, C., Iwasaka, S., Watabe, T., Ouchi, Y., Miyazono, K., and Miyazawa, K. (2005) VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling. J. Cell Sci., 118: 3759-3768.
    • (2005) J. Cell Sci. , vol.118 , pp. 3759-3768
    • Kano, M.R.1    Morishita, Y.2    Iwata, C.3    Iwasaka, S.4    Watabe, T.5    Ouchi, Y.6    Miyazono, K.7    Miyazawa, K.8
  • 64
    • 20144386684 scopus 로고    scopus 로고
    • Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: The Euroinject One trial
    • Euroinject One Group
    • Kastrup, J., Jorgensen, E., Ruck, A., Tagil, K., Glogar, D., Ruzyllo, W., Botker, H.E., Dudek, D., Drvota, V., Hesse, B., Thuesen, L., Blomberg, P., Gyongyosi, M., and Sylven, C.; Euroinject One Group. (2005) Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial. J. Am. Coll. Cardiol., 45: 982-988.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 982-988
    • Kastrup, J.1    Jorgensen, E.2    Ruck, A.3    Tagil, K.4    Glogar, D.5    Ruzyllo, W.6    Botker, H.E.7    Dudek, D.8    Drvota, V.9    Hesse, B.10    Thuesen, L.11    Blomberg, P.12    Gyongyosi, M.13    Sylven, C.14
  • 65
    • 19444363187 scopus 로고    scopus 로고
    • Widespread and early myocardial gene expression by adeno-associated virus vector type 6 with a beta-actin hybrid promoter
    • Kawamoto, S., Shi, Q., Nitta, Y., Miyazaki, J., and Allen, M.D. (2005) Widespread and early myocardial gene expression by adeno-associated virus vector type 6 with a beta-actin hybrid promoter. Mol. Ther., 11: 980-985.
    • (2005) Mol. Ther. , vol.11 , pp. 980-985
    • Kawamoto, S.1    Shi, Q.2    Nitta, Y.3    Miyazaki, J.4    Allen, M.D.5
  • 66
    • 0041806502 scopus 로고    scopus 로고
    • Looking into the safety of AAV vectors
    • Kay, M.A., and Nakai, H. (2003) Looking into the safety of AAV vectors. Nature, 424: 251.
    • (2003) Nature , vol.424 , pp. 251
    • Kay, M.A.1    Nakai, H.2
  • 68
    • 11844288284 scopus 로고    scopus 로고
    • Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE)
    • Kingsman, S.M., Mitrophanous, K., and Olsen, J.C. (2005) Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE). Gene Ther., 12: 3-4.
    • (2005) Gene Ther. , vol.12 , pp. 3-4
    • Kingsman, S.M.1    Mitrophanous, K.2    Olsen, J.C.3
  • 69
    • 33745965951 scopus 로고    scopus 로고
    • Combination of in. vivo angiopoietin-1 gene transfer and autologous bone marrow cell implantation for functional therapeutic angiogenesis
    • Kobayashi, K., Kondo, T., Inoue, N., Aoki, M., Mizuno, M., Komori, K., Yoshida, J., and Murohara, T. (2006) Combination of in. vivo angiopoietin-1 gene transfer and autologous bone marrow cell implantation for functional therapeutic angiogenesis. Arterioscler. Thromb. Vasc. Biol., 26: 1465-1472.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1465-1472
    • Kobayashi, K.1    Kondo, T.2    Inoue, N.3    Aoki, M.4    Mizuno, M.5    Komori, K.6    Yoshida, J.7    Murohara, T.8
  • 75
    • 0034702905 scopus 로고    scopus 로고
    • VEGF gene delivery to myocardium: Deleterious effects of unregulated expression
    • Lee, R.J., Springer, M.L., Blanco-Bose, W.E., Shaw, R., Ursell, P.C., and Blau, H.M. (2000) VEGF gene delivery to myocardium: deleterious effects of unregulated expression. Circulation, 102: 898-901.
