메뉴 건너뛰기




Volumn 285, Issue 3 29-3, 2003, Pages

Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells

Author keywords

Arteries; Bcl; Hypertension; Smad; Transforming growth factor

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; OSTEOGENIC PROTEIN 1; PROTEIN BCL 2; SMAD PROTEIN;

EID: 17944386754     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00284.2002     Document Type: Article
Times cited : (221)

References (65)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adam JM and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326, 1998.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adam, J.M.1    Cory, S.2
  • 2
    • 0033521032 scopus 로고    scopus 로고
    • c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads
    • Akiyoshi S, Inoue H, Hanai J, Kusanagi K, Nemoto N, Miyazono K, and Kawabata M. c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads. J Biol Chem 274: 35269-35277, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 35269-35277
    • Akiyoshi, S.1    Inoue, H.2    Hanai, J.3    Kusanagi, K.4    Nemoto, N.5    Miyazono, K.6    Kawabata, M.7
  • 3
    • 0034727717 scopus 로고    scopus 로고
    • Primary pulmonary hypertension: A vascular biology and translational research "work in progress."
    • Archer S and Rich S. Primary pulmonary hypertension: a vascular biology and translational research "work in progress." Circulation 102: 2781-2791, 2000.
    • (2000) Circulation , vol.102 , pp. 2781-2791
    • Archer, S.1    Rich, S.2
  • 4
    • 0037046175 scopus 로고    scopus 로고
    • Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
    • Atkinson C, Stewart S, Upton P, Machado R, Thomson J, Trembath R, and Morrell N. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 105: 1672-1678, 2002.
    • (2002) Circulation , vol.105 , pp. 1672-1678
    • Atkinson, C.1    Stewart, S.2    Upton, P.3    Machado, R.4    Thomson, J.5    Trembath, R.6    Morrell, N.7
  • 5
    • 0034193390 scopus 로고    scopus 로고
    • BMP type II receptor is required for gastrulation and early development of mouse embryos
    • Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, and Miyazono K. BMP type II receptor is required for gastrulation and early development of mouse embryos. Dev Biol 221: 249-258, 2000.
    • (2000) Dev Biol , vol.221 , pp. 249-258
    • Beppu, H.1    Kawabata, M.2    Hamamoto, T.3    Chytil, A.4    Minowa, O.5    Noda, T.6    Miyazono, K.7
  • 6
    • 0032745819 scopus 로고    scopus 로고
    • Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: Association with changes in mitochondrial membrane potential
    • Cook SA, Sugden PH, and Clerk A. Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ Res 85: 940-949, 1999.
    • (1999) Circ Res , vol.85 , pp. 940-949
    • Cook, S.A.1    Sugden, P.H.2    Clerk, A.3
  • 7
    • 0034126770 scopus 로고    scopus 로고
    • Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor
    • Cowan KN, Heilbut A, Humpl T, Lam C, Ito S, and Rabinovitch M. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med 6: 698-702, 2000.
    • (2000) Nat Med , vol.6 , pp. 698-702
    • Cowan, K.N.1    Heilbut, A.2    Humpl, T.3    Lam, C.4    Ito, S.5    Rabinovitch, M.6
  • 8
    • 0033612184 scopus 로고    scopus 로고
    • Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis
    • Cowan KN, Jones PL, and Rahinovitch M. Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis. Circ Res 84: 1223-1233, 1999.
    • (1999) Circ Res , vol.84 , pp. 1223-1233
    • Cowan, K.N.1    Jones, P.L.2    Rahinovitch, M.3
  • 9
    • 0035721752 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
    • De Caestecker M and Meyrick B. Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension. Respir Res 2: 193-197, 2001.
    • (2001) Respir Res , vol.2 , pp. 193-197
    • De Caestecker, M.1    Meyrick, B.2
  • 11
    • 0034074899 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 (OP-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro
    • Dorai H, Vukicevic S, and Sampath TK. Bone morphogenetic protein-7 (OP-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol 184: 37-45, 2000.
