Proprotein convertases: Lessons from knockouts

FASEB Journal

Volumn 20, Issue 12, 2006, Pages 1954-1963

  Scamuffa, Nathalie ^a,b   Calvo, Fabien ^a,b   Chrétien, Michel ^c   Seidah, Nabil G ^d   Khatib, Abdel Majid ^a  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF OTTAWA   (Canada)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Abnormal embryonic development; Cellular proliferation; Dyslipidemias; Hormonal disorder; Human patients; Infertility

Indexed keywords

AMINO ACID; BACTERIAL TOXIN; FURIN; GLYCOPROTEIN; GROWTH FACTOR; ISOENZYME; KEXIN; NEURAL APOPTOSIS REGULATED CONVERTASE 1; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 3; PROPROTEIN CONVERTASE 4; PROPROTEIN CONVERTASE 5; PROPROTEIN CONVERTASE 6; PROPROTEIN CONVERTASE 7; SERINE PROTEINASE; SUBTILISIN; SUBTILISIN KEXIN LIKE ISOZYME 1;

ATHEROSCLEROSIS; CANCER; DEGENERATIVE DISEASE; DIABETES MELLITUS; EMBRYO DEVELOPMENT; ENDOCRINE DISEASE; ENZYME ACTIVITY; GENE DISRUPTION; INFERTILITY; KNOCKOUT MOUSE; LIPID METABOLISM; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; REVIEW; STEROL METABOLISM; ANIMAL; CARDIOVASCULAR SYSTEM; DRUG ANTAGONISM; EMBRYO; ENZYME SPECIFICITY; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; HEART DISEASE; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PRENATAL DEVELOPMENT;

BACTERIA (MICROORGANISMS); RODENTIA;

ANIMALS; CARDIOVASCULAR SYSTEM; EMBRYO; HEART DISEASES; MICE; MICE, KNOCKOUT; PROPROTEIN CONVERTASES; SUBSTRATE SPECIFICITY;

EID: 33750109567     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-5491rev     Document Type: Review

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