Long-term engraftment of hepatocytes transplanted on biodegradable polymer sponges

Journal of Biomedical Materials Research

Volumn 37, Issue 3, 1997, Pages 413-420

  Mooney, David J ^a,b,d   Sano, Kaoru ^b   Matthias Kaufmann, P ^b   Majahod, Karen ^a   Schloo, Betsy ^c   Vacanti, Joseph P ^b   Langer, Robert ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c DEBORAH HEART AND LUNG CENTER   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Hepatocytes; Polylactic acid; Portal vein; Tissue engineering; Transplantation

Indexed keywords

BIODEGRADATION; BLOOD VESSELS; CELLS; ORGANIC POLYMERS; POROUS MATERIALS; TISSUE; TRANSPLANTATION (SURGICAL);

HEPATOCYTES; POLYLACTIC ACID;

IMPLANTS (SURGICAL);

POLYLACTIC ACID; POLYMER;

ANIMAL EXPERIMENT; ARTICLE; BIODEGRADATION; LIVER FAILURE; LIVER TRANSPLANTATION; NONHUMAN; POLYMERIZATION; PORTAL VEIN; RAT; SURGICAL APPROACH; VASCULARIZATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL SURVIVAL; CELL TRANSPLANTATION; GRAFT SURVIVAL; HEPATECTOMY; LACTIC ACID; LIVER; LIVER TRANSPLANTATION; POLYGLYCOLIC ACID; POLYMERS; POROSITY; PORTACAVAL SHUNT, SURGICAL; RATS; RATS, INBRED LEW;

EID: 0031555489     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(19971205)37:3<413::AID-JBM12>3.0.CO;2-C     Document Type: Article

References (25)

1. T. E. Starzl, A. J. Demetris, and D. Van Thiel, "Chronic liver failure: orthotopic liver transplantation," N Eng. J. Med., 321, 1014-1022 (1989).
2. Annual report of the U.S. scientific registry for organ transplantation and the organ procurement and transplant network, 1990, Richmond, VA, UNOS, and Bethesda, MD, the division of organ transplantation, Health Resources and Services Administration, PE59, 19.
3. American Liver Foundation, Vital Statistics of the United States, 1988, Vol. 2 (A).
4. J. de Ville De Goyet, "Split liver transplantation in Europe - 1988 to 1993," Transplantation, 59, 1371-6 1995.
5. T. H. Kim and J. P. Vacanti, "Tissue engineering of the liver," in Biomedical Engineering Handbook, J. Bronzino (ed.), CRC Press, Boca Raton, FL, 1995, pp. 1745-1753.
6. R. Langer and J. P. Vacanti, "Tissue engineering," Science, 260, 920-926 (1993).
7. J. W. Grisham and W. B. Coleman, "Neoformation of liver epithelial cells: progenitor cells, stem cells, and phenotypic transitions," Gastroenterology, 110, 1311-1313 (1996).
8. J. M. Wilson, M. Grossman, S. E. Raper, J. R. Baker, R. S. Newton, and J. G. Thoene, "Ex vivo gene therapy of familial hypercholesteremia," Human Gene Therapy, 3, 179-222 (1992).
9. K. Asonuma, J. C. Gilbert, J. E. Stein, T. Takeda, and J. P. Vacanti, "Quantitation of transplanted hepatic mass necessary to cure the Gunn rat model of hyperbilirubinemia," J. Ped. Surg., 27, 298-301 (1992).
10. D. J. Mooney, P. M. Kaufmann, K. Sano, K. M. McNamara, J. P. Vacanti, and R. Langer, "Transplantation of hepatocytes using porous biodegradable sponges," Transplant. Proc., 26, 3425-3426 (1994).
11. D. J. Mooney, S. Park, P. M. Kaufmann, K. Sano, K. McNamara, J. P. Vacanti, and R. Langer, "Biodegradable sponges for hepatocyte transplantation," J. Biomed. Mater. Res., 29, 959-966 (1995).
12. A. G. Mikos, A. J. Thorsen, L. A. Czerwonka, Y. Bao, and R. Langer, "Preparation and characterization of poly (L-lactic acid) foams," Polymer, 35, 1068-1077 (1994).
13. D. Mooney, L. Hansen, J. Vacanti, R. Langer, S. Farmer, and D. Ingber, "Switching from differentiation to growth in hepatocytes: control by extracellular matrix," J. Cell Phys., 151, 497-505 (1992).
14. S. Uyama, P. M. Kaufmann, T. Takeda, and J. P. Vacanti, "Delivery of a whole liver equivalent hepatic mass using polymer devices and hepatotrophic stimulation," Transplantation, 55, 932-935 (1993).
15. D. J. Mooney, P. M. Kaufman, K. Sano, S. P. Schwendeman, K. Majahod, B. Schloo, J. P. Vacanti, and R. Langer, "Localized delivery of epidermal growth factor improves the survival of transplanted hepatocytes," Biotech. Bioeng., 50, 422-429 (1996).
16. C. Ricordi, P. E. Lacy, M. P. Callery, P. W. Park, and M. W. Flye, "Trophic factors from pancreatic islets in combined hepatocyte-islet allografts enhance hepatocellular survival," Surgery, 105, 218-223 (1993).
17. G. Shiota, T. C. Wang, T. Nakamura, and E. V. Schmidt, "Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression," Hepatology, 19, 962-972 (1994).
18. C. K. Colton, "Implantable biohybrid artificial organs," Cell Transplant, 4, 415-436 (1995).
19. P. M. Kaufmann, K. Sano, S. Uyama, and J. P. Vacanti, "Heterotopic hepatocyte transplantation using three dimensional polymers. Evaluation of the stimulatory effects by portacaval shunt or islet cell co-transplantation," Transplant. Proc., 26, 3343-3345 (1994).
20. G. M. Higgins and R. M. Anderson, "Experimental pathology of the liver," Arch. Pathol., 12, 186-201 (1931).
21. V. Jaffe, H. Darby, A. Bishop, and H. J. Hodgson, "The growth of liver cells in the pancreas after intrasplenic implantation: the effects of portal perfusion," Int. J. Exp. Path., 72, 289-299 (1991).
22. J. W. Grisham, "Cellular proliferation in the liver," Recent Results Cancer Res., 17, 28-43 (1969).
23. N. Wright, and M. Alison, "The biology of epithelial cell populations," in The Liver, Oxford Press, 1984, pp. 880-980.
24. J. A. Rhim, "Replacement of diseased mouse liver by hepatic cell transplantation," Science, 263, 1149-1152 (1994).
25. L. B. Johnson, J. Aiken, D. Mooney, B. Schloo, L. Cima, R. Langer, and J. P. Vacanti. "The mesentery as a laminated bed for hepatocyte transplantation," Cell Transplant., 3, 273-281 (1994).