    • (2000) Circulation , vol.102 , pp. 898-901
    • Lee, R.J.1    Springer, M.L.2    Blanco-Bose, W.E.3    Shaw, R.4    Ursell, P.C.5    Blau, H.M.6
  • 77
    • 28844492583 scopus 로고    scopus 로고
    • Endothelial progenitor cell dysfunction in type 1 diabetes: Another consequence of oxidative stress?
    • Loomans, C.J., De Koning, E.J., Staal, F.J,. Rabelink, T.J., and Zonneveld, A.J. (2005) Endothelial progenitor cell dysfunction in type 1 diabetes: another consequence of oxidative stress?. Antioxid. Redox. Signal, 7: 1468-1475.
    • (2005) Antioxid. Redox. Signal , vol.7 , pp. 1468-1475
    • Loomans, C.J.1    De Koning, E.J.2    Staal, F.J.3    Rabelink, T.J.4    Zonneveld, A.J.5
  • 78
    • 2942572769 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease: Pan II: Cell-based therapies
    • Losordo, D.W., and Dimmeler, S. (2004) Therapeutic angiogenesis and vasculogenesis for ischemic disease: pan II: cell-based therapies. Circulation, 109: 2692-2697.
    • (2004) Circulation , vol.109 , pp. 2692-2697
    • Losordo, D.W.1    Dimmeler, S.2
  • 79
    • 33745123717 scopus 로고    scopus 로고
    • A constitutively active hypoxia-inducible factor-1alpha/VP16 hybrid factor activates expression of the human B-type natriuretic peptide gene
    • Luo, Y., Jiang, C., Belanger, A.J., Akita, G.Y., Wadsworth, S.C., Gregory, R.J., and Vincent, K.A. (2006) A constitutively active hypoxia-inducible factor-1alpha/VP16 hybrid factor activates expression of the human B-type natriuretic peptide gene. Mol. Pharmacol., 69: 1953-1962.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1953-1962
    • Luo, Y.1    Jiang, C.2    Belanger, A.J.3    Akita, G.Y.4    Wadsworth, S.C.5    Gregory, R.J.6    Vincent, K.A.7
  • 81
    • 10944269753 scopus 로고    scopus 로고
    • Integration of adeno-associated virus (AAV) and recombinant AAV vectors
    • McCarty, D.M., Young, S.M. Jr, and Samulski, R.J. (2004) Integration of adeno-associated virus (AAV) and recombinant AAV vectors. Annu. Rev. Genet., 38: 819-845.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 819-845
    • McCarty, D.M.1    Young Jr., S.M.2    Samulski, R.J.3
  • 82
    • 0035667112 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus vector-transduced vascular endothelial cells express the thrombomodulin transgene under the regulation of enhanced plasminogen activator inhibitor-1 promoter
    • Mimur, J., Muramatsu, S., Hakamada, Y., Mori, K., Kikuchi, J., Urabe, M., Madoiwa, S., Ozawa, K., and Sakata, Y. (2001) Recombinant adeno-associated virus vector-transduced vascular endothelial cells express the thrombomodulin transgene under the regulation of enhanced plasminogen activator inhibitor-1 promoter. Gene Ther., 8: 1690-1697.
    • (2001) Gene Ther. , vol.8 , pp. 1690-1697
    • Mimur, J.1    Muramatsu, S.2    Hakamada, Y.3    Mori, K.4    Kikuchi, J.5    Urabe, M.6    Madoiwa, S.7    Ozawa, K.8    Sakata, Y.9
  • 83
    • 0033978147 scopus 로고    scopus 로고
    • AAV vectors: Is clinical success on the horizon?
    • Monahan, P.E., and Samulski, R.J. (2000) AAV vectors: is clinical success on the horizon? Gene Ther., 7: 24-30.
    • (2000) Gene Ther. , vol.7 , pp. 24-30
    • Monahan, P.E.1    Samulski, R.J.2
  • 84
    • 0030972807 scopus 로고    scopus 로고
    • Transcriptional regulation by cyclic AMP
    • Montminy, M. (1997) Transcriptional regulation by cyclic AMP. Annu. Rev. BioChem., 66:807-822.
