-
1
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Scandinavian Simvastatin Survival Study Group
-
Scandinavian Simvastatin Survival Study Group (1994) Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344: 1383-1389
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
2
-
-
0028123099
-
A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease
-
Benestent Study Group
-
Serruys PW et al. (1994) A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group. N Engl J Med 331: 489-495
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 489-495
-
-
Serruys, P.W.1
-
3
-
-
0027934377
-
A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease
-
Stent Restenosis Study Investigators
-
Fischman DL et al. (1994) A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. Stent Restenosis Study Investigators. N Engl J Med 331: 496-501
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 496-501
-
-
Fischman, D.L.1
-
4
-
-
0035980172
-
Assessment of risks associated with cardiovascular gene therapy in human subjects
-
Isner JM et al. (2001) Assessment of risks associated with cardiovascular gene therapy in human subjects. Circ Res 89: 389-400
-
(2001)
Circ. Res.
, vol.89
, pp. 389-400
-
-
Isner, J.M.1
-
5
-
-
0024392603
-
Recombinant gene expression in vivo within endothelial cells of the arterial wall
-
Nabel EG et al. (1989) Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science 244: 1342-1344
-
(1989)
Science
, vol.244
, pp. 1342-1344
-
-
Nabel, E.G.1
-
6
-
-
0024356590
-
Implantation of vascular grafts lined with genetically modified endothelial cells
-
Wilson JM et al. (1989) Implantation of vascular grafts lined with genetically modified endothelial cells. Science 244: 1344-1346
-
(1989)
Science
, vol.244
, pp. 1344-1346
-
-
Wilson, J.M.1
-
7
-
-
0030035247
-
Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries
-
Simari R et al. (1996) Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. J Clin Invest 98: 225-235
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 225-235
-
-
Simari, R.1
-
8
-
-
0026709283
-
Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor
-
Yanagisawa-Miwa A et al. (1992) Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor. Science 257: 1401-1403
-
(1992)
Science
, vol.257
, pp. 1401-1403
-
-
Yanagisawa-Miwa, A.1
-
9
-
-
0035313488
-
FGF and VEGF function in angiogenesis: Signalling pathways, biological responses and therapeutic inhibition
-
Cross MJ and Claesson-Welsh L (2001) FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 22: 201-207
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 201-207
-
-
Cross, M.J.1
Claesson-Welsh, L.2
-
10
-
-
0030453791
-
Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion
-
Tsurumi Y et al. (1996) Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. Circulation 94: 3281-3290
-
(1996)
Circulation
, vol.94
, pp. 3281-3290
-
-
Tsurumi, Y.1
-
11
-
-
15844420661
-
165 in patient with ischaemic limb
-
165 in patient with ischaemic limb. Lancet 348: 370-374
-
(1996)
Lancet
, vol.348
, pp. 370-374
-
-
Isner, J.M.1
-
12
-
-
0032583951
-
165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
-
165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 97: 1114-1123
-
(1998)
Circulation
, vol.97
, pp. 1114-1123
-
-
Baumgartner, I.1
-
13
-
-
0034612203
-
Lower-extremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor
-
Baumgartner I et al. (2000) Lower-extremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor. Ann Intern Med 132: 880-884
-
(2000)
Ann. Intern. Med.
, vol.132
, pp. 880-884
-
-
Baumgartner, I.1
-
14
-
-
0031797530
-
Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results
-
Isner JM et al. (1998) Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results. J Vasc Surg 28: 964-973
-
(1998)
J. Vasc. Surg.
, vol.28
, pp. 964-973
-
-
Isner, J.M.1
-
15
-
-
0037313811
-
Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia
-
Shyu KG et al. (2003) Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia. Am J Med 114: 85-92
-
(2003)
Am. J. Med.
, vol.114
, pp. 85-92
-
-
Shyu, K.G.1
-
16
-
-
0036665610
-
Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: A randomized, placebo-controlled, double-blinded phase II study
-
Makinen K et al. (2002) Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study. Mol Ther 6: 127-133
-
(2002)
Mol. Ther.
, vol.6
, pp. 127-133
-
-
Makinen, K.1
-
17
-
-
0036710990
-
Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication
-
Rajagopalan S et al. (2002) Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication. Am J Cardiol 90: 512-516
-
(2002)
Am. J. Cardiol.
, vol.90
, pp. 512-516
-
-
Rajagopalan, S.1
-
18
-
-
0142023866
-
Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
-
Rajagopalan S et al. (2003) Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 108: 1933-1938
-
(2003)
Circulation
, vol.108
, pp. 1933-1938
-
-
Rajagopalan, S.1
-
19
-
-
19044389402
-
Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: Preliminary results of a phase I trial
-
Comerota AJ et al. (2002) Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial. J Vasc Surg 35: 930-936
-
(2002)
J. Vasc. Surg.
, vol.35
, pp. 930-936
-
-
Comerota, A.J.1
-
20
-
-
3543025721
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
-
Morishita R et al. (2004) Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension 44: 203-209
-
(2004)
Hypertension
, vol.44
, pp. 203-209
-
-
Morishita, R.1
-
21
-
-
5444253160
-
Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial disease
-
Rajagopalan S et al. (2004) Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial disease. Hum Gene Ther 15: 619-24
-
(2004)
Hum. Gene Ther.
