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Volumn 201, Issue 10, 2005, Pages 1591-1602

Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; INTERLEUKIN 2 RECEPTOR ALPHA; TETRAMER; VACCINE;

EID: 21144454780     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20042167     Document Type: Article
Times cited : (370)

References (48)
  • 1
    • 0036630358 scopus 로고    scopus 로고
    • The thymus and negative selection
    • Sprent, J., and H. Kishimoto. 2002. The thymus and negative selection. Immunol. Rev. 185:126-135.
    • (2002) Immunol. Rev. , vol.185 , pp. 126-135
    • Sprent, J.1    Kishimoto, H.2
  • 2
    • 0036360019 scopus 로고    scopus 로고
    • The enemy within: Keeping self-reactive T cells at bay in the periphery
    • Walker, L.S., and A.K. Abbas. 2002. The enemy within: keeping self-reactive T cells at bay in the periphery. Nat. Rev. Immunol. 2:11-19.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 11-19
    • Walker, L.S.1    Abbas, A.K.2
  • 3
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra, A., and P. Vieira. 2004. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10:801-805.
    • (2004) Nat. Med. , vol.10 , pp. 801-805
    • O'Garra, A.1    Vieira, P.2
  • 4
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll, D. 2003. Does the immune system see tumors as foreign or self? Annu. Rev. Immunol. 21:807-839.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 5
    • 0030633566 scopus 로고    scopus 로고
    • HER-2/neu protein: A target for antigen-specific immunotherapy of human cancer
    • Disis, M.L., and M.A. Cheever. 1997. HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer. Adv. Cancer Res. 71: 343-371.
    • (1997) Adv. Cancer Res. , vol.71 , pp. 343-371
    • Disis, M.L.1    Cheever, M.A.2
  • 6
    • 12944325331 scopus 로고    scopus 로고
    • A listing of human tumor antigens recognized by T cells: March 2004 update
    • Novellino, L., C. Castelli, and G. Parmiani. 2005. A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol. Immunother. 54:187-207.
    • (2005) Cancer Immunol. Immunother. , vol.54 , pp. 187-207
    • Novellino, L.1    Castelli, C.2    Parmiani, G.3
  • 7
    • 0035869571 scopus 로고    scopus 로고
    • CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen
    • Hernandez, J., A. Ko, and L.A. Sherman. 2001. CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen. J. Immunol. 166:3908-3914.
    • (2001) J. Immunol. , vol.166 , pp. 3908-3914
    • Hernandez, J.1    Ko, A.2    Sherman, L.A.3
  • 8
    • 0031963994 scopus 로고    scopus 로고
    • Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity
    • Morgan, D.J., H.T. Kreuwel, S. Fleck, H.I. Levitsky, D.M. Pardoll, and L.A. Sherman. 1998. Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity. J. Immunol. 160:643-651.
    • (1998) J. Immunol. , vol.160 , pp. 643-651
    • Morgan, D.J.1    Kreuwel, H.T.2    Fleck, S.3    Levitsky, H.I.4    Pardoll, D.M.5    Sherman, L.A.6
  • 9
    • 0028824098 scopus 로고
    • Low avidity recognition of self-antigen by T cells permits escape from central tolerance
    • Liu, G.Y., P.J. Fairchild, R.M. Smith, J.R. Prowle, D. Kioussis, and D.C. Wraith. 1995. Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity. 3:407-415.
    • (1995) Immunity , vol.3 , pp. 407-415
    • Liu, G.Y.1    Fairchild, P.J.2    Smith, R.M.3    Prowle, J.R.4    Kioussis, D.5    Wraith, D.C.6
  • 10
    • 0029007485 scopus 로고
    • Intrathymic and extrathymic clonal deletion of T cells
    • Sprent, J., and S.R. Webb. 1995. Intrathymic and extrathymic clonal deletion of T cells. Curr. Opin. Immunol. 7:196-205.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 196-205
    • Sprent, J.1    Webb, S.R.2
  • 13
    • 0035478689 scopus 로고    scopus 로고
    • Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands
    • De Visser, K.E., T.A. Cordaro, H.W. Kessels, F.H. Tirion, T.N. Schumacher, and A.M. Kruisbeek, 2001. Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands. J. Immunol. 167:3818-3828.
