-
2
-
-
7044274454
-
Genome-scale profiling of gene expression in hepatocellular carcinoma: Classification, survival prediction, and identification of therapeutic targets
-
Lee JS, Thorgeirsson SS. Genome-scale profiling of gene expression in hepatocellular carcinoma: classification, survival prediction, and identification of therapeutic targets. Gastroenterology 2004; 127: S51-555
-
(2004)
Gastroenterology
, vol.127
-
-
Lee, J.S.1
Thorgeirsson, S.S.2
-
4
-
-
7044239399
-
Hepatocellular carcinoma: Current management and future trends
-
Carr BI. Hepatocellular carcinoma: current management and future trends. Gastroenterology 2004; 127: S218-S224
-
(2004)
Gastroenterology
, vol.127
-
-
Carr, B.I.1
-
5
-
-
0141718492
-
Combined interventional therapies of hepatocellular carcinoma
-
Qian J, Feng GS, Vogl T. Combined interventional therapies of hepatocellular carcinoma. World J Gastroenterol 2003; 9: 1885-1891
-
(2003)
World J Gastroenterol
, vol.9
, pp. 1885-1891
-
-
Qian, J.1
Feng, G.S.2
Vogl, T.3
-
6
-
-
3142696175
-
Gene therapy of liver diseases
-
Prieto J, Qian C, Hernandez-Alcoceba R, Gonzalez-Aseguinolaza G, Mazzolini G, Sangro B, Kramer MG. Gene therapy of liver diseases. Expert Opin Biol Ther 2004; 4: 1073-1091
-
(2004)
Expert Opin Biol Ther
, vol.4
, pp. 1073-1091
-
-
Prieto, J.1
Qian, C.2
Hernandez-Alcoceba, R.3
Gonzalez-Aseguinolaza, G.4
Mazzolini, G.5
Sangro, B.6
Kramer, M.G.7
-
7
-
-
0035522894
-
Two genetic hits (more or less) to cancer
-
Knudson AG. Two genetic hits (more or less) to cancer. Nat Rev Cancer 2001;1:157-162
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 157-162
-
-
Knudson, A.G.1
-
8
-
-
0842283424
-
Tumor-suppressing gene therapy
-
Fang B, Roth JA. Tumor-suppressing gene therapy. Cancer Biol Ther 2003; 2: S115-S121
-
(2003)
Cancer Biol Ther
, vol.2
-
-
Fang, B.1
Roth, J.A.2
-
9
-
-
14444267312
-
p53 gene therapy in a rat model of hepatocellular carcinoma: Intra-arterial delivery of a recombinant adenovirus
-
Anderson SC, Johnson DE, Harris MP, Engler H, Hancock W, Huang WM, Wills KN, Gregory RJ, Sutjipto S, Wen SF, Lofgren S, Shepard HM, Maneval DC. p53 gene therapy in a rat model of hepatocellular carcinoma: intra-arterial delivery of a recombinant adenovirus. Clin Cancer Res 1998; 4: 1649-1659
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1649-1659
-
-
Anderson, S.C.1
Johnson, D.E.2
Harris, M.P.3
Engler, H.4
Hancock, W.5
Huang, W.M.6
Wills, K.N.7
Gregory, R.J.8
Sutjipto, S.9
Wen, S.F.10
Lofgren, S.11
Shepard, H.M.12
Maneval, D.C.13
-
10
-
-
0034065509
-
Detection of adenovirus and initiation of apoptosis in hepatocellular carcinoma cells after Ad-p53 treatment
-
Mitry RR, Sarraf CE, Havlik R, Habib NA. Detection of adenovirus and initiation of apoptosis in hepatocellular carcinoma cells after Ad-p53 treatment. Hepatology 2000; 31: 885-889
-
(2000)
Hepatology
, vol.31
, pp. 885-889
-
-
Mitry, R.R.1
Sarraf, C.E.2
Havlik, R.3
Habib, N.A.4
-
11
-
-
0025732215
-
Mutational hotspot in the p53 gene in human hepatocellular carcinomas
-
Hsu IC, Metcalf RA, Sun T, Welsh JA, Wang NJ, Harris CC. Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 1991; 350: 427-428
-
(1991)
Nature
, vol.350
, pp. 427-428
-
-
Hsu, I.C.1
Metcalf, R.A.2
Sun, T.3
Welsh, J.A.4
Wang, N.J.5
Harris, C.C.6
-
13
-
-
3042609978
-
Manipulation of the tumor suppressor p53 for potentiating cancer therapy
-
Haupt S, Haupt Y. Manipulation of the tumor suppressor p53 for potentiating cancer therapy. Semin Cancer Biol 2004; 14: 244-252
-
(2004)
Semin Cancer Biol
, vol.14
, pp. 244-252
-
-
Haupt, S.1
Haupt, Y.2
-
14
-
-
24944454988
-
Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
-
Peng Z. Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 2005; 16: 1016-1027
-
(2005)
Hum Gene Ther
, vol.16
, pp. 1016-1027
-
-
Peng, Z.1
-
15
-
-
23944483437
-
Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
-
Deshayes S, Morris MC, Divita G, Heitz F. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell Mol Life Sci 2005; 62: 1839-1849
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 1839-1849
-
-
Deshayes, S.1
Morris, M.C.2
Divita, G.3
Heitz, F.4
-
16
-
-
0036320613
-
Gene therapy by intrahepatic and intratumoral trafficking of p53-VP22 induces regression of liver tumors
-
Zender L, Kock R, Eckhard M, Frericks B, Gosling T, Gebhardt T, Drobek S, Galanski M, Kuhnel F, Manns M, Kubicka S. Gene therapy by intrahepatic and intratumoral trafficking of p53-VP22 induces regression of liver tumors. Gastroenterology 2002; 123: 608-618
-
(2002)
Gastroenterology
, vol.123
, pp. 608-618
-
-
Zender, L.1
Kock, R.2
Eckhard, M.3
Frericks, B.4
Gosling, T.5
Gebhardt, T.6
Drobek, S.7
Galanski, M.8
Kuhnel, F.9
Manns, M.10
Kubicka, S.11
-
17
-
-
0030614944
-
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
-
Sandig V, Brand K, Herwig S, Lukas J, Bartek J, Strauss M. Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death. Nat Med 1997; 3: 313-319
-
(1997)
Nat Med
, vol.3
, pp. 313-319
-
-
Sandig, V.1
Brand, K.2
Herwig, S.3
Lukas, J.4
Bartek, J.5
Strauss, M.6
-
18
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, Harris CC, Herman JG. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet 2001; 28: 29-35
-
(2001)
Nat Genet
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
-
19
-
-
4444369081
-
Ras inhibition leads to transcriptional activation of p53 and down-regulation of Mdm2: Two mechanisms that cooperatively increase p53 function in colon cancer cells
-
Halaschek-Wiener J, Wacheck V, Kloog Y, Jansen B. Ras inhibition leads to transcriptional activation of p53 and down-regulation of Mdm2: two mechanisms that cooperatively increase p53 function in colon cancer cells. Cell Signal 2004; 16: 1319-1327
-
(2004)
Cell Signal
, vol.16
, pp. 1319-1327
-
-
Halaschek-Wiener, J.1
Wacheck, V.2
Kloog, Y.3
Jansen, B.4
-
20
-
-
33646564091
-
Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo
-
Cho-Rok J, Yoo J, Jang YJ, Kim S, Chu IS, Yeom YI, Choi JY, Im DS. Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo. Hepatology 2006; 43: 1042-1052
-
(2006)
Hepatology
, vol.43
, pp. 1042-1052
-
-
Cho-Rok, J.1
Yoo, J.2
Jang, Y.J.3
Kim, S.4
Chu, I.S.5
Yeom, Y.I.6
Choi, J.Y.7
Im, D.S.8
-
21
-
-
14544277627
-
Telomeres and telomerase: Their mechanisms of action and the effects of altering their functions
-
Blackburn EH. Telomeres and telomerase: their mechanisms of action and the effects of altering their functions. FEBS Lett 2005; 579: 859-862
-
(2005)
FEBS Lett
, vol.579
, pp. 859-862
-
-
Blackburn, E.H.1
-
22
-
-
0034775290
-
Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells
-
Saretzki G, Ludwig A, von Zglinicki T, Runnebaum IB. Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells, Cancer Gene Ther 2001; 8: 827-834
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 827-834
-
-
Saretzki, G.1
Ludwig, A.2
von Zglinicki, T.3
Runnebaum, I.B.4
-
23
-
-
0034200846
-
Telomeres and telomerase
-
Blackburn EH. Telomeres and telomerase. Keio J Med 2000; 49: 59-65
-
(2000)
Keio J Med
, vol.49
, pp. 59-65
-
-
Blackburn, E.H.1
-
24
-
-
1642430704
-
Antisense oligonucleotide-based therapeutics for cancer
-
Dean NM, Bennett CF. Antisense oligonucleotide-based therapeutics for cancer. Oncogene 2003; 22: 9087-9096
-
(2003)
Oncogene
, vol.22
, pp. 9087-9096
-
-
Dean, N.M.1
Bennett, C.F.2
-
25
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature 2004; 431: 371-378
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
26
-
-
6444245579
-
IGF-I: From diagnostic to triple-helix gene therapy of solid tumors
-
Trojan LA, Kopinski P, Wei MX, Ly A, Glogowska A, Czarny J, Shevelev A, Przewlocki R, Henin D, Trojan J. IGF-I: from diagnostic to triple-helix gene therapy of solid tumors. Acta Biochim Pol 2002; 49: 979-990
-
(2002)
Acta Biochim Pol
, vol.49
, pp. 979-990
-
-
Trojan, L.A.1
Kopinski, P.2
Wei, M.X.3
Ly, A.4
Glogowska, A.5
Czarny, J.6
Shevelev, A.7
Przewlocki, R.8
Henin, D.9
Trojan, J.10
-
27
-
-
0034936888
-
IGF-I triple helix strategy in hepatoma treatment
-
Upegui-Gonzalez LC, Ly A, Siercega M, Jarocki P, Trojan L, Duc HT, Pan Y, Shevelev A, Henin D, Anthony D, Nowak W, Popiela T, Trojan J. IGF-I triple helix strategy in hepatoma treatment. Hepatogastroenterology 2001; 48: 660-666
-
(2001)
Hepatogastroenterology
, vol.48
, pp. 660-666
-
-
Upegui-Gonzalez, L.C.1
Ly, A.2
Siercega, M.3
Jarocki, P.4
Trojan, L.5
Duc, H.T.6
Pan, Y.7
Shevelev, A.8
Henin, D.9
Anthony, D.10
Nowak, W.11
Popiela, T.12
Trojan, J.13
-
28
-
-
0036798045
-
Genetically engineered intracellular single-chain antibodies in gene-therapy
-
Bilbao G, Contreras JL, Curiel DT. Genetically engineered intracellular single-chain antibodies in gene-therapy. Mol Biotechnol 2002; 22: 191-211
-
(2002)
Mol Biotechnol
, vol.22
, pp. 191-211
-
-
Bilbao, G.1
Contreras, J.L.2
Curiel, D.T.3
-
29
-
-
0242523141
-
Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met
-
Nguyen TH, Loux N, Dagher I, Vons C, Carey K, Briand P, Hadchouel M, Franco D, Jouanneau J, Schwall R, Weber A. Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met. Cancer Gene Ther 2003; 10: 840-849
