-
1
-
-
0025154985
-
Regulation of metallothionein gene expression
-
Andrews, G. K. Regulation of metallothionein gene expression. Prog. Food Nutr. Sci., 14: 193-258, 1990.
-
(1990)
Prog. Food Nutr. Sci.
, vol.14
, pp. 193-258
-
-
Andrews, G.K.1
-
2
-
-
0028358324
-
The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression
-
Heuchel, R., Radtke, F., Georgiev, O., Stark, G., Aguet, M., and Schaffner, W. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J., 13: 2870-2875, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 2870-2875
-
-
Heuchel, R.1
Radtke, F.2
Georgiev, O.3
Stark, G.4
Aguet, M.5
Schaffner, W.6
-
3
-
-
0030941965
-
Activation of the chicken metallothionein promoter by metals and oxidative stress in cultured cells and transgenic mice
-
Dalton, T., Paria, B. C., Fernando, L. P., Huet-Hudson, Y. M., Dey, S. K., and Andrews, G. K. Activation of the chicken metallothionein promoter by metals and oxidative stress in cultured cells and transgenic mice. Comp. Biochem. Physiol., 116B: 75-86, 1997.
-
(1997)
Comp. Biochem. Physiol.
, vol.116 B
, pp. 75-86
-
-
Dalton, T.1
Paria, B.C.2
Fernando, L.P.3
Huet-Hudson, Y.M.4
Dey, S.K.5
Andrews, G.K.6
-
4
-
-
0028987879
-
Metallothioneins and cell death by anticancer drugs
-
Lazo, J. S., and Pitt, B. R. Metallothioneins and cell death by anticancer drugs. Annu. Rev. Pharmacol. Toxicol., 35: 635-653, 1995.
-
(1995)
Annu. Rev. Pharmacol. Toxicol.
, vol.35
, pp. 635-653
-
-
Lazo, J.S.1
Pitt, B.R.2
-
5
-
-
0029074495
-
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide
-
Schwartz, M. A., Lazo, J. S., Yalowich, W. P., Allen, W. P., Whitmore, M., Bergonia, H. A., Tzeng, E., Billiar, T. R., Robbins, P. D., and Lancaster, J. R. Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide. Proc. Natl. Acad. Sci. USA, 92: 4452-4456, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4452-4456
-
-
Schwartz, M.A.1
Lazo, J.S.2
Yalowich, W.P.3
Allen, W.P.4
Whitmore, M.5
Bergonia, H.A.6
Tzeng, E.7
Billiar, T.R.8
Robbins, P.D.9
Lancaster, J.R.10
-
6
-
-
0030711622
-
Metallothionein accretion in human hepatic cells is linked to cellular proliferation
-
Studer, R., Vogt, C. P., Cavigelli, M., Hunziker, P. E., and Kagi, H. R. Metallothionein accretion in human hepatic cells is linked to cellular proliferation. Biochem. J., 328: 63-67, 1997.
-
(1997)
Biochem. J.
, vol.328
, pp. 63-67
-
-
Studer, R.1
Vogt, C.P.2
Cavigelli, M.3
Hunziker, P.E.4
Kagi, H.R.5
-
7
-
-
0028836796
-
Cell cycle regulation of metallothionein in human colonic cancer cells
-
Nagel, W. W., and Vallee, B. L. Cell cycle regulation of metallothionein in human colonic cancer cells. Proc. Natl. Acad. Sci. USA, 92: 579-583, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 579-583
-
-
Nagel, W.W.1
Vallee, B.L.2
-
8
-
-
0031133179
-
Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells
-
Abdel-Mageed, A., and Agrawal, K. C. Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells Cancer Gene Ther., 4: 199-207, 1997.
-
(1997)
Cancer Gene Ther.
