Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress

FASEB Journal

Volumn 17, Issue 6, 2003, Pages 668-674

  Tuo, Jingsheng ^a,c   Jaruga, Pawel ^b   Rodriguez, Henry ^b   Bohr, Vilhelm A ^a,b   Dizdaroglu, Miral ^a,b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

CS; Fibroblast cell line; Gamma irradiation

Indexed keywords

8 HYDROXYADENINE; 8 HYDROXYGUANINE; ADENINE DERIVATIVE; CELL EXTRACT; DNA BASE; ISOTOPE; UNCLASSIFIED DRUG; 8-HYDROXYADENINE; 8-HYDROXYGUANINE; ADENINE; DNA; DRUG DERIVATIVE; ENDONUCLEASE; EXONUCLEASE; GUANINE;

ADULT; ARTICLE; CELL MUTANT; CELL REGENERATION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; COCKAYNE SYNDROME; CONTROLLED STUDY; CSA GENE; CSB GENE; DNA DAMAGE; DNA REPAIR; FEMALE; FIBROBLAST; GENE; GENE FUNCTION; GENETIC CODE; HUMAN; HUMAN CELL; IONIZING RADIATION; LIQUID CHROMATOGRAPHY; MALE; NERVE DEGENERATION; OXIDATION; OXIDATIVE STRESS; PREMATURE AGING; PRIORITY JOURNAL; XERODERMA PIGMENTOSUM; CELL LINE; GENETICS; INFANT; METABOLISM; PATHOLOGY; PRESCHOOL CHILD; RADIATION EXPOSURE;

ADENINE; ADULT; CELL LINE; CHILD; CHILD, PRESCHOOL; COCKAYNE SYNDROME; DNA; DNA DAMAGE; DNA REPAIR; ENDONUCLEASES; EXONUCLEASES; FEMALE; GUANINE; HUMANS; INFANT; MALE; OXIDATIVE STRESS;

EID: 0141869885     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.02-0851com     Document Type: Article

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