, vol.15
, pp. 619-624
-
-
Rajagopalan, S.1
-
22
-
-
17344371184
-
Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia
-
Laitinen M et al. (1998) Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. Hum Gene Ther 9: 1481-1486
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 1481-1486
-
-
Laitinen, M.1
-
23
-
-
0036376677
-
Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA
-
Freedman SB et al. (2002) Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA. Hum Gene Ther 13: 1595-1603
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 1595-1603
-
-
Freedman, S.B.1
-
24
-
-
0032578961
-
165 as sole therapy for myocardial ischemia
-
165 as sole therapy for myocardial ischemia. Circulation 98: 2800-2804
-
(1998)
Circulation
, vol.98
, pp. 2800-2804
-
-
Losordo, D.W.1
-
25
-
-
0032698604
-
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease
-
Symes JF et al. (1999) Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease. Ann Thorac Surg 68: 830-836
-
(1999)
Ann. Thorac. Surg.
, vol.68
, pp. 830-836
-
-
Symes, J.F.1
-
26
-
-
0034730094
-
165 gene transfer for therapeutic angiogenesis in chronic myocardial ischemia
-
165 gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 102: 965-974
-
(2000)
Circulation
, vol.102
, pp. 965-974
-
-
Vale, P.R.1
-
27
-
-
0034767908
-
165 as sole therapy in patients with refractory coronary artery disease - 12-month follow-up: Angiogenic gene therapy
-
165 as sole therapy in patients with refractory coronary artery disease - 12-month follow-up: angiogenic gene therapy. J Intern Med 250: 373-381
-
(2001)
J. Intern. Med.
, vol.250
, pp. 373-381
-
-
Sarkar, N.1
-
28
-
-
0345275979
-
Gene therapy of coronary artery disease with phvegf165 - Early outcome
-
Kolsut P et al. (2003) Gene therapy of coronary artery disease with phvegf165 - early outcome. Kardiol Pol 59: 373-384
-
(2003)
Kardiol. Pol.
, vol.59
, pp. 373-384
-
-
Kolsut, P.1
-
29
-
-
0035162160
-
Simultaneous surgical revascularization and angiogenic gene therapy in diffuse coronary artery disease
-
Huwer H et al. (2001) Simultaneous surgical revascularization and angiogenic gene therapy in diffuse coronary artery disease. Eur J Cardiothorac Surg 20: 1128-134
-
(2001)
Eur. J. Cardiothorac. Surg.
, vol.20
, pp. 1128-1134
-
-
Huwer, H.1
-
30
-
-
0035164701
-
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease: Anesthetic management and results
-
Lathi KG et al. (2001) Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease: anesthetic management and results. Anesth Analg 92: 19-25
-
(2001)
Anesth. Analg.
, vol.92
, pp. 19-25
-
-
Lathi, K.G.1
-
31
-
-
0033165684
-
Catheter-based myocardial gene transfer utilizing nonfluoroscopic electromechanical left ventricular mapping
-
Vale PR et al. (1999) Catheter-based myocardial gene transfer utilizing nonfluoroscopic electromechanical left ventricular mapping. J Am Coll Cardiol 34: 246-254
-
(1999)
J. Am. Coll. Cardiol.
, vol.34
, pp. 246-254
-
-
Vale, P.R.1
-
32
-
-
6644223710
-
Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia
-
Vale PR et al. (2001) Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia. Circulation 103: 2138-2143
-
(2001)
Circulation
, vol.103
, pp. 2138-2143
-
-
Vale, P.R.1
-
33
-
-
0037197740
-
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia
-
Losordo DW et al. (2002) Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation 105: 2012-2018
-
(2002)
Circulation
, vol.105
, pp. 2012-2018
-
-
Losordo, D.W.1
-
34
-
-
2642565248
-
Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: Angiogenic cytokines
-
Losordo DW and Dimmeler S (2004) Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines. Circulation 109: 2487-2491
-
(2004)
Circulation
, vol.109
, pp. 2487-2491
-
-
Losordo, D.W.1
Dimmeler, S.2
-
35
-
-
0033520056
-
Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease
-
Rosengart TK et al. (1999) Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation 100: 468-474
-
(1999)
Circulation
, vol.100
, pp. 468-474
-
-
Rosengart, T.K.1
-
36
-
-
0029877965
-
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
-
Giordano FJ et al. (1996) Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart. Nat Med 2: 534-539
-
(1996)
Nat. Med.
