-
1
-
-
0022930702
-
Inducibility of kappa immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
-
Sen R., and Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell 47 (1986) 921-928
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
2
-
-
0036234459
-
Missing pieces in the NF-kappaB puzzle
-
Ghosh S., and Karin M. Missing pieces in the NF-kappaB puzzle. Cell 109 Suppl (2002) S81-S96
-
(2002)
Cell
, vol.109
, Issue.SUPPL
-
-
Ghosh, S.1
Karin, M.2
-
3
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M., and Lin A. NF-kappaB at the crossroads of life and death. Nat Immunol 3 (2002) 221-227
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
4
-
-
0033996762
-
The I kappaB kinase (IKK) and NF-kappaB: key elements of proinflammatory signalling
-
Karin M., and Delhase M. The I kappaB kinase (IKK) and NF-kappaB: key elements of proinflammatory signalling. Semin Immunol 12 (2000) 85-98
-
(2000)
Semin Immunol
, vol.12
, pp. 85-98
-
-
Karin, M.1
Delhase, M.2
-
5
-
-
0031897632
-
NF-κB and Rel proteins: evolutionarily conserved mediators of the immune response
-
Ghosh S., May M., and Kopp E. NF-κB and Rel proteins: evolutionarily conserved mediators of the immune response. Annu Rev Immunol 16 (1998) 225-260
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.2
Kopp, E.3
-
6
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
-
Beg A., Sha W., Bronson R., Ghosh S., and Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature 376 (1995) 167-170
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.1
Sha, W.2
Bronson, R.3
Ghosh, S.4
Baltimore, D.5
-
7
-
-
33746228120
-
CK2 and PML: regulating the regulator
-
Lallemand-Breitenbach V., and de The H. CK2 and PML: regulating the regulator. Cell 126 (2006) 244-245
-
(2006)
Cell
, vol.126
, pp. 244-245
-
-
Lallemand-Breitenbach, V.1
de The, H.2
-
8
-
-
0033532386
-
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
-
Li Z.W., Chu W., Hu Y., et al. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med 189 (1999) 1839-1845
-
(1999)
J Exp Med
, vol.189
, pp. 1839-1845
-
-
Li, Z.W.1
Chu, W.2
Hu, Y.3
-
9
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben U., Cao Y., Xiao G., et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 293 (2001) 1495-1499
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
-
10
-
-
0031596140
-
Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts
-
Vincenti M.P., Coon C.I., and Brinckerhoff C.E. Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts. Arthritis Rheum 41 (1998) 1987-1994
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1987-1994
-
-
Vincenti, M.P.1
Coon, C.I.2
Brinckerhoff, C.E.3
-
11
-
-
0031886794
-
Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappa B and CBF-1
-
Miyazawa K., Mori A., Yamamoto K., and Okudaira H. Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappa B and CBF-1. Am J Pathol 152 (1998) 793-803
-
(1998)
Am J Pathol
, vol.152
, pp. 793-803
-
-
Miyazawa, K.1
Mori, A.2
Yamamoto, K.3
Okudaira, H.4
-
12
-
-
0033136318
-
Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion
-
Rahman A., Anwar K.N., True A.L., and Malik A.B. Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion. J Immunol 162 (1999) 5466-5476
-
(1999)
J Immunol
, vol.162
, pp. 5466-5476
-
-
Rahman, A.1
Anwar, K.N.2
True, A.L.3
Malik, A.B.4
-
13
-
-
0034746919
-
NF-κB: a key role in inflammatory diseases
-
Tak P.P., and Firestein G.S. NF-κB: a key role in inflammatory diseases. J Clin Invest 107 (2001) 7-11
-
(2001)
J Clin Invest
, vol.107
, pp. 7-11
-
-
Tak, P.P.1
Firestein, G.S.2
-
14
-
-
0032428729
-
AP-1 and NF-kappa B regulation in rheumatoid arthritis and murine collagen-induced arthritis
-
Han Z.N., Boyle D.L., Manning A.M., and Firestein G.S. AP-1 and NF-kappa B regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 28 (1998) 197-208
-
(1998)
Autoimmunity
, vol.28
, pp. 197-208
-
-
Han, Z.N.1
Boyle, D.L.2
Manning, A.M.3
Firestein, G.S.4