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 840-849
-
-
Nguyen, T.H.1
Loux, N.2
Dagher, I.3
Vons, C.4
Carey, K.5
Briand, P.6
Hadchouel, M.7
Franco, D.8
Jouanneau, J.9
Schwall, R.10
Weber, A.11
-
30
-
-
1142275457
-
Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells
-
Liu SX, Sun WS, Cao YL, Ma CH, Han LH, Zhang LN, Wang ZG, Zhu FL. Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells. World J Gastroenterol 2004; 10: 366-370
-
(2004)
World J Gastroenterol
, vol.10
, pp. 366-370
-
-
Liu, S.X.1
Sun, W.S.2
Cao, Y.L.3
Ma, C.H.4
Han, L.H.5
Zhang, L.N.6
Wang, Z.G.7
Zhu, F.L.8
-
31
-
-
8644265073
-
Antisense Tcf inhibits the neoplastic growth of liver cancer cells
-
Jiang Y, Zhou XD, Liu YK, Huang XW, Zhao Y, Xue Q, Sun RX, Chen J, Wu X. Antisense Tcf inhibits the neoplastic growth of liver cancer cells. J Cancer Res Clin Oncol 2004; 130: 671-678
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 671-678
-
-
Jiang, Y.1
Zhou, X.D.2
Liu, Y.K.3
Huang, X.W.4
Zhao, Y.5
Xue, Q.6
Sun, R.X.7
Chen, J.8
Wu, X.9
-
32
-
-
33645236561
-
In vitro RNA interference against beta-catenin inhibits the proliferation of pediatric hepatic tumors
-
Sangkhathat S, Kusafuka T, Miao J, Yoneda A, Nara K, Yamamoto S, Kaneda Y, Fukuzawa M. In vitro RNA interference against beta-catenin inhibits the proliferation of pediatric hepatic tumors. Int J Oncol 2006; 28: 715-722
-
(2006)
Int J Oncol
, vol.28
, pp. 715-722
-
-
Sangkhathat, S.1
Kusafuka, T.2
Miao, J.3
Yoneda, A.4
Nara, K.5
Yamamoto, S.6
Kaneda, Y.7
Fukuzawa, M.8
-
33
-
-
0028889597
-
Inhibition of fibroblast growth factor 2 expression by antisense RNA induced a loss of the transformed phenotype in a human hepatoma cell line
-
Maret A, Galy B, Arnaud E, Bayard F, Prats H. Inhibition of fibroblast growth factor 2 expression by antisense RNA induced a loss of the transformed phenotype in a human hepatoma cell line. Cancer Res 1995; 55: 5075-5079
-
(1995)
Cancer Res
, vol.55
, pp. 5075-5079
-
-
Maret, A.1
Galy, B.2
Arnaud, E.3
Bayard, F.4
Prats, H.5
-
34
-
-
1542374713
-
Inhibitory effect of antisense vascular endothelial growth factor 165 eukaryotic expression vector on proliferation of hepatocellular carcinoma cells
-
Gu S, Liu CJ, Qiao T, Sun XM, Chen LL, Zhang L. Inhibitory effect of antisense vascular endothelial growth factor 165 eukaryotic expression vector on proliferation of hepatocellular carcinoma cells. World J Gastroenterol 2004; 10: 535-539
-
(2004)
World J Gastroenterol
, vol.10
, pp. 535-539
-
-
Gu, S.1
Liu, C.J.2
Qiao, T.3
Sun, X.M.4
Chen, L.L.5
Zhang, L.6
-
35
-
-
30644459853
-
Effects of adenovirus-mediated human cyclooxygenase-2 antisense RNA on the growth of hepatocellular carcinoma
-
Wang XH, Li SB, Tong Q, Xie GJ, Wu QM. Effects of adenovirus-mediated human cyclooxygenase-2 antisense RNA on the growth of hepatocellular carcinoma. World J Gastroenterol 2005; 11: 6110-6114
-
(2005)
World J Gastroenterol
, vol.11
, pp. 6110-6114
-
-
Wang, X.H.1
Li, S.B.2
Tong, Q.3
Xie, G.J.4
Wu, Q.M.5
-
36
-
-
4444233040
-
Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells
-
Salvi A, Arici B, De Petro G, Barlati S. Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells. Mol Cancer Ther 2004; 3: 671-678
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 671-678
-
-
Salvi, A.1
Arici, B.2
De Petro, G.3
Barlati, S.4
-
37
-
-
20844457318
-
Expression of p28GANK and its correlation with RB in human hepatocellular carcinoma
-
Tan L, Fu XY, Liu SQ, Li HH, Hong Y, Wu MC, Wang HY. Expression of p28GANK and its correlation with RB in human hepatocellular carcinoma. Liver Int 2005; 25: 667-676
-
(2005)
Liver Int
, vol.25
, pp. 667-676
-
-
Tan, L.1
Fu, X.Y.2
Liu, S.Q.3
Li, H.H.4
Hong, Y.5
Wu, M.C.6
Wang, H.Y.7
-
38
-
-
20444498521
-
Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma
-
Li H, Fu X, Chen Y, Hong Y, Tan Y, Cao H, Wu M, Wang H. Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology 2005; 128: 2029-2041
-
(2005)
Gastroenterology
, vol.128
, pp. 2029-2041
-
-
Li, H.1
Fu, X.2
Chen, Y.3
Hong, Y.4
Tan, Y.5
Cao, H.6
Wu, M.7
Wang, H.8
-
39
-
-
1842633495
-
Use of suicide genes for cancer gene therapy: Study of the different approaches
-
Vassaux G, Martin-Duque P. Use of suicide genes for cancer gene therapy: study of the different approaches. Expert Opin Biol Ther 2004; 4: 519-530
-
(2004)
Expert Opin Biol Ther
, vol.4
, pp. 519-530
-
-
Vassaux, G.1
Martin-Duque, P.2
-
40
-
-
0034652614
-
Evaluation of HSV-tk gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes
-
Gerolami R, Cardoso J, Lewin M, Bralet MP, Sa Cunha A, Clement O, Brechot C, Tran PL. Evaluation of HSV-tk gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes. Cancer Res 2000; 60: 993-1001
-
(2000)
Cancer Res
, vol.60
, pp. 993-1001
-
-
Gerolami, R.1
Cardoso, J.2
Lewin, M.3
Bralet, M.P.4
Sa Cunha, A.5
Clement, O.6
Brechot, C.7
Tran, P.L.8
-
41
-
-
0036731059
-
Influence of the bystander effect on HSV-tk/GCV gene therapy. A review
-
van Dillen IJ, Minder NH, Vaalburg W, de Vries EF, Hospers GA. Influence of the bystander effect on HSV-tk/GCV gene therapy. A review. Curr Gene Ther 2002; 2: 307-322
-
(2002)
Curr Gene Ther
, vol.2
, pp. 307-322
-
-
van Dillen, I.J.1
Minder, N.H.2
Vaalburg, W.3
de Vries, E.F.4
Hospers, G.A.5
-
42
-
-
0037832252
-
Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: Fifteen years of application
-
Fillat C, Carrio M, Cascante A, Sangro B. Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application. Curr Gene Ther 2003; 3: 13-26
-
(2003)
Curr Gene Ther
, vol.3
, pp. 13-26
-
-
Fillat, C.1
Carrio, M.2
Cascante, A.3
Sangro, B.4
-
43
-
-
0030798508
-
Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma
-
Qian C, Idoate M, Bilbao R, Sangro B, Bruna O, Vazquez J, Prieto J. Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma. Hum Gene Ther 1997; 8: 349-358
-
(1997)
Hum Gene Ther
, vol.8
, pp. 349-358
-
-
Qian, C.1
Idoate, M.2
Bilbao, R.3
Sangro, B.4
Bruna, O.5
Vazquez, J.6
Prieto, J.7
-
44
-
-
0032549688
-
Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells
-
Yang L, Chiang Y, Lenz HJ, Danenberg KD, Spears CP, Gordon EM, Anderson WF, Parekh D. Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells. Hum Gene Ther 1998; 9: 719-728
-
(1998)
Hum Gene Ther
, vol.9
, pp. 719-728
-
-
Yang, L.1
Chiang, Y.2
Lenz, H.J.3
Danenberg, K.D.4
Spears, C.P.5
Gordon, E.M.6
Anderson, W.F.7
Parekh, D.8
-
45
-
-
0032896455
-
Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22
-
Dilber MS, Phelan A, Aints A, Mohamed AJ, Elliott G, Smith CI, O'Hare P. Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22. Gene Ther 1999; 6: 12-21
-
(1999)
Gene Ther
, vol.6
, pp. 12-21
-
-
Dilber, M.S.1
Phelan, A.2
Aints, A.3
Mohamed, A.J.4
Elliott, G.5
Smith, C.I.6
O'Hare, P.7
-
46
-
-
0030636585
-
Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors
-
Brand K, Arnold W, Bartels T, Lieber A, Kay MA, Strauss M, Dorken B. Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors. Cancer Gene Ther 1997; 4: 9-16
-
(1997)
Cancer Gene Ther
, vol.4
, pp. 9-16
-
-
Brand, K.1
Arnold, W.2
Bartels, T.3
Lieber, A.4
Kay, M.A.5
Strauss, M.6
Dorken, B.7
-
47
-
-
0037457060
-
Liver failure caused by herpes simplex virus thymidine kinase plus ganciclovir therapy is associated with mitochondrial dysfunction and mitochondrial DNA depletion
-
Herraiz M, Beraza N, Solano A, Sangro B, Montoya J, Qian C, Prieto J, Bustos M. Liver failure caused by herpes simplex virus thymidine kinase plus ganciclovir therapy is associated with mitochondrial dysfunction and mitochondrial DNA depletion. Hum Gene Ther 2003; 14: 463-472
-
(2003)
Hum Gene Ther
, vol.14
, pp. 463-472
-
-
Herraiz, M.1
Beraza, N.2
Solano, A.3
Sangro, B.4
Montoya, J.5
Qian, C.6
Prieto, J.7
Bustos, M.8
-
48
-
-
20444466384
-
Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients
-
Penuelas I, Mazzolini G, Boan JF, Sangro B, Marti-Climent J, Ruiz M, Ruiz J, Satyamurthy N, Qian C, Barrio JR, Phelps ME, Richter JA, Gambhir SS, Prieto J. Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. Gastroenterology 2005; 128: 1787-1795
-
(2005)
Gastroenterology
, vol.128
, pp. 1787-1795
-
-
Penuelas, I.1
Mazzolini, G.2
Boan, J.F.3
Sangro, B.4
Marti-Climent, J.5
Ruiz, M.6
Ruiz, J.7
Satyamurthy, N.8
Qian, C.9
Barrio, J.R.10
Phelps, M.E.11
Richter, J.A.12
Gambhir, S.S.13
Prieto, J.14
-
49
-
-
0037042181
-
Importance, mechanisms and limitations of the distant bystander effect in cancer gene therapy of experimental liver tumors
-
Engelmann C, Heslan JM, Fabre M, Lagarde JP, Klatzmann D, Panis Y. Importance, mechanisms and limitations of the distant bystander effect in cancer gene therapy of experimental liver tumors. Cancer Lett 2002; 179: 59-69
-
(2002)
Cancer Lett
, vol.179
, pp. 59-69
-
-
Engelmann, C.1
Heslan, J.M.2
Fabre, M.3
Lagarde, J.P.4
Klatzmann, D.5
Panis, Y.6
-
50
-
-
0035106088
-
Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
-
Agard C, Ligeza C, Dupas B, Izembart A, El Kouri C, Moullier P, Ferry N. Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther 2001; 8: 128-136
