Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G

Science

Volumn 275, Issue 5302, 1997, Pages 990-993

  Cooper, Priscilla K ^a   Nouspikel, Thierry ^b   Clarkson, Stuart G ^b   Leadon, Steven A ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE;

ARTICLE; CELL MUTANT; CELL STRAIN; CLINICAL FEATURE; COCKAYNE SYNDROME; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; EXCISION REPAIR; GENE MUTATION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; X IRRADIATION; XERODERMA PIGMENTOSUM;

COCKAYNE SYNDROME; DNA; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; GENETIC COMPLEMENTATION TEST; HUMANS; HYDROGEN PEROXIDE; MUTATION; NUCLEAR PROTEINS; OXIDATION-REDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 0031025997     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.275.5302.990     Document Type: Article

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30. We thank Z. Murthy for technical assistance and B. Dunphy for the XORC2 expression vector. Supported by NIH grants RO1GM44656 (to J.N.) and 1F32GM17980-01 (to J.W.).