-
15
-
-
0031731150
-
Activation and localization of transcription factor, nuclear factor-kappaB in asthma
-
Hart L.A., Krishnan V.L., Adcock I.M., Barnes P.J., and Chung K.F. Activation and localization of transcription factor, nuclear factor-kappaB in asthma. Am J Respir Crit Care Med 158 (1998) 1585-1592
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1585-1592
-
-
Hart, L.A.1
Krishnan, V.L.2
Adcock, I.M.3
Barnes, P.J.4
Chung, K.F.5
-
16
-
-
0034653834
-
Expression and activation of NF-kappa B in the antrum of the human stomach
-
Van Den Brink G.R., Ten Kate F.J., Ponsioen C.Y., et al. Expression and activation of NF-kappa B in the antrum of the human stomach. J Immunol 164 (2000) 3353-3359
-
(2000)
J Immunol
, vol.164
, pp. 3353-3359
-
-
Van Den Brink, G.R.1
Ten Kate, F.J.2
Ponsioen, C.Y.3
-
17
-
-
0035164415
-
Toll-like receptor-mediated NF-κB activation: a phylogenetically conserved paradigm in innate immunity
-
Zhang G., and Ghosh S. Toll-like receptor-mediated NF-κB activation: a phylogenetically conserved paradigm in innate immunity. J Clin Invest 107 (2001) 13-19
-
(2001)
J Clin Invest
, vol.107
, pp. 13-19
-
-
Zhang, G.1
Ghosh, S.2
-
18
-
-
0033966411
-
Toll signaling pathways in the innate immune response
-
Anderson K.V. Toll signaling pathways in the innate immune response. Curr Opin Immunol 12 (2000) 13-19
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 13-19
-
-
Anderson, K.V.1
-
19
-
-
0033844166
-
Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes
-
Muzio M., Polentarutti N., Bosisio D., Prahladan M.K., and Mantovani A. Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes. J Leukoc Biol 67 (2000) 450-456
-
(2000)
J Leukoc Biol
, vol.67
, pp. 450-456
-
-
Muzio, M.1
Polentarutti, N.2
Bosisio, D.3
Prahladan, M.K.4
Mantovani, A.5
-
20
-
-
0034746288
-
NF-κB in neuronal plasticity and neurodegenerative disorders
-
Mattson M.P., and Camandola S. NF-κB in neuronal plasticity and neurodegenerative disorders. J Clin Invest 107 (2001) 247-254
-
(2001)
J Clin Invest
, vol.107
, pp. 247-254
-
-
Mattson, M.P.1
Camandola, S.2
-
21
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F., Wyllie A.H., and Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26 (1972) 239-257
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
22
-
-
0019225636
-
Cell death: the significance of apoptosis
-
Wyllie A.H., Kerr J.F., and Currie A.R. Cell death: the significance of apoptosis. Int Rev Cytol 68 (1980) 251-306
-
(1980)
Int Rev Cytol
, vol.68
, pp. 251-306
-
-
Wyllie, A.H.1
Kerr, J.F.2
Currie, A.R.3
-
23
-
-
0842281645
-
Cell death: critical control points
-
Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 (2004) 205-219
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
24
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature 407 (2000) 770-776
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
25
-
-
26444605834
-
IKK/NF-κB signaling: balancing life and death - a new approach to cancer therapy
-
Luo J.-L., Kamata H., and Karin M. IKK/NF-κB signaling: balancing life and death - a new approach to cancer therapy. J Clin Invest 115 (2005) 2625-2632
-
(2005)
J Clin Invest
, vol.115
, pp. 2625-2632
-
-
Luo, J.-L.1
Kamata, H.2
Karin, M.3
-
26
-
-
1642553460
-
To be or not to be: NF-kappa B is the answer. Role of Rel/NF-kappa B in the regulation of apoptosis
-
Kucharczak J., Simmons M.J., Fan Y., and Gelinas C. To be or not to be: NF-kappa B is the answer. Role of Rel/NF-kappa B in the regulation of apoptosis. Oncogene 22 (2003) 8961-8982
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.3
Gelinas, C.4
-
27
-
-
0344496062
-
IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha
-
Maeda S., Chang L., Li Z.W., Luo J.L., Leffert H., and Karin M. IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha. Immunity 19 (2003) 725-737
-
(2003)
Immunity
, vol.19
, pp. 725-737
-
-
Maeda, S.1
Chang, L.2
Li, Z.W.3
Luo, J.L.4