, vol.4
, pp. 199-207
-
-
Abdel-Mageed, A.1
Agrawal, K.C.2
-
9
-
-
0030799592
-
Enhanced apoptosis in metallothionein null cells
-
Kondo, Y., Rusnak, J. M., Hoyt, D. G., Settineri, C. E., Pitt, B. R., and Lazo, J. S. Enhanced apoptosis in metallothionein null cells. Mol. Pharmacol., 52: 195-201, 1997.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 195-201
-
-
Kondo, Y.1
Rusnak, J.M.2
Hoyt, D.G.3
Settineri, C.E.4
Pitt, B.R.5
Lazo, J.S.6
-
10
-
-
0032101104
-
Activation of nuclear factor κ B: Potential role in metallothionein-mediated mitogenic response
-
Abdel-Mageed, A. B., and Agrawal, K. C. Activation of nuclear factor κ B: potential role in metallothionein-mediated mitogenic response. Cancer Res., 58: 2335-2338, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 2335-2338
-
-
Abdel-Mageed, A.B.1
Agrawal, K.C.2
-
11
-
-
0030983989
-
Significance of metallothionein overexpression in human tumors
-
Jasani, B., and Schmid, K. W. Significance of metallothionein overexpression in human tumors. Histopathology, 31: 211-214, 1997.
-
(1997)
Histopathology
, vol.31
, pp. 211-214
-
-
Jasani, B.1
Schmid, K.W.2
-
12
-
-
0031435182
-
Metallothionein expression in prostatic carcinoma: Correlation with Gleason grade, pathologic stage. DNA content and serum level of prostate-specific antigen
-
Moussa, M., Kloth, D., Peers, G., Cherian, M. G., Frei, J. V., and Chin, J. L. Metallothionein expression in prostatic carcinoma: correlation with Gleason grade, pathologic stage. DNA content and serum level of prostate-specific antigen. Clin. Invest. Med., 20: 371-380, 1997.
-
(1997)
Clin. Invest. Med.
, vol.20
, pp. 371-380
-
-
Moussa, M.1
Kloth, D.2
Peers, G.3
Cherian, M.G.4
Frei, J.V.5
Chin, J.L.6
-
13
-
-
33646935780
-
Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-i
-
Gunes, C., Heuchel, R., Georgiev, O., Muller, K. H., Lichtlen, P., Bluthmann, H., Marino, S., Aguzzi, A., and Schaffner, W. Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-i. EMBO J., 17: 2846-2854, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 2846-2854
-
-
Gunes, C.1
Heuchel, R.2
Georgiev, O.3
Muller, K.H.4
Lichtlen, P.5
Bluthmann, H.6
Marino, S.7
Aguzzi, A.8
Schaffner, W.9
-
14
-
-
0344212890
-
Glutathione deficency produced by inhibition of its synthesis and its reversal: Applications in research and therapy
-
Meister, A. Glutathione deficency produced by inhibition of its synthesis and its reversal: applications in research and therapy. Cancer Res., 54: 3082-3087, 1991.
-
(1991)
Cancer Res.
, vol.54
, pp. 3082-3087
-
-
Meister, A.1
-
15
-
-
0027355372
-
Regulation of human and yeast metallothionein gene transcription by heavy metal ions
-
Skroch, P., Buchman, C., and Karin, M. Regulation of human and yeast metallothionein gene transcription by heavy metal ions. Prog. Clin. Biol. Res., 380: 113-128, 1995.
-
(1995)
Prog. Clin. Biol. Res.