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 128-136
-
-
Agard, C.1
Ligeza, C.2
Dupas, B.3
Izembart, A.4
El Kouri, C.5
Moullier, P.6
Ferry, N.7
-
51
-
-
27944450394
-
Eradication of hepatocellular carcinoma xenografts by radiolabelled, lipiodol-inducible gene therapy
-
Kawashita Y, Ohtsuru A, Miki F, Kuroda H, Morishita M, Kaneda Y, Hatsushiba K, Kanematsu T, Yamashita S. Eradication of hepatocellular carcinoma xenografts by radiolabelled, lipiodol-inducible gene therapy. Gene Ther 2005; 12: 1633-1639
-
(2005)
Gene Ther
, vol.12
, pp. 1633-1639
-
-
Kawashita, Y.1
Ohtsuru, A.2
Miki, F.3
Kuroda, H.4
Morishita, M.5
Kaneda, Y.6
Hatsushiba, K.7
Kanematsu, T.8
Yamashita, S.9
-
52
-
-
0033119291
-
Superiority of yeast over bacterial cytosine deaminase for enzyme /prodrug gene therapy in colon cancer xenografts
-
Kievit E, Bershad E, Ng E, Sethna P, Dev I, Lawrence TS, Rehemtulla A. Superiority of yeast over bacterial cytosine deaminase for enzyme/ prodrug gene therapy in colon cancer xenografts. Cancer Res 1999; 59: 1417-1421
-
(1999)
Cancer Res
, vol.59
, pp. 1417-1421
-
-
Kievit, E.1
Bershad, E.2
Ng, E.3
Sethna, P.4
Dev, I.5
Lawrence, T.S.6
Rehemtulla, A.7
-
53
-
-
0036290399
-
The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model
-
Nyati MK, Symon Z, Kievit E, Dornfeld KJ, Rynkiewicz SD, Ross BD, Rehemtulla A, Lawrence TS. The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther 2002; 9: 844-849
-
(2002)
Gene Ther
, vol.9
, pp. 844-849
-
-
Nyati, M.K.1
Symon, Z.2
Kievit, E.3
Dornfeld, K.J.4
Rynkiewicz, S.D.5
Ross, B.D.6
Rehemtulla, A.7
Lawrence, T.S.8
-
54
-
-
0037308653
-
Regional delivery and selective expression of a high-activity yeast cytosine deaminase in an intrahepatic colon cancer model
-
Zhang M, Li S, Nyati MK, DeRemer S, Parsels J, Rehemtulla A, Ensminger WD, Lawrence TS. Regional delivery and selective expression of a high-activity yeast cytosine deaminase in an intrahepatic colon cancer model. Cancer Res 2003; 63: 658-663
-
(2003)
Cancer Res
, vol.63
, pp. 658-663
-
-
Zhang, M.1
Li, S.2
Nyati, M.K.3
DeRemer, S.4
Parsels, J.5
Rehemtulla, A.6
Ensminger, W.D.7
Lawrence, T.S.8
-
55
-
-
0036633912
-
Current progress in suicide gene therapy for cancer
-
Yazawa K, Fisher WE, Brunicardi FC. Current progress in suicide gene therapy for cancer. World J Surg 2002; 26: 783-789
-
(2002)
World J Surg
, vol.26
, pp. 783-789
-
-
Yazawa, K.1
Fisher, W.E.2
Brunicardi, F.C.3
-
56
-
-
0036909628
-
Cytochrome P450-based cancer gene therapy: Current status
-
Kan O, Kingsman S, Naylor S. Cytochrome P450-based cancer gene therapy: current status. Expert Opin Biol Ther 2002; 2: 857-868
-
(2002)
Expert Opin Biol Ther
, vol.2
, pp. 857-868
-
-
Kan, O.1
Kingsman, S.2
Naylor, S.3
-
57
-
-
2442696806
-
Virus-directed enzyme prodrug therapy: Intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer
-
Palmer DH, Mautner V, Mirza D, Oliff S, Gerritsen W, van der Sijp JR, Hubscher S, Reynolds G, Bonney S, Rajaratnam R, Hull D, Horne M, Ellis J, Mountain A, Hill S, Harris PA, Searle PF, Young LS, James ND, Kerr DJ. Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer. J Clin Oncol 2004; 22: 1546-1552
-
(2004)
J Clin Oncol
, vol.22
, pp. 1546-1552
-
-
Palmer, D.H.1
Mautner, V.2
Mirza, D.3
Oliff, S.4
Gerritsen, W.5
van der Sijp, J.R.6
Hubscher, S.7
Reynolds, G.8
Bonney, S.9
Rajaratnam, R.10
Hull, D.11
Horne, M.12
Ellis, J.13
Mountain, A.14
Hill, S.15
Harris, P.A.16
Searle, P.F.17
Young, L.S.18
James, N.D.19
Kerr, D.J.20
more..
-
58
-
-
6944247422
-
Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy
-
Kang JH, Chung JK, Lee YJ, Shin JH, Jeong JM, Lee DS, Lee MC. Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy. J Nucl Med 2004; 45: 1571-1576
-
(2004)
J Nucl Med
, vol.45
, pp. 1571-1576
-
-
Kang, J.H.1
Chung, J.K.2
Lee, Y.J.3
Shin, J.H.4
Jeong, J.M.5
Lee, D.S.6
Lee, M.C.7
-
59
-
-
7444221297
-
Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats
-
Faivre J, Clerc J, Gerolami R, Herve J, Longuet M, Liu B, Roux J, Moal F, Perricaudet M, Brechot C. Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats. Cancer Res 2004; 64: 8045-8051
-
(2004)
Cancer Res
, vol.64
, pp. 8045-8051
-
-
Faivre, J.1
Clerc, J.2
Gerolami, R.3
Herve, J.4
Longuet, M.5
Liu, B.6
Roux, J.7
Moal, F.8
Perricaudet, M.9
Brechot, C.10
-
60
-
-
0034575796
-
Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells
-
Abdul-Ghani R, Ohana P, Matouk I, Ayesh S, Ayesh B, Laster M, Bibi O, Giladi H, Molnar-Kimber K, Sughayer MA, de Groot N, Hochberg A. Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells. Mol Ther 2000; 2: 539-544
-
(2000)
Mol Ther
, vol.2
, pp. 539-544
-
-
Abdul-Ghani, R.1
Ohana, P.2
Matouk, I.3
Ayesh, S.4
Ayesh, B.5
Laster, M.6
Bibi, O.7
Giladi, H.8
Molnar-Kimber, K.9
Sughayer, M.A.10
de Groot, N.11
Hochberg, A.12
-
61
-
-
0034035078
-
Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha-fetoprotein gene
-
Kunitomi M, Takayama E, Suzuki S, Yasuda T, Tsutsui K, Nagaike K, Hiroi S, Tadakuma T. Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha-fetoprotein gene. Jpn J Cancer Res 2000; 91: 343-350
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 343-350
-
-
Kunitomi, M.1
Takayama, E.2
Suzuki, S.3
Yasuda, T.4
Tsutsui, K.5
Nagaike, K.6
Hiroi, S.7
Tadakuma, T.8
-
62
-
-
0035001741
-
The potential of TRAIL for cancer chemotherapy
-
Nagane M, Huang HJ, Cavenee WK. The potential of TRAIL for cancer chemotherapy. Apoptosis 2001; 6: 191-197
-
(2001)
Apoptosis
, vol.6
, pp. 191-197
-
-
Nagane, M.1
Huang, H.J.2
Cavenee, W.K.3
-
63
-
-
32944476780
-
Oral adeno-associated virus-sTRAIL gene therapy suppresses human hepatocellular carcinoma growth in mice
-
Ma H, Liu Y, Liu S, Xu R, Zheng D. Oral adeno-associated virus-sTRAIL gene therapy suppresses human hepatocellular carcinoma growth in mice. Hepatology 2005; 42: 1355-1363
-
(2005)
Hepatology
, vol.42
, pp. 1355-1363
-
-
Ma, H.1
Liu, Y.2
Liu, S.3
Xu, R.4
Zheng, D.5
-
64
-
-
19044397444
-
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells
-
Jacob D, Schumacher G, Bahra M, Davis J, Zhu HB, Zhang LD, Teraishi F, Neuhaus P, Fang BL. Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells. World J Gastroenterol 2005; 11: 2552-2556
-
(2005)
World J Gastroenterol
, vol.11
, pp. 2552-2556
-
-
Jacob, D.1
Schumacher, G.2
Bahra, M.3
Davis, J.4
Zhu, H.B.5
Zhang, L.D.6
Teraishi, F.7
Neuhaus, P.8
Fang, B.L.9
-
65
-
-
33644878512
-
Conditionally replicative adenovirus vector carrying TRAIL gene for enhanced oncolysis of human hepatocellular carcinoma
-
Ye X, Lu Q, Zhao Y, Ren Z, Ren XW, Qiu QH, Tong Y, Liang M, Hu F, Chen HZ. Conditionally replicative adenovirus vector carrying TRAIL gene for enhanced oncolysis of human hepatocellular carcinoma. Int J Mol Med 2005; 16: 1179-1184
-
(2005)
Int J Mol Med
, vol.16
, pp. 1179-1184
-
-
Ye, X.1
Lu, Q.2
Zhao, Y.3
Ren, Z.4
Ren, X.W.5
Qiu, Q.H.6
Tong, Y.7
Liang, M.8
Hu, F.9
Chen, H.Z.10
-
66
-
-
33644647055
-
Adenovirus E1A reverses the resistance of normal primary human lung fibroblast cells to TRAIL through DR5 upregulation and caspase 8-dependent pathway
-
Zhu H, Ling W, Hu B, Su Y, Qiu S, Xiao W, Qi Y. Adenovirus E1A reverses the resistance of normal primary human lung fibroblast cells to TRAIL through DR5 upregulation and caspase 8-dependent pathway. Cancer Biol Ther 2006; 5: 180-188
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 180-188
-
-
Zhu, H.1
Ling, W.2
Hu, B.3
Su, Y.4
Qiu, S.5
Xiao, W.6
Qi, Y.7
-
67
-
-
23244451649
-
In vivo hydrodynamic delivery of cDNA encoding IL-2: Rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells
-
Ortaldo JR, Winkler-Pickett RT, Bere EW Jr, Watanabe M, Murphy WJ, Wiltrout RH. In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells. J Immunol 2005; 175: 693-699
-
(2005)
J Immunol
, vol.175
, pp. 693-699
-
-
Ortaldo, J.R.1
Winkler-Pickett, R.T.2
Bere Jr., E.W.3
Watanabe, M.4
Murphy, W.J.5
Wiltrout, R.H.6
-
68
-
-
84941944867
-
Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication
-
Miller PW, Sharma S, Stolina M, Butterfield LH, Luo J, Lin Y, Dohadwala M, Batra RK, Wu L, Economou JS, Dubinett SM. Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication. Hum Gene Ther 2000; 11: 53-65
-
(2000)
Hum Gene Ther
, vol.11
, pp. 53-65
-
-
Miller, P.W.1
Sharma, S.2
Stolina, M.3
Butterfield, L.H.4
Luo, J.5
Lin, Y.6
Dohadwala, M.7
Batra, R.K.8
Wu, L.9
Economou, J.S.10
Dubinett, S.M.11
-
69
-
-
0033218662
-
Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12
-
Mazzolini G, Qian C, Xie X, Sun Y, Lasarte JJ, Drozdzik M, Prieto J. Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12. Cancer Gene Ther 1999; 6: 514-522
-
(1999)
Cancer Gene Ther
, vol.6
, pp. 514-522
-
-
Mazzolini, G.1
Qian, C.2
Xie, X.3
Sun, Y.4
Lasarte, J.J.5
Drozdzik, M.6
Prieto, J.7
-
70
-
-
27744433869
-
Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells
-
Vera M, Razquin N, Prieto J, Melero I, Fortes P, Gonzalez-Aseguinolaza G. Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells. Mol Ther 2005; 12: 950-999
-
(2005)