Leffert, H.5
Karin, M.6
-
28
-
-
9444245015
-
Linking JNK signaling to NF-kappaB: a key to survival
-
Papa S., Zazzeroni F., Pham C.G., Bubici C., and Franzoso G. Linking JNK signaling to NF-kappaB: a key to survival. J Cell Sci 117 (2004) 5197-5208
-
(2004)
J Cell Sci
, vol.117
, pp. 5197-5208
-
-
Papa, S.1
Zazzeroni, F.2
Pham, C.G.3
Bubici, C.4
Franzoso, G.5
-
29
-
-
0042525938
-
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
Sakon S., Xue X., Takekawa M., et al. NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J 22 (2003) 3898-3909
-
(2003)
EMBO J
, vol.22
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
-
30
-
-
0033576675
-
More than one way to die: apoptosis, necrosis and reactive oxygen damage
-
Fiers W., Beyaert R., Declercq W., and Vandenabeele P. More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 18 (1999) 7719-7730
-
(1999)
Oncogene
, vol.18
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
31
-
-
2942593988
-
Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS
-
Sasazuki T., Okazaki T., Tada K., et al. Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS. Mol Immunol 41 (2004) 547-551
-
(2004)
Mol Immunol
, vol.41
, pp. 547-551
-
-
Sasazuki, T.1
Okazaki, T.2
Tada, K.3
-
32
-
-
10044265209
-
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
-
Ventura J.J., Cogswell P., Flavell R.A., Baldwin Jr. A.S., and Davis R.J. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev 18 (2004) 2905-2915
-
(2004)
Genes Dev
, vol.18
, pp. 2905-2915
-
-
Ventura, J.J.1
Cogswell, P.2
Flavell, R.A.3
Baldwin Jr., A.S.4
Davis, R.J.5
-
33
-
-
0032588186
-
NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1
-
Guttridge D.C., Albanese C., Reuther J.Y., Pestell R.G., and Baldwin Jr. A.S. NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 19 (1999) 5785-5799
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5785-5799
-
-
Guttridge, D.C.1
Albanese, C.2
Reuther, J.Y.3
Pestell, R.G.4
Baldwin Jr., A.S.5
-
34
-
-
0035139792
-
Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
-
Yamamoto Y., and Gaynor R.B. Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer. J Clin Invest 107 (2001) 135-142
-
(2001)
J Clin Invest
, vol.107
, pp. 135-142
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
35
-
-
0032588317
-
NF-κB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
-
Wang C.Y., Guttridge D.C., Mayo M.W., and Baldwin Jr. A.S. NF-κB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol Cell Biol 19 (1999) 5923-5929
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5923-5929
-
-
Wang, C.Y.1
Guttridge, D.C.2
Mayo, M.W.3
Baldwin Jr., A.S.4
-
36
-
-
0035966071
-
NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells
-
Bian X., McAllister-Lucas L.M., Shao F., et al. NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells. J Biol Chem 276 (2001) 48921-48929
-
(2001)
J Biol Chem
, vol.276
, pp. 48921-48929
-
-
Bian, X.1
McAllister-Lucas, L.M.2
Shao, F.3
-
37
-
-
0037421484
-
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
-
Dajee M., Lazarov M., Zhang J.Y., et al. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 421 (2003) 639-643
-
(2003)
Nature
, vol.421
, pp. 639-643
-
-
Dajee, M.1
Lazarov, M.2
Zhang, J.Y.3
-
38
-
-
0032954928
-
Transcriptional cross talk between NF-kappa B and p53
-
Webster G.A., and Perkins N.D. Transcriptional cross talk between NF-kappa B and p53. Mol Cell Biol 19 (1999) 3485-3495
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
39
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan K.M., Enrst M.K., Rice N.R., and Vousden K.H. Role of NF-kappaB in p53-mediated programmed cell death. Nature 404 (2000) 892-897
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Enrst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
40
-
-
0035139943
-
Hostile takeovers: viral appropriation of the NF-κB pathway
-
Hiscott J., Kwon H., and Génin P. Hostile takeovers: viral appropriation of the NF-κB pathway. J Clin Invest 107 (2001) 143-151
