-
1
-
-
0033052318
-
Synthetic oligonucleotides: The development of antisense therapeutics
-
Monteith, D. K. and Levin, A. A. (1999) Synthetic oligonucleotides: the development of antisense therapeutics. Toxicol. Pathol. 27, 8-13.
-
(1999)
Toxicol. Pathol.
, vol.27
, pp. 8-13
-
-
Monteith, D.K.1
Levin, A.A.2
-
2
-
-
0033958635
-
Antisense therapeutics: Is it as simple as complementary base recognition?
-
Agrawal, S. and Kandimalla, E. R. (2000) Antisense therapeutics: Is it as simple as complementary base recognition? Mol. Med. Today 6, 72-78.
-
(2000)
Mol. Med. Today
, vol.6
, pp. 72-78
-
-
Agrawal, S.1
Kandimalla, E.R.2
-
4
-
-
0032853334
-
Antisense oligonucleotides as therapeutic agents
-
Galderisi, U., Cascino, A., and Giordano, A. (1999) Antisense oligonucleotides as therapeutic agents. J. Cell Physiol. 181, 251-257.
-
(1999)
J. Cell Physiol.
, vol.181
, pp. 251-257
-
-
Galderisi, U.1
Cascino, A.2
Giordano, A.3
-
5
-
-
0034018086
-
Is irrelevant cleavage the price of antisense efficacy?
-
Stein, C. A. (2000) Is irrelevant cleavage the price of antisense efficacy? Pharmacel. Ther. 85, 231-236.
-
(2000)
Pharmacel. Ther.
, vol.85
, pp. 231-236
-
-
Stein, C.A.1
-
6
-
-
0032697941
-
Two problems in antisense biotechnology: In vitro delivery and the design of antisense experiments
-
Stein, C. A. (1999) Two problems in antisense biotechnology: in vitro delivery and the design of antisense experiments. Biochim. Biophys. 1489, 45-52.
-
(1999)
Biochim. Biophys.
, vol.1489
, pp. 45-52
-
-
Stein, C.A.1
-
7
-
-
0027732877
-
Immunotoxins and recombinant toxins in the treatment of solid carcinomas
-
Theuer, C. P. and Pastan I. (1993) Immunotoxins and recombinant toxins in the treatment of solid carcinomas. Am. J. Surg. 166, 284-288.
-
(1993)
Am. J. Surg.
, vol.166
, pp. 284-288
-
-
Theuer, C.P.1
Pastan, I.2
-
8
-
-
0026005994
-
B3-(Fv)-PE38KDEL, a single chain immunotoxin that causes complete regression of a human carcinoma in mice
-
Brinkmann, U., Pai, L. H., and FitzGerald, D. J. (1991) B3-(Fv)-PE38KDEL, a single chain immunotoxin that causes complete regression of a human carcinoma in mice. Proc. Natl. Acad. Sci. USA 88, 8616-8620.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8616-8620
-
-
Brinkmann, U.1
Pai, L.H.2
FitzGerald, D.J.3
-
9
-
-
0032505742
-
Generically engineered antibodies in gene transfer and gene therapy
-
Pelegrin, M., Merin, M., Noel, D., and Piechaczyk, M. (1998) Generically engineered antibodies in gene transfer and gene therapy. Hum. Gen. Ther. 9, 2165-2175.
-
(1998)
Hum. Gen. Ther.
, vol.9
, pp. 2165-2175
-
-
Pelegrin, M.1
Merin, M.2
Noel, D.3
Piechaczyk, M.4
-
10
-
-
0031016269
-
Intrabodies: Turning the humoral immune system outside in for intracellular immunization
-
Marasco, W. (1997) Intrabodies: turning the humoral immune system outside in for intracellular immunization. Gene Ther. 4, 11-15.
-
(1997)
Gene Ther.
, vol.4
, pp. 11-15
-
-
Marasco, W.1
-
11
-
-
0029114769
-
Intracellular antibodies: Development and therapeutic potential
-
Richardson, J. H. and Marasco, W. A. (1995) Intracellular antibodies: development and therapeutic potential. Trends Biotech. 13, 306-310.