    • (2000) J Cell Physiol , vol.184 , pp. 37-45
    • Dorai, H.1    Vukicevic, S.2    Sampath, T.K.3
  • 13
    • 0033522642 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinase II phophorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation
    • 2+/calmodulin-dependent kinase II phophorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation. J Biol Chem 274: 16168-16173, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 16168-16173
    • Feinmesser, R.L.1    Wicks, S.J.2    Taverner, C.J.3    Chantry, A.4
  • 15
    • 0031670961 scopus 로고    scopus 로고
    • Etiology and pathogenesis of primary pulmonary hypertension
    • Fishman AP. Etiology and pathogenesis of primary pulmonary hypertension. Chest 114 Suppl 3: 242S-247S, 1998.
    • (1998) Chest , vol.114 , Issue.SUPPL. 3
    • Fishman, A.P.1
  • 16
    • 0035970577 scopus 로고    scopus 로고
    • Gene expression patterns in the lungs of patients with primary pulmonary hypertension: A gene microarray analysis
    • Geraci M, Moore M, Gesell T, Yeager M, Alger L, Golpon H, Gao B, Loyd J, Tuder R, and Voelkel N. Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis. Circ Res 88: 555-562, 2001.
    • (2001) Circ Res , vol.88 , pp. 555-562
    • Geraci, M.1    Moore, M.2    Gesell, T.3    Yeager, M.4    Alger, L.5    Golpon, H.6    Gao, B.7    Loyd, J.8    Tuder, R.9    Voelkel, N.10
  • 17
    • 0034021776 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
    • Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI, and Knaus P. Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell 11: 1023-1035, 2000.
    • (2000) Mol Biol Cell , vol.11 , pp. 1023-1035
    • Gilboa, L.1    Nohe, A.2    Geissendorfer, T.3    Sebald, W.4    Henis, Y.I.5    Knaus, P.6
  • 18
    • 0031964859 scopus 로고    scopus 로고
    • Smad6 inhibits BMP/Smad 1 signaling by specifically competing with the Smad4 tumor suppressor
    • Hata A, Lagna G, Massague J, and Hemmati-Brivanlou A. Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev 12: 186-197, 1998.
    • (1998) Genes Dev , vol.12 , pp. 186-197
    • Hata, A.1    Lagna, G.2    Massague, J.3    Hemmati-Brivanlou, A.4
  • 19
    • 0034695506 scopus 로고    scopus 로고
    • OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
    • Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A, and Massague J. OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100: 229-240, 2000.
    • (2000) Cell , vol.100 , pp. 229-240
    • Hata, A.1    Seoane, J.2    Lagna, G.3    Montalvo, E.4    Hemmati-Brivanlou, A.5    Massague, J.6
  • 20
    • 0032526374 scopus 로고    scopus 로고
    • Apoptosis: Basic mechanisms and implications for cardiovascular disease
    • Haunstetter A and Izumo S. Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res 82: 1111-1129, 1998.
    • (1998) Circ Res , vol.82 , pp. 1111-1129
    • Haunstetter, A.1    Izumo, S.2
  • 21
    • 0030824575 scopus 로고    scopus 로고
    • Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2
    • He H, Lam M, McCormick TS, and Distelhorst CW. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J Cell Biol 138: 1219-1228, 1997.
    • (1997) J Cell Biol , vol.138 , pp. 1219-1228
    • He, H.1    Lam, M.2    McCormick, T.S.3    Distelhorst, C.W.4
  • 22
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, and ten Dijke P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390: 465-471, 1997.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 24
    • 0033531948 scopus 로고    scopus 로고
    • Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells
    • Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K, ten Dijke P, Sugino H, and Nishihara T. Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells. J Biol Chem 274: 13637-13642, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 13637-13642
    • Ishisaki, A.1    Yamato, K.2    Hashimoto, S.3    Nakao, A.4    Tamaki, K.5    Nonaka, K.6    Ten Dijke, P.7    Sugino, H.8    Nishihara, T.9
  • 25
    • 0032544594 scopus 로고    scopus 로고
    • Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells
    • Ishisaki A, Yamato K, Nakao A, Nonaka K, Ohguchi M, ten Dijke P, and Nishihara T. Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells. J Biol Chem 273: 24293-24296, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 24293-24296
    • Ishisaki, A.1    Yamato, K.2    Nakao, A.3    Nonaka, K.4    Ohguchi, M.5    Ten Dijke, P.6    Nishihara, T.7
  • 26
    • 0029022554 scopus 로고
    • Apoptosis in human atherosclerosis and restenosis
    • Isner JM, Kearney M, Bortman S, and Passeri J. Apoptosis in human atherosclerosis and restenosis. Circulation 91: 2703-2711, 1995.
