Limited redundancy of the proprotein convertase furin in mouse liver

Journal of Biological Chemistry

Volumn 279, Issue 51, 2004, Pages 53442-53450

  Roebroek, Anton J M ^a   Taylor, Neil A ^a   Louagie, Els ^a   Pauli, Ilse ^a   Smeijers, Liesbeth ^a   Snellinx, An ^a   Lauwers, Annick ^a   Van De Ven, Wim J M ^a   Hartmann, Dieter ^a   Creemers, John W M ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; HISTOLOGY; INSULIN; LIVING SYSTEMS STUDIES; MATHEMATICAL MODELS; PATHOLOGY; PHYSIOLOGY; TUMORS;

MAMMALIAN MODEL SYSTEM; PROPROTEIN CONVERTASE FURIN; REGULATORY PROTEINS;

ENZYMES;

ALBUMIN; ALPHA 1 MICROGLOBULIN; ALPHA5 INTEGRIN; FURIN; INSULIN RECEPTOR; INTERFERON; LIPOPROTEIN RECEPTOR RELATED PROTEIN; PROTEIN; ULINASTATIN; UNCLASSIFIED DRUG; VITRONECTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME SUBSTRATE; EXON; HISTOLOGY; KNOCKOUT MOUSE; LIVER; MODEL; MORPHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; TRANSGENIC MOUSE;

ALBUMINS; ALLELES; ALPHA-GLOBULINS; AMINO ACID MOTIFS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FURIN; GENOTYPE; IMMUNOHISTOCHEMISTRY; INTEGRIN ALPHA5; LIVER; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, GENETIC; NEOPLASMS; PHENOTYPE; PROPROTEIN CONVERTASES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LDL; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TRANSGENES; TRYPSIN INHIBITOR, KUNITZ SOYBEAN; VITRONECTIN;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 19944414287     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407152200     Document Type: Article

References (45)