, vol.380
, pp. 113-128
-
-
Skroch, P.1
Buchman, C.2
Karin, M.3
-
16
-
-
0028846036
-
Functional analysis of the human metallothionein-IG gene
-
Samson, S. L-A., Paramchuk, W. J., Shworak, N. W., and Gedamu, L. Functional analysis of the human metallothionein-IG gene. J. Biol. Chem., 270: 25194-25199, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25194-25199
-
-
Samson, S.L.-A.1
Paramchuk, W.J.2
Shworak, N.W.3
Gedamu, L.4
-
17
-
-
0028077621
-
Metallothionein IIA is up-regulalcd by hypexia in human A431 squamous carcinoma cells
-
Murphy, B. J., Laderoute, K. R., Chin, R. J., and Sutherland, R. M. Metallothionein IIA is up-regulalcd by hypexia in human A431 squamous carcinoma cells. Cancer Res., 54: 5808-5810, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5808-5810
-
-
Murphy, B.J.1
Laderoute, K.R.2
Chin, R.J.3
Sutherland, R.M.4
-
18
-
-
0027414642
-
Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter
-
Radtke, F., Heuchel, R., Georgiev, O., Hergersberg, M., Gariglio, M., Dembic, Z., and Schaffner, W. Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter. EMBO J., 12: 1355-1362, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 1355-1362
-
-
Radtke, F.1
Heuchel, R.2
Georgiev, O.3
Hergersberg, M.4
Gariglio, M.5
Dembic, Z.6
Schaffner, W.7
-
19
-
-
0027938768
-
Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1
-
Brugnera, E., Georgiev, O., Radtke, F., Heuchel, R., Baker, E., Sutherland, G. R., and Schaffner, W. Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1. Nucleic Acids Res., 22: 3167-3173, 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3167-3173
-
-
Brugnera, E.1
Georgiev, O.2
Radtke, F.3
Heuchel, R.4
Baker, E.5
Sutherland, G.R.6
Schaffner, W.7
-
20
-
-
0030909001
-
Reversible activation of mouse metal response clement-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain
-
Dalton, T. P., Bittel, D., and Andrews, G. K. Reversible activation of mouse metal response clement-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain. Mol. Cell. Biol., 17: 2781-2789, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2781-2789
-
-
Dalton, T.P.1
Bittel, D.2
Andrews, G.K.3
-
21
-
-
0029910072
-
Oxidative stress activates metal-responsive transcription factor-1 binding activity
-
Dalton, T., Qingwen, L., Bittel, D., Liang, L., and Andrews, G. K. Oxidative stress activates metal-responsive transcription factor-1 binding activity. J. Biol Chem., 271: 26233-26241, 1996.
-
(1996)
J. Biol Chem.
, vol.271
, pp. 26233-26241
-
-
Dalton, T.1
Qingwen, L.2
Bittel, D.3
Liang, L.4
Andrews, G.K.5
-
22
-
-
0028593507
-
Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements
-
Dalton, T., Palmiter, R. D., and Andrews, G. K. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res., 22: 5016-5023, 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 5016-5023
-
-
Dalton, T.1
Palmiter, R.D.2
Andrews, G.K.3
-
23
-
-
0029985755
-
Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency
-
Dalton, T., Fu, K., Palmiter, R. D., and Andrews, G. K. Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency. J. Nutr., 126: 825-833, 1996.
-
(1996)
J. Nutr.
, vol.126
, pp. 825-833
-
-
Dalton, T.1
Fu, K.2
Palmiter, R.D.3
Andrews, G.K.4
-
24
-
-
0030964708
-
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes
-
Kelly, E. J., Sandgren, E. P., Brinster, R. L., and Palmiter, R. D. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc. Natl. Acad. Sci. USA, 94: 10045-10050, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10045-10050
-
-
Kelly, E.J.1
Sandgren, E.P.2
Brinster, R.L.3
Palmiter, R.D.4
-
25
-
-
0002377529
-
Oxygenation status of human tumors: A reappraisal using computerized pO2 histography
-
P. W. Vaupel, D. K. Kelleher, and M. Gunderoth (eds.). Tumor Oxygenation, Stuttgart, Jena. New York, Gustav Fischer Verlag
-
Vaupel, P. W., and Hockel, M. Oxygenation status of human tumors: a reappraisal using computerized pO2 histography. In: P. W. Vaupel, D. K. Kelleher, and M. Gunderoth (eds.). Funktionanalyze Biologischer Systeme. Tumor Oxygenation, pp. 219-232. Stuttgart, Jena. New York, Gustav Fischer Verlag, 1995.
-
(1995)
Funktionanalyze Biologischer Systeme
, pp. 219-232
-
-
Vaupel, P.W.1
Hockel, M.2
-
26
-
-
0023939652
-
Adenovirus EIA products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters
-
Lond.
