Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases

Oncogene

Volumn 24, Issue 46, 2005, Pages 6925-6935

  Siegfried, Geraldine ^a   Basak, Ajoy ^b   Prichett Pejic, Wendy ^b   Scamuffa, Nathalie ^b   Ma, Liming ^b   Benjannet, Suzanne ^a   Veinot, John P ^b   Calvo, Fabien ^c   Seidah, Nabil ^a   Khatib, Abdel Majid ^b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c INSERM   (France)

Author keywords

PDGF B; Processing; Proprotein convertases; Prosegments; Secretion

Indexed keywords

ALANYLARGINYLPROLYLVALYLTHREONINE; AMINO ACID DERIVATIVE; ARGINYLGLYCYLARGINYLARGININE; DIMER; FURIN; ISOENZYME; PEPTIDE; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PROPROTEIN CONVERTASE 5; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN; CELL SURFACE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIGESTION; DRUG MECHANISM; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DIMERIZATION; DNA PRIMERS; FURIN; HUMANS; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; MICE; MOLECULAR SEQUENCE DATA; PROPROTEIN CONVERTASES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-SIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 27144488288     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208838     Document Type: Article

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