    • (1995) Circulation , vol.91 , pp. 2703-2711
    • Isner, J.M.1    Kearney, M.2    Bortman, S.3    Passeri, J.4
  • 27
    • 0031561724 scopus 로고    scopus 로고
    • BMP7 null mutation in mice: Developmental defects in skeleton, kidney, and eye
    • Jena N, Martin-Seisdedos C, McCue P, and Croce CM. BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye. Exp Cell Res 230: 28-37, 1997.
    • (1997) Exp Cell Res , vol.230 , pp. 28-37
    • Jena, N.1    Martin-Seisdedos, C.2    McCue, P.3    Croce, C.M.4
  • 28
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, and Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136, 1997.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 29
    • 0034826931 scopus 로고    scopus 로고
    • Cooperativity of binding epitopes and receptor chains in the BMP/TGF-β superfamily
    • Knaus P and Sebald W. Cooperativity of binding epitopes and receptor chains in the BMP/TGF-β superfamily. J Biol Chem 382: 1189-1195, 2001.
    • (2001) J Biol Chem , vol.382 , pp. 1189-1195
    • Knaus, P.1    Sebald, W.2
  • 32
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension
    • Lane K, Machado R, Pauciulo M, Thomson J, Phillips J, Loyd J, Nichols W, and Trembath R. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. Nat Genet 26: 81-84, 2000.
    • (2000) Nat Genet , vol.26 , pp. 81-84
    • Lane, K.1    Machado, R.2    Pauciulo, M.3    Thomson, J.4    Phillips, J.5    Loyd, J.6    Nichols, W.7    Trembath, R.8
  • 33
    • 0033200361 scopus 로고    scopus 로고
    • The ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling
    • Luo K, Stroschein SL, Wang W, Chen D, Martens E, Zhou S, and Zhou Q. The ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling. Genes Dev 13: 2196-2206, 1999.
    • (1999) Genes Dev , vol.13 , pp. 2196-2206
    • Luo, K.1    Stroschein, S.L.2    Wang, W.3    Chen, D.4    Martens, E.5    Zhou, S.6    Zhou, Q.7
  • 35
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-β signaling
    • Massague J and Chen YG. Controlling TGF-β signaling. Genes Dev 14: 627-644, 2000.
    • (2000) Genes Dev , vol.14 , pp. 627-644
    • Massague, J.1    Chen, Y.G.2
  • 36
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-β/Smad signaling system
    • Maasague J and Wotton D. Transcriptional control by the TGF-β/Smad signaling system. EMBO J 19: 1745-1754, 2000.
    • (2000) EMBO J , vol.19 , pp. 1745-1754
    • Maasague, J.1    Wotton, D.2
  • 37
    • 0035032914 scopus 로고    scopus 로고
    • Divergence and convergence of TFG-β/BMP signaling
    • Miyazono K, Kusanagi K, and Inoue H. Divergence and convergence of TFG-β/BMP signaling. J Cell Physiol 187: 265-276, 2001.
