Design and synthesis of compounds that extend yeast replicative lifespan

Aging Cell

Volumn 6, Issue 1, 2007, Pages 35-43

  Yang, Hongying ^a   Baur, Joseph A ^a   Chen, Allen ^a   Miller, Christine ^a   Sinclair, David A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Lifespan; Longevity; Resveratrol; SIRT1; Sirtuins; STACs

Indexed keywords

3,5 DIHYDROXY 4' ACETOXYSTILBENE; 3,5 DIHYDROXY 4' ETHYLSTILBENE; 3,5 DIHYDROXY 4' METHOXYSTILBENE; 3,5 DIHYDROXY 4' METHYLSTILBENE; 3,5 DIHYDROXY 4' THIOMETHYLSTILBENE; BENZENE DERIVATIVE; FISETIN; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER; CELL DIVISION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIABETES MELLITUS; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG HYDROLYSIS; DRUG POTENCY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GENE IDENTIFICATION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION; YEAST CELL;

CELL AGING; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ENZYME ACTIVATION; FLAVONOIDS; HUMANS; MOLECULAR STRUCTURE; SACCHAROMYCES CEREVISIAE; SIRTUINS; STILBENES;

SACCHAROMYCES CEREVISIAE;

EID: 33846449466     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2006.00259.x     Document Type: Article

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