Heart-specific targeting of β-galactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors

Human Gene Therapy

Volumn 9, Issue 13, 1998, Pages 1919-1928

  Griscelli, Frank ^a   Gilardi Hebenstreit, Pascale ^b   Hanania, Nicole ^a   Franz, Wolfgang Mickael ^c   Opolon, Paule ^a   Perricaudet, Michel ^a   Ragot, Thierry ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DYSTROPHIN; MYOSIN LIGHT CHAIN; REPETITIVE DNA;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CLONING VECTOR; EMBRYO; GENE TARGETING; GENE TRANSFER; GENETIC CONSERVATION; HEART MUSCLE; HEART VENTRICLE; NONHUMAN; PROMOTER REGION; REPORTER GENE; SKELETAL MUSCLE; TARGET ORGAN;

EID: 0032170672     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.13-1919     Document Type: Article

References (8)

1. BARR, E., CARROLL, J., and KALYNYCH, A.M. (1994). Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther. 1, 51-58.
2. BESSEREAU, J.L., STRATFORD-PERRICAUDET, L.D., PIETTE, J., LE POUPON, C., and CHANGEUX, J.P. (1994). In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus. Proc. Natl. Acad. Sci. U.S.A. 91, 1304-1308.
3. BRENT, A.F., MAZUR, W., GESKE, R.S., and BOLLI, R. (1994). Direct in vivo gene transfer into porcine myocardium using replication deficient adenoviral vectors. Circulation 90, 2414-2424.
4. CORDIER, L., DUFFOUR, M.T., SABOURIN, J.C., LEE, M.G., CABANNES, J., RAGOT, T., PERRICAUDET, M., and HADDADA, H. (1995). Complete recovery of mice from a pre-established tumor by direct intratumoral delivery of an adenovirus vector harboring the murine IL-2 gene. Gene Ther. 2, 16-21.
5. DEDIEU, J.F., VIGNE, E., TORRENT, C., JULLIEN, C., MAHFOUZ, I., CAILLAUD, J.M., ORSINI, C., GUILLAUME, J.M., OPOLON, P., DELAERE, P., PERRICAUDET, M., and YEH, P. (1997). Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J. Virol. 71, 4626-4637.
6. FRANZ, W.M., BREVES, D., KLINGEL, K., BREM, G., HOFSCHNEIDER, P.H., and KANDOLF, R. (1993). Heart-specific targeting of firefly luciferase by the myosin light chain-2 promoter and developmental regulation in transgenic mice. Circ. Res. 73, 629-638.
7. FRANZ, W.M., ROTHMANN, T., FREY, N., and KATUS, H.A. (1997). Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters. Cardiovasc. Res. 35, 560-566.
8. ZHU, H., GARCIA, A.V., ROSS, R.S., EVANS, S.M., and CHIEN, K.R., (1991). A conserved 28-based pair element (HF-1) in the rat cardiac myosin light chain-2 gene confers cardiac-specific and α-adrenergic inducible expression in cultured neonatal rat myocardial cells. Mol. Cell Biol. 11, 2273-2281.