    • (2001) J Cell Physiol , vol.187 , pp. 265-276
    • Miyazono, K.1    Kusanagi, K.2    Inoue, H.3
  • 40
    • 0035203755 scopus 로고    scopus 로고
    • Annexin V staining during reperfusion detects cardiomyocytes with unique properties
    • Narayan P, Mentzer R, and Lasley R. Annexin V staining during reperfusion detects cardiomyocytes with unique properties. Am J Physiol Heart Circ Physiol 281: H1931-H1937, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Narayan, P.1    Mentzer, R.2    Lasley, R.3
  • 41
    • 0035797529 scopus 로고    scopus 로고
    • Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in large kindred
    • Newman J, Wheeler L, Lane K, Loyd E, Gaddipati R, Phillips J, and Loyd J. Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in large kindred. N Engl J Med 345: 319-324, 2001.
    • (2001) N Engl J Med , vol.345 , pp. 319-324
    • Newman, J.1    Wheeler, L.2    Lane, K.3    Loyd, E.4    Gaddipati, R.5    Phillips, J.6    Loyd, J.7
  • 42
    • 0037085287 scopus 로고    scopus 로고
    • The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
    • Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis Y, and Knaus P. The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem 277: 5330-5338, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 5330-5338
    • Nohe, A.1    Hassel, S.2    Ehrlich, M.3    Neubauer, F.4    Sebald, W.5    Henis, Y.6    Knaus, P.7
  • 43
    • 0031671673 scopus 로고    scopus 로고
    • Elastase and the pathobiology of unexplained pulmonary hypertension
    • Rabinovitch M. Elastase and the pathobiology of unexplained pulmonary hypertension. Chest 114, Suppl 3: 213S-224S, 1998.
    • (1998) Chest , vol.114 , Issue.SUPPL. 3
    • Rabinovitch, M.1
  • 47
    • 0036299238 scopus 로고    scopus 로고
    • Apoptosis and proliferation of human peritoneal fibroblasts in response to hypoxia
    • Saed GM and Diamond MP. Apoptosis and proliferation of human peritoneal fibroblasts in response to hypoxia. Fertil Steril 78: 137-143, 2002.
    • (2002) Fertil Steril , vol.78 , pp. 137-143
    • Saed, G.M.1    Diamond, M.P.2
  • 48
    • 0035116044 scopus 로고    scopus 로고
    • Structural insights on Smad function in TGF-β signaling
    • Shi Y. Structural insights on Smad function in TGF-β signaling. Bioessays 23: 223-232, 2001.
    • (2001) Bioessays , vol.23 , pp. 223-232
    • Shi, Y.1
  • 50
    • 0030934358 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling
    • Stenmark KR and Mecham RP. Cellular and molecular mechanisms of pulmonary vascular remodeling. Annu Rev Physiol 59: 89-144, 1997.
    • (1997) Annu Rev Physiol , vol.59 , pp. 89-144
    • Stenmark, K.R.1    Mecham, R.P.2
  • 51
    • 0033607240 scopus 로고    scopus 로고
    • SnoN and Ski protooneoproteins are rapidly degraded in response to transforming growth factor beta signaling
    • Sun Y, Liu X, Ng-Eaton E, Lodish HF, and Weinberg RA. SnoN and Ski protooneoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci USA 96: 12442-12447, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12442-12447
    • Sun, Y.1    Liu, X.2    Ng-Eaton, E.3    Lodish, H.F.4    Weinberg, R.A.5
  • 53
    • 0033956131 scopus 로고    scopus 로고
    • Signaling inputs converge on nuclear effectors in TGF-β signaling
    • Ten Dijke P, Miyazono K, and Heldin CH. Signaling inputs converge on nuclear effectors in TGF-β signaling. Trends Biochem Sci 25: 64-70, 2002.
    • (2002) Trends Biochem Sci , vol.25 , pp. 64-70
    • Ten Dijke, P.1    Miyazono, K.2    Heldin, C.H.3
  • 54
    • 0036933503 scopus 로고    scopus 로고
    • Apoptosis in lung fibrosis and repair
    • Uhal BD. Apoptosis in lung fibrosis and repair. Chest 122, Suppl 6: 293S-298S, 2002.
