-
1
-
-
0036753953
-
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
-
Avalos J.L., Celic I., Muhammad S., Cosgrove M.S., Boeke J.D., Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Mol. Cell. 10:2002;523-535.
-
(2002)
Mol. Cell
, vol.10
, pp. 523-535
-
-
Avalos, J.L.1
Celic, I.2
Muhammad, S.3
Cosgrove, M.S.4
Boeke, J.D.5
Wolberger, C.6
-
2
-
-
0037023326
-
The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation
-
Bell S.D., Botting C.H., Wardleworth B.N., Jackson S.P., White M.F. The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation. Science. 296:2002;148-151.
-
(2002)
Science
, vol.296
, pp. 148-151
-
-
Bell, S.D.1
Botting, C.H.2
Wardleworth, B.N.3
Jackson, S.P.4
White, M.F.5
-
3
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kunstleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S.et al. Crystallography & NMR system. a new software suite for macromolecular structure determination Acta Crystallogr. D54:1998;905-921.
-
(1998)
Acta Crystallogr.
, vol.D54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
4
-
-
0037072885
-
Structural basis for the NAD-dependent deacetylase mechanism of Sir2
-
Chang J.H., Kim H.C., Hwang K.Y., Lee J.W., Jackson S.P., Bell S.D., Cho Y. Structural basis for the NAD-dependent deacetylase mechanism of Sir2. J. Biol. Chem. 277:2002;34489-34498.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34489-34498
-
-
Chang, J.H.1
Kim, H.C.2
Hwang, K.Y.3
Lee, J.W.4
Jackson, S.P.5
Bell, S.D.6
Cho, Y.7
-
5
-
-
0033539092
-
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
-
Finnin M.S., Donigian J.R., Cohen A., Richon V.M., Rifkind R.A., Marks P.A., Breslow R., Pavletich N.P. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature. 401:1999;188-193.
-
(1999)
Nature
, vol.401
, pp. 188-193
-
-
Finnin, M.S.1
Donigian, J.R.2
Cohen, A.3
Richon, V.M.4
Rifkind, R.A.5
Marks, P.A.6
Breslow, R.7
Pavletich, N.P.8
-
8
-
-
0032750220
-
Diverse and dynamic functions of the Sir silencing complex
-
Guarente L. Diverse and dynamic functions of the Sir silencing complex. Nat. Genet. 23:1999;281-285.
-
(1999)
Nat. Genet.
, vol.23
, pp. 281-285
-
-
Guarente, L.1
-
9
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev. 14:2000;1021-1026.
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
10
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S., Armstrong C.M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 403:2000;795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
11
-
-
0037166269
-
Structural identification of 2′- and 3′-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta-NAD+-dependent histone/protein deacetylases
-
Jackson M.D., Denu J.M. Structural identification of 2′- and 3′-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta-NAD+-dependent histone/protein deacetylases. J. Biol. Chem. 277:2002;18535-18544.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18535-18544
-
-
Jackson, M.D.1
Denu, J.M.2
-
12
-
-
0000356656
-
A graphics model building and refinement system for macromolecules
-
Jones T.A. A graphics model building and refinement system for macromolecules. J. Appl. Crystallogr. 11:1978;268-272.
-
(1978)
J. Appl. Crystallogr.
, vol.11
, pp. 268-272
-
-
Jones, T.A.1
-
13
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
Landry J., Sutton A., Tafrov S.T., Heller R.C., Stebbins J., Pillus L., Sternglanz R. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc. Natl. Acad. Sci. USA. 97:2000;5807-5811.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
Sternglanz, R.7
-
14
-
-
0029591894
-
Silencing and heritable domains of gene expression
-
Loo S., Rine J. Silencing and heritable domains of gene expression. Annu. Rev. Cell Dev. Biol. 11:1995;519-548.
-
(1995)
Annu. Rev. Cell Dev. Biol.
, vol.11
, pp. 519-548
-
-
Loo, S.1
Rine, J.2
-
15
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell. 107:2001;137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
16
-
-
0035662888
-
Structure of histone deacetylases: Insights into substrate recognition and catalysis
-
Marmorstein R. Structure of histone deacetylases. insights into substrate recognition and catalysis Structure. 9:2001;1127-1133.
-
(2001)
Structure
, vol.9
, pp. 1127-1133
-
-
Marmorstein, R.1
-
17
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
Min J., Landry J., Sternglanz R., Xu R.M. Crystal structure of a SIR2 homolog-NAD complex. Cell. 105:2001;269-279.
