H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart

Circulation Research

Volumn 98, Issue 2, 2006, Pages 280-288

  Depre, Christophe ^a   Wang, Li ^a   Sui, Xiangzhen ^a   Qiu, Hongyu ^a   Hong, Chull ^a   Hedhli, Nadia ^a   Ginion, Audrey ^b   Shah, Amy ^a   Pelat, Michel ^a   Bertrand, Luc ^b   Wagner, Thomas ^c   Gaussin, Vinciane ^a   Vatner, Stephen F ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

^c GREENVILLE HOSPITAL SYSTEM   (United States)

Author keywords

Akt; AMPK; Apoptosis; Cell survival; Ischemia

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE 3BETA; HEAT SHOCK PROTEIN 22; HEAT SHOCK PROTEIN 70; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE 3BETA; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG; 5' AMP ACTIVATED PROTEIN KINASE; 5'-AMP-ACTIVATED PROTEIN KINASE; HEAT SHOCK PROTEIN 20; HSPB8 PROTEIN, MOUSE; MULTIENZYME COMPLEX; MUSCLE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; GENE SWITCHING; GLUCOSE UTILIZATION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISCHEMIC HEART DISEASE; ISCHEMIC PRECONDITIONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; APOPTOSIS; CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CYTOLOGY; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; HSP20 HEAT-SHOCK PROTEINS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MICE; MICE, TRANSGENIC; MULTIENZYME COMPLEXES; MUSCLE PROTEINS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 33644862630     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000201284.45482.e8     Document Type: Article

References (34)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.
2. Depre C, Hase M, Gaussin V, Zajac A, Wang L, Hittinger L, Ghaleh B, Yu X, Kudej RK, Wagner T, Sadoshima J, Vatner SF. H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res. 2002;91:1007-1014.
3. Depre C, Tomlinson JE, Kudej RK, Gaussin V, Thompson E, Kim SJ, Vatner DE, Topper JN, Vatner SF. Gene program for cardiac cell survival induced by transient ischemia in conscious pig. Proc Natl Acad Sci U S A. 2001;98:9336-9341.
4. Depre C, Kim S-J, John AS, Hong Huang Y, Rimoldi OE, Pepper JR, Dreyfus GD, Gaussin V, Pennell DJ, Vatner DE, Camici PG, Vatner SF. Program of cell survival underlying human and experimental hibernating myocardium. Circ Res. 2004;95:433-440.
5. Cantley L. The phosphoinositide 3-kinase pathway. Science. 2002;296:1655-1657.
6. Wang L, Zajac A, Hedhli N, Depre C. Increased expression of H11 kinase stimulates glycogen synthesis in the heart. Mol Cell Biochem. 2004;265:71-78.
7. Depre C, Vanoverschelde J, Taegtmeyer H. Glucose for the heart. Circulation. 1999;99:578-588.
8. Russell RR, III, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest. 2004;114:495-503.
9. Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 2004;18:1926-1945.
10. Salt I, Celler J, Hawley S, Prescott A, Woods A, Carling D, Hardie D. AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the a2 isoform. Biochem J. 1998;334:177-187.
11. Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res. 2004;94:884-891.
12. Ping P, Song C, Zhang J, Guo Y, Cao X, Li RCX, Wu W, Vondriska TM, Pass JM, Tang X-L, Pierce WM, Bolli R. Formation of protein kinase C epsilon-Lck signaling modules confers cardioprotection. J Clin Invest. 2002;109:499-507.
13. Depre C, Wang L, Tomlinson J, Gaussin V, Abdellatif M, Topper J, Vatner S. Characterization of pDJA1, a cardiac-specific chaperone found by genomic profiling of the post-ischemic swine heart. Cardiovasc Res. 2003;58:126-135.
14. Marsin A, Bertrand L, Rider M, Deprez J, Beauloye C, Vincent M, Van den Berghe G, Carling D, Hue L. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischemia. Curr Biol. 2000;10:1247-1255.
15. Depre C, Rider MH, Veitch K, Hue L. Role of fructose 2,6-bisphosphate in the control of heart glycolysis. J Biol Chem. 1993;268:13274-13279.
16. Hase M, Depre C, Vatner S, Sadoshima J. H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes. Biochem J. 2005;388:475-483.
17. Kim H-S, Skurk C, Maatz H, Shiojima I, Ivashchenko Y, Yoon S-W, Park Y-B, Walsh K. Akt/FOXO3a signaling modulates the endothelial stress response through regulation of heat shock protein 70 expression. FASEB J. 2005;19:1042-1044.
18. Knowlton AA, Grenier M, Kirchhoff SR, Salfity M. Phosphorylation at tyrosine-524 influences nuclear accumulation of HSP72 with heat stress. Am J Physiol Heart Circ Physiol. 2000;278:H2143-H2149.
19. Tong H, Chen W, Steenbergen C, Murphy E. Ischemic preconditioning activates phosphatidylinositol 3-kinase upstream of protein kinase C. Circ Res. 2000;87:309-315.
20. Bolli R. Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol. 2001;33:1897-1918.
21. Smith C, Yu Y, Kulka M, Aurelian L. A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of Herpes Simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells. J Biol Chem. 2000;275:25690-25699.
22. Lee M, Hwang J-T, Lee H-J, Jung S-N, Kang I, Chi S-G, Kim S-S, Ha J. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 Cells. J Biol Chem. 2003;278:39653-39661.
23. Kim C-H, Cho Y-S, Chun Y-S, Park J-W, Kim M-S. Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway. Circ Res. 2002;90:25-33.
24. Semenza G. HIF-1, O2 and the 3 PHDs. How animal cells signal hypoxia to the nucleus. Cell. 2001;107:1-4.
25. Matsui T, Li L, Wu JC, Cook SA, Nagoshi T, Picard MH, Liao R, Rosenzweig A. Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem. 2002;277:22896-22901.
26. Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P, Rosen N. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function. J Biol Chem. 2002;277:39858-39866.
27. Zhang J, Baines CP, Zong C, Cardwell EM, Wang G, Vondriska TM, Ping P. Functional proteomic analysis of a three-tier PKC epsilon-Akt-eNOS signaling module in cardiac protection. Am J Physiol Heart Circ Physiol. 2005;288:H954-H961.
28. Nishino Y, Miura T, Miki T, Sakamoto J, Nakamura Y, Ikeda Y, Kobayashi H, Shimamoto K. Ischemic preconditioning activates AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection. Cardiovasc Res. 2004;61:610-619.
29. Jung F, Palmer LA, Zhou N, Johns RA. Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes. Circ Res. 2000;86:319-325.
30. Zhou J, Brune B. NO and transcriptional regulation: from signaling to death. Toxicology. 2005;208:223-233.
31. Balafanova Z, Bolli R, Zhang J, Zheng Y, Pass JM, Bhatnagar A, Tang X-L, Wang O, Cardwell E, Ping P. Nitric oxide (NO) induces nitration of protein kinase C epsilon, facilitating PKC epsilon translocation via enhanced PKC epsilon -RACK2 interactions. J Biol Chem. 2002;277:15021-15027.
32. Nolan S, Mannisi J, Bush D, Healy B, Weisman H. Increased afterload aggravates infarct expansion after acute myocardial infarction. J Am Coll Cardiol. 1988;12:1318-1325.
33. Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, Anversa P. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest. 1997;100:1991-1999.
34. Morrow G, Samson M, Michaud S, Tanguay RM. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J. 2004;18:598-599.