-
Webster, K. A., Muscat, G. E. O., and Kedes, L. Adenovirus EIA products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters. Nature (Lond.), 332: 553-561, 1988.
-
(1988)
Nature
, vol.332
, pp. 553-561
-
-
Webster, K.A.1
Muscat, G.E.O.2
Kedes, L.3
-
27
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/ Akt signaling pathway in Ha-ras-transformcd cells through a hypoxia inducible factor-1 transcriptional element
-
Mazure, N. M., Chen, E. Y., Laderoute, K. R., and Giaccia, A. J. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/ Akt signaling pathway in Ha-ras-transformcd cells through a hypoxia inducible factor-1 transcriptional element. Blood, 90: 3322-3331, 1997.
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
Giaccia, A.J.4
-
28
-
-
0029022588
-
Metallothionein null cells have increased sensitivity to anticancer drugs
-
Kondo, Y., Woo, E. S., Michalska, A. E., Choo, A., and Lazo, J. S. Metallothionein null cells have increased sensitivity to anticancer drugs. Cancer Res., 55: 2021-2023, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2021-2023
-
-
Kondo, Y.1
Woo, E.S.2
Michalska, A.E.3
Choo, A.4
Lazo, J.S.5
-
29
-
-
0026758210
-
Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen
-
Laderoute, K. R., Grant, T. D., Murphy, B. J., and Sutherland, R. M. Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen. Int. J. Cancer. 52: 428-432, 1992.
-
(1992)
Int. J. Cancer.
, vol.52
, pp. 428-432
-
-
Laderoute, K.R.1
Grant, T.D.2
Murphy, B.J.3
Sutherland, R.M.4
-
30
-
-
0019932125
-
Human metallothionein genes: Primary structure of the metallothionein-II gene and a related processed gene
-
Lond.
-
Karin, M., and Richard, R. I. Human metallothionein genes: primary structure of the metallothionein-II gene and a related processed gene. Nature (Lond.), 299: 797-802, 1982.
-
(1982)
Nature
, vol.299
, pp. 797-802
-
-
Karin, M.1
Richard, R.I.2
-
31
-
-
0001723882
-
Transfection using DEAE-dextran
-
Gulick, T. Transfection using DEAE-dextran. Curr. Protocols Mol. Biol., 1: 9.2.1-9.2.10, 1997.
-
(1997)
Curr. Protocols Mol. Biol.
, vol.1
, pp. 921-9210
-
-
Gulick, T.1
-
32
-
-
0029117223
-
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
-
Ikeda, E., Achen, M. G., Breirer, G., and Risau, W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J. Biol. Chem., 270: 19761-19766, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19761-19766
-
-
Ikeda, E.1
Achen, M.G.2
Breirer, G.3
Risau, W.4
-
33
-
-
0029009956
-
Functional domains of the heavy metal-responsive transcription regulator MTF-1
-
Radtke, F., Georgiev, O., Muller, H-P., Brugnera, E., and Schaffner, W. Functional domains of the heavy metal-responsive transcription regulator MTF-1. Nucleic Acids Res., 23: 2277-2286, 1995.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2277-2286
-
-
Radtke, F.1
Georgiev, O.M.H.-P.2
Brugnera, E.3
Schaffner, W.4
-
34
-
-
0031057890
-
Hypoxia/reoxygenation stimulates jun kinase activity through redox signaling in cardiac myocytes
-
Laderoute, K. R., and Webster, K. A. Hypoxia/reoxygenation stimulates jun kinase activity through redox signaling in cardiac myocytes. Circ. Res., 80: 330-344, 1997.
-
(1997)
Circ. Res.
