Therapeutic targeting of the survivin pathway in cancer: Initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis

Clinical Cancer Research

Volumn 9, Issue 7, 2003, Pages 2683-2692

  Blanc Brude, Olivier P ^a,b   Mesri, Mehdi ^a,c   Wall, Nathan R ^a   Plescia, Janet ^a   Dohi, Takehiko ^a   Altieri, Dario C ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HÔPITAL LARIBOISIÈRE   (France)

^c CURAGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 3; CASPASE 7; CASPASE 9; CD31 ANTIGEN; CERAMIDE; CYTOCHROME C; DNA FRAGMENT; GREEN FLUORESCENT PROTEIN; GROWTH FACTOR; SURVIVIN; THREONINE;

ADENOVIRUS; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CAPILLARY; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG TARGETING; EMBRYO CELL; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; FEMALE; FIBROBLAST; GENE MUTATION; GENETIC CODE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; KNOCKOUT MOUSE; MALIGNANT NEOPLASTIC DISEASE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MORPHOMETRICS; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; SKIN; STAINING; TARGET CELL; TUMOR GROWTH; TUMOR VASCULARIZATION; UMBILICAL VEIN; VIRUS INFECTION; VIRUS REPLICATION; WILD TYPE; XENOGRAFT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CAPILLARIES; CASPASE 3; CASPASE 7; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CYTOSOL; DNA FRAGMENTATION; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; HUMANS; IN SITU NICK-END LABELING; KINETICS; LUMINESCENT PROTEINS; MICE; MICE, SCID; MICROCIRCULATION; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOSIS; MUTATION; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; TIME FACTORS; UMBILICAL VEINS;

EID: 0037817310     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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