-
(1995)
Trends Biotech.
, vol.13
, pp. 306-310
-
-
Richardson, J.H.1
Marasco, W.A.2
-
12
-
-
0024299563
-
Intracellular immunization
-
Baltimore, D. (1988) Intracellular immunization. Nature 335, 395-396.
-
(1988)
Nature
, vol.335
, pp. 395-396
-
-
Baltimore, D.1
-
13
-
-
0031039221
-
Targeting vectors for intracellular immunization
-
Persic, L., Righi, M., Roberts, A., Hoogenboom, H. R., Cattaneo, A., and Bradbury, A. (1997) Targeting vectors for intracellular immunization. Gene 187, 1-8.
-
(1997)
Gene
, vol.187
, pp. 1-8
-
-
Persic, L.1
Righi, M.2
Roberts, A.3
Hoogenboom, H.R.4
Cattaneo, A.5
Bradbury, A.6
-
14
-
-
0034203953
-
Clinical studies of antisense therapy in cancer
-
Yuen, A. R. and Sikic, B. I. (2000) Clinical studies of antisense therapy in cancer. Front. Biosci. 5, D588-593.
-
(2000)
Front. Biosci.
, vol.5
, pp. D588-D593
-
-
Yuen, A.R.1
Sikic, B.I.2
-
15
-
-
0032774070
-
A role for intracellular immunization in chemosensitization of tumor cells?
-
Pich, A. and Rancour, T. C. (1999) A role for intracellular immunization in chemosensitization of tumor cells? Gene Ther. 6, 1202-1209.
-
(1999)
Gene Ther.
, vol.6
, pp. 1202-1209
-
-
Pich, A.1
Rancour, T.C.2
-
16
-
-
0027275371
-
Design, intracellular expression, and activity of human anti-human immunodeficiency virus type 1 gp120 single-chain antibody
-
Marasco, W. A., Haseltine, W. A., and Chen, S-Y. (1993) Design, intracellular expression, and activity of human anti-human immunodeficiency virus type 1 gp120 single-chain antibody. Proc. Natl. Acad. Sci. USA 90, 7889-7893.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7889-7893
-
-
Marasco, W.A.1
Haseltine, W.A.2
Chen, S.-Y.3
-
17
-
-
0032551588
-
Intracellular antibodies against HIV-1 envelope proteins for AIDS gene therapy
-
Marasco, W. A., Chen, S-Y., Richardson, J. H., Ramstedt, U., and Jones, S. D. (1998) Intracellular antibodies against HIV-1 envelope proteins for AIDS gene therapy. Hum. Gen. Ther. 8, 1627-1642.
-
(1998)
Hum. Gen. Ther.
, vol.8
, pp. 1627-1642
-
-
Marasco, W.A.1
Chen, S.-Y.2
Richardson, J.H.3
Ramstedt, U.4
Jones, S.D.5
-
18
-
-
0032521206
-
Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression
-
Cochet, O., Kenigsburg, M., Delumeau, I., et al. (1998) Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression. Cancer Res. 58, 1170-1176.
-
(1998)
Cancer Res.
, vol.58
, pp. 1170-1176
-
-
Cochet, O.1
Kenigsburg, M.2
Delumeau, I.3
-
19
-
-
0028500163
-
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines
-
Deshane, J., Loechel, F., Conry, R. M., Siegal, G. P., King, C. R., and Curiel, D. T. (1994) Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines. Gen. Ther. 1, 332-337.
-
(1994)
Gen. Ther.