1. Thomas, G. (2002) Nat. Rev Mol. Cell. Biol. 3, 753-766
2. Seidah, N. G., and Prat, A. (2002) Essays Biochem. 38, 79-94
3. Rockwell, N. C., Krysan, D. J., Komiyama, T., and Fuller, R. S. (2002) Chem. Rev. 102, 4525-4548
4. Seidah, N. G., Benjannet, S., Wickham, L., Marcinkiewicz, J., Jasmin, S. B., Stifani, S., Basak, A., Prat, A., and Chretien, M. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 928-933
5. Taylor, N. A., Van De Ven, W. J., and Creemers, J. W. (2003) FASEB J. 17, 1215-1227
6. Zhu, X., Zhou, A., Dey, A., Norrbom, C., Carroll, R., Zhang, C., Laurent, V., Lindberg, I., Ugleholdt, R., Holst, J. J., and Steiner, D. F. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10293-10298
7. Furuta, M., Yano, H., Zhou, A., Rouille, Y., Hoist, J. J., Carroll, R., Ravazzola, M., Orci, L., Furuta, H., and Steiner, D. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6646-6651
8. Jackson, R. S., Creemers, J. W., Ohagi, S., Raffin-Sanson, M. L., Sanders, L., Montague, C. T., Button, J. C., and O'Rahilly, S. (1997) Nat. Genet. 16, 303-306
9. Jackson, R. S., Creemers, J. W., Farooqi, I. S., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J., Lindley, K. J., and O'Rahilly, S. (2003) J. Clin. Invest. 112, 1550-1560
10. Li, M., Mbikay, M., and Arimura, A. (2000) Endocrinology 141, 3723-3730
11. Mbikay, M., Tadros, H., Ishida, N., Lerner, C. P., De Lamirande, E., Chen, A., El-Alfy, M., Clermont, Y., Seidah, N. G., Chretien, M., Gagnon, C., and Simpson, E. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6842-6846
12. Villeneuve, P., Feliciangeli, S., Croissandeau, G., Seidah, N. G., Mbikay, M., Kitabgi, P., and Beaudet, A. (2002) J. Neurochem. 82, 783-793
13. Constam, D. B., and Robertson, E. J. (2000) Genes Dev. 14, 1146-1155
14. Roebroek, A. J., Umans, L., Pauli, I. G., Robertson, E. J., van Leuven, F., Van de Yen, W. J., and Constam, D. B. (1998) Development (Camb.) 125, 4863-4876
15. Beck, S., Le Good, J. A., Guzman, M., Ben Haim, N., Roy, K., Beermann, F., and Constam, D. B. (2002) Nat. Cell Biol. 4, 981-985
16. Doetschman, T., Gregg, R. G., Maeda, N., Hooper, M. L., Melton, D. W., Thompson, S., and Smithies, O. (1987) Nature 330, 576-578
17. Torres, R. M., and Kühn, R. (1997) Laboratory Protocols for Conditional Gene Targeting, Oxford University Press, Oxford
18. Lallemand, Y., Luria, V., Haffner-Krausz, R., and Lonai, P. (1998) Transgenic Res. 7, 105-112
19. Kuhn, R., Schwenk, F., Aguet, M., and Rajewsky, K. (1995) Science 269, 1427-1429
20. Creemers, J. W., Roebroek, A. J., and Van de Ven, W. J. (1992) FEBS Lett. 300, 82-88
21. Creemers, J. W., Ines Dominguez, D., Plets, E., Serneels, L., Taylor, N. A., Multhaup, G., Craessaerts, K., Annaert, W., and De Strooper, B. (2001) J. Biol. Chem. 276, 4211-4217
22. Bailyes, E. M., Nave, B. T., Soos, M. A., Orr, S. R., Hayward, A. C., and Siddle, K. (1997) Biochem. J. 327, 209-215
23. Umans, L., Serneels, L., Lorent, K., Dewachter, I., Tesseur, I., Moechars, D., and Van Leuven, F. (1999) Neuroscience 94, 315-321
24. Lissitzky, J. C., Luis, J., Munzer, J. S., Benjannet, S., Parat, F., Chretien, M., Marvaldi, J., and Seidah, N. G. (2000) Biochem. J. 346, 133-138
25. Willnow, T. E., Moehring, J. M., Inocencio, N. M., Moehring, T. J., and Herz, J. (1996) Biochem. J. 313, 71-76
26. Brennan, S. O., and Nakayama, K. (1994) FEBS Lett. 338, 147-151
27. Bratt, T., Cedervall, T., and Akerstrom, B. (1994) FEBS Lett. 354, 57-61
28. Seger, D., and Shaltiel, S. (2000) FEBS Lett. 480, 169-174
29. Wouters, S., Leruth, M., Decroly, E., Vandenbranden, M., Creemers, J. W., van de Loo, J. W., Ruysschaert, J. M., and Courtoy, P. J. (1998) Biochem. J. 336, 311-316
30. Seidah, N. G., Chretien, M., and Day, R. (1994) Biochimie (Paris) 76, 197-209
31. Li, M., Shuto, Y., Somogyvari-Vigh, A., and Arimura, A. (1999) Neuroendocrinology 69, 217-226
32. Robertson, B. J., Moehring, J. M., and Moehring, T. J. (1993) J. Biol. Chem. 268, 24274-24277
33. Bravo, D. A., Gleason, J. B., Sanchez, R. I., Roth, R. A., and Fuller, R. S. (1994) J. Biol. Chem. 269, 25830-25837
34. Sucic, J. F., Moehring, J. M., Inocencio, N. M., Luchini, J. W., and Moehring, T. J. (1999) Biochem. J. 339, 639-647
35. Williams, J. F., McClain, D. A., Dull, T. J., Ullrich, A., and Olefsky, J. M. (1990) J. Biol. Chem. 265, 8463-8469
36. Michael, M. D., Kulkarni, R. N., Postic, C., Previs, S. F., Shulman, G. I., Magnuson, M. A., and Kahn, C. R. (2000) Mol. Cell 6, 87-97
37. Ko, K. W., McLeod, R. S., Avramoglu, R. K., Nimpf, J., FitzGerald, D. J., Vukmirica, J., and Yao, Z. (1998) J. Biol. Chem. 273, 27779-27785
38. Brennan, S. O. (1989) Mol. Biol. Med. 6, 87-92
39. Mori, K., Imamaki, A., Nagata, K., Yonetomi, Y., Kiyokage-Yoshimoto, R., Martin, T. J., Gillespie, M. T., Nagahama, M., Tsuji, A., and Matsuda, Y. (1999) J. Biochem. (Tokyo) 125, 627-633
40. Misumi, Y., Oda, K., Fujiwara, T., Takami, N., Tashiro, K., and Ikehara, Y. (1991) J. Biol. Chem. 266, 16954-16959
41. Duckert, P., Brunak, S., and Blom, N. (2004) Protein Eng. Des. Sel. 17, 107-112
42. Holyoak, T., Kettner, C. A., Petsko, G. A Fuller, R. S., and Ringe, D. (2004) Biochemistry 43, 2412-2421
43. Khatib, A. M., Siegfried, G., Chretien, M., Metrakos, P., and Seidah, N. G. (2002) Am. J. Pathol. 160, 1921-1935
44. Sarac, M. S., Peinado, J. R., Leppla, S. H., and Lindberg, I. (2004) Infect. Immun. 72, 602-605
45. Sarac, M. S., Cameron, A., and Lindberg, I. (2002) Infect. Immun. 70, 7136-7139