-
(2001)
J Clin Invest
, vol.107
, pp. 143-151
-
-
Hiscott, J.1
Kwon, H.2
Génin, P.3
-
41
-
-
0032568816
-
The Tax oncoprotein of HTLV-I associates with and persistently activates IκB kinases containing IKKα and IKKβ
-
Chu Z., DiDonato J., Hawiger J., and Ballard D. The Tax oncoprotein of HTLV-I associates with and persistently activates IκB kinases containing IKKα and IKKβ. J Biol Chem 273 (1998) 15891-15894
-
(1998)
J Biol Chem
, vol.273
, pp. 15891-15894
-
-
Chu, Z.1
DiDonato, J.2
Hawiger, J.3
Ballard, D.4
-
42
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin A.S. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 107 (2001) 241-246
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
43
-
-
0030882666
-
Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity which is required for cellular transformation
-
Finco T.S., Westwick J.K., Norris J.L., Beg A.A., Der C.J., and Baldwin Jr. A.S. Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity which is required for cellular transformation. J Biol Chem 272 (1997) 24113-24116
-
(1997)
J Biol Chem
, vol.272
, pp. 24113-24116
-
-
Finco, T.S.1
Westwick, J.K.2
Norris, J.L.3
Beg, A.A.4
Der, C.J.5
Baldwin Jr., A.S.6
-
44
-
-
0032034216
-
A requirement for NF-κB activation in Bcr-Abl-mediated transformation
-
Reuther J., Reuther G., Cortez D., Pendergast A.M., and Baldwin A. A requirement for NF-κB activation in Bcr-Abl-mediated transformation. Genes Dev 12 (1998) 968-981
-
(1998)
Genes Dev
, vol.12
, pp. 968-981
-
-
Reuther, J.1
Reuther, G.2
Cortez, D.3
Pendergast, A.M.4
Baldwin, A.5
-
45
-
-
4644324186
-
NF-κB functions as a tumor promoter in inflammation-associated cancer
-
Pikarsky E., Porat R.M., Stein I., et al. NF-κB functions as a tumor promoter in inflammation-associated cancer. Nature 431 (2004) 461-466
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
46
-
-
0034544619
-
Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma
-
Tai D.I., Tsai S.L., Chang Y.H., et al. Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer 89 (2000) 2274-2281
-
(2000)
Cancer
, vol.89
, pp. 2274-2281
-
-
Tai, D.I.1
Tsai, S.L.2
Chang, Y.H.3
-
47
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling
-
Van Hogerlinden M., Rozell B.L., Ährlund-Richter L., and Toftgard R. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling. Cancer Res 59 (1999) 3299-3303
-
(1999)
Cancer Res
, vol.59
, pp. 3299-3303
-
-
Van Hogerlinden, M.1
Rozell, B.L.2
Ährlund-Richter, L.3
Toftgard, R.4
-
48
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated colon cancer
-
Greten F.R., Eckmann L., Greten T.F., et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated colon cancer. Cell 118 (2004) 285-296
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
49
-
-
21244472975
-
IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
Maeda S., Kamata H., Luo J.-L., Leffert H., and Karin M. IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121 (2005) 977-990
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.-L.3
Leffert, H.4
Karin, M.5
-
50
-
-
26444584958
-
Nuclear factor-kappaB and liver carcinogenesis
-
Arsura M., and Cavin L.G. Nuclear factor-kappaB and liver carcinogenesis. Cancer Lett 229 (2005) 157-169
-
(2005)
Cancer Lett
, vol.229
, pp. 157-169
-
-
Arsura, M.1
Cavin, L.G.2
-
51
-
-
21544441173
-
NF-κB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein
-
Brandt S., Kwok T., Hartig R., König W., and Backert S. NF-κB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc Natl Acad Sci USA 102 (2005) 9300-9305
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9300-9305
-
-
Brandt, S.1
Kwok, T.2
Hartig, R.3
König, W.4
Backert, S.5
-
52
-
-
1642334954
-
NF-κB activation in esophageal adenocarcinoma. Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy
-
Abdel-Latif M.M.M., O'Riordan J., Windle H.J., et al. NF-κB activation in esophageal adenocarcinoma. Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Ann Surg 239 (2004) 491-500
