Nicotinamide nucleotide transhydrogenase: A link between insulin secretion, glucose metabolism and oxidative stress

Biochemical Society Transactions

Volumn 34, Issue 5, 2006, Pages 806-810

  Freeman, H ^a,b   Shimomura, K ^a   Cox, R D ^b   Ashcroft, F M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

cell; Glucose metabolism; Nicotinamide nucleotide transhydrogenase (Nnt); Oxidative stress; Reactive oxygen species; Type 2 diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; ETHYLNITROSOUREA; INSULIN; MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE;

ELECTRON TRANSPORT; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PANCREAS ISLET CELL; PANCREAS ISLET CELL TUMOR; PRIORITY JOURNAL; REVIEW;

ANIMALS; GLUCOSE; INSULIN; MICE; MICE, KNOCKOUT; MITOCHONDRIAL MEMBRANES; NADP TRANSHYDROGENASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 33751296548     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0340806     Document Type: Review

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