, vol.80
, pp. 330-344
-
-
Laderoute, K.R.1
Webster, K.A.2
-
35
-
-
0030042987
-
Physical and functional sensitivity of zinc finger transcription factors to redox change
-
Wu, X., Bishopric, N. H., Discher, D. J., Murphy, B. J., and Webster, K. W. Physical and functional sensitivity of zinc finger transcription factors to redox change. Mol. Cell. Biol., 16: 1035-1046, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1035-1046
-
-
Wu, X.1
Bishopric, N.H.2
Discher, D.J.3
Murphy, B.J.4
Webster, K.W.5
-
36
-
-
0024550092
-
Fine mapping of a mouse metallothionein gene metal response element
-
Culotta, V. C., and Hamer, D. H. Fine mapping of a mouse metallothionein gene metal response element. Mol. Cell. Biol., 9: 1376-1380, 1989.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1376-1380
-
-
Culotta, V.C.1
Hamer, D.H.2
-
37
-
-
0022410464
-
Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences
-
Lond.
-
Stuart, G. W., Searle, P. F., and Palmiter, R. D. Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences. Nature (Lond.), 317: 828-831, 1985.
-
(1985)
Nature
, vol.317
, pp. 828-831
-
-
Stuart, G.W.1
Searle, P.F.2
Palmiter, R.D.3
-
38
-
-
0032498230
-
The enhanceosome and transcriptional synergy
-
Carey, M. The enhanceosome and transcriptional synergy. Cell, 92: 5-8, 1998.
-
(1998)
Cell
, vol.92
, pp. 5-8
-
-
Carey, M.1
-
39
-
-
0031570296
-
Purification and characterization of a rat liver protein that recognizes CCAAT-homologous sequences of the metallothionein promoter and trans-activates this promoter
-
Aniskovitch, L. P., and Jacob, S. T. Purification and characterization of a rat liver protein that recognizes CCAAT-homologous sequences of the metallothionein promoter and trans-activates this promoter. Arch. Biochem. Biophys., 341: 337-346, 1997.
-
(1997)
Arch. Biochem. Biophys.
, vol.341
, pp. 337-346
-
-
Aniskovitch, L.P.1
Jacob, S.T.2
-
40
-
-
0032549517
-
The DNA-binding activity of MRE-binding transcription faclor-1 is activated in vivo and in in vitro by Zn, but not by other transition metals
-
Bittel, D., Dalton, T., Samson, S. L-A., Gedamu, L., and Andrews, G. K. The DNA-binding activity of MRE-binding transcription faclor-1 is activated in vivo and in in vitro by Zn, but not by other transition metals. J. Biol. Chem., 273: 7127-7133, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7127-7133
-
-
Bittel, D.1
Dalton, T.2
Samson, S.L.-A.3
Gedamu, L.4
Andrews, G.K.5
-
41
-
-
0028125990
-
Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor. MTF-1
-
Palmiter, R. D. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor. MTF-1. Proc. Natl. Acad. Sci. USA, 91: 1219-1223, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1219-1223
-
-
Palmiter, R.D.1
-
42
-
-
0030866226
-
Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway
-
Muller, J. M., Krauss, B., Kaltschmidt, C., Baeuerle, P. A., and Rupec, R. A. Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway. J. Biol. Chem., 272: 23435-23439, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23435-23439
-
-
Muller, J.M.1
Krauss, B.2
Kaltschmidt, C.3
Baeuerle, P.A.4
Rupec, R.A.5
-
43
-
-
0028129435
-
Regulation of c-jun expression during hypoxia and low glucose stress
-
Ausserer, W. A., Bourrat-Floeck, B., Green, C. J., and Sutherland, R. M. Regulation of c-jun expression during hypoxia and low glucose stress. Mol. Cell. Biol., 14: 5032-5042, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5032-5042
-
-
Ausserer, W.A.1
Bourrat-Floeck, B.2
Green, C.J.3
Sutherland, R.M.4
-
44
-
-
0031930069
-
dentification of a human VPF/VEGF 3′ untranslated region mediating hypoxia-induced mRNA stability
-
Claffey, K. P., Shih, S. C., Mullen, A., Dziennis, S., Cusick, J. L., Abrams, K. R., Lee, S. W., and Detmar, M. Identification of a human VPF/VEGF 3′ untranslated region mediating hypoxia-induced mRNA stability. Mol. Biol. Cell, 9: 469-481, 1998.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 469-481