    • (2002) Chest , vol.122 , Issue.SUPPL. 6
    • Uhal, B.D.1
  • 55
    • 0031260620 scopus 로고    scopus 로고
    • Cellular and molecular biology of vascular smooth muscle cells in pulmonary hypertension
    • Voelkel NF and Tuder RM. Cellular and molecular biology of vascular smooth muscle cells in pulmonary hypertension. Pul Pharmacol Ther 10: 231-241, 1997.
    • (1997) Pul Pharmacol Ther , vol.10 , pp. 231-241
    • Voelkel, N.F.1    Tuder, R.M.2
  • 56
    • 0035504887 scopus 로고    scopus 로고
    • Intracellular BMP signaling regulation in vertebrates: Pathway or network
    • Von Budnoff A and Cho KWY. Intracellular BMP signaling regulation in vertebrates: pathway or network. Dev Biol 239: 1-14, 2001.
    • (2001) Dev Biol , vol.239 , pp. 1-14
    • Von Budnoff, A.1    Cho, K.W.Y.2
  • 57
    • 0037403370 scopus 로고    scopus 로고
    • BMP-2 inhibits proliferation of human aortic smooth muscle cells via p21Cip1/Waf1
    • Wong GA, Tang V, El-Sabeawy F, and Weiss RH. BMP-2 inhibits proliferation of human aortic smooth muscle cells via p21Cip1/Waf1. Am J Physiol Endocrinol Metab 284: E972-E979, 2003.
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Wong, G.A.1    Tang, V.2    El-Sabeawy, F.3    Weiss, R.H.4
  • 58
    • 0036974081 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues
    • Wordinger RJ, Agarwal R, Talati M, Fuller J, Lambert W, and Clark AF. Expression of bone morphogenetic protein (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Mol Vis 8: 241-250, 2002.
    • (2002) Mol Vis , vol.8 , pp. 241-250
    • Wordinger, R.J.1    Agarwal, R.2    Talati, M.3    Fuller, J.4    Lambert, W.5    Clark, A.F.6
  • 59
    • 0033515620 scopus 로고    scopus 로고
    • A smad transcriptional corepressor
    • Wotton D, Lo RS, Lee S, and Massague J. A smad transcriptional corepressor. Cell 97: 29-39, 1999.
    • (1999) Cell , vol.97 , pp. 29-39
    • Wotton, D.1    Lo, R.S.2    Lee, S.3    Massague, J.4
  • 60
    • 0034680863 scopus 로고    scopus 로고
    • Critical role of SMADs and AP-1 complex in transforming growth factor-beta-dependent apoptosis
    • Yamamura Y, Hua X, Bergelson S, and Lodish HF. Critical role of SMADs and AP-1 complex in transforming growth factor-beta-dependent apoptosis. J Biol Chem 275: 36295-36302, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 36295-36302
    • Yamamura, Y.1    Hua, X.2    Bergelson, S.3    Lodish, H.F.4
  • 61
    • 0032192236 scopus 로고    scopus 로고
    • Induction of apoptosis by SMAD3 and down-regulation of SMAD3 expression in response to TGF-beta in human normal lung epithelial cells
    • Yanagisawa K, Osada H, Masuda A, Kondo M, Saito T, Yatabe Y, Takagi K, Takahashi T, and Takahashi T. Induction of apoptosis by SMAD3 and down-regulation of SMAD3 expression in response to TGF-beta in human normal lung epithelial cells. Oncogene 17: 1732-1747, 1998.
    • (1998) Oncogene , vol.17 , pp. 1732-1747
    • Yanagisawa, K.1    Osada, H.2    Masuda, A.3    Kondo, M.4    Saito, T.5    Yatabe, Y.6    Takagi, K.7    Takahashi, T.8    Takahashi, T.9
  • 65
    • 0031984518 scopus 로고    scopus 로고
    • Smad proteins physically interact with calmodulin
    • Zimmerman CM, Kariapper MS, and Mathews LS. Smad proteins physically interact with calmodulin. J Biol Chem 273: 677-680, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 677-680
    • Zimmerman, C.M.1    Kariapper, M.S.2    Mathews, L.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.