, vol.2
, pp. 534-539
-
-
Giordano, F.J.1
-
37
-
-
0037133624
-
Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris
-
Grines C et al. (2002) Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris. Circulation 105: 1291-1297
-
(2002)
Circulation
, vol.105
, pp. 1291-1297
-
-
Grines, C.1
-
38
-
-
0142107372
-
A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina
-
for the Angiogenic GENe Therapy (AGENT-2) Study Group
-
Grines CL et al. for the Angiogenic GENe Therapy (AGENT-2) Study Group (2003) A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina. J Am Coll Cardiol 42: 1339-1347
-
(2003)
J. Am. Coll. Cardiol.
, vol.42
, pp. 1339-1347
-
-
Grines, C.L.1
-
39
-
-
0033039832
-
Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart
-
Ueda H et al. (1999) Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart. Ann Thorac Surg 67: 1726-1731
-
(1999)
Ann. Thorac. Surg.
, vol.67
, pp. 1726-1731
-
-
Ueda, H.1
-
40
-
-
85047694396
-
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1
-
Zhong J et al. (2003) Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. J Clin Invest 112: 30-41
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 30-41
-
-
Zhong, J.1
-
41
-
-
0036275028
-
Intramyocardial injection of naked DNA encoding HIF-1α/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat
-
Shyu KG et al. (2002) Intramyocardial injection of naked DNA encoding HIF-1α/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc Res 54: 576-583
-
(2002)
Cardiovasc. Res.
, vol.54
, pp. 576-583
-
-
Shyu, K.G.1
-
42
-
-
0036211595
-
Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice
-
Green LA et al. (2002) Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice. Mol Imaging Biol 4: 71-81
-
(2002)
Mol. Imaging Biol.
, vol.4
, pp. 71-81
-
-
Green, L.A.1
-
43
-
-
0037046190
-
Optical imaging of cardiac reporter gene expression in living rats
-
Wu JC et al. (2002) Optical imaging of cardiac reporter gene expression in living rats. Circulation 105: 1631-1634
-
(2002)
Circulation
, vol.105
, pp. 1631-1634
-
-
Wu, J.C.1
-
44
-
-
4043081927
-
Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium
-
Wu JC et al. (2004) Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. Circulation 110: 685-691
-
(2004)
Circulation
, vol.110
, pp. 685-691
-
-
Wu, J.C.1
-
45
-
-
0036100536
-
Non-invasive in vivo monitoring of trackable viruses expressing soluble marker peptides
-
Peng KW et al. (2002) Non-invasive in vivo monitoring of trackable viruses expressing soluble marker peptides. Nat Med 8: 527-531
-
(2002)
Nat. Med.
, vol.8
, pp. 527-531
-
-
Peng, K.W.1
-
46
-
-
1242276573
-
Designing gene delivery vectors for cardiovascular gene therapy
-
Baker AH (2004) Designing gene delivery vectors for cardiovascular gene therapy. Prog Biophys Mol Biol 84: 279-299
-
(2004)
Prog. Biophys. Mol. Biol.
, vol.84
, pp. 279-299
-
-
Baker, A.H.1
-
47
-
-
2942572769
-
Therapeutic angiogenesis and vasculogenesis for ischemic disease: Part II: Cell-based therapies
-
Losordo DW and Dimmeler S (2004) Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. Circulation 109: 2692-2697
-
(2004)
Circulation
, vol.109
, pp. 2692-2697
-
-
Losordo, D.W.1
Dimmeler, S.2
-
48
-
-
12144288784
-
Development of angiogenic cell and gene therapy by transplantation of umbilical cord blood with vascular endothelial growth factor gene
-
Ikeda Y et al. (2004) Development of angiogenic cell and gene therapy by transplantation of umbilical cord blood with vascular endothelial growth factor gene. Hypertens Res 27: 119-128
-
(2004)
Hypertens. Res.
, vol.27
, pp. 119-128
-
-
Ikeda, Y.1
-
49
-
-
2442554080
-
Cellular, but not direct, adenoviral delivery of vascular endothelial growth factor results in improved left ventricular function and neovascularization in dilated ischemic cardiomyopathy
-
Askari A et al. (2004) Cellular, but not direct, adenoviral delivery of vascular endothelial growth factor results in improved left ventricular function and neovascularization in dilated ischemic cardiomyopathy. J Am Coll Cardiol 43: 1908-1914
-
(2004)
J. Am. Coll. Cardiol.
, vol.43
, pp. 1908-1914
-
-
Askari, A.1
-
50
-
-
0037065852
-
Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration
-
Iwaguro H et al. (2002) Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation 105: 732-738
-
(2002)
Circulation
, vol.105
, pp. 732-738
-
-
Iwaguro, H.1
|