-
-
Claffey, K.P.1
Shih, S.C.2
Mullen, A.3
Dziennis, S.4
Cusick, J.L.5
Abrams, K.R.6
Lee, S.W.7
Detmar M. I8
-
45
-
-
0027257482
-
Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes
-
Webster, K. A., Discher, D. J., and Bishopric, N. H. Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes. J. Biol. Chem., 268: 16852-16858, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 16852-16858
-
-
Webster, K.A.1
Discher, D.J.2
Bishopric, N.H.3
-
46
-
-
0030044039
-
Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
-
Levy, A. P., Levy, N. S., and Goldberg, M. A. Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J. Biol. Chem., 271: 2746-2753, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2746-2753
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
-
47
-
-
0026075610
-
Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
-
Semenza, G. L., Nejfelt, M. K., Chi, S. M., and Antonarakis, S. E. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc. Natl. Acad. Sci. USA, 88: 5680-5684, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5680-5684
-
-
Semenza, G.L.1
Nejfelt, M.K.2
Chi, S.M.3
Antonarakis, S.E.4
-
48
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza, G. L., Roth, P. H., Fang, H-M., and Wang, G. L. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem., 269: 23757-23763, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.-M.3
Wang, G.L.4
-
49
-
-
0025885693
-
Functional analysis of an oxygen-regulated transcriptional enhancer lying 3′ to the mouse erythropoietin gene
-
Pugh, C. W., Tan, C. C., Jones, R. W., and Ratcliffe, P. J. Functional analysis of an oxygen-regulated transcriptional enhancer lying 3′ to the mouse erythropoietin gene. Proc. Natl. Acad. Sci. USA, 88: 10553-10557, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10553-10557
-
-
Pugh, C.W.1
Tan, C.C.2
Jones, R.W.3
Ratcliffe, P.J.4
-
50
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and laclate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
-
Firth, J. D., Ebert, B. L., Pugh, C. W., and Ratcliffe, P. J. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and laclate dehydrogenase A genes: similarities with the erythropoietin 3′ enhancer. Proc. Natl. Acad. Sci. USA, 91: 6496-6500, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
51
-
-
0039529939
-
Hypoxia causes the activation of NF-κB through the phosphorylation of IκB on tyrosine residues
-
Koong, A. C., Chen, E. Y., and Giaccia, A. J. Hypoxia causes the activation of NF-κB through the phosphorylation of IκB on tyrosine residues. Cancer Res., 54: 1-6, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1-6
-
-
Koong, A.C.1
Chen, E.Y.2
Giaccia, A.J.3
-
52
-
-
0028110809
-
Hypoxia induces the accumulation of p53 protein but the activation of a G1 phase checkpoint by low oxygen conditions is independent of p53 status
-
Graeber, T., Koong, A. C., and Giaccia, A. J. Hypoxia induces the accumulation of p53 protein but the activation of a G1 phase checkpoint by low oxygen conditions is independent of p53 status. Mol. Cell. Biol., 14: 6264-6277, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6264-6277
-
-
Graeber, T.1
Koong, A.C.2
Giaccia, A.J.3
-
53
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Lond.
-
Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., and Giaccia, A. J. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature (Lond.), 379: 88-91, 1996.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
54
-
-
0027936404
-
Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia
-
Yao, K-S., Xanthoudakis, S., Curran, T., and O'Dwyer, P. J. Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Mol. Cell. Biol., 14: 5997-6003, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5997-6003
-
-
Yao, K.-S.1
Xanthoudakis, S.2
Curran, T.3
O'Dwyer, P.J.4
-
55
-
-
0031658790
-
The redox-sensitive human antioxidant responsive element induces gene expression under low oxygen conditions
-
Lond.
