AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hindlimb ischemia model

Cardiovascular Research

Volumn 53, Issue 4, 2002, Pages 993-1001

  Shimpo, Masahisa ^a   Ikeda, Uichi ^a   Maeda, Yoshikazu ^a   Takahashi, Masafumi ^a   Miyashita, Hiroshi ^a   Mizukami, Hiroaki ^a   Urabe, Masashi ^a   Kume, Akihiro ^a   Takizawa, Toshihiro ^a   Shibuya, Masabumi ^b   Ozawa, Keiya ^a   Shimada, Kazuyuki ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Angiogenesis; Atherosclerosis; Cytokines; Gene therapy; Growth factors; Ischemia

Indexed keywords

DRUG VEHICLE; RECOMBINANT DNA; VASCULOTROPIN;

ADENO ASSOCIATED VIRUS; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CELL LINE; CONTROLLED STUDY; DRUG STABILITY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; LIMB BLOOD FLOW; LIMB ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REPORTER GENE; SKELETAL MUSCLE; SKIN TEMPERATURE;

ADENOVIRIDAE; ANIMALS; CELLS, CULTURED; COLLATERAL CIRCULATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL GROWTH FACTORS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMODYNAMIC PROCESSES; HINDLIMB; ISCHEMIA; LYMPHOKINES; MALE; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036196808     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00546-6     Document Type: Article

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