-
3
-
-
0032555204
-
The elusive function of metallothioneins
-
Palmiter RD. The elusive function of metallothioneins. Proc Natl Acad Sci USA 1998;95(15):8428-8430.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.15
, pp. 8428-8430
-
-
Palmiter, R.D.1
-
4
-
-
0032953164
-
Metallothionein: An intracellular protein to protect against cadmium toxicity
-
Klaassen CD, Liu J, Choudhuri S. Metallothionein: An intracellular protein to protect against cadmium toxicity. Annu Rev Pharmacol Toxicol 1999;39:267-294.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 267-294
-
-
Klaassen, C.D.1
Liu, J.2
Choudhuri, S.3
-
5
-
-
0027414642
-
Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter
-
Radtke F, Heuchel R, Georgiev O, Hergersberg M, Gariglio M, Dembic Z, Schaffner W. Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter. EMBO J 1993;12(4):1355-1362.
-
(1993)
EMBO J
, vol.12
, Issue.4
, pp. 1355-1362
-
-
Radtke, F.1
Heuchel, R.2
Georgiev, O.3
Hergersberg, M.4
Gariglio, M.5
Dembic, Z.6
Schaffner, W.7
-
6
-
-
0028125990
-
Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1
-
Palmiter RD. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1. Proc Natl Acad Sci USA 1994;91(4):1219-1223.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.4
, pp. 1219-1223
-
-
Palmiter, R.D.1
-
7
-
-
3042739151
-
Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc
-
Bi Y, Palmiter RD, Wood KM, Ma Q. Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc. Biochem J 2004;380(Pt 3):695-703.
-
(2004)
Biochem J
, vol.380
, Issue.PART 3
, pp. 695-703
-
-
Bi, Y.1
Palmiter, R.D.2
Wood, K.M.3
Ma, Q.4
-
8
-
-
1842636876
-
Protection against zinc toxicity by metallothionein and zinc transporter 1
-
Palmiter RD. Protection against zinc toxicity by metallothionein and zinc transporter 1. Proc Natl Acad Sci USA 2004;101(14):4918-4923.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.14
, pp. 4918-4923
-
-
Palmiter, R.D.1
-
9
-
-
3042738968
-
Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver
-
Wang Y, Wimmer U, Lichtlen P, Inderbitzin D, Stieger B, Meier PJ, Hunziker L, Stallmach T, Forrer R, Rulicke T, et al. Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver. FASEB J 2004;18(10):1071-1079.
-
(2004)
FASEB J
, vol.18
, Issue.10
, pp. 1071-1079
-
-
Wang, Y.1
Wimmer, U.2
Lichtlen, P.3
Inderbitzin, D.4
Stieger, B.5
Meier, P.J.6
Hunziker, L.7
Stallmach, T.8
Forrer, R.9
Rulicke, T.10
-
10
-
-
0037413730
-
Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis
-
Egli D, Selvaraj A, Yepiskoposyan H, Zhang B, Hafen E, Georgiev O, Schaffner W. Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J 2003;22(1):100-108.
-
(2003)
EMBO J
, vol.22
, Issue.1
, pp. 100-108
-
-
Egli, D.1
Selvaraj, A.2
Yepiskoposyan, H.3
Zhang, B.4
Hafen, E.5
Georgiev, O.6
Schaffner, W.7
-
11
-
-
17444417126
-
Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes
-
Selvaraj A, Balamurugan K, Yepiskoposyan H, Zhou H, Egli D, Georgiev O, Thiele DJ, Schaffner W. Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. Genes Dev 2005;19(8):891-896.
-
(2005)
Genes Dev
, vol.19
, Issue.8
, pp. 891-896
-
-
Selvaraj, A.1
Balamurugan, K.2
Yepiskoposyan, H.3
Zhou, H.4
Egli, D.5
Georgiev, O.6
Thiele, D.J.7
Schaffner, W.8
-
12
-
-
33646935780
-
Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1
-
Gunes C, Heuchel R, Georgiev O, Muller KH, Lichtlen P, Bluthmann H, Marino S, Aguzzi A, Schaffner W. Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1. EMBO J 1998;17(10):2846-2854.