    • (2001) J. Immunol. , vol.167 , pp. 3818-3828
    • De Visser, K.E.1    Cordaro, T.A.2    Kessels, H.W.3    Tirion, F.H.4    Schumacher, T.N.5    Kruisbeek, A.M.6
  • 14
    • 0033588894 scopus 로고    scopus 로고
    • Studying cancer in the mouse
    • Klausner, R.D. 1999. Studying cancer in the mouse. Oncogens. 20;18: 5249-5252.
    • (1999) Oncogens , vol.20 , Issue.18 , pp. 5249-5252
    • Klausner, R.D.1
  • 15
    • 0026472124 scopus 로고
    • Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
    • Guy, C.T., M.A. Webster, M. Schaller, T.J. Parsons, R.D. Cardiff, and W.J. Muller. 1992. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc. Natl. Acad. Sci. USA. 89:10578-10582.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10578-10582
    • Guy, C.T.1    Webster, M.A.2    Schaller, M.3    Parsons, T.J.4    Cardiff, R.D.5    Muller, W.J.6
  • 17
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • Machiels, J.P., R.T. Reilly, L.A. Emens, A.M. Ercolini, R.Y. Lei, D. Weintraub, F.I. Okoye, and E.M. Jaffee. 2001. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage- colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 61:3689-3697.
    • (2001) Cancer Res. , vol.61 , pp. 3689-3697
    • Machiels, J.P.1    Reilly, R.T.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6    Okoye, F.I.7    Jaffee, E.M.8
  • 18
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North, R.J. 1982. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J. Exp. Med. 155:1063-1074.
    • (1982) J. Exp. Med. , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 22
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 23
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 24
    • 0037446542 scopus 로고    scopus 로고
    • Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice
    • Ercolini, A.M., J.P. Machiels, Y.C. Chen, J.E. Slansky, M. Giedlen, R.T. Reilly, and E.M. Jaffee. 2003. Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice. J. Immunol. 170:4273-4280.
    • (2003) J. Immunol. , vol.170 , pp. 4273-4280
    • Ercolini, A.M.1    Machiels, J.P.2    Chen, Y.C.3    Slansky, J.E.4    Giedlen, M.5    Reilly, R.T.6    Jaffee, E.M.7
  • 26
    • 0033118739 scopus 로고    scopus 로고
    • A kinetic basis for T cell receptor repertoire selection during an immune response
    • Savage, P.A., J.J. Boniface, and M.M. Davis. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity. 10:485-492.
    • (1999) Immunity , vol.10 , pp. 485-492
    • Savage, P.A.1    Boniface, J.J.2    Davis, M.M.3
  • 27
    • 0035451399 scopus 로고    scopus 로고
    • Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: Correlation with CD8αβ versus CD8αα expression
    • Cawthon, A.G., H. Lu, and M. Alexander-Miller. 2001. Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8αβ versus CD8αα expression. J. Immunol. 167:2577-2584.
    • (2001) J. Immunol. , vol.167 , pp. 2577-2584
    • Cawthon, A.G.1    Lu, H.2    Alexander-Miller, M.3
  • 29
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka, S., I. Tawara, J. Shimizu, S. Sakaguchi, T. Fujita, and E. Nakayama. 1999. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 59:3128-3133.
    • (1999) Cancer Res. , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 31
    • 1642316449 scopus 로고    scopus 로고
    • + T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity
    • + T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity. Eur. J. Immunol. 34:752-761.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 752-761
    • Lustgarten, J.1    Dominguez, A.L.2    Cuadros, C.3
  • 32
    • 0033557173 scopus 로고    scopus 로고
    • T cell affinity maturation by selective expansion during infection
    • Busch, D.H., and E.G.P. Am. 1999. T cell affinity maturation by selective expansion during infection. J. Exp. Med. 189:701-710.