-
Waleh, N. S., Calaoagan, J., Murphy, B. J., Knapp, A. M., Sutherland, R. M., and Laderoute, K. L. The redox-sensitive human antioxidant responsive element induces gene expression under low oxygen conditions. Carcinogenesis (Lond.), 19: 1333-1337, 1998.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1333-1337
-
-
Waleh, N.S.1
Calaoagan, J.2
Murphy, B.J.3
Knapp, A.M.4
Sutherland, R.M.5
Laderoute, K.L.6
-
56
-
-
15444342958
-
Cellular and developmental control of oxygen homeostasis by hypoxia-inducible factor 1α
-
Iyer, N. V., Kotch, L., E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., Gassmann, J. D., Gearhart, J. D., Lawler, A. M., and Yu, A. Y. Cellular and developmental control of oxygen homeostasis by hypoxia-inducible factor 1α. Genes Dev., 12: 149-162, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, J.D.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
-
57
-
-
0030067857
-
Tumor hypoxia and heterogeneity: Challenges and opportunities for the future
-
Sutherland, R. M., Ausserer, W. A., Murphy, B. J., and Laderoute, K. R. Tumor hypoxia and heterogeneity: challenges and opportunities for the future. Semin. Radiat. Oncol., 6: 59-70, 1996.
-
(1996)
Semin. Radiat. Oncol.
, vol.6
, pp. 59-70
-
-
Sutherland, R.M.1
Ausserer, W.A.2
Murphy, B.J.3
Laderoute, K.R.4
-
58
-
-
0030067856
-
Hypoxic stress proteins: Survival of the fittest
-
Giaccia, A. J. Hypoxic stress proteins: survival of the fittest. Semin. Radiat. Oncol., 6: 46-58, 1996.
-
(1996)
Semin. Radiat. Oncol.
, vol.6
, pp. 46-58
-
-
Giaccia, A.J.1
-
59
-
-
0028340352
-
Cytoplasmic metallothionein overexpression protects NIH3T3 cells from tert-butylhydroperxide toxicity
-
Schwartz, M. A., Lazo, J. S., Yalowich, J. C., Reylonds, I., Kagan, V. E., Tyurin, V., Kim, T-M., Watkins, S. C., and Pitt, B. R. Cytoplasmic metallothionein overexpression protects NIH3T3 cells from tert-butylhydroperxide toxicity. J. Biol. Chem., 269: 15238-15213, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15238-115213
-
-
Schwartz, M.A.1
Lazo, J.S.2
Yalowich, J.C.3
Reylonds, I.4
Kagan, V.E.5
Tyurin, V.6
Kim, T.-M.7
Watkins, S.C.8
Pitt, B.R.9
-
60
-
-
0028206173
-
Effects of hypoxia on detoxicating enzyme activity and expression in HT29 colon adenocarcinoma cells
-
O'Dwyer, P. J., Yao, K. S., Godwin, A. K., and Clayton, M. Effects of hypoxia on detoxicating enzyme activity and expression in HT29 colon adenocarcinoma cells. Cancer Res., 54: 3082-3087, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3082-3087
-
-
O'Dwyer, P.J.1
Yao, K.S.2
Godwin, A.K.3
Clayton, M.4
-
61
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis hinds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza, G. L., and Wang, G. L. A nuclear factor induced by hypoxia via de novo protein synthesis hinds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol., 12: 5447-5454, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
62
-
-
0029103274
-
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells: Identification of a 5′ enhancer
-
Liu, Y., Cox, S. R., Motita, T., and Kourembanas, S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells: identification of a 5′ enhancer. Circ. Res., 77: 638-640, 1995.
-
(1995)
Circ. Res.
, vol.77
, pp. 638-640
-
-
Liu, Y.1
Cox, S.R.2
Motita, T.3
Kourembanas, S.4
-
63
-
-
0029101515
-
Hypoxia regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements
-
Firth, J. D., Ebert, B. L., and Ratcliffe, P. J. Hypoxia regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements. J. Biol. Chem., 270: 21021-21027, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21021-21027
-
-
Firth, J.D.1
Ebert, B.L.2
Ratcliffe, P.J.3
|