    • (1997) Annu. Rev. BioChem. , vol.66 , pp. 807-822
    • Montminy, M.1
  • 86
    • 3042841635 scopus 로고    scopus 로고
    • Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection
    • Morris, K.V., and Rossi, J.J. (2004) Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection. Curr. HIV. Res., 2: 185-191.
    • (2004) Curr. HIV. Res. , vol.2 , pp. 185-191
    • Morris, K.V.1    Rossi, J.J.2
  • 87
    • 0036726577 scopus 로고    scopus 로고
    • Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy
    • Nicklin, S.A., and Baker, A.H. (2002) Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy. Curr. Gene Ther., 2: 273-93.
    • (2002) Curr. Gene Ther. , vol.2 , pp. 273-293
    • Nicklin, S.A.1    Baker, A.H.2
  • 92
    • 31644436481 scopus 로고    scopus 로고
    • Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene delivery
    • Pachori, A.S., Melo, L.G., Zhang, L., Solomon, S.D., and Dzau, V.J. (2006) Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene delivery. J. Am. Coll. Cardiol., 47: 635-643.
    • (2006) J. Am. Coll. Cardiol. , vol.47 , pp. 635-643
    • Pachori, A.S.1    Melo, L.G.2    Zhang, L.3    Solomon, S.D.4    Dzau, V.J.5
  • 93
    • 0036828063 scopus 로고    scopus 로고
    • Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells
    • Pajusola, K., Gruchala, M., Joch, H., Luscher, T.F., Yla-Herttuala, S., and Bueler, H. (2002) Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells. J. Virol., 76: 11530-11540.
    • (2002) J. Virol. , vol.76 , pp. 11530-11540
    • Pajusola, K.1    Gruchala, M.2    Joch, H.3    Luscher, T.F.4    Yla-Herttuala, S.5    Bueler, H.6
  • 95
    • 12144276611 scopus 로고    scopus 로고
    • Ischaemic preconditioning protects against ischaemia/reperfusion injury: Emerging concepts
    • Pasupathy, S., and Homer-Vanniasinkam, S. (2005) Ischaemic preconditioning protects against ischaemia/reperfusion injury: emerging concepts. Eur. J. Vasc. Endovasc. Surg., 29: 106-15.
    • (2005) Eur. J. Vasc. Endovasc. Surg. , vol.29 , pp. 106-115
    • Pasupathy, S.1    Homer-Vanniasinkam, S.2
  • 97
    • 0037199399 scopus 로고    scopus 로고
    • Defining gene transfer before expecting gene therapy: Putting the horse before the cart
    • Pislaru, S., Janssens, S.P., Gersh, B.J., and Simari, R.D. (2002) Defining gene transfer before expecting gene therapy: putting the horse before the cart. Circulation, 106: 631-636.
    • (2002) Circulation , vol.106 , pp. 631-636
    • Pislaru, S.1    Janssens, S.P.2    Gersh, B.J.3    Simari, R.D.4
  • 98
    • 20444452567 scopus 로고    scopus 로고
    • Gene transfer for ischemic cardiovascular disease: Is this the end of the beginning or the beginning of the end?
    • Pislaru, S.V. and Simari, S.D. (2005) Gene transfer for ischemic cardiovascular disease: is this the end of the beginning or the beginning of the end? Nat. Clin. Pract. Cardiovasc. Med, 2:138-144
    • (2005) Nat. Clin. Pract. Cardiovasc. Med , vol.2 , pp. 138-144
    • Pislaru, S.V.1    Simari, S.D.2
  • 99
    • 33645409031 scopus 로고    scopus 로고
    • Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation
    • Post, M.J., Sato, K., Murakami, M., Bao, J., Tirziu, D., Pearlman, J.D., and Simons, M. (2006) Adenoviral PR39 improves blood flow and myocardial function in a pig model of chronic myocardial ischemia by enhancing collateral formation. Am. J. Physiol. Regul. Integr. Comp. Physiol., 290: R494-500.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.290
    • Post, M.J.1    Sato, K.2    Murakami, M.3    Bao, J.4    Tirziu, D.5    Pearlman, J.D.6    Simons, M.7
  • 100
    • 12344253201 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for critical limb ischemia: Design of the hepatocyte growth factor therapeutic angiogenesis clinical trial
    • Powell, R.J., Dormandy, J., Simons, M., Morishita, R., and Annex, B.H. (2004) Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial. Vasc. Med., 9: 193-198.
