Human histamine N-methyltransferase pharmacogenetics: Common genetic polymorphisms that alter activity

Molecular Pharmacology

Volumn 53, Issue 4, 1998, Pages 708-717

  Preuss, Charles V ^a   Wood, Thomas C ^a   Szumlanski, Carol L ^a   Raftogianis, Rebecca B ^a   Otterness, Diane M ^a   Girard, Blanka ^a   Scott, Mary C ^a,b   Weinshilboum, Richard M ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; HISTAMINE; HISTAMINE METHYLTRANSFERASE;

ALLELE; ANIMAL CELL; ARTICLE; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; FEMALE; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENOTYPE; HISTAMINE METABOLISM; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PHARMACOGENETICS; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031969375     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.53.4.708     Document Type: Article

References (40)

1. Aksoy S, Klener J, and Weinshilboum RM (1993) Catechol O-methyltransferase pharmacogenetics: photoaffinity labeling and western blot analysis of human liver samples. Pharmacogenetics 3:116-122.
2. Aksoy S, Raftogianis R, and Weinshilboum R (1996) Human histamine N-methyltransferase gene: structural characterization and chromosomal localization. Biochem Biophys Res Commun 219:548-554.
3. Boudíková B, Szumlanski C, Maidak B, and Weinshilboum R (1990) Human liver catechol O-methyltransferase pharmacogenetics. Clin Pharmacol Ther 48:381-389.
4. Boudíková-Girard B, Scott MC, and Weinshilboum R (1993) Histamine N-methyltransferase: inhibition by monoamine oxidase inhibitors. Agents Actions 40:1-10.
5. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
6. Brown DD, Tomchick R, and Axelrod J (1959) The distribution and properties of a histamine-methylating enzyme. J Biol Chem 234:2948-2950.
7. Burkard WP, Gey KF, and Pletscher A (1963) Diamine oxidase in the brain of vertebrates. J Neurochem 10:183-186.
8. Campbell NRC, Dunnette JH, Mwaluko G, Van Loon J, and Weinshilboum RM (1984) Platelet phenol sulfotransferase and erythrocyte catechol-O-methyltransferase activities: correlation with methyldopa metabolism in man. Clin Pharmacol Ther 35:55-63.
9. Cavalli-Sforza LL and Bodmer WF (1971) The Genetics of Human Populations. W. H. Freeman, San Francisco.
10. Chadwick RB, Conrad MP, McGinnis MD, Johnston-Dow L, Spurgeon SL, and Kronick MN (1996) Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase. Biotechniques 20:676-683.
11. Cleland WW (1963) Computer programmes for processing enzyme kinetic data. Nature (Lond) 198:463-465.
12. Dale HH and Laidlaw PP (1910) The physiological action of β-iminazolyethylamine. J Physiol 41:318-344.
13. Devereux J, Haeberli P, and Smithies O (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12:387-395.
14. Feinberg AP and Vogelstein B (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13.
15. Girard B, Otterness DM, Wood TC, Honchel R, Wieben ED, and Weinshilboum RM (1994) Human histamine N-methyltransferase pharmacogenetics: cloning and expression of kidney cDNA. Mol Pharmacol 45:461-468.
16. Ho SN, Hunt HD, Horton RM, Pullen JK, and Pease LR (1989) Site-directed mutagenesis by overlap extension using polymerase chain reaction. Gene 77:51-59.
17. Hough LB and Green JP (1984) Histamine and its receptors in the nervous system. Handb Neurochem 6:145-211.
18. Lachman HM, Papolos DF, Saito T, Yu Y-M, Szumlanski CL, and Weinshilboum RM (1996) Human catechol O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6:243-250.
19. Lennard L, Van Loon JA, Lilleyman JS, and Weinshilboum RM (1987) Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Pharmacol Ther 41:18-25.
20. Lennon G, Auffray C, Polymeropoulos M, and Soares MB (1996) The IMAGE Consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152.
21. Loiselle J and Wollin W (1993) Mucosal histamine elimination and its effect on acid secretion in rabbit gastric mucosa. Gastroenterology 104:1013-1020.
22. Luthman H and Magnusson G (1983) High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res 11:1295-1308.
23. Maslinski C (1975) Histamine and its metabolism in mammals. Part II. Catabolism of histamine and histamine liberation. Agents Actions 5:183-225.
24. Okinaga S, Ohrui T, Nakazawa H, Yamauchi K, Sakurai E, Watanabe T, Sekizawa K, and Sasaki H (1995) The role of HMT (histamine N-methyltransferase) in airways: a review. Methods Fundam Exp Clin Pharmacol 17(Suppl. C):16-20.
25. Pazmiño PA and Weinshilboum RM (1978) Human erythrocyte phenol-O-methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 89:317-329.
26. Price RA, Scott MC, and Weinshilboum RM (1993) Genetic segregation analysis of red blood cell (RBC) histamine N-methyltransferase (HNMT) activity. Genet Epidemiol 10:123-131.
27. Rosenthal N (1987) Identification of regulatory elements of cloned genes with functional assays. Methods Enzymol 152:704-720.
28. Scanlon PD, Raymond FA, and Weinshilboum RM (1979) Catechol-O-methyltransferase: thermolabile enzyme in erythrocytes of subjects homozygous for the allele for low activity. Science (Washington DC) 203:63-65.
29. Schwartz JC, Arrang MM, Garbarg M, Pollaed H, and Ruat M (1991) Histaminergic transmission in the mammalian brain. Physiol Rev 71:1-51.
30. Scott MC, Van Loon JA, and Weinshilboum RM (1988) Pharmacogenetics of N-methylation: heritability of human erythrocyte histamine N-methyltransferase activity. Clin Pharmacol Ther 43:256-262.
31. Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, Spurr N, Lennard L, Wieben E, and Weinshilboum R (1996) Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism. DNA Cell Biol 15:17-30.
32. Terwilliger JD and Ott J (1994) Handbook of Human Genetic Linkage. The Johns Hopkins University Press, Baltimore.
33. Towbin H, Staehelin T, and Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354.
34. Van Loon JA and Weinshilboum RM (1990) Thiopurine methyltransferase isozymes in human renal tissue. Drug Metab Dispos 18:632-638.
35. Van Loon JA, Pazmiño PA, and Weinshilboum RM (1985) Human erythrocyte histamine N-methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 149:237-251.
36. Wasserman SI (1983) Mediators of immediate hypersensitivity. J Allergy Clin Immunol 72:101-115.
37. Weinshilboum RM (1981) Enzyme thermal stability and population genetic studies: application to erythrocyte catechol-O-methyltransferase and plasma dopamine β-hydroxylase, in Genetic Strategies in Psychobiology and Psychiatry (Gershon ES, Matthysse S, Breakefield XO, and Ciaranello RD, eds), pp 79-94, Boxwood Press, Pacific Grove, CA.
38. Wilkinson GN (1961) Statistical estimations in enzyme kinetics. Biochem J 80:324-332.
39. Wood TC, Aksoy IA, Aksoy S, and Weinshilboum RM (1994) Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization. Biochem Biophys Res Commun 198:1119-1127.
40. Yamauchi K, Sekizawa K, Suzuki H, Nakazawa H, Ohkawara Y, Katayose D, Ohtsu H, Tamura G, Shibahara S, Takemura M, Maeyama K, Watanabe T, Sasaki H, Shirata K, and Takishima T (1994) Structure and function of human histamine N-methyltransferase: critical enzyme in histamine metabolism in airway. Am J Physiol 267:L342-L349.