-
(2004)
Ann Surg
, vol.239
, pp. 491-500
-
-
Abdel-Latif, M.M.M.1
O'Riordan, J.2
Windle, H.J.3
-
54
-
-
0034306969
-
Blockade of nuclear factor-κB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8
-
Huang S., Robinson J.B., DeGuzman A., Bucana C.D., and Filder I.J. Blockade of nuclear factor-κB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res 60 (2000) 5334-5339
-
(2000)
Cancer Res
, vol.60
, pp. 5334-5339
-
-
Huang, S.1
Robinson, J.B.2
DeGuzman, A.3
Bucana, C.D.4
Filder, I.J.5
-
55
-
-
0344270811
-
Cervical cancer: etiology, pathogenesis, treatment and future vaccines
-
Ghim S.J., Basu P.S., and Jenson A. Cervical cancer: etiology, pathogenesis, treatment and future vaccines. Asian Pac J Cancer Prev 3 (2002) 207-214
-
(2002)
Asian Pac J Cancer Prev
, vol.3
, pp. 207-214
-
-
Ghim, S.J.1
Basu, P.S.2
Jenson, A.3
-
56
-
-
0036704791
-
Human papilloma virus (HPV) and cervical cancer
-
Furomoto H.I.M., and Irahara. Human papilloma virus (HPV) and cervical cancer. J Med Invest 49 (2002) 124-133
-
(2002)
J Med Invest
, vol.49
, pp. 124-133
-
-
Furomoto, H.I.M.1
Irahara2
-
57
-
-
9644266549
-
Dual apoptotic effect of Xrel c-Rel/NF-kappaB homolog in human cervical cancer cells
-
Shehata M., Shehata M., Shehata F., and Pater A. Dual apoptotic effect of Xrel c-Rel/NF-kappaB homolog in human cervical cancer cells. Cell Biol Int 28 (2004) 895-904
-
(2004)
Cell Biol Int
, vol.28
, pp. 895-904
-
-
Shehata, M.1
Shehata, M.2
Shehata, F.3
Pater, A.4
-
58
-
-
26844532114
-
Rel/nuclear factor-kappa B apoptosis pathways in human cervical cancer cells
-
Shehata M.F. Rel/nuclear factor-kappa B apoptosis pathways in human cervical cancer cells. Cancer Cell Int 5 (2005) 10
-
(2005)
Cancer Cell Int
, vol.5
, pp. 10
-
-
Shehata, M.F.1
-
59
-
-
0033602024
-
Overexpression of anti-apoptotic gene BAG-I in human cervical cancer
-
Yang X., Hao Y., Ferenczy A., Tang S.C., and Pater A. Overexpression of anti-apoptotic gene BAG-I in human cervical cancer. Exp Cell Res 247 (1999) 200-207
-
(1999)
Exp Cell Res
, vol.247
, pp. 200-207
-
-
Yang, X.1
Hao, Y.2
Ferenczy, A.3
Tang, S.C.4
Pater, A.5
-
60
-
-
0035862151
-
Nuclear factor-κB-dependent expression of metastases suppressor KA11/CD82 gene in lung cancer cell lines expressing mutant p53
-
Shinohara T., Miki T., Nishimura N., et al. Nuclear factor-κB-dependent expression of metastases suppressor KA11/CD82 gene in lung cancer cell lines expressing mutant p53. Cancer Res 61 (2001) 673-678
-
(2001)
Cancer Res
, vol.61
, pp. 673-678
-
-
Shinohara, T.1
Miki, T.2
Nishimura, N.3
-
61
-
-
0029740215
-
Down regulation of KA11 metastases suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss
-
Dong J.-T., Suzuki H., Pin S.S., et al. Down regulation of KA11 metastases suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss. Cancer Res 56 (1996) 4387-4390
-
(1996)
Cancer Res
, vol.56
, pp. 4387-4390
-
-
Dong, J.-T.1
Suzuki, H.2
Pin, S.S.3
-
62
-
-
0029854919
-
KA11 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases
-
Guo X., Friess H., Graber H.U., et al. KA11 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases. Cancer Res 56 (1996) 4876-4880
-
(1996)
Cancer Res
, vol.56
, pp. 4876-4880
-
-
Guo, X.1
Friess, H.2
Graber, H.U.3
-
63
-
-
0029932247
-
Correlation of KA11/CD82 gene expression with good prognosis in patients with non-small cell lung cancer
-
Adachi M., Taki T., Ikei Y., Huang C.-L., Higashiyama M., and Miyake M. Correlation of KA11/CD82 gene expression with good prognosis in patients with non-small cell lung cancer. Cancer Res 56 (1996) 1751-1755
-
(1996)
Cancer Res
, vol.56
, pp. 1751-1755
-
-
Adachi, M.1
Taki, T.2
Ikei, Y.3
Huang, C.-L.4
Higashiyama, M.5
Miyake, M.6
-
64
-
-
1842413105
-
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The non-Hodgkin's lymphoma classification project
-