Mol Ther
, vol.12
, pp. 950-999
-
-
Vera, M.1
Razquin, N.2
Prieto, J.3
Melero, I.4
Fortes, P.5
Gonzalez-Aseguinolaza, G.6
-
71
-
-
0345328613
-
Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma
-
Leng J, Zhang L, Yao H, Cao X. Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma. Chin Med J (Engl) 2003; 116: 1475-1479
-
(2003)
Chin Med J (Engl)
, vol.116
, pp. 1475-1479
-
-
Leng, J.1
Zhang, L.2
Yao, H.3
Cao, X.4
-
72
-
-
10744230081
-
Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma
-
Kishida T, Asada H, Itokawa Y, Cui FD, Shin-Ya M, Gojo S, Yasutomi K, Ueda Y, Yamagishi H, Imanishi J, Mazda O. Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma. Mol Ther 2003; 8: 552-558
-
(2003)
Mol Ther
, vol.8
, pp. 552-558
-
-
Kishida, T.1
Asada, H.2
Itokawa, Y.3
Cui, F.D.4
Shin-Ya, M.5
Gojo, S.6
Yasutomi, K.7
Ueda, Y.8
Yamagishi, H.9
Imanishi, J.10
Mazda, O.11
-
73
-
-
12444328351
-
Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects
-
Ugai S, Shimozato O, Yu L, Wang YQ, Kawamura K, Yamamoto H, Yamagchi T, Saisho H, Sakiyama S, Tagawa M. Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects. Cancer Gene Ther 2003; 10: 771-778
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 771-778
-
-
Ugai, S.1
Shimozato, O.2
Yu, L.3
Wang, Y.Q.4
Kawamura, K.5
Yamamoto, H.6
Yamaguchi, T.7
Saisho, H.8
Sakiyama, S.9
Tagawa, M.10
-
74
-
-
33644523055
-
Molecular target-based therapy of pancreatic cancer
-
Lebedeva IV, Sarkar D, Su ZZ, Gopalkrishnan RV, Athar M, Randolph A, Valerie K, Dent P, Fisher PB. Molecular target-based therapy of pancreatic cancer. Cancer Res 2006; 66: 2403-2413
-
(2006)
Cancer Res
, vol.66
, pp. 2403-2413
-
-
Lebedeva, I.V.1
Sarkar, D.2
Su, Z.Z.3
Gopalkrishnan, R.V.4
Athar, M.5
Randolph, A.6
Valerie, K.7
Dent, P.8
Fisher, P.B.9
-
75
-
-
0035125085
-
Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells
-
Santodonato L, Ferrantini M, Palombo F, Aurisicchio L, Delmastro P, La Monica N, Di Marco S, Ciliberto G, Du MX, Taylor MW, Belardelli F. Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells. Cancer Gene Ther 2001; 8: 63-72
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 63-72
-
-
Santodonato, L.1
Ferrantini, M.2
Palombo, F.3
Aurisicchio, L.4
Delmastro, P.5
La Monica, N.6
Di Marco, S.7
Ciliberto, G.8
Du, M.X.9
Taylor, M.W.10
Belardelli, F.11
-
76
-
-
29144520504
-
Antitumor efficacy of AAV-mediated systemic delivery of interferon-beta
-
Streck CJ, Dickson PV, Ng CY, Zhou J, Hall MM, Gray JT, Nathwani AC, Davidoff AM. Antitumor efficacy of AAV-mediated systemic delivery of interferon-beta. Cancer Gene Ther 2006; 13: 99-106
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 99-106
-
-
Streck, C.J.1
Dickson, P.V.2
Ng, C.Y.3
Zhou, J.4
Hall, M.M.5
Gray, J.T.6
Nathwani, A.C.7
Davidoff, A.M.8
-
77
-
-
0035048604
-
Regression of primary hepatocarcinoma in cancer-prone transgenic mice by local interferon-gamma delivery is associated with macrophages recruitment and nitric oxide production
-
Baratin M, Ziol M, Romieu R, Kayibanda M, Gouilleux F, Briand P, Leroy P, Haddada H, Renia L, Viguier M, Guillet JG. Regression of primary hepatocarcinoma in cancer-prone transgenic mice by local interferon-gamma delivery is associated with macrophages recruitment and nitric oxide production. Cancer Gene Ther 2001; 8: 193-202
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 193-202
-
-
Baratin, M.1
Ziol, M.2
Romieu, R.3
Kayibanda, M.4
Gouilleux, F.5
Briand, P.6
Leroy, P.7
Haddada, H.8
Renia, L.9
Viguier, M.10
Guillet, J.G.11
-
78
-
-
0031052118
-
Complete regression of established murine hepatocellular carcinoma by in vivo tumor necrosis factor alpha gene transfer
-
Cao G, Kuriyama S, Du P, Sakamoto T, Kong X, Masui K, Qi Z. Complete regression of established murine hepatocellular carcinoma by in vivo tumor necrosis factor alpha gene transfer. Gastroenterology 1997; 112: 501-510
-
(1997)
Gastroenterology
, vol.112
, pp. 501-510
-
-
Cao, G.1
Kuriyama, S.2
Du, P.3
Sakamoto, T.4
Kong, X.5
Masui, K.6
Qi, Z.7
-
79
-
-
1542571428
-
Concurrent delivery of GM-CSF and endostatin genes by a single adenoviral vector provides a synergistic effect on the treatment of orthotopic liver tumors
-
Tai KF, Chen PJ, Chen DS, Hwang LH. Concurrent delivery of GM-CSF and endostatin genes by a single adenoviral vector provides a synergistic effect on the treatment of orthotopic liver tumors. J Gene Med 2003; 5: 386-398
-
(2003)
J Gene Med
, vol.5
, pp. 386-398
-
-
Tai, K.F.1
Chen, P.J.2
Chen, D.S.3
Hwang, L.H.4
-
80
-
-
0345358584
-
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
-
Trinchieri G, Pflanz S, Kastelein RA. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 2003; 19: 641-644
-
(2003)
Immunity
, vol.19
, pp. 641-644
-
-
Trinchieri, G.1
Pflanz, S.2
Kastelein, R.A.3
-
81
-
-
0029922177
-
Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
-
Sgadari C, Angiolillo AL, Tosato G. Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 1996; 87: 3877-3882
-
(1996)
Blood
, vol.87
, pp. 3877-3882
-
-
Sgadari, C.1
Angiolillo, A.L.2
Tosato, G.3
-
82
-
-
0033692861
-
Adenovirus-interleukin-12-mediated tumor regression in a murine hepatocellular carcinoma model is not dependent on CD1-restricted natural killer T cells
-
Andrews KJ, Ribas A, Butterfield LH, Vollmer CM, Eilber FC, Dissette VB, Nelson SD, Shintaku P, Mekhoubad S, Nakayama T, Taniguchi M, Glaspy JA, McBride WH, Economou JS. Adenovirus-interleukin-12-mediated tumor regression in a murine hepatocellular carcinoma model is not dependent on CD1-restricted natural killer T cells. Cancer Res 2000; 60: 6457-6464
-
(2000)
Cancer Res
, vol.60
, pp. 6457-6464
-
-
Andrews, K.J.1
Ribas, A.2
Butterfield, L.H.3
Vollmer, C.M.4
Eilber, F.C.5
Dissette, V.B.6
Nelson, S.D.7
Shintaku, P.8
Mekhoubad, S.9
Nakayama, T.10
Taniguchi, M.11
Glaspy, J.A.12
McBride, W.H.13
Economou, J.S.14
-
83
-
-
0030887047
-
Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
-
Atkins MB, Robertson MJ, Gordon M, Lotze MT, DeCoste M, DuBois JS, Ritz J, Sandler AB, Edington HD, Garzone PD, Mier JW, Canning CM, Battiato L, Tahara H, Sherman ML. Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res 1997; 3: 409-417
-
(1997)
Clin Cancer Res
, vol.3
, pp. 409-417
-
-
Atkins, M.B.1
Robertson, M.J.2
Gordon, M.3
Lotze, M.T.4
DeCoste, M.5
DuBois, J.S.6
Ritz, J.7
Sandler, A.B.8
Edington, H.D.9
Garzone, P.D.10
Mier, J.W.11
Canning, C.M.12
Battiato, L.13
Tahara, H.14
Sherman, M.L.15
-
84
-
-
0030766971
-
Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production
-
Leonard JP, Sherman ML, Fisher GL, Buchanan LJ, Larsen G, Atkins MB, Sosman JA, Dutcher JP, Vogelzang NJ, Ryan JL. Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood 1997; 90: 2541-2548
-
(1997)
Blood
, vol.90
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
Buchanan, L.J.4
Larsen, G.5
Atkins, M.B.6
Sosman, J.A.7
Dutcher, J.P.8
Vogelzang, N.J.9
Ryan, J.L.10
-
86
-
-
0035197719
-
Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12
-
Barajas M, Mazzolini G, Genove G, Bilbao R, Narvaiza I, Schmitz V, Sangro B, Melero I, Qian C, Prieto J. Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12. Hepatology 2001; 33: 52-61
-
(2001)
Hepatology
, vol.33
, pp. 52-61
-
-
Barajas, M.1
Mazzolini, G.2
Genove, G.3
Bilbao, R.4
Narvaiza, I.5
Schmitz, V.6
Sangro, B.7
Melero, I.8
Qian, C.9
Prieto, J.10
-
87
-
-
16344387497
-
Low-dose adenoviral immunotherapy of rat hepatocellular carcinoma using single-chain interleukin-12
-
Waehler R, Ittrich H, Mueller L, Krupski G, Ameis D, Schnieders F. Low-dose adenoviral immunotherapy of rat hepatocellular carcinoma using single-chain interleukin-12. Hum Gene Ther 2005; 16: 307-317
-
(2005)
Hum Gene Ther
, vol.16
, pp. 307-317
-
-
Waehler, R.1
Ittrich, H.2
Mueller, L.3
Krupski, G.4
Ameis, D.5
Schnieders, F.6
-
88
-
-
2342570309
-
Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors
-
Sangro B, Mazzolini G, Ruiz J, Herraiz M, Quiroga J, Herrero I, Benito A, Larrache J, Pueyo J, Subtil JC, Olague C, Sola J, Sadaba B, Lacasa C, Melero I, Qian C, Prieto J. Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors. J Clin Oncol 2004; 22: 1389-1397
-
(2004)
J Clin Oncol
, vol.22
, pp. 1389-1397
-
-
Sangro, B.1
Mazzolini, G.2
Ruiz, J.3
Herraiz, M.4
Quiroga, J.5
Herrero, I.6
Benito, A.7
Larrache, J.8
Pueyo, J.9
Subtil, J.C.10
Olague, C.11
Sola, J.12
Sadaba, B.13
Lacasa, C.14
Melero, I.15
Qian, C.16
Prieto, J.17
-
89
-
-
0347991866
-
Prolonged and inducible transgene expression in the liver using gutless adenovirus: A potential therapy for liver cancer
-
Wang L, Hernandez-Alcoceba R, Shankar V, Zabala M, Kochanek S, Sangro B, Kramer MG, Prieto J, Qian C. Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer. Gastroenterology 2004; 126: 278-289
-
(2004)
Gastroenterology
, vol.126
, pp. 278-289
-
-
Wang, L.1
Hernandez-Alcoceba, R.2
Shankar, V.3
Zabala, M.4
Kochanek, S.5
Sangro, B.6
Kramer, M.G.7
Prieto, J.8
Qian, C.9
-
90
-
-
0031012127
-
Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo
-
