Importance, mechanisms and limitations of the distant bystander effect in cancer gene therapy of experimental liver tumors

Cancer Letters

Volumn 179, Issue 1, 2002, Pages 59-69

  Engelmann, Carsten ^a,b,f   Heslan, Jean Marie ^c   Fabre, Monique ^d   Lagarde, Jean Pierre ^b   Klatzmann, David ^b   Panis, Yves ^a,e  

^a Hôpital Cochin ^*  (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c HÔTEL DIEU   (France)

^d BICÊTRE HOSPITAL   (France)

^e HÔPITAL LARIBOISIÈRE   (France)

^f HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Distant bystander effect; Ganciclovir; Liver metastases; Suicide gene

Indexed keywords

ADENOVIRUS VECTOR; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GANCICLOVIR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BYSTANDER EFFECT; CANCER GROWTH; CANCER SIZE; CANCER TRANSPLANTATION; CELL INFILTRATION; CONTROLLED STUDY; EXPERIMENTAL NEOPLASM; GENE THERAPY; HEPATOMA CELL; HERPES SIMPLEX VIRUS; IMMUNOMODULATION; ISOGRAFT; LIVER CELL CARCINOMA; LYMPHOCYTE CLONE; MALE; MONOCYTE; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SUICIDE GENE; T LYMPHOCYTE;

ADENOVIRIDAE; ANIMALS; ANTIVIRAL AGENTS; APOPTOSIS; BYSTANDER EFFECT; CARCINOMA, HEPATOCELLULAR; CYTOKINES; GENE THERAPY; GENE TRANSFER TECHNIQUES; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS, EXPERIMENTAL; LYMPHOCYTES; PHENOTYPE; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, ANTIGEN, T-CELL; THYMIDINE KINASE;

EID: 0037042181     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00854-0     Document Type: Article

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