    • (2004) Vasc. Med. , vol.9 , pp. 193-198
    • Powell, R.J.1    Dormandy, J.2    Simons, M.3    Morishita, R.4    Annex, B.H.5
  • 101
    • 4444352441 scopus 로고    scopus 로고
    • Cross-dressing the virion: The transcapsidation of adeno-associated virus serotypes functionally defines subgroups
    • Rabinowitz, J.E., Bowles, D.E., Faust, S.M., Ledford, J.G., Cunningham, S.E., and Samulski, R.J. (2004) Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups. J. Virol., 78: 4421-4432.
    • (2004) J. Virol. , vol.78 , pp. 4421-4432
    • Rabinowitz, J.E.1    Bowles, D.E.2    Faust, S.M.3    Ledford, J.G.4    Cunningham, S.E.5    Samulski, R.J.6
  • 103
    • 4644285407 scopus 로고    scopus 로고
    • Sitespecific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors
    • Recchia, A., Perani, L., Sartori, D., Olgiati, C., and Mavilio, F. (2004) Sitespecific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors. Mol. Ther., 10: 660-670.
    • (2004) Mol. Ther. , vol.10 , pp. 660-670
    • Recchia, A.1    Perani, L.2    Sartori, D.3    Olgiati, C.4    Mavilio, F.5
  • 107
    • 33747584384 scopus 로고    scopus 로고
    • Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice
    • Riviere, C., Danos, O., and Douar, A.M. (2006) Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice. Gene Ther., 13: 1300-1308.
    • (2006) Gene Ther. , vol.13 , pp. 1300-1308
    • Riviere, C.1    Danos, O.2    Douar, A.M.3
  • 108
    • 0031984786 scopus 로고    scopus 로고
    • Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes Rother than AAV type 2
    • Rutledge E, Halbert C, and Russell D. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes Rother than AAV type 2. J. Virol., 1998; 72(1): 309-319.
    • (1998) J. Virol. , vol.72 , Issue.1 , pp. 309-319
    • Rutledge, E.1    Halbert, C.2    Russell, D.3
  • 109
    • 0037829897 scopus 로고    scopus 로고
    • Lentivirus vector-mediated gene transfer to cardiomyocytes
    • Sakoda, T., Kasahara, N., and Kedes, L. (2003) Lentivirus vector-mediated gene transfer to cardiomyocytes. Methods. Mol. Biol., 219: 53-70.
    • (2003) Methods. Mol. Biol. , vol.219 , pp. 53-70
    • Sakoda, T.1    Kasahara, N.2    Kedes, L.3
  • 110
    • 33749074728 scopus 로고    scopus 로고
    • Beta-adrenoceptor blockade markedly attenuates transgene expression from cytomegalovirus promoters within the cardiovascular system
    • Salem, H.K., Ranjzad, P., Driessen, A., Appleby, C.E., Heagerty, A.M., and Kingston, P.A. (2006) Beta-adrenoceptor blockade markedly attenuates transgene expression from cytomegalovirus promoters within the cardiovascular system. Arterioscler. Thromb. Vasc. Biol., 26: 2267-2274.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 2267-2274
    • Salem, H.K.1    Ranjzad, P.2    Driessen, A.3    Appleby, C.E.4    Heagerty, A.M.5    Kingston, P.A.6
  • 111
    • 33644618775 scopus 로고    scopus 로고
    • Bone-marrow-derived progenitor cell therapy in need of proof of concept: Design of the REPAIR-AMI trial
    • Schachinger, V., Tonn, T., Dimmeler, S., and Zeiher, A.M. (2006) Bone-marrow-derived progenitor cell therapy in need of proof of concept: design of the REPAIR-AMI trial. Nat. Clin. Pract. Cardiovasc. Med., 3: S23-8.