, vol.1
, pp. 332-337
-
-
Deshane, J.1
Loechel, F.2
Conry, R.M.3
Siegal, G.P.4
King, C.R.5
Curiel, D.T.6
-
20
-
-
0028839655
-
Targeted tumor killing via an intracellular antibody against erbB-2
-
Deshane, J., Siegal, G. P., Alvarez, R. D., et al. (1995) Targeted tumor killing via an intracellular antibody against erbB-2. J. Clin. Invest. 96, 2980-2989.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2980-2989
-
-
Deshane, J.1
Siegal, G.P.2
Alvarez, R.D.3
-
21
-
-
0030101361
-
Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis
-
Deshane, J., Grim, J., Loechel, S., Siegal, G. P., Alvarez, R. D., and Curiel, D. T. (1996) Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis. Cancer Gene Therapy 3, 89-98.
-
(1996)
Cancer Gene Therapy
, vol.3
, pp. 89-98
-
-
Deshane, J.1
Grim, J.2
Loechel, S.3
Siegal, G.P.4
Alvarez, R.D.5
Curiel, D.T.6
-
22
-
-
0033779619
-
Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target
-
Arafat, W., Gomez-Navarro, J., Xiang, J., Siegal, G. P., Alvarez, R. D., and Curiel, D. T. (2000) Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target. Cancer Gene Ther. 7, 1250-1256.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1250-1256
-
-
Arafat, W.1
Gomez-Navarro, J.2
Xiang, J.3
Siegal, G.P.4
Alvarez, R.D.5
Curiel, D.T.6
-
23
-
-
0029893166
-
Novel gene therapy strategy to accomplish growth factor modualtion induces enhanced tumor cell chemosensitivity
-
Barnes, D. M., Deshane, J., Siegal, G. P., Alvarez, R. D., and Curiel, D. T. (1996) Novel gene therapy strategy to accomplish growth factor modualtion induces enhanced tumor cell chemosensitivity. Clin. Cancer Res. 2, 1089-1095.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1089-1095
-
-
Barnes, D.M.1
Deshane, J.2
Siegal, G.P.3
Alvarez, R.D.4
Curiel, D.T.5
-
24
-
-
0030935529
-
An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2
-
Wright, M., Grim, J., Kim, M., Strong, T. V., Siegal, G. P., and Curiel, D. T. (1997) An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2. Gene Therapy 4, 317-322.
-
(1997)
Gene Therapy
, vol.4
, pp. 317-322
-
-
Wright, M.1
Grim, J.2
Kim, M.3
Strong, T.V.4
Siegal, G.P.5
Curiel, D.T.6
-
25
-
-
16944364446
-
A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow
-
Kim, M., Wright, M., Deshane, J., et al. (1997) A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow. Hum. Gene Ther. 8, 157-170.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 157-170
-
-
Kim, M.1
Wright, M.2
Deshane, J.3
-
26
-
-
18544408628
-
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): A phase I trial
-
Alvarez, R. D., Barnes, M. N., Gomez-Navarro, J., et al. (2000) A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial. Clin. Cancer Res. 6, 3081-3087.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3081-3087
-
-
Alvarez, R.D.1
Barnes, M.N.2
Gomez-Navarro, J.3
-
27
-
-
0029844521
-
Phage libraries - A new route to clinically useful antibodies
-
Marks, C. and Marks, J. D. (1996) Phage libraries - a new route to clinically useful antibodies. New Engl. J. Med. 335, 730-733.
-
(1996)
New Engl. J. Med.
, vol.335
, pp. 730-733
-
-
Marks, C.1
Marks, J.D.2
-
28
-
-
0031909224
-
Production of a single cahin anti-CEA antibody from the hybridoma cell line T84. 66 using a modified colony-lift selection procedure to detect antigen-positive scFv bacterial clones
-
Rodenburg, C., Mernaugh, R., Bilbao, G., and Khazaeli M. B. (1998) Production of a single cahin anti-CEA antibody from the hybridoma cell line T84. 66 using a modified colony-lift selection procedure to detect antigen-positive scFv bacterial clones. Hybridoma 17, 1-8.
-
(1998)
Hybridoma
, vol.17
, pp. 1-8
-
-
Rodenburg, C.1
Mernaugh, R.2
Bilbao, G.3
Khazaeli, M.B.4
|