Lieschke GJ, Rao PK, Gately MK, Mulligan RC. Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo. Nat Biotechnol 1997; 15: 35-40
-
(1997)
Nat Biotechnol
, vol.15
, pp. 35-40
-
-
Lieschke, G.J.1
Rao, P.K.2
Gately, M.K.3
Mulligan, R.C.4
-
91
-
-
26944435963
-
IL-24 inhibits the growth of hepatoma cells in vivo
-
Chen WY, Cheng YT, Lei HY, Cheng CP, Wang CW, Chang MS. IL-24 inhibits the growth of hepatoma cells in vivo. Genes Immun 2005; 6: 493-499
-
(2005)
Genes Immun
, vol.6
, pp. 493-499
-
-
Chen, W.Y.1
Cheng, Y.T.2
Lei, H.Y.3
Cheng, C.P.4
Wang, C.W.5
Chang, M.S.6
-
92
-
-
25144471132
-
TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha, for patients with advanced solid tumors: Surgical experience and long-term follow-up
-
McLoughlin JM, McCarty TM, Cunningham C, Clark V, Senzer N, Nemunaitis J, Kuhn JA. TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha, for patients with advanced solid tumors: surgical experience and long-term follow-up. Ann Surg Oncol 2005; 12: 825-830
-
(2005)
Ann Surg Oncol
, vol.12
, pp. 825-830
-
-
McLoughlin, J.M.1
McCarty, T.M.2
Cunningham, C.3
Clark, V.4
Senzer, N.5
Nemunaitis, J.6
Kuhn, J.A.7
-
93
-
-
33745593993
-
mda-7/IL-24: Multifunctional cancer-specific apoptosis-inducing cytokine
-
Gupta P, Su ZZ, Lebedeva IV, Sarkar D, Sauane M, Emdad L, Bachelor MA, Grant S, Curiel DT, Dent P, Fisher PB. mda-7/IL-24: Multifunctional cancer-specific apoptosis-inducing cytokine. Pharmacol Ther 2006; 111: 596-628
-
(2006)
Pharmacol Ther
, vol.111
, pp. 596-628
-
-
Gupta, P.1
Su, Z.Z.2
Lebedeva, I.V.3
Sarkar, D.4
Sauane, M.5
Emdad, L.6
Bachelor, M.A.7
Grant, S.8
Curiel, D.T.9
Dent, P.10
Fisher, P.B.11
-
94
-
-
27844459421
-
Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
-
Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells. Oncogene 2005; 24: 7552-7566
-
(2005)
Oncogene
, vol.24
, pp. 7552-7566
-
-
Su, Z.1
Emdad, L.2
Sauane, M.3
Lebedeva, I.V.4
Sarkar, D.5
Gupta, P.6
James, C.D.7
Randolph, A.8
Valerie, K.9
Walter, M.R.10
Dent, P.11
Fisher, P.B.12
-
95
-
-
0034616629
-
Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: Long- term remission of liver metastases in a mouse model
-
Martinet O, Ermekova V, Qiao JQ, Sauter B, Mandeli J, Chen L, Chen SH. Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: long- term remission of liver metastases in a mouse model. J Natl Cancer Inst 2000; 92: 931-936
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 931-936
-
-
Martinet, O.1
Ermekova, V.2
Qiao, J.Q.3
Sauter, B.4
Mandeli, J.5
Chen, L.6
Chen, S.H.7
-
96
-
-
0035925568
-
Large nontransplanted hepatocellular carcinoma in woodchucks: Treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes
-
Putzer BM, Stiewe T, Rodicker F, Schildgen O, Ruhm S, Dirsch O, Fiedler M, Damen U, Tennant B, Scherer C, Graham FL, Roggendorf M. Large nontransplanted hepatocellular carcinoma in woodchucks: treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes. J Natl Cancer Inst 2001; 93: 472-479
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 472-479
-
-
Putzer, B.M.1
Stiewe, T.2
Rodicker, F.3
Schildgen, O.4
Ruhm, S.5
Dirsch, O.6
Fiedler, M.7
Damen, U.8
Tennant, B.9
Scherer, C.10
Graham, F.L.11
Roggendorf, M.12
-
97
-
-
0034962640
-
Adenovirus-mediated CD40 ligand gene therapy in a rat model of orthotopic hepatocellular carcinoma
-
Schmitz V, Barajas M, Wang L, Peng D, Duarte M, Prieto J, Qian C. Adenovirus-mediated CD40 ligand gene therapy in a rat model of orthotopic hepatocellular carcinoma. Hepatology 2001; 34: 72-81
-
(2001)
Hepatology
, vol.34
, pp. 72-81
-
-
Schmitz, V.1
Barajas, M.2
Wang, L.3
Peng, D.4
Duarte, M.5
Prieto, J.6
Qian, C.7
-
98
-
-
0034653833
-
Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked anti-tumoral synergy
-
Narvaiza I, Mazzolini G, Barajas M, Duarte M, Zaratiegui M, Qian C, Melero I, Prieto J. Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked anti-tumoral synergy. J Immunol 2000; 164: 3112-3122
-
(2000)
J Immunol
, vol.164
, pp. 3112-3122
-
-
Narvaiza, I.1
Mazzolini, G.2
Barajas, M.3
Duarte, M.4
Zaratiegui, M.5
Qian, C.6
Melero, I.7
Prieto, J.8
-
99
-
-
0036316062
-
IFN-gamma-independent synergistic effects of IL-12 and IL-15 induce anti-tumor immune responses in syngeneic mice
-
Comes A, Di Carlo E, Musiani P, Rosso O, Meazza R, Chiodoni C, Colombo MP, Ferrini S. IFN-gamma-independent synergistic effects of IL-12 and IL-15 induce anti-tumor immune responses in syngeneic mice. Eur J Immunol 2002; 32: 1914-1923
-
(2002)
Eur J Immunol
, vol.32
, pp. 1914-1923
-
-
Comes, A.1
Di Carlo, E.2
Musiani, P.3
Rosso, O.4
Meazza, R.5
Chiodoni, C.6
Colombo, M.P.7
Ferrini, S.8
-
100
-
-
0034779612
-
Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma
-
Wang Z, Qiu SJ, Ye SL, Tang ZY, Xiao X. Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma. Cancer Gene Ther 2001; 8: 751-758
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 751-758
-
-
Wang, Z.1
Qiu, S.J.2
Ye, S.L.3
Tang, Z.Y.4
Xiao, X.5
-
101
-
-
0037925143
-
Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis
-
Mazzolini G, Narvaiza I, Martinez-Cruz LA, Arina A, Barajas M, Galofre JC, Qian C, Mato JM, Prieto J, Melero I. Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis. Gene Ther 2003;10:1067-1078
-
(2003)
Gene Ther
, vol.10
, pp. 1067-1078
-
-
Mazzolini, G.1
Narvaiza, I.2
Martinez-Cruz, L.A.3
Arina, A.4
Barajas, M.5
Galofre, J.C.6
Qian, C.7
Mato, J.M.8
Prieto, J.9
Melero, I.10
-
102
-
-
4344623222
-
Transfection of IL-2 and/or IL-12 genes into spleen in treatment of rat liver cancer
-
You TG, Wang HS, Yang JH, Qian QJ, Fan RF, Wu MC. Transfection of IL-2 and/or 1L-12 genes into spleen in treatment of rat liver cancer. World J Gastroenterol 2004; 10: 2190-2194
-
(2004)
World J Gastroenterol
, vol.10
, pp. 2190-2194
-
-
You, T.G.1
Wang, H.S.2
Yang, J.H.3
Qian, Q.J.4
Fan, R.F.5
Wu, M.C.6
-
103
-
-
10444241232
-
Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases
-
Alves A, Vibert E, Trajcevski S, Solly S, Fabre M, Soubrane O, Qian C, Prieto J, Klatzmann D, Panis Y. Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases. Cancer Gene Ther 2004; 11: 782-789
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 782-789
-
-
Alves, A.1
Vibert, E.2
Trajcevski, S.3
Solly, S.4
Fabre, M.5
Soubrane, O.6
Qian, C.7
Prieto, J.8
Klatzmann, D.9
Panis, Y.10
-
104
-
-
17044398835
-
Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma
-
Stefani AL, Barzon L, Castagliuolo I, Guido M, Pacenti M, Parolin C, Farinati F, Palu G. Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma. J Hepatol 2005; 42: 728-735
-
(2005)
J Hepatol
, vol.42
, pp. 728-735
-
-
Stefani, A.L.1
Barzon, L.2
Castagliuolo, I.3
Guido, M.4
Pacenti, M.5
Parolin, C.6
Farinati, F.7
Palu, G.8
-
105
-
-
0033769892
-
Mouse alpha-fetoprotein-specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice
-
Grimm CF, Ortmann D, Mohr L, Michalak S, Krohne TU, Meckel S, Eisele S, Encke J, Blum HE, Geissler M. Mouse alpha-fetoprotein-specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice. Gastroenterology 2000; 119: 1104-1112
-
(2000)
Gastroenterology
, vol.119
, pp. 1104-1112
-
-
Grimm, C.F.1
Ortmann, D.2
Mohr, L.3
Michalak, S.4
Krohne, T.U.5
Meckel, S.6
Eisele, S.7
Encke, J.8
Blum, H.E.9
Geissler, M.10
-
106
-
-
1542648421
-
Diverse efficacy of vaccination therapy using the alpha-fetoprotein gene against mouse hepatocellular carcinoma
-
Saeki A, Nakao K, Nagayama Y, Yanagi K, Matsumoto K, Hayashi T, Ishikawa H, Hamasaki K, Ishii N, Eguchi K. Diverse efficacy of vaccination therapy using the alpha-fetoprotein gene against mouse hepatocellular carcinoma. Int J Mol Med 2004; 13: 111-116
-
(2004)
Int J Mol Med
, vol.13
, pp. 111-116
-
-
Saeki, A.1
Nakao, K.2
Nagayama, Y.3
Yanagi, K.4
Matsumoto, K.5
Hayashi, T.6
Ishikawa, H.7
Hamasaki, K.8
Ishii, N.9
Eguchi, K.10
-
107
-
-
2342635773
-
Treatment of murine hepatocellular carcinoma using genetically modified cells to express interleukin-12
-
Peron JM, Couderc B, Rochaix P, Douin-Echinard V, Asnacios A, Souque A, Voigt JJ, Buscail L, Vinel JP, Favre G. Treatment of murine hepatocellular carcinoma using genetically modified cells to express interleukin-12. J Gastroenterol Hepatol 2004; 19: 388-396
-
(2004)
J Gastroenterol Hepatol
, vol.19
, pp. 388-396
-
-
Peron, J.M.1
Couderc, B.2
Rochaix, P.3
Douin-Echinard, V.4
Asnacios, A.5
Souque, A.6
Voigt, J.J.7
Buscail, L.8
Vinel, J.P.9
Favre, G.10
-
108
-
-
0142245326
-
Prevention of hepatocellular carcinoma in mice by IL-2 and B7-1 genes co-transfected liver cancer cell vaccines
-
Ge NL, Ye SL, Zheng N, Sun RX, Liu YK, Tang ZY. Prevention of hepatocellular carcinoma in mice by IL-2 and B7-1 genes co-transfected liver cancer cell vaccines. World J Gastroenterol 2003; 9: 2182-2185
-
(2003)
World J Gastroenterol
, vol.9
, pp. 2182-2185
-
-
Ge, N.L.1
Ye, S.L.2
Zheng, N.3
Sun, R.X.4
Liu, Y.K.5
Tang, Z.Y.6
-
109
-
-
0345104277
-
Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma
-
Vollmer CM Jr, Eilber FC, Butterfield LH, Ribas A, Dissette VB, Koh A, Montejo LD, Lee MC, Andrews KJ, McBride WH, Glaspy JA, Economou JS. Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma. Cancer Res 1999; 59: 3064-3067