    • (2006) Nat. Clin. Pract. Cardiovasc. Med. , vol.3
    • Schachinger, V.1    Tonn, T.2    Dimmeler, S.3    Zeiher, A.M.4
  • 112
    • 0026646222 scopus 로고
    • Basic fibroblast growth factor modulates the mitogenic potency of the platelet-derived growth factor (PDGF) isoforms by specific upregulation of the PDGF alpha receptor in vascular smooth muscle cells
    • Schollmann, C., Grugel, R., Tatje, D., Hoppe, J., Folkman, J., Marme, D., and Weich, H.A. (1992) Basic fibroblast growth factor modulates the mitogenic potency of the platelet-derived growth factor (PDGF) isoforms by specific upregulation of the PDGF alpha receptor in vascular smooth muscle cells. J. Biol. Chem., 267: 18032-18039.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18032-18039
    • Schollmann, C.1    Grugel, R.2    Tatje, D.3    Hoppe, J.4    Folkman, J.5    Marme, D.6    Weich, H.A.7
  • 114
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • Schroder, A.R., Shinn, P., Chen, H., Berry, C., Ecker, J.R., and Bushman, F. (2002) HIV-1 integration in the human genome favors active genes and local hotspots. Cell, 110: 521-529.
    • (2002) Cell , vol.110 , pp. 521-529
    • Schroder, A.R.1    Shinn, P.2    Chen, H.3    Berry, C.4    Ecker, J.R.5    Bushman, F.6
  • 115
    • 0033520043 scopus 로고    scopus 로고
    • Interindividual heterogeneity in the hypoxic regulation of VEGF: Significance for the development of the coronary artery collateral circulation
    • Schultz, A., Lavie, L., Hochberg, I., Beyar, R., Stone, T., Skorecki, K., Lavie, P., Roguin, A., and Levy, A.P. (1999) Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation. Circulation, 100: 547-52.
    • (1999) Circulation , vol.100 , pp. 547-552
    • Schultz, A.1    Lavie, L.2    Hochberg, I.3    Beyar, R.4    Stone, T.5    Skorecki, K.6    Lavie, P.7    Roguin, A.8    Levy, A.P.9
  • 116
    • 30744440945 scopus 로고    scopus 로고
    • Adeno-associated virus types 5 and 6 use distinct receptors for cell entry
    • Seiler, M.P., Miller, A.D., Zabner, J., and Halbert, C.L. (2006) Adeno-associated virus types 5 and 6 use distinct receptors for cell entry. Hum. Gene Ther., 17: 10-19.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 10-19
    • Seiler, M.P.1    Miller, A.D.2    Zabner, J.3    Halbert, C.L.4
  • 117
    • 33645456779 scopus 로고    scopus 로고
    • Insertional mutagenesis at positions 520 and 584 of adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors with eliminated heparin- binding ability and introduced novel tropism
    • Shi, X., Fang, G., and Shi, W. (2006) Insertional mutagenesis at positions 520 and 584 of adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors with eliminated heparin- binding ability and introduced novel tropism. Hum. Gene Ther., 17: 353-361.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 353-361
    • Shi, X.1    Fang, G.2    Shi, W.3
  • 120
    • 0036275028 scopus 로고    scopus 로고
    • Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat
    • Shyu, K.G., Wang, M.T., Wang, B.W., Chang, C.C., Leu, J.G., Kuan, P., and Chang, H. (2002) Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc. Res., 54: 576-583.
    • (2002) Cardiovasc. Res. , vol.54 , pp. 576-583
    • Shyu, K.G.1    Wang, M.T.2    Wang, B.W.3    Chang, C.C.4    Leu, J.G.5    Kuan, P.6    Chang, H.7
  • 121
    • 33646760315 scopus 로고    scopus 로고
    • Mosaic vectors comprised of modified AAV1 capsid proteins for efficient vector purification and targeting to vascular endothelial cells
    • Stachler, M.D., and Bartlett, J.S. (2006) Mosaic vectors comprised of modified AAV1 capsid proteins for efficient vector purification and targeting to vascular endothelial cells. Gene Ther., 13: 926-931.
