KAI1 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases

Cancer Research

Volumn 56, Issue 21, 1996, Pages 4876-4880

  Guo, Xiaozhong ^a   Friess, Helmut ^a   Graber, Hans U ^a   Kashiwagi, Mikiya ^a   Zimmermann, Arthur ^a   Korc, Murray ^b   Büchler, Markus W ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CANCER SURVIVAL; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; NORTHERN BLOTTING; PANCREAS CANCER; PANCREAS RESECTION; PANCREATICODUODENECTOMY; PRIORITY JOURNAL;

ADULT; AGED; ANTIGENS, CD; BLOTTING, NORTHERN; FEMALE; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; HUMANS; IN SITU HYBRIDIZATION; KANGAI-1 PROTEIN; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER;

EID: 0029854919     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Mark, S. R, Carlos, C., Albert, B S, Ralph, H. H., Luis, D. C, Charles, J. Y., and Scotte, E. K p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdelections. Cancer Res., 54: 3025-3033, 1994.
2. Sidebottom, E., and Clark, S. R. Cell fusion segregates progressive growth from metastasis. Br. J. Cancer, 47: 399-406, 1983.
3. Dong, J. T., Lamb, P. W., Rinker-Schaeffer, C. W., Vukanovic, J., Ichikawa, T., Isaacs, J. T., and Barrett, J. C. KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science (Washington DC), 268: 884-886, 1995.
4. Nelson, N. J. Combining prostate markers may yield useful screening tool. J. Natl. Cancer Inst., 87: 1281-1283, 1995
5. Hermanek, P, and Sobin, L. H. TNM classification of malignant tumor, 4th Ed Union International Contre Cancer Geneva, pp. 71-73. New York: Springer-Verlag, 1992.
6. Muller, C. F., Fatzer, R., Beek, K, Vandevelde, M., and Zurbriggen, A. Studies on canine distemper virus persistence in the control nervous system Acta Neuropathol., 89: 438-455, 1995
7. Cox, K. H., Deleon, D. V., Augerer, L. M., and Augerer, R. C. Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol., 101, 485-502, 1984
8. Korc, M, Chandrasekar, B., Yamanaka, Y., Friess, H., Buchler, M., and Beger, H. G. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increase in levels of epidermal growth factor and transforming growth factor alpha J. Clin Invest., 90: 1353-1360, 1992
9. Friess, H., Yamanaka, Y., Büchler, M. W, Beger, H G., Kobrin, M. S., Baldwin, R L., and Korc, M Enhanced expression of the type II transforming growth factor-beta receptor in human pancreatic cancer cells without alteration of type III receptor expression. Cancer Res, 53: 2704-2707, 1993.
10. Guillem, J. G, Levy, M. F., Hsieh, L L., Johnson, M D., Logerfo, P., Forde, K A., and Weinstein, I. B Increased levels of phorbin, c-myc and ornithine decarboxylase RNAs in human colon cancer. Mol. Carcinog., 3: 68-74, 1990.
11. Graber, H. U., Müller, C. F, Vandevelde, M., and Zurbriggen, A Restricted infection with canine distemper virus leads to down-regulation of myelin gene transcription in cultured oligodendrocytes. Acta Neuropathol, 90: 312-318, 1995.
12. Gress, T M., Muller-Pillasch, F., Lerch, M M., Friess, H., Büchler, M, and Adler, G. Expression and in situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int. J Cancer, 62: 407-413, 1995.
13. Steeg, P. S., Bevilacqua, G., Kopper, L, Thorgeirsson, U P., Talmadge, J. B, Liotta, L. A., and Sobel, M. E Evidence for a novel gene associated with low tumor metastatic potential. J Natl. Cancer Inst., 80: 200-204, 1988.
14. Nakamori, S, Ishikawa, O., Ohigashi, H, Kameyama, M, Furukawa, H., Sasaki, Y., Inaji, H., Higashiyama, M., Imaoka, S., Iwanaga, T., Funai, H, Wada, A., and Kimura, N. Expression of nucleoside diphosphate kinase/nm23 gene product in human pancreatic cancer: an association with lymph node metastasis and tumor invasion. Clin. Exp Metastasis, 11, 151-158, 1993
15. Friess, H., Yamanaka, Y., Büchler, M., Ebert, M., Beger, H. G., Gold, L I., and Korc, M. Enhanced expression of transforming growth factor β isoforms in pancreatic cancer correlates with decreased survival Gastroenterology, 105: 1846-1856, 1993.
16. Barton, C M, Staddon, S L., Hughes, C M, Hall, P A., Sullivan, O. C., Kloppel, G., Theis, B., Russell, R C G., Neoptolemos, J., Williamson, R. C. N., Lane, D. P., and Lemoine, N. R. Abnormal expression of the p53 tumor suppressor gene in pancreatic cancer. Br. J. Cancer, 64: 1076-1082, 1991.
17. Horejsi, V., and Vlcek, C Novel structurally distinct family of leukocyte surface glycoproteins including CD9, CD37, CD53 and CD63. FEBS Lett., 288: 1-4, 1991
18. Miyake, M., Koyama, M., Seno, M., and Ikeyama, S Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility. Exp J. Med., 174: 1347-1354, 1991
19. Hotta, H, Ross, A. H., Huebner, K., Isobe, M., Wendeborn, S, Chao, M. V. Ricciardi, R. P., Tsujimoto, T., Croce, C. M., and Koprowski, H. Molecular cloning and characterization of an antigen associated with early stages of melanoma tumor progression. Cancer Res., 48: 2955-2962, 1988
20. Metzelaar, M. J., Wijngaard, P. L. J., Peters, P. J., Sixma, J. J., Nieuwenhuis, H. K., and Clevers, H. C CD63 antigen J. Biol. Chem., 266: 3239-3245, 1991.
21. Marx, J. New clue to prostate cancer spread Science (Washington DC), 268: 799-800, 1995.