A systematic analysis of disease-associated variants in the 3′ regulatory regions of human protein-coding genes II: The importance of mRNA secondary structure in assessing the functionality of 3′ UTR variants

Human Genetics

Volumn 120, Issue 3, 2006, Pages 301-333

  Chen, Jian Min ^a,b,c   Férec, Claude ^a,b,c,d   Cooper, David N ^e  

^a INSERM   (France)

^b ETABLISSEMENT FRANÇAIS DU SANG   (France)

^c FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

^d CHU MORVAN   (France)

^e CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; ANTINEOPLASTIC AGENT; APOLIPOPROTEIN A5; BONE MORPHOGENETIC PROTEIN 2; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; FLUOROURACIL; GENE PRODUCT; GLUCOCORTICOID RECEPTOR; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 4; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HISTONE; INTERLEUKIN 12; MESSENGER RNA; MICRORNA; NATRIURETIC PEPTIDE TYPE C; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3; PROTEIN HBB; PYRIMIDINE; SELENOCYSTEINE; SELENOPROTEIN; SELENOPROTEIN 15; SELENOPROTEIN N1; SLIT PROTEIN; SOMATOMEDIN B; STROMAL CELL DERIVED FACTOR 1; THYMIDYLATE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; BETA THALASSEMIA; CANCER SUSCEPTIBILITY; CELLULAR DISTRIBUTION; CODON USAGE; CONFORMATIONAL TRANSITION; DISEASE ASSOCIATION; DISEASE MARKER; DNA FLANKING REGION; DRUG SENSITIVITY; ESOPHAGUS CARCINOMA; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE INSERTION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE SEQUENCE; GENETIC DISORDER; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; GILLES DE LA TOURETTE SYNDROME; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN GENETICS; IN VITRO STUDY; INSULIN RESISTANCE; IRON RESPONSIVE ELEMENT; MUSCULAR DYSTROPHY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN SECONDARY STRUCTURE; REPORTER GENE; REVIEW; RNA CLEAVAGE; RNA DEGRADATION; RNA STRUCTURE; STOMACH CANCER; SYSTEMATIC REVIEW; TRANSCRIPTION REGULATION;

3' UNTRANSLATED REGIONS; BASE COMPOSITION; BASE SEQUENCE; GENETIC DISEASES, INBORN; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OPEN READING FRAMES; POLYMORPHISM, SINGLE NUCLEOTIDE; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER;

EID: 33748747485     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-006-0218-x     Document Type: Review

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