-
(1999)
Cancer Res
, vol.59
, pp. 3064-3067
-
-
Vollmer Jr., C.M.1
Eilber, F.C.2
Butterfield, L.H.3
Ribas, A.4
Dissette, V.B.5
Koh, A.6
Montejo, L.D.7
Lee, M.C.8
Andrews, K.J.9
McBride, W.H.10
Glaspy, J.A.11
Economou, J.S.12
-
110
-
-
0032844949
-
Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas
-
Melero I, Duarte M, Ruiz J, Sangro B, Galofre J, Mazzolini G, Bustos M, Qian C, Prieto J. Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas. Gene Ther 1999; 6: 1779-1784
-
(1999)
Gene Ther
, vol.6
, pp. 1779-1784
-
-
Melero, I.1
Duarte, M.2
Ruiz, J.3
Sangro, B.4
Galofre, J.5
Mazzolini, G.6
Bustos, M.7
Qian, C.8
Prieto, J.9
-
111
-
-
0035328585
-
Enhanced activation of human T cells via avipox vector-mediated hyperexpression of a triad of costimulatory molecules in human dendritic cells
-
Zhu M, Terasawa H, Gulley J, Panicali D, Arlen P, Schlom J, Tsang KY. Enhanced activation of human T cells via avipox vector-mediated hyperexpression of a triad of costimulatory molecules in human dendritic cells. Cancer Res 2001; 61: 3725-3734
-
(2001)
Cancer Res
, vol.61
, pp. 3725-3734
-
-
Zhu, M.1
Terasawa, H.2
Gulley, J.3
Panicali, D.4
Arlen, P.5
Schlom, J.6
Tsang, K.Y.7
-
112
-
-
0036463811
-
Cytokine gene transfer into dendritic cells for cancer treatment
-
Tirapu I, Rodriguez-Calvillo M, Qian C, Duarte M, Smerdou C, Palencia B, Mazzolini G, Prieto J, Melero I. Cytokine gene transfer into dendritic cells for cancer treatment. Curr Gene Ther 2002; 2: 79-89
-
(2002)
Curr Gene Ther
, vol.2
, pp. 79-89
-
-
Tirapu, I.1
Rodriguez-Calvillo, M.2
Qian, C.3
Duarte, M.4
Smerdou, C.5
Palencia, B.6
Mazzolini, G.7
Prieto, J.8
Melero, I.9
-
113
-
-
20044396550
-
Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
-
Mazzolini G, Alfaro C, Sangro B, Feijoo E, Ruiz J, Benito A, Tirapu I, Arina A, Sola J, Herraiz M, Lucena F, Olague C, Subtil J, Quiroga J, Herrero I, Sadaba B, Bendandi M, Qian C, Prieto J, Melero I. Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas. J Clin Oncol 2005; 23: 999-1010
-
(2005)
J Clin Oncol
, vol.23
, pp. 999-1010
-
-
Mazzolini, G.1
Alfaro, C.2
Sangro, B.3
Feijoo, E.4
Ruiz, J.5
Benito, A.6
Tirapu, I.7
Arina, A.8
Sola, J.9
Herraiz, M.10
Lucena, F.11
Olague, C.12
Subtil, J.13
Quiroga, J.14
Herrero, I.15
Sadaba, B.16
Bendandi, M.17
Qian, C.18
Prieto, J.19
Melero, I.20
more..
-
114
-
-
22044438503
-
Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8
-
Feijoo E, Alfaro C, Mazzolini G, Serra P, Penuelas I, Arina A, Huarte E, Tirapu I, Palencia B, Murillo O, Ruiz J, Sangro B, Richter JA, Prieto J, Melero I. Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8. Int J Cancer 2005; 116: 275-281
-
(2005)
Int J Cancer
, vol.116
, pp. 275-281
-
-
Feijoo, E.1
Alfaro, C.2
Mazzolini, G.3
Serra, P.4
Penuelas, I.5
Arina, A.6
Huarte, E.7
Tirapu, I.8
Palencia, B.9
Murillo, O.10
Ruiz, J.11
Sangro, B.12
Richter, J.A.13
Prieto, J.14
Melero, I.15
-
115
-
-
0033971393
-
Adenoviral gene transfer of interleukin 12 into tumors synergizes with adoptive T cell therapy both at the induction and effector level
-
Mazzolini G, Qian C, Narvaiza I, Barajas M, Borras-Cuesta F, Xie X, Duarte M, Melero I, Prieto J. Adenoviral gene transfer of interleukin 12 into tumors synergizes with adoptive T cell therapy both at the induction and effector level. Hum Gene Ther 2000; 11: 113-125
-
(2000)
Hum Gene Ther
, vol.11
, pp. 113-125
-
-
Mazzolini, G.1
Qian, C.2
Narvaiza, I.3
Barajas, M.4
Borras-Cuesta, F.5
Xie, X.6
Duarte, M.7
Melero, I.8
Prieto, J.9
-
116
-
-
23344452388
-
Blockade of B7-H1 with sPD-1 improves immunity against murine hepatocarcinoma
-
He L, Zhang G, He Y, Zhu H, Zhang H, Feng Z. Blockade of B7-H1 with sPD-1 improves immunity against murine hepatocarcinoma. Anticancer Res 2005; 25: 3309-3313
-
(2005)
Anticancer Res
, vol.25
, pp. 3309-3313
-
-
He, L.1
Zhang, G.2
He, Y.3
Zhu, H.4
Zhang, H.5
Feng, Z.6
-
117
-
-
33344472286
-
Antiangiogenesis in cancer therapy - Endostatin and its mechanisms of action
-
Folkman J. Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action. Exp Cell Res 2006; 312: 594-607
-
(2006)
Exp Cell Res
, vol.312
, pp. 594-607
-
-
Folkman, J.1
-
118
-
-
32444450942
-
A comparison of antiangiogenic therapies for the prevention of liver metastases
-
Mi J, Sarraf-Yazdi S, Zhang X, Cao Y, Dewhirst MW, Kontos CD, Li CY, Clary BM. A comparison of antiangiogenic therapies for the prevention of liver metastases. J Surg Res 2006; 131: 97-104
-
(2006)
J Surg Res
, vol.131
, pp. 97-104
-
-
Mi, J.1
Sarraf-Yazdi, S.2
Zhang, X.3
Cao, Y.4
Dewhirst, M.W.5
Kontos, C.D.6
Li, C.Y.7
Clary, B.M.8
-
119
-
-
21044453333
-
Inhibitory effect of adeno-associated virus-mediated gene transfer of human endostatin on hepatocellular carcinoma
-
Liu H, Peng CH, Liu YB, Wu YL, Zhao ZM, Wang Y, Han BS. Inhibitory effect of adeno-associated virus-mediated gene transfer of human endostatin on hepatocellular carcinoma. World J Gastroenterol 2005; 11: 3331-3334
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3331-3334
-
-
Liu, H.1
Peng, C.H.2
Liu, Y.B.3
Wu, Y.L.4
Zhao, Z.M.5
Wang, Y.6
Han, B.S.7
-
120
-
-
11344267601
-
Inhibition of tumor growth in xenografted nude mice with adenovirus-mediated endostatin gene comparison with recombinant endostatin protein
-
Liang ZH, Wu PH, Li L, Xue G, Zeng YX, Huang WL. Inhibition of tumor growth in xenografted nude mice with adenovirus-mediated endostatin gene comparison with recombinant endostatin protein. Chin Med J (Engl) 2004; 117: 1809-1814
-
(2004)
Chin Med J (Engl)
, vol.117
, pp. 1809-1814
-
-
Liang, Z.H.1
Wu, P.H.2
Li, L.3
Xue, G.4
Zeng, Y.X.5
Huang, W.L.6
-
121
-
-
2342426204
-
Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse model
-
Hong SY, Lee MH, Kim KS, Jung HC, Roh JK, Hyung WJ, Noh SH, Choi SH. Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse model. World J Gastroenterol 2004; 10: 1191-1197
-
(2004)
World J Gastroenterol
, vol.10
, pp. 1191-1197
-
-
Hong, S.Y.1
Lee, M.H.2
Kim, K.S.3
Jung, H.C.4
Roh, J.K.5
Hyung, W.J.6
Noh, S.H.7
Choi, S.H.8
-
122
-
-
13444257501
-
Bifidobacterium longum as an oral delivery system of endostatin for gene therapy on solid liver cancer
-
Fu GF, Li X, Hou YY, Fan YR, Liu WH Xu GX. Bifidobacterium longum as an oral delivery system of endostatin for gene therapy on solid liver cancer. Cancer Gene Ther 2005; 12: 133-140
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 133-140
-
-
Fu, G.F.1
Li, X.2
Hou, Y.Y.3
Fan, Y.R.4
Liu, W.H.5
Xu, G.X.6
-
123
-
-
14244267903
-
Endostatin gene therapy delivered by Salmonella choleraesuis in murine tumor models
-
Lee CH, Wu CL, Shiau AL. Endostatin gene therapy delivered by Salmonella choleraesuis in murine tumor models. J Gene Med 2004; 6: 1382-1393
-
(2004)
J Gene Med
, vol.6
, pp. 1382-1393
-
-
Lee, C.H.1
Wu, C.L.2
Shiau, A.L.3
-
124
-
-
13144262858
-
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
-
Goldman CK, Kendall RL, Cabrera G, Soroceanu L, Heike Y, Gillespie GY, Siegal GP, Mao X, Bett AJ, Huckle WR, Thomas KA, Curiel DT. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci USA 1998; 95: 8795-8800
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8795-8800
-
-
Goldman, C.K.1
Kendall, R.L.2
Cabrera, G.3
Soroceanu, L.4
Heike, Y.5
Gillespie, G.Y.6
Siegal, G.P.7
Mao, X.8
Bett, A.J.9
Huckle, W.R.10
Thomas, K.A.11
Curiel, D.T.12
-
125
-
-
13144254247
-
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
-
Lin P, Buxton JA, Acheson A, Radziejewski C, Maisonpierre PC, Yancopoulos GD, Channon KM, Hale LP, Dewhirst MW, George SE, Peters KG. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc Natl Acad Sci USA 1998; 95: 8829-8834
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8829-8834
-
-
Lin, P.1
Buxton, J.A.2
Acheson, A.3
Radziejewski, C.4
Maisonpierre, P.C.5
Yancopoulos, G.D.6
Channon, K.M.7
Hale, L.P.8
Dewhirst, M.W.9
George, S.E.10
Peters, K.G.11
-
126
-
-
0033538517
-
Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
-
Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, Benedict W, Bouck NP. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 1999, 285: 245-248
-
(1999)
Science
, vol.285
, pp. 245-248
-
-
Dawson, D.W.1
Volpert, O.V.2
Gillis, P.3
Crawford, S.E.4
Xu, H.5
Benedict, W.6
Bouck, N.P.7
-
127
-
-
3042700788
-
Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma
-
Matsumoto K, Ishikawa H, Nishimura D, Hamasaki K, Nakao K, Eguchi K. Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma. Hepatology 2004; 40: 252-259
-
(2004)
Hepatology
, vol.40
, pp. 252-259
-
-
Matsumoto, K.1
Ishikawa, H.2
Nishimura, D.3
Hamasaki, K.4
Nakao, K.5
Eguchi, K.6
-
128
-
-
24344491891
-
Suppression of metastasis of human pancreatic cancer to the liver by transportal injection of recombinant adenoviral NK4 in nude mice
-
Murakami M, Nagai E, Mizumoto K, Saimura M, Ohuchida K, Inadome N, Matsumoto K, Nakamura T, Maemondo M, Nukiwa T, Tanaka M. Suppression of metastasis of human pancreatic cancer to the liver by transportal injection of recombinant adenoviral NK4 in nude mice. Int J Cancer 2005; 117: 160-165