    • (2006) Gene Ther. , vol.13 , pp. 926-931
    • Stachler, M.D.1    Bartlett, J.S.2
  • 123
    • 33745206550 scopus 로고    scopus 로고
    • Stem cell therapy for ischemic heart disease: Beginning or end of the road?
    • Stamm, C., Liebold, A., Steinhoff, G., and Strunk, D. (2006) Stem cell therapy for ischemic heart disease: beginning or end of the road? Cell. Transplant., 15: S47-56.
    • (2006) Cell. Transplant. , vol.15
    • Stamm, C.1    Liebold, A.2    Steinhoff, G.3    Strunk, D.4
  • 124
    • 0020049695 scopus 로고
    • Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by rat platelet-associated substance(s)
    • Strain, A.J., McGowan, J.A., and Bucher, N.L. (1982) Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by rat platelet-associated substance(s). In Vitro, 18: 108-116.
    • (1982) In Vitro , vol.18 , pp. 108-116
    • Strain, A.J.1    McGowan, J.A.2    Bucher, N.L.3
  • 125
    • 9244261579 scopus 로고    scopus 로고
    • Adeno-associated vital vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts
    • Su, H., Joho, S., Huang, Y., Barcena, A., Arakawa-Hoyt, J., Grossman, W., and Kan, Y.W. (2004) Adeno-associated vital vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts. Proc. Natl. Acad. Sci. USA, 101: 16280-16285.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16280-16285
    • Su, H.1    Joho, S.2    Huang, Y.3    Barcena, A.4    Arakawa-Hoyt, J.5    Grossman, W.6    Kan, Y.W.7
  • 126
    • 33750025357 scopus 로고    scopus 로고
    • AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect
    • Su, H., Huang, Y., Takagawa, J., Barcena, A., Arakawa-Hoyt, J., Ye, J., Grossman, W., and Kan, Y.W. (2006) AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect. Gene Ther., 13: 1495-1502.
    • (2006) Gene Ther. , vol.13 , pp. 1495-1502
    • Su, H.1    Huang, Y.2    Takagawa, J.3    Barcena, A.4    Arakawa-Hoyt, J.5    Ye, J.6    Grossman, W.7    Kan, Y.W.8
  • 127
    • 0029958320 scopus 로고    scopus 로고
    • Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
    • Takeshita, S., Tsurumi, Y., Couffinahl, T., Sahara, T., Banters, C., Symes, J., Ferrara, N., and Isner, J.M. (1996) Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. Lab. Invest., 75: 487-501.
    • (1996) Lab. Invest. , vol.75 , pp. 487-501
    • Takeshita, S.1    Tsurumi, Y.2    Couffinahl, T.3    Sahara, T.4    Banters, C.5    Symes, J.6    Ferrara, N.7    Isner, J.M.8
  • 128
    • 27744505661 scopus 로고    scopus 로고
    • Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector
    • Tang, Y.L., Tang, Y., Zhang, Y.C., Qian, K., Shen, L., and Phillips, M.I. (2005) Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector. J. Am. Coll. Cardiol., 46: 1339-1350.
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1339-1350
    • Tang, Y.L.1    Tang, Y.2    Zhang, Y.C.3    Qian, K.4    Shen, L.5    Phillips, M.I.6
  • 129
    • 1642501642 scopus 로고    scopus 로고
    • Protection from ischemic heart injury by a vigilant heme oxygenase-1 plasmid system
    • Tang, Y.L., Tang, Y., Zhang, Y.C., Qian, K., Shen, L., and Phillips, M.I. (2004) Protection from ischemic heart injury by a vigilant heme oxygenase-1 plasmid system. Hypertension, 43:746-751.
    • (2004) Hypertension , vol.43 , pp. 746-751
    • Tang, Y.L.1    Tang, Y.2    Zhang, Y.C.3    Qian, K.4    Shen, L.5    Phillips, M.I.6
  • 130
    • 17744388581 scopus 로고    scopus 로고
    • Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMG-CoA reductase inhibitors
    • Urbich, C., and Dimmeler, S. (2005) Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMG-CoA reductase inhibitors. Kidney Int., 67: 1672-1676.