    • (1999) J. Exp. Med. , vol.189 , pp. 701-710
    • Busch, D.H.1    Am, E.G.P.2
  • 33
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller, M.A., G.R. Leggatt, and J.A. Berzofsky. 1996. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc. Natl. Acad. Sci. USA. 93: 4102-4107.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4102-4107
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 36
    • 0033558363 scopus 로고    scopus 로고
    • Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers
    • Yee, C., P.A. Savage, P.P. Lee, M.M. Davis, and P.D. Greenberg. 1999. Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers. J. Immunol. 162: 2227-2234.
    • (1999) J. Immunol. , vol.162 , pp. 2227-2234
    • Yee, C.1    Savage, P.A.2    Lee, P.P.3    Davis, M.M.4    Greenberg, P.D.5
  • 37
    • 0036644333 scopus 로고    scopus 로고
    • Anti-melanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity
    • Yang, S., G.P. Linette, S. Longerich, and F.G. Haluska. 2002. Anti-melanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J. Immunol. 169:531-539.
    • (2002) J. Immunol. , vol.169 , pp. 531-539
    • Yang, S.1    Linette, G.P.2    Longerich, S.3    Haluska, F.G.4
  • 38
    • 0033556322 scopus 로고    scopus 로고
    • High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    • Zeh, H.J., III, D. Perry-Lalley, M.E. Dudley, S.A. Rosenberg, and J.C. Yang. 1999. High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy. J. Immunol. 162:989-994.
    • (1999) J. Immunol. , vol.162 , pp. 989-994
    • Zeh III, H.J.1    Perry-Lalley, D.2    Dudley, M.E.3    Rosenberg, S.A.4    Yang, J.C.5
  • 40
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • Yang, Y., C.T. Huang, X. Huang, and D.M. Pardoll. 2004. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat. Immunol. 5:508-515.
    • (2004) Nat. Immunol. , vol.5 , pp. 508-515
    • Yang, Y.1    Huang, C.T.2    Huang, X.3    Pardoll, D.M.4
  • 42
    • 0343938862 scopus 로고    scopus 로고
    • The use of HLA A2.1/p53 peptide tetramers to visualize the impact of self tolerance on the TCR repertoire
    • Hernandez, J., P.P. Lee, M.M. Davis, and L.A. Sherman. 2000. The use of HLA A2.1/p53 peptide tetramers to visualize the impact of self tolerance on the TCR repertoire. J. Immunol. 164:596-602.
    • (2000) J. Immunol. , vol.164 , pp. 596-602
    • Hernandez, J.1    Lee, P.P.2    Davis, M.M.3    Sherman, L.A.4
  • 43
    • 0034985966 scopus 로고    scopus 로고
    • Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining
    • Derby, M.A., J. Wang, D.H. Margulies, and J.A. Berzofsky. 2001. Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining. Int. Immunol. 13:817-824.
    • (2001) Int. Immunol. , vol.13 , pp. 817-824
    • Derby, M.A.1    Wang, J.2    Margulies, D.H.3    Berzofsky, J.A.4
  • 44
    • 17944367867 scopus 로고    scopus 로고
    • Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life
    • Rubio-Godoy, V., V. Dutoit, D. Rimoldi, D. Lienard, F. Lejeune, D. Speiser, P. Guillaume, J.C. Cerottini, P. Romero, and D. Valmori. 2001. Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life. Proc. Natl. Acad. Sci. USA. 98:10302-10307.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10302-10307
    • Rubio-Godoy, V.1    Dutoit, V.2    Rimoldi, D.3    Lienard, D.4    Lejeune, F.5    Speiser, D.6    Guillaume, P.7    Cerottini, J.C.8    Romero, P.9    Valmori, D.10
  • 46
    • 0032543235 scopus 로고    scopus 로고
    • Cross-tolerance: A pathway for inducing tolerance to peripheral tissue antigens
    • Heath, W.R., C. Kurts, J.F. Miller, and F.R. Carbone. 1998. Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens. J. Exp. Med. 187:1549-1553.
    • (1998) J. Exp. Med. , vol.187 , pp. 1549-1553
    • Heath, W.R.1    Kurts, C.2    Miller, J.F.3    Carbone, F.R.4


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