-
(2005)
Int J Cancer
, vol.117
, pp. 160-165
-
-
Murakami, M.1
Nagai, E.2
Mizumoto, K.3
Saimura, M.4
Ohuchida, K.5
Inadome, N.6
Matsumoto, K.7
Nakamura, T.8
Maemondo, M.9
Nukiwa, T.10
Tanaka, M.11
-
129
-
-
9144260053
-
IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice
-
Harada N, Shimada M, Okano S, Suehiro T, Soejima Y, Tomita Y, Maehara Y. IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice. J Immunol 2004; 173: 6635-6644
-
(2004)
J Immunol
, vol.173
, pp. 6635-6644
-
-
Harada, N.1
Shimada, M.2
Okano, S.3
Suehiro, T.4
Soejima, Y.5
Tomita, Y.6
Maehara, Y.7
-
130
-
-
0141941540
-
Viral oncolysis for malignant liver tumors
-
Mullen JT, Tanabe KK. Viral oncolysis for malignant liver tumors. Ann Surg Oncol 2003; 10: 596-605
-
(2003)
Ann Surg Oncol
, vol.10
, pp. 596-605
-
-
Mullen, J.T.1
Tanabe, K.K.2
-
131
-
-
28844444483
-
Recent progress in the battle between oncolytic viruses and tumours
-
Parato KA, Senger D, Forsyth PA, Bell JC. Recent progress in the battle between oncolytic viruses and tumours. Nat Rev Cancer 2005; 5: 965-976
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 965-976
-
-
Parato, K.A.1
Senger, D.2
Forsyth, P.A.3
Bell, J.C.4
-
132
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo J, Gomez-Manzano C, Alemany R, Lee PS, McDonnell TJ, Mitlianga P, Shi YX, Levin VA, Yung WK, Kyritsis AP. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 2000; 19: 2-12
-
(2000)
Oncogene
, vol.19
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
Lee, P.S.4
McDonnell, T.J.5
Mitlianga, P.6
Shi, Y.X.7
Levin, V.A.8
Yung, W.K.9
Kyritsis, A.P.10
-
133
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
-
Heise C, Hermiston T, Johnson L, Brooks G, Sampson-Johannes A, Williams A, Hawkins L, Kim D. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat Med 2000; 6: 1134-1139
-
(2000)
Nat Med
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
Brooks, G.4
Sampson-Johannes, A.5
Williams, A.6
Hawkins, L.7
Kim, D.8
-
134
-
-
27944471015
-
Development of transcriptionally regulated oncolytic adenoviruses
-
Ko D, Hawkins L, Yu DC. Development of transcriptionally regulated oncolytic adenoviruses. Oncogene 2005; 24: 7763-7774
-
(2005)
Oncogene
, vol.24
, pp. 7763-7774
-
-
Ko, D.1
Hawkins, L.2
Yu, D.C.3
-
135
-
-
0036901289
-
Oncolytic herpes simplex virus vectors for cancer virotherapy
-
Varghese S, Rabkin SD. Oncolytic herpes simplex virus vectors for cancer virotherapy. Cancer Gene Ther 2002; 9: 967-978
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 967-978
-
-
Varghese, S.1
Rabkin, S.D.2
-
136
-
-
0036785902
-
Regulation of herpes simplex virus 1 replication using tumor-associated promoters
-
discussion 512-513
-
Mullen JT, Kasuya H, Yoon SS, Carroll NM, Pawlik TM, Chandrasekhar S, Nakamura H, Donahue JM, Tanabe KK. Regulation of herpes simplex virus 1 replication using tumor-associated promoters. Ann Surg 2002; 236: 502-512; discussion 512-513
-
(2002)
Ann Surg
, vol.236
, pp. 502-512
-
-
Mullen, J.T.1
Kasuya, H.2
Yoon, S.S.3
Carroll, N.M.4
Pawlik, T.M.5
Chandrasekhar, S.6
Nakamura, H.7
Donahue, J.M.8
Tanabe, K.K.9
-
137
-
-
0036212495
-
Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5
-
Nakamura H, Kasuya H, Mullen JT, Yoon SS, Pawlik TM, Chandrasekhar S, Donahue JM, Chiocca EA, Chung RY, Tanabe KK. Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. J Clin Invest 2002;109:871-882
-
(2002)
J Clin Invest
, vol.109
, pp. 871-882
-
-
Nakamura, H.1
Kasuya, H.2
Mullen, J.T.3
Yoon, S.S.4
Pawlik, T.M.5
Chandrasekhar, S.6
Donahue, J.M.7
Chiocca, E.A.8
Chung, R.Y.9
Tanabe, K.K.10
-
138
-
-
0036903141
-
Armed therapeutic viruses: Strategies and challenges to arming oncolytic viruses with therapeutic genes
-
Hermiston TW, Kuhn I. Armed therapeutic viruses: strategies and challenges to arming oncolytic viruses with therapeutic genes. Cancer Gene Ther 2002; 9: 1022-1035
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 1022-1035
-
-
Hermiston, T.W.1
Kuhn, I.2
-
139
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M, Ng L, Nye JA, Sampson-Johannes A, Fattaey A, McCormick F. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996; 274: 373-376
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
Heise, C.4
Horn, S.5
Muna, M.6
Ng, L.7
Nye, J.A.8
Sampson-Johannes, A.9
Fattaey, A.10
McCormick, F.11
-
140
-
-
19944363519
-
Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
-
O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, Boyle L, Pandey K, Soria C, Kunich J, Shen Y, Habets G, Ginzinger D, McCormick F. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell 2004; 6: 611-623
-
(2004)
Cancer Cell
, vol.6
, pp. 611-623
-
-
O'Shea, C.C.1
Johnson, L.2
Bagus, B.3
Choi, S.4
Nicholas, C.5
Shen, A.6
Boyle, L.7
Pandey, K.8
Soria, C.9
Kunich, J.10
Shen, Y.11
Habets, G.12
Ginzinger, D.13
McCormick, F.14
-
141
-
-
0033199168
-
p53 selective and nonselective replication of an E1B-deleted adenovirus in hepatocellular carcinoma
-
Vollmer CM, Ribas A, Butterfield LH, Dissette VB, Andrews KJ, Eilber FC, Montejo LD, Chen AY, Hu B, Glaspy JA, McBride WH, Economou JS. p53 selective and nonselective replication of an E1B-deleted adenovirus in hepatocellular carcinoma. Cancer Res 1999; 59: 4369-4374
-
(1999)
Cancer Res
, vol.59
, pp. 4369-4374
-
-
Vollmer, C.M.1
Ribas, A.2
Butterfield, L.H.3
Dissette, V.B.4
Andrews, K.J.5
Eilber, F.C.6
Montejo, L.D.7
Chen, A.Y.8
Hu, B.9
Glaspy, J.A.10
McBride, W.H.11
Economou, J.S.12
-
142
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I, Arseneau J, Tannock IF, Romel L, Gore M, Ironside J, MacDougall RH, Heise C, Randlev B, Gillenwater AM, Bruso P, Kaye SB, Hong WK, Kim DH. a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000; 6: 879-885
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
Gore, M.7
Ironside, J.8
MacDougall, R.H.9
Heise, C.10
Randlev, B.11
Gillenwater, A.M.12
Bruso, P.13
Kaye, S.B.14
Hong, W.K.15
Kim, D.H.16
-
143
-
-
85047699490
-
Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma
-
Habib N, Salama H, Abd El Latif Abu Median A, Isac Anis I, Abd Al Aziz RA, Sarraf C, Mitry R, Havlik R, Seth P, Hartwigsen J, Bhushan R, Nicholls J, Jensen S. Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma. Cancer Gene Ther 2002; 9: 254-259
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 254-259
-
-
Habib, N.1
Salama, H.2
Abd El Latif Abu Median, A.3
Isac Anis, I.4
Abd Al Aziz, R.A.5
Sarraf, C.6
Mitry, R.7
Havlik, R.8
Seth, P.9
Hartwigsen, J.10
Bhushan, R.11
Nicholls, J.12
Jensen, S.13
-
144
-
-
0038518576
-
Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer
-
Hamid O, Varterasian ML, Wadler S, Hecht JR, Benson A 3rd, Galanis E, Uprichard M, Omer C, Bycott P, Hackman RC, Shields AF. Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21: 1498-1504
-
(2003)
J Clin Oncol
, vol.21
, pp. 1498-1504
-
-
Hamid, O.1
Varterasian, M.L.2
Wadler, S.3
Hecht, J.R.4
Benson III, A.5
Galanis, E.6
Uprichard, M.7
Omer, C.8
Bycott, P.9
Hackman, R.C.10
Shields, A.F.11
-
145
-
-
0037314655
-
Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies
-
Makower D, Rozenblit A, Kaufman H, Edelman M, Lane ME, Zwiebel J, Haynes H, Wadler S. Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies. Clin Cancer Res 2003, 9: 693-702
-
(2003)
Clin Cancer Res
, vol.9
, pp. 693-702
-
-
Makower, D.1
Rozenblit, A.2
Kaufman, H.3
Edelman, M.4
Lane, M.E.5
Zwiebel, J.6
Haynes, H.7
Wadler, S.8
-
146
-
-
0036828125
-
Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): Phase II viral, immunologic, and clinical endpoints
-
Reid T, Galanis E, Abbruzzese J, Sze D, Wein LM, Andrews J, Randlev B, Heise C, Uprichard M, Hatfield M Rome L, Rubin J, Kirn D. Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. Cancer Res 2002; 62: 6070-6079
-
(2002)
Cancer Res
, vol.62
, pp. 6070-6079
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
Sze, D.4
Wein, L.M.5
Andrews, J.6
Randlev, B.7
Heise, C.8
Uprichard, M.9
Hatfield, M.10
Rome, L.11
Rubin, J.12
Kirn, D.13
-
147
-
-
22944476168
-
Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin
-
Reid TR, Freeman S, Post L, McCormick F, Sze DY. Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther 2005; 12: 673-681
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 673-681
-
-
Reid, T.R.1
Freeman, S.2
Post, L.3
McCormick, F.4
Sze, D.Y.5
-
148
-
-
33644852717
-
China approves world's first oncolytic virus therapy for cancer treatment
-
Garber K. China approves world's first oncolytic virus therapy for cancer treatment. J Natl Cancer Inst 2006; 98: 298-300
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 298-300
-
-
Garber, K.1
-
149
-
-
0036112191
-
E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor
-
Takahashi M, Sato T, Sagawa T, Lu Y, Sato Y, Iyama S, Yamada Y, Fukaura J, Takahashi S, Miyanishi K, Yamashita T, Sasaki K, Kogawa K, Hammada H, Kato J, Niitsu Y. E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor. Mol Ther 2002; 5: 627-634
-
(2002)
Mol Ther
, vol.5
, pp. 627-634
-
-
Takahashi, M.1
Sato, T.2
Sagawa, T.3