    • (2005) Kidney Int. , vol.67 , pp. 1672-1676
    • Urbich, C.1    Dimmeler, S.2
  • 131
    • 28544431828 scopus 로고    scopus 로고
    • Ischemic preconditioning by unstable angina reduces the release of CK-MB following CABG and stimulates left ventricular HSP-72 protein expression
    • Vahlhaus, C., Neumann, J., Luss, H., Wenzelburger, F., Tjan, T.D., Hammel, D., Scheid, H.H., Schmitz, W., Breithardt, G., and Wichter, T. (2005) Ischemic preconditioning by unstable angina reduces the release of CK-MB following CABG and stimulates left ventricular HSP-72 protein expression. J. Card. Surg., 20: 412-419.
    • (2005) J. Card. Surg. , vol.20 , pp. 412-419
    • Vahlhaus, C.1    Neumann, J.2    Luss, H.3    Wenzelburger, F.4    Tjan, T.D.5    Hammel, D.6    Scheid, H.H.7    Schmitz, W.8    Breithardt, G.9    Wichter, T.10
  • 132
    • 17644433975 scopus 로고    scopus 로고
    • Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    • Vasa, M., Fichtlscherer, S., Aicher, A., Adler, K., Urbich, C., Martin, H., Zeiher, A.M., and Dimmeler, S. (2001) Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res., 89: E1-7.
    • (2001) Circ. Res. , vol.89
    • Vasa, M.1    Fichtlscherer, S.2    Aicher, A.3    Adler, K.4    Urbich, C.5    Martin, H.6    Zeiher, A.M.7    Dimmeler, S.8
  • 133
    • 0042885512 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: A comparative study with adenovirus vectors
    • Vassalli, G., Bueler, H., Dudler, J., von Segesser, L.K., and Kappenberger, L. (2003) Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors. Int. J. Cardiol., 90: 229-238.
    • (2003) Int. J. Cardiol. , vol.90 , pp. 229-238
    • Vassalli, G.1    Bueler, H.2    Dudler, J.3    von Segesser, L.K.4    Kappenberger, L.5
  • 135
    • 22244459917 scopus 로고    scopus 로고
    • Gene therapy: Twenty-first century medicine
    • Verma, I.M. and Weitzman, M.D. (2005) Gene therapy: twenty-first century medicine. Annu. Rev. BioChem., 74: 711-738.
    • (2005) Annu. Rev. BioChem. , vol.74 , pp. 711-738
    • Verma, I.M.1    Weitzman, M.D.2
  • 136
    • 0034739533 scopus 로고    scopus 로고
    • Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor
    • Vincent, K.A., Shyu, K.G., Luo, Y., Magner, M., Tio, R.A., Jiang, C., Goldberg, M.A., Akita, G.Y., Gregory, R.J., and Isner, J.M. (2000) Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor. Circulation, 102: 2255-2261.
    • (2000) Circulation , vol.102 , pp. 2255-2261
    • Vincent, K.A.1    Shyu, K.G.2    Luo, Y.3    Magner, M.4    Tio, R.A.5    Jiang, C.6    Goldberg, M.A.7    Akita, G.Y.8    Gregory, R.J.9    Isner, J.M.10
  • 139
    • 33745181228 scopus 로고    scopus 로고
    • Potential therapeutic gene for the treatment of ischemic disease: Ad2/hypoxia-inducible factor-1alpha (HIF-1)/VP16 enhances B-type natriuretic peptide gene expression via a HIF-1-responsive element
    • Wilhide, M.E., and Jones, W.K. (2006) Potential therapeutic gene for the treatment of ischemic disease: Ad2/hypoxia-inducible factor-1alpha (HIF-1)/VP16 enhances B-type natriuretic peptide gene expression via a HIF-1-responsive element. Mol. Pharmacol., 69: 1773-1778.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1773-1778
    • Wilhide, M.E.1    Jones, W.K.2
  • 140
    • 11344252479 scopus 로고    scopus 로고
    • Harnessing HIV for therapy, basic research and biotechnology
    • Wiznerowicz, M., and Trono, D. (2005) Harnessing HIV for therapy, basic research and biotechnology. Trends Biotechnol., 23: 42-47.