A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The non-Hodgkin's lymphoma classification project. Blood 89 (1997) 3909-3918
-
(1997)
Blood
, vol.89
, pp. 3909-3918
-
-
-
66
-
-
0034873899
-
Diffuse large cell lymphoma
-
Coiffier B. Diffuse large cell lymphoma. Curr Opin Oncol 13 (2001) 325-334
-
(2001)
Curr Opin Oncol
, vol.13
, pp. 325-334
-
-
Coiffier, B.1
-
67
-
-
0037142053
-
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B cell lymphoma
-
Rosenwald A., Wright G., Chan W.C., et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B cell lymphoma. N Engl J Med 346 (2002) 1937-1947
-
(2002)
N Engl J Med
, vol.346
, pp. 1937-1947
-
-
Rosenwald, A.1
Wright, G.2
Chan, W.C.3
-
68
-
-
18244409933
-
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
-
Shipp M.A., Ross K.N., Tamayo P., et al. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med 8 (2002) 68-74
-
(2002)
Nat Med
, vol.8
, pp. 68-74
-
-
Shipp, M.A.1
Ross, K.N.2
Tamayo, P.3
-
69
-
-
0027972513
-
Mutations of the RET proto-oncogene in Hirschsprung's disease
-
Edery P., Lyonnet S., Mulligan L.M., et al. Mutations of the RET proto-oncogene in Hirschsprung's disease. Nature 367 (1994) 378-380
-
(1994)
Nature
, vol.367
, pp. 378-380
-
-
Edery, P.1
Lyonnet, S.2
Mulligan, L.M.3
-
70
-
-
0028174024
-
Mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
-
Hofstra R.M., Landsvater R.M., Ceccherini I., et al. Mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 367 (1994) 375-376
-
(1994)
Nature
, vol.367
, pp. 375-376
-
-
Hofstra, R.M.1
Landsvater, R.M.2
Ceccherini, I.3
-
71
-
-
0028838086
-
Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations
-
Asai N., Iwashita T., Matsuyama M., and Takahashi M. Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations. Mol Cell Biol 15 (1995) 1613-1619
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1613-1619
-
-
Asai, N.1
Iwashita, T.2
Matsuyama, M.3
Takahashi, M.4
-
72
-
-
0028914683
-
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B
-
Santoro M., Carlomagno F., Romano A., et al. Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science 267 (1995) 381-383
-
(1995)
Science
, vol.267
, pp. 381-383
-
-
Santoro, M.1
Carlomagno, F.2
Romano, A.3
-
73
-
-
0035354187
-
Nuclear factor-κB is constitutively active in C-cell carcinoma and required for RET-induced transformation
-
Ludwing L., Kessler H., Wagner M., et al. Nuclear factor-κB is constitutively active in C-cell carcinoma and required for RET-induced transformation. Cancer Res 61 (2001) 4526-4535
-
(2001)
Cancer Res
, vol.61
, pp. 4526-4535
-
-
Ludwing, L.1
Kessler, H.2
Wagner, M.3
-
74
-
-
0035253381
-
The von Hippel-Lindau tumor suppressor protein
-
Ivan M., and Kaelin W.G. The von Hippel-Lindau tumor suppressor protein. Curr Opin Gen Dev 11 (2001) 27-34
-
(2001)
Curr Opin Gen Dev
, vol.11
, pp. 27-34
-
-
Ivan, M.1
Kaelin, W.G.2
-
75
-
-
0242694963
-
The von Hippel-Lindau tumor suppressor protein synthesizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by supressing the nuclear factor-κB-dependent antiapoptotic pathway
-
Qi H., and Ohh M. The von Hippel-Lindau tumor suppressor protein synthesizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by supressing the nuclear factor-κB-dependent antiapoptotic pathway. Cancer Res 63 (2003) 7076-7080
-
(2003)
Cancer Res
, vol.63
, pp. 7076-7080
-
-
Qi, H.1
Ohh, M.2
-
76
-
-
1842788118
-
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition
-
Lind M.H., Rozell B., Wallin R.P.A., et al. Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition. Proc Natl Acad Sci USA 101 (2004) 4972-4977
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4972-4977
-
-
Lind, M.H.1
Rozell, B.2
Wallin, R.P.A.3
-
77
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB
-
Wang C.Y., Mayo M.W., and Baldwin A.S.J. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274 (1996) 784-787
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin, A.S.J.3
-
78
-