Lu, Y.4
Sato, Y.5
Iyama, S.6
Yamada, Y.7
Fukaura, J.8
Takahashi, S.9
Miyanishi, K.10
Yamashita, T.11
Sasaki, K.12
Kogawa, K.13
Hammada, H.14
Kato, J.15
Niitsu, Y.16
-
150
-
-
0035417931
-
A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin
-
Li Y, Yu DC, Chen Y, Amin P, Zhang H, Nguyen N, Henderson DR. A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin. Cancer Res 2001; 61: 6428-6436
-
(2001)
Cancer Res
, vol.61
, pp. 6428-6436
-
-
Li, Y.1
Yu, D.C.2
Chen, Y.3
Amin, P.4
Zhang, H.5
Nguyen, N.6
Henderson, D.R.7
-
151
-
-
10344223982
-
Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter
-
Sagawa T, Takahashi M, Sato T, Sato Y, Lu Y, Sumiyoshi T, Yamada Y, Iyama S, Fukaura J, Sasaki K, Hamada H, Miyanishi K, Takayama T, Kato J, Niitsu Y. Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter. Mol Ther 2004; 10: 1043-1050
-
(2004)
Mol Ther
, vol.10
, pp. 1043-1050
-
-
Sagawa, T.1
Takahashi, M.2
Sato, T.3
Sato, Y.4
Lu, Y.5
Sumiyoshi, T.6
Yamada, Y.7
Iyama, S.8
Fukaura, J.9
Sasaki, K.10
Hamada, H.11
Miyanishi, K.12
Takayama, T.13
Kato, J.14
Niitsu, Y.15
-
152
-
-
0038745637
-
A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer
-
Wirth T, Zender L, Schulte B, Mundt B, Plentz R, Rudolph KL, Manns M, Kubicka S, Kuhnel F. A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer. Cancer Res 2003; 63: 3181-3188
-
(2003)
Cancer Res
, vol.63
, pp. 3181-3188
-
-
Wirth, T.1
Zender, L.2
Schulte, B.3
Mundt, B.4
Plentz, R.5
Rudolph, K.L.6
Manns, M.7
Kubicka, S.8
Kuhnel, F.9
-
153
-
-
0142010649
-
Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner
-
Kim E, Kim JH, Shin HY, Lee H, Yang JM, Kim J, Sohn JH, Kim H, Yun CO. Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner. Hum Gene Ther 2003; 14: 1415-1428
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1415-1428
-
-
Kim, E.1
Kim, J.H.2
Shin, H.Y.3
Lee, H.4
Yang, J.M.5
Kim, J.6
Sohn, J.H.7
Kim, H.8
Yun, C.O.9
-
154
-
-
0037379880
-
An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: Dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy
-
Jakubczak JL, Ryan P, Gorziglia M, Clarke L, Hawkins LK, Hay C, Huang Y, Kaloss M, Marinov A, Phipps S, Pinkstaff A, Shirley P, Skripchenko Y, Stewart D, Forry-Schaudies S, Hallenbeck PL. An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy. Cancer Res 2003; 63: 1490-1499
-
(2003)
Cancer Res
, vol.63
, pp. 1490-1499
-
-
Jakubczak, J.L.1
Ryan, P.2
Gorziglia, M.3
Clarke, L.4
Hawkins, L.K.5
Hay, C.6
Huang, Y.7
Kaloss, M.8
Marinov, A.9
Phipps, S.10
Pinkstaff, A.11
Shirley, P.12
Skripchenko, Y.13
Stewart, D.14
Forry-Schaudies, S.15
Hallenbeck, P.L.16
-
155
-
-
0037812877
-
In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF
-
Bristol JA, Zhu M, Ji H, Mina M, Xie Y, Clarke L, Forry-Schaudies S, Ennist DL. In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF. Mol Ther 2003; 7: 755-764
-
(2003)
Mol Ther
, vol.7
, pp. 755-764
-
-
Bristol, J.A.1
Zhu, M.2
Ji, H.3
Mina, M.4
Xie, Y.5
Clarke, L.6
Forry-Schaudies, S.7
Ennist, D.L.8
-
156
-
-
2342453303
-
A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases
-
Sova P, Ren XW, Ni S, Bernt KM, Mi J, Kiviat N, Lieber A. A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases. Mol Ther 2004; 9: 496-509
-
(2004)
Mol Ther
, vol.9
, pp. 496-509
-
-
Sova, P.1
Ren, X.W.2
Ni, S.3
Bernt, K.M.4
Mi, J.5
Kiviat, N.6
Lieber, A.7
-
157
-
-
2342519582
-
An oncolytic adenoviral vector of Smac increases antitumor activity of TRAIL against HCC in human cells and in mice
-
Pei Z, Chu L, Zou W, Zhang Z, Qiu S, Qi R, Gu J, Qian C, Liu X. An oncolytic adenoviral vector of Smac increases antitumor activity of TRAIL against HCC in human cells and in mice. Hepatology 2004; 39: 1371-1381
-
(2004)
Hepatology
, vol.39
, pp. 1371-1381
-
-
Pei, Z.1
Chu, L.2
Zou, W.3
Zhang, Z.4
Qiu, S.5
Qi, R.6
Gu, J.7
Qian, C.8
Liu, X.9
-
158
-
-
1842864085
-
An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy
-
Zhang ZL, Zou WG, Luo CX, Li BH, Wang JH, Sun LY, Qian QJ, Liu XY. An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy. Cell Res 2003; 13: 481-489
-
(2003)
Cell Res
, vol.13
, pp. 481-489
-
-
Zhang, Z.L.1
Zou, W.G.2
Luo, C.X.3
Li, B.H.4
Wang, J.H.5
Sun, L.Y.6
Qian, Q.J.7
Liu, X.Y.8
-
159
-
-
13944269593
-
Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocellular carcinoma
-
Li GC, Yang JM, Nie MM, Su CG, Sun LC, Qian YZ, Fang GE, Sham J, Wu MC, Qian QJ. Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocellular carcinoma. Chin Med J (Engl) 2005; 118: 179-185
-
(2005)
Chin Med J (Engl)
, vol.118
, pp. 179-185
-
-
Li, G.C.1
Yang, J.M.2
Nie, M.M.3
Su, C.G.4
Sun, L.C.5
Qian, Y.Z.6
Fang, G.E.7
Sham, J.8
Wu, M.C.9
Qian, Q.J.10
-
160
-
-
26844496786
-
HSV-1-derived recombinant and amplicon vectors for gene transfer and gene therapy
-
Epstein AL, Marconi P, Argnani R, Manservigi R. HSV-1-derived recombinant and amplicon vectors for gene transfer and gene therapy. Curr Gene Ther 2005; 5: 445-458
-
(2005)
Curr Gene Ther
, vol.5
, pp. 445-458
-
-
Epstein, A.L.1
Marconi, P.2
Argnani, R.3
Manservigi, R.4
-
161
-
-
0034082389
-
Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer
-
Bennett JJ, Kooby DA, Delman K, McAuliffe P, Halterman MW, Federoff H, Fong Y. Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer. J Mol Med 2000; 78: 166-174
-
(2000)
J Mol Med
, vol.78
, pp. 166-174
-
-
Bennett, J.J.1
Kooby, D.A.2
Delman, K.3
McAuliffe, P.4
Halterman, M.W.5
Federoff, H.6
Fong, Y.7
-
162
-
-
33646040377
-
Oncolytic herpes viral therapy is effective in the treatment of hepatocellular carcinoma cell lines
-
Song TJ, Eisenberg DP, Adusumilli PS, Hezel M, Fong Y. Oncolytic herpes viral therapy is effective in the treatment of hepatocellular carcinoma cell lines. J Gastrointest Surg 2006; 10: 532-542
-
(2006)
J Gastrointest Surg
, vol.10
, pp. 532-542
-
-
Song, T.J.1
Eisenberg, D.P.2
Adusumilli, P.S.3
Hezel, M.4
Fong, Y.5
-
163
-
-
0036841571
-
Comparison of safety, delivery, and efficacy of two oncolytic herpes viruses (G207 and NV1020) for peritoneal cancer
-
Bennett JJ, Delman KA, Burt BM, Mariotti A, Malhotra S, Zager J, Petrowsky H, Mastorides S, Federoff H, Fong Y. Comparison of safety, delivery, and efficacy of two oncolytic herpes viruses (G207 and NV1020) for peritoneal cancer. Cancer Gene Ther 2002; 9: 935-945
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 935-945
-
-
Bennett, J.J.1
Delman, K.A.2
Burt, B.M.3
Mariotti, A.4
Malhotra, S.5
Zager, J.6
Petrowsky, H.7
Mastorides, S.8
Federoff, H.9
Fong, Y.10
-
164
-
-
0036721374
-
Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene
-
Pawlik TM, Nakamura H, Mullen JT, Kasuya H, Yoon SS, Chandrasekhar S, Chiocca EA, Tanabe KK. Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene. Cancer 2002; 95: 1171-1181
-
(2002)
Cancer
, vol.95
, pp. 1171-1181
-
-
Pawlik, T.M.1
Nakamura, H.2
Mullen, J.T.3
Kasuya, H.4
Yoon, S.S.5
Chandrasekhar, S.6
Chiocca, E.A.7
Tanabe, K.K.8
-
165
-
-
0035878715
-
Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil
-
Nakamura H, Mullen JT, Chandrasekhar S, Pawlik TM, Yoon SS, Tanabe KK. Multimodality therapy with a replication-conditional herpes simplex virus 1 mutant that expresses yeast cytosine deaminase for intratumoral conversion of 5-fluorocytosine to 5-fluorouracil. Cancer Res 2001; 61: 5447-5452
-
(2001)
Cancer Res
, vol.61
, pp. 5447-5452
-
-
Nakamura, H.1
Mullen, J.T.2
Chandrasekhar, S.3
Pawlik, T.M.4
Yoon, S.S.5
Tanabe, K.K.6
-
166
-
-
0037345805
-
Neoadjuvant treatment of hepatic malignancy: An oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects against recurrence-after resection
-
Jarnagin WR, Zager JS, Klimstra D, Delman KA, Malhotra S, Ebright M, Little S, DeRubertis B, Stanziale SF, Hezel M, Federoff H, Fong Y. Neoadjuvant treatment of hepatic malignancy: an oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects against recurrence-after resection. Cancer Gene Ther 2003; 10: 215-223
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 215-223
-
-
Jarnagin, W.R.1
Zager, J.S.2
Klimstra, D.3
Delman, K.A.4
Malhotra, S.5
Ebright, M.6
Little, S.7
DeRubertis, B.8
Stanziale, S.F.9
Hezel, M.10
Federoff, H.11
Fong, Y.12
-
167
-
-
1642443434
-
Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus
-
Shinozaki K, Ebert O, Kournioti C, Tai YS, Woo SL. Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus. Mol Ther 2004; 9: 368-376
-
(2004)
Mol Ther
, vol.9
, pp. 368-376
-
-
Shinozaki, K.1
Ebert, O.2
Kournioti, C.3
Tai, Y.S.4
Woo, S.L.5
-
168
-
-
27144515258
-
Prophylactic alpha interferon treatment increases the therapeutic index of oncolytic vesicular stomatitis virus virotherapy for advanced hepatocellular carcinoma in immune-competent rats
-
Shinozaki K, Ebert O, Suriawinata A, Thung SN, Woo SL. Prophylactic alpha interferon treatment increases the therapeutic index of oncolytic vesicular stomatitis virus virotherapy for advanced hepatocellular carcinoma in immune-competent rats. J Virol 2005; 79: 13705-13713
-
(2005)
J Virol
, vol.79
, pp. 13705-13713
-
-
Shinozaki, K.1
Ebert, O.2
Suriawinata, A.3
Thung, S.N.4
Woo, S.L.5
|