-
(2001)
Cell
, vol.105
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.M.4
-
18
-
-
84920325457
-
AMoRe: An automated package for molecular replacement
-
Navaza J. AMoRe. an automated package for molecular replacement Acta Crystallogr. A50:1994;157-163.
-
(1994)
Acta Crystallogr.
, vol.A50
, pp. 157-163
-
-
Navaza, J.1
-
20
-
-
0035863153
-
A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
-
Perrod S., Cockell M.M., Laroche T., Renauld H., Ducrest A.L., Bonnard C., Gasser S.M. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J. 20:2001;197-209.
-
(2001)
EMBO J.
, vol.20
, pp. 197-209
-
-
Perrod, S.1
Cockell, M.M.2
Laroche, T.3
Renauld, H.4
Ducrest, A.L.5
Bonnard, C.6
Gasser, S.M.7
-
21
-
-
0033517354
-
Structure of the Tetrahymena GCN5 bound to coenzyme-A and a histone H3 peptide
-
Rojas J.R., Trievel R.C., Zhou J., Mo Y., Li X., Berger S.L., Allis D., Marmorstein R. Structure of the Tetrahymena GCN5 bound to coenzyme-A and a histone H3 peptide. Nature. 401:1999;93-98.
-
(1999)
Nature
, vol.401
, pp. 93-98
-
-
Rojas, J.R.1
Trievel, R.C.2
Zhou, J.3
Mo, Y.4
Li, X.5
Berger, S.L.6
Allis, D.7
Marmorstein, R.8
-
22
-
-
0035951072
-
Chemistry of gene silencing: The mechanism of NAD+-dependent deacetylation reactions
-
Sauve A.A., Celic I., Avalos J., Deng H., Boeke J.D., Schramm V.L. Chemistry of gene silencing. the mechanism of NAD+-dependent deacetylation reactions Biochemistry. 40:2001;15456-15463.
-
(2001)
Biochemistry
, vol.40
, pp. 15456-15463
-
-
Sauve, A.A.1
Celic, I.2
Avalos, J.3
Deng, H.4
Boeke, J.D.5
Schramm, V.L.6
-
24
-
-
12944283150
-
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
-
Smith J.S., Brachmann C.B., Celic I., Kenna M.A., Muhammad S., Starai V.J., Avalos J.L., Escalante-Semerena J.C., Grubmeyer C., Wolberger C., Boeke J.D. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA. 97:2000;6658-6663.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6658-6663
-
-
Smith, J.S.1
Brachmann, C.B.2
Celic, I.3
Kenna, M.A.4
Muhammad, S.5
Starai, V.J.6
Avalos, J.L.7
Escalante-Semerena, J.C.8
Grubmeyer, C.9
Wolberger, C.10
Boeke, J.D.11
-
25
-
-
0347457075
-
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
-
Starai V.J., Celic I., Cole R.N., Boeke J.D., Escalante-Semerena J.C. Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science. 298:2002;2390-2392.
-
(2002)
Science
, vol.298
, pp. 2390-2392
-
-
Starai, V.J.1
Celic, I.2
Cole, R.N.3
Boeke, J.D.4
Escalante-Semerena, J.C.5
-
26
-
-
0034687694
-
Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
Tanner K.G., Landry J., Sternglanz R., Denu J.M. Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc. Natl. Acad. Sci. USA. 97:2000;14178-14182.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landry, J.2
Sternglanz, R.3
Denu, J.M.4
-
27
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum H.A., Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature. 410:2001;227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
28
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 107:2001;149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
29
-
-
0037421847
-
Structure and catalytic mechansim of human histone methyltransferase SET7/9
-
Xiao B., Jing C., Wilson J.R., Walker P.A., Vasisht N., Kelly G., Howell S., Taylor I.A., Blackburn G.M., Gamblin S.J. Structure and catalytic mechansim of human histone methyltransferase SET7/9. Nature. 421:2003;652-656.
-
(2003)
Nature
, vol.421
, pp. 652-656
-
-
Xiao, B.1
Jing, C.2
Wilson, J.R.3
Walker, P.A.4
Vasisht, N.5
Kelly, G.6
Howell, S.7
Taylor, I.A.8
Blackburn, G.M.9
Gamblin, S.J.10
-
30
-
-
0141618441
-
Structure and autoregulation of a full-length yeast homologue of Sir2
-
Zhao K., Chai X., Clements A., Marmorstein R. Structure and autoregulation of a full-length yeast homologue of Sir2. Nat. Struct. Biol. 10:2003;864-871.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 864-871
-
-
Zhao, K.1
Chai, X.2
Clements, A.3
Marmorstein, R.4
|