-
(1998)
EMBO J
, vol.17
, Issue.10
, pp. 2846-2854
-
-
Gunes, C.1
Heuchel, R.2
Georgiev, O.3
Muller, K.H.4
Lichtlen, P.5
Bluthmann, H.6
Marino, S.7
Aguzzi, A.8
Schaffner, W.9
-
13
-
-
0027204069
-
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse
-
Michalska AE, Choo KH. Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Natl Acad Sci USA 1993;90(17):8088-8092.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.17
, pp. 8088-8092
-
-
Michalska, A.E.1
Choo, K.H.2
-
14
-
-
0027955113
-
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium
-
Masters BA, Kelly EJ, Quaife CJ, Brinster RL, Palmiter RD. Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc Natl Acad Sci USA 1994;91(2):584-588.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.2
, pp. 584-588
-
-
Masters, B.A.1
Kelly, E.J.2
Quaife, C.J.3
Brinster, R.L.4
Palmiter, R.D.5
-
15
-
-
0029009956
-
Functional domains of the heavy metal-responsive transcription regulator MTF-1
-
Radtke F, Georgiev O, Muller HP, Brugnera E, Schaffner W. Functional domains of the heavy metal-responsive transcription regulator MTF-1. Nucleic Acids Res 1995;23(12):2277-2286.
-
(1995)
Nucleic Acids Res
, vol.23
, Issue.12
, pp. 2277-2286
-
-
Radtke, F.1
Georgiev, O.2
Muller, H.P.3
Brugnera, E.4
Schaffner, W.5
-
16
-
-
0035696187
-
Cellular zinc sensors: MTF-1 regulation of gene expression
-
Andrews GK. Cellular zinc sensors: MTF-1 regulation of gene expression. Biometals 2001;14(3-4):223-237.
-
(2001)
Biometals
, vol.14
, Issue.3-4
, pp. 223-237
-
-
Andrews, G.K.1
-
17
-
-
0035816670
-
Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signals
-
Saydam N, Georgiev O, Nakano MY, Greber UF, Schaffner W. Nucleo-cytoplasmic trafficking of metal-regulatory transcription factor 1 is regulated by diverse stress signals. J Biol Chem 2001;276(27):25487-25495.
-
(2001)
J Biol Chem
, vol.276
, Issue.27
, pp. 25487-25495
-
-
Saydam, N.1
Georgiev, O.2
Nakano, M.Y.3
Greber, U.F.4
Schaffner, W.5
-
18
-
-
0035834763
-
Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions
-
LaRochelle O, Gagne V, Charron J, Soh JW, Seguin C. Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions. J Biol Chem 2001;276(45):41879-41888.
-
(2001)
J Biol Chem
, vol.276
, Issue.45
, pp. 41879-41888
-
-
Larochelle, O.1
Gagne, V.2
Charron, J.3
Soh, J.W.4
Seguin, C.5
-
19
-
-
0037036433
-
Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: Identification of signal transduction cascades that control metal-inducible transcription
-
Saydam N, Adams TK, Steiner F, Schaffner W, Freedman JH. Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: Identification of signal transduction cascades that control metal-inducible transcription. J Biol Chem 2002;277(23):20438-20445.
-
(2002)
J Biol Chem
, vol.277
, Issue.23
, pp. 20438-20445
-
-
Saydam, N.1
Adams, T.K.2
Steiner, F.3
Schaffner, W.4
Freedman, J.H.5
-
20
-
-
4344716723
-
Gene- and cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1
-
Jiang H, Fu K, Andrews GK. Gene- and cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1. Biochem J 2004;382 (Pt 1):33-41.
-
(2004)
Biochem J
, vol.382
, Issue.PART 1
, pp. 33-41
-
-
Jiang, H.1
Fu, K.2
Andrews, G.K.3
-
21
-
-
0028948696
-
Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc
-
Palmiter RD, Findley SD. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J 1995;14(4):639-649.