    • (2005) Trends Biotechnol. , vol.23 , pp. 42-47
    • Wiznerowicz, M.1    Trono, D.2
  • 142
    • 33746874152 scopus 로고    scopus 로고
    • Adeno-associated virus serotypes: Vector toolkit for human gene therapy
    • Wu, Z., Asokan, A., and Samulski, R.J. (2006) Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol. Ther., 14: 316-327.
    • (2006) Mol. Ther. , vol.14 , pp. 316-327
    • Wu, Z.1    Asokan, A.2    Samulski, R.J.3
  • 144
    • 0242600657 scopus 로고    scopus 로고
    • Genetic redox preconditioning differentially modulates AP-1 and NF kappa B responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis
    • Yang, J., Marden, J.J., Fan, C., Sanlioglu, S., Weiss, R.M., Ritchie, T.C., Davisson, R.L., and Engelhardt, J.F. (2003) Genetic redox preconditioning differentially modulates AP-1 and NF kappa B responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis. Mol. Ther., 7: 341-353.
    • (2003) Mol. Ther. , vol.7 , pp. 341-353
    • Yang, J.1    Marden, J.J.2    Fan, C.3    Sanlioglu, S.4    Weiss, R.M.5    Ritchie, T.C.6    Davisson, R.L.7    Engelhardt, J.F.8
  • 145
    • 0037968240 scopus 로고    scopus 로고
    • Gene transfer as a tool to induce therapeutic vascular growth
    • Yla-Herttuala, S., and Alitalo K. (2003) Gene transfer as a tool to induce therapeutic vascular growth. Nat. Med., 9: 694-701.
    • (2003) Nat. Med. , vol.9 , pp. 694-701
    • Yla-Herttuala, S.1    Alitalo, K.2
  • 146
    • 18844417604 scopus 로고    scopus 로고
    • Gene therapy for ischemic cardiovascular diseases: Some lessons learned from the first clinical trials
    • Yla-Herttuala, S., Markkanen, J.E., and Rissanen, T.T. (2004) Gene therapy for ischemic cardiovascular diseases: some lessons learned from the first clinical trials. Trends Cardiovasc. Med., 14: 295-300.
    • (2004) Trends Cardiovasc. Med. , vol.14 , pp. 295-300
    • Yla-Herttuala, S.1    Markkanen, J.E.2    Rissanen, T.T.3
  • 147
    • 0035957249 scopus 로고    scopus 로고
    • H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene
    • Yoshida, T., Maulik, N., Ho, Y.S., Alam, J., and Das, D.K. (2001) H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene. Circulation, 103: 1695-1701.
    • (2001) Circulation , vol.103 , pp. 1695-1701
    • Yoshida, T.1    Maulik, N.2    Ho, Y.S.3    Alam, J.4    Das, D.K.5
  • 148
    • 0034026085 scopus 로고    scopus 로고
    • Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer
    • Zabner, J., Seiler, M., Walters, R., Kotin, R.M., Fulgeras, W., Davidson, B.L., and Chiorini, J.A. (2000) Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. J. Virol., 74: 3852-3858.
    • (2000) J. Virol. , vol.74 , pp. 3852-3858
    • Zabner, J.1    Seiler, M.2    Walters, R.3    Kotin, R.M.4    Fulgeras, W.5    Davidson, B.L.6    Chiorini, J.A.7
  • 149
    • 4644275138 scopus 로고    scopus 로고
    • HIF-1: The knowns and unknowns of hypoxia sensing
    • Zagorska, A., and Dulak, J. (2004) HIF-1: the knowns and unknowns of hypoxia sensing. Acta. Biochim. Pol., 51: 563-585.
    • (2004) Acta. Biochim. Pol. , vol.51 , pp. 563-585
    • Zagorska, A.1    Dulak, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.