-
0029992609
-
Suppression of TNF-induced apoptosis by NF-κB
-
Van Antwerp D.J., Martin S.J., Kafri T., Green D.R., and Verma I.M. Suppression of TNF-induced apoptosis by NF-κB. Science 274 (1996) 787-789
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
79
-
-
16644395843
-
Blocking anti-apoptosis as a strategy for cancer chemotherapy. NF-κB as a target
-
Monks N.R., Biswas D.K., and Pardee A.B. Blocking anti-apoptosis as a strategy for cancer chemotherapy. NF-κB as a target. J Cell Biochem 92 (2004) 646-650
-
(2004)
J Cell Biochem
, vol.92
, pp. 646-650
-
-
Monks, N.R.1
Biswas, D.K.2
Pardee, A.B.3
-
80
-
-
19944427042
-
Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
-
Frelin C., Imbert V., Griessinger E., et al. Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells. Blood 105 (2005) 804-811
-
(2005)
Blood
, vol.105
, pp. 804-811
-
-
Frelin, C.1
Imbert, V.2
Griessinger, E.3
-
81
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
Huang P., Feng L., Oldham E.A., Deating M.J., and Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 407 (2000) 390-395
-
(2000)
Nature
, vol.407
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Deating, M.J.4
Plunkett, W.5
-
82
-
-
0346505340
-
The IKK NF-κB system: a treasure trove for drug development
-
Karin M., Yamamoto Y., and Wang Q.M. The IKK NF-κB system: a treasure trove for drug development. Nat Rev Drug Discov 3 (2004) 17-26
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
83
-
-
0036020941
-
NF-κB as a therapeutic target in cancer
-
Orlowski R.Z., and Baldwin Jr. A.S. NF-κB as a therapeutic target in cancer. Trends Mol Med 8 (2002) 385-389
-
(2002)
Trends Mol Med
, vol.8
, pp. 385-389
-
-
Orlowski, R.Z.1
Baldwin Jr., A.S.2
-
84
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
-
Yin M.-J., Yamamoto Y., and Gaynor R.B. The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β. Nature 396 (1998) 77-80
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.-J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
85
-
-
0032032469
-
Sulfasalazine: a potent and specific inhibitor of NF-κB
-
Wahl C., Liptay S., Adler G., and Schmid R.M. Sulfasalazine: a potent and specific inhibitor of NF-κB. J Clin Invest 101 (1997) 1163-1174
-
(1997)
J Clin Invest
, vol.101
, pp. 1163-1174
-
-
Wahl, C.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
86
-
-
0028867899
-
Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis
-
Auphan N., DiDonato J.A., Rosette C., Helmberg A., and Karin M. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270 (1995) 286-290
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
87
-
-
0034636021
-
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
-
De Bosscher K., Berghe V., Vermeulen L., Plaisance S., Boone E., and Haegeman G. Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc Natl Acad Sci USA 97 (2000) 3919-3924
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3919-3924
-
-
De Bosscher, K.1
Berghe, V.2
Vermeulen, L.3
Plaisance, S.4
Boone, E.5
Haegeman, G.6
-
89
-
-
0036023407
-
A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies
-
Aghajanian C., Soignet S., Dizon D., et al. A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin Cancer Res 8 (2002) 2505-2511
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2505-2511
-
-
Aghajanian, C.1
Soignet, S.2
Dizon, D.3
-
90
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson P.G., Barlogie B., Berenson J., et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. New Engl J Med 348 (2003) 2609-2617
-
(2003)
New Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
-
91
-
-
1442306054
-
IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium
-
Egan L.J., Eckmann L., Greten F., et al. IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium. Proc Natl Acad Sci USA 101 (2004) 2452-2457
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2452-2457
-
-
Egan, L.J.1
Eckmann, L.2
Greten, F.3
|