-
(1995)
EMBO J
, vol.14
, Issue.4
, pp. 639-649
-
-
Palmiter, R.D.1
Findley, S.D.2
-
22
-
-
0034725042
-
Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide
-
Ma Q, Renzelli AJ, Baldwin KT, Antonini JM. Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide. J Biol Chem 2000;275(17):12676- 12683.
-
(2000)
J Biol Chem
, vol.275
, Issue.17
, pp. 12676-12683
-
-
Ma, Q.1
Renzelli, A.J.2
Baldwin, K.T.3
Antonini, J.M.4
-
23
-
-
0029963257
-
The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin
-
Ma Q, Whitlock JP Jr. The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol Cell Biol 1996;16(5):2144-2150.
-
(1996)
Mol Cell Biol
, vol.16
, Issue.5
, pp. 2144-2150
-
-
Ma, Q.1
Whitlock Jr., J.P.2
-
24
-
-
0030964708
-
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes
-
Kelly EJ, Sandgren EP, Brinster RL, Palmiter RD. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc Natl Acad Sci USA 1997;94(19):10045-10050.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.19
, pp. 10045-10050
-
-
Kelly, E.J.1
Sandgren, E.P.2
Brinster, R.L.3
Palmiter, R.D.4
-
25
-
-
0035202335
-
Putting its fingers on stressful situations: The heavy metal-regulatory transcription factor MTF-1
-
Lichtlen P, Schaffner W. Putting its fingers on stressful situations: The heavy metal-regulatory transcription factor MTF-1. Bioessays 2001;23(11):1010-1017.
-
(2001)
Bioessays
, vol.23
, Issue.11
, pp. 1010-1017
-
-
Lichtlen, P.1
Schaffner, W.2
-
26
-
-
0036805109
-
Activation of gene expression by metal-responsive signal transduction pathways
-
Adams TK, Saydam N, Steiner F, Schaffner W, Freedman JH. Activation of gene expression by metal-responsive signal transduction pathways. Environ Health Perspect 2002;110 (Suppl 5):813-817.
-
(2002)
Environ Health Perspect
, vol.110
, Issue.SUPPL. 5
, pp. 813-817
-
-
Adams, T.K.1
Saydam, N.2
Steiner, F.3
Schaffner, W.4
Freedman, J.H.5
-
27
-
-
0242637400
-
2 in vitro is modulated by metallothionein
-
2 in vitro is modulated by metallothionein. Mol Cell Biol 2003;23(23):8471-8485.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.23
, pp. 8471-8485
-
-
Zhang, B.1
Georgiev, O.2
Hagmann, M.3
Gunes, C.4
Cramer, M.5
Faller, P.6
Vasak, M.7
Schaffner, W.8
-
28
-
-
0042858186
-
Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1
-
Saydam N, Steiner F, Georgiev O, Schaffner W. Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1. J Biol Chem 2003;278(34):31879-31883.
-
(2003)
J Biol Chem
, vol.278
, Issue.34
, pp. 31879-31883
-
-
Saydam, N.1
Steiner, F.2
Georgiev, O.3
Schaffner, W.4
-
29
-
-
0037102576
-
Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho-dioxin- inducible poly(ADP-ribose) polymerase: Role of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator transcription activation domains and a labile transcription repressor
-
Ma Q. Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho- dioxin-inducible poly(ADP-ribose) polymerase: Role of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator transcription activation domains and a labile transcription repressor. Arch Biochem Biophys 2002;404(2):309-316.
-
(2002)
Arch Biochem Biophys
, vol.404
, Issue.2
, pp. 309-316
-
-
Ma, Q.1
-
30
-
-
0034708774
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activation and DNA binding of AhR
-
Ma Q, Baldwin KT. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activation and DNA binding of AhR. J Biol Chem 2000;275(12):8432-8438.
-
(2000)
J Biol Chem
, vol.275
, Issue.12
, pp. 8432-8438
-
-
Ma, Q.1
Baldwin, K.T.2
|