Single nucleotide polymorphism in prohibitin 3′ untranslated region and breast-cancer susceptibility

Lancet

Volumn 357, Issue 9268, 2001, Pages 1588-1589

  Jupe, Eldon R ^a   Badgett, Allen A ^a   Neas, Barbara R ^b   Craft, Melissa A ^c   Mitchell, Debra S ^c   Resta, Regina ^b   Mulvihill, John J ^c   Aston, Christopher E ^a   Thompson, Linda F ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROHIBITIN PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ALLELE; ARTICLE; BREAST CARCINOMA; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA POLYMORPHISM; FAMILIAL CANCER; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK ASSESSMENT; UNTRANSLATED REGION;

EID: 0035912530     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)04747-4     Document Type: Article

References (5)

1. White J.J., Ledbetter D.H., Eddy R.L., et al. Assignment of the human prohibitin gene (PHB) to chromosome 17 and identification of a DNA polymorphism. Genomics. 11:1991;228-230.
2. Nagai M.A., Yamamoto L., Salaorni S., et al. Detailed deletion mapping of chromosome segment 17q12-21 in sporadic breast tumors. Genes Chromosomes Cancer. 11:1994;58-62.
3. Wang S., Nath N., Adlam M., Chellappan S. Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function. Oncogene. 18:1999;3501-3510.
4. Jupe E.R., Liu X.-T., Kiehlbauch J.L., et al. Prohibitin in breast cancer cell lines: loss of antiproliferative activity is linked to 39 untranslated region mutations. Cell Growth Differ. 7:1996;871-878.
5. Jupe E.R., Lerner M., Thompson L., et al. Prohibitin RNA therapy in a metastatic rat mammary tumor model. Proc AACR. 41:2000;353.