Further evidence for LBP-1c/CP2/LSF association in Alzheimer's disease families

Journal of Medical Genetics

Volumn 42, Issue 11, 2005, Pages 857-862

  Bertram, L ^a   Parkinson, M ^a   McQueen, M B ^b   Mullin, K ^a   Hsiao, M ^a   Menon, R ^a   Moscarillo, T J ^a   Blacker, D ^a   Tanzi, Rudolph E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPROTEIN RECEPTOR; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CHROMOSOME 12; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HUMAN; MALE; PATHOGENESIS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

3' UNTRANSLATED REGIONS; ALZHEIMER DISEASE; DNA-BINDING PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TRANSCRIPTION FACTORS;

EID: 27744498608     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.2004.024596     Document Type: Article

References (37)

1. Selkoe DJ. Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease. J Clin Invest 2002;110(10):1375- 81.
2. Tanzi RE, Bertram L. New frontiers in Alzheimer's disease genetics. Neuron 2001;32(2):181-4.
3. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993;90(5):1977-81.
4. Bertram L, Tanzi RE. Alzheimer's disease: one disorder, too many genes? Hum Mol Genet 2004;13(Spec No 1):R135-41.
5. Wu WS, Holmans P, Wavrant-DeVrieze F, Shears S, Kehoe P, Crook R, Booth J, Williams N, Perez-Tur J, Roehl K, Fenton I, Chartier-Harlin MC, Lovestone S, Williams J, Hutton M, Hardy J, Owen MJ, Goate A. Genetic studies on chromosome 12 in late-onset Alzheimer disease. JAMA 1998;280(7):619-22.
6. Mayeux R, Lee JH, Romas SN, Mayo D, Santana V, Williamson J, Ciappa A, Rondon HZ, Estevez P, Lantigua R, Medrano M, Torres M, Stern Y, Tycko B, Knowles JA. Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics. Am J Hum Genet 2002;70(1):237-43.
7. Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, Rice F, Giles P, Tunstall N, Jones L, Lovestone S, Williams J, Owen MJ, Hardy J, Goate A. Full genome screen for Alzheimer disease: stage II analysis. Am J Med Genet 2002;114(2):235-44.
8. Pericak-Vance MA, Bass MP, Yamaoka LH, Gaskell PC, Scott WK, Terwedow HA, Menold MM, Conneally PM, Small GW, Vance JM, Saunders AM, Roses AD, Haines JL. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. JAMA 1997;278(15):1237-41.
9. Rogaeva E, Premkumar S, Song Y, Sorbi S, Brindle N, Paterson A, Duara R, Levesque G, Yu G, Nishimura M, Ikeda M, O'Toole C, Kawarai T, Jorge R, Vilarino D, Bruni AC, Farrer LA, St George-Hyslop PH. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. JAMA 1998;280(7):614-8.
10. Bertram L, Tanzi RE. Dancing in the dark? The status of late-onset Alzheimer's disease genetics. J Mol Neurosci 2001;17(2):127-36.
11. Saunders AJ, Bertram L, Mullin K, Sampson AJ, Latifzai K, Basu S, Jones J, Kinney D, MacKenzie-Ingano L, Yu S, Albert MS, Moscarillo TJ, Go RC, Bassett SS, Daly MJ, Laird NM, Wang X, Velicelebi G, Wagner SL, Becker DK, Tanzi RE, Blacker D. Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Hum Mol Genet 2003;12(21):2765-76.
12. Lambert JC, Goumidi L, Vrieze FW, Frigard B, Harris JM, Cummings A, Coates J, Pasquier F, Cottel D, Gaillac M, St Clair D, Mann DM, Hardy J, Lendon CL, Amouyel P, Chartier-Harlin MC. The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease. Hum Mol Genet 2000;9(15):2275-80.
13. Taylor AE, Yip A, Brayne C, Easton D, Evans JG, Xuereb J, Cairns N, Esiri MM, Rubinsztein DC. Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. J Med Genet 2001;38(4):232-3.
14. Luedecking-Zimmer E, DeKosky ST, Nebes R, Kamboh MI. Association of the 3′ UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease. Am J Med Genet 2003;117B(1):114-7.
15. Panza F, D'Introno A, Colacicco AM, Capurso C, Basile AM, Torres F, Capurso A, Solfrizzi V. LBP-1c/CP2/LSF gene polymorphism and risk of sporadic Alzheimer's disease. J Neurol Neurosurg Psychiatry 2004;75(1):166-8.
16. Bing Z, Reddy SA, Ren Y, Qin J, Liao WS. Purification and characterization of the serum amyloid A3 enhancer factor. J Biol Chem 1999;274(35):24649-56.
17. Lau KF, Miller CC, Anderton BH, Shaw PC. Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter. Genomics 1999;60(2):121-8.
18. Zambrano N, Minopoli G, de Candia P, Russo T. The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1. J Biol Chem 1998;273(32):20128-33.
19. Cao X, Sudhof TC. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001;293(5527):115-20.
20. Blacker D, Albert MS, Bassett SS, Go RC, Harrell LE, Folstein MF. Reliability and validity of NINCDS-ADRDA criteria for Alzheimer's disease. The National Institute of Mental Health Genetics Initiative. Arch Neurol 1994;51(12):1198-204.
21. Blacker D, Bertram L, Saunders AJ, Moscarillo TJ, Albert MS, Wiener H, Perry RT, Collins JS, Harrell LE, Go RC, Mahoney A, Beaty T, Fallin MD, Avramopoulos D, Chase GA, Folstein MF, McInnis MG, Bassett SS, Doheny KJ, Pugh EW, Tanzi RE. Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet 2003;12(1):23-32.
22. Mullin K, Bertram L, Moscarillo TJ, Becker KD, Wang C, Growdon J, Blacker D, Tanzi RE. Genetic association within the IDE region on chromosome 10 - The Consortium on Alzheimer's Genetics (CAG). Poster (abstract no. 202.8) presented at the 33rd Annual Meeting of the Society for Neuroscience, New Orleans, LA, 2003.
23. Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered 2000;50(4):211-23.
24. Lake SL, Blacker D, Laird NM. Family-based tests of association in the presence of linkage. Am J Hum Genet 2000;67(6):1515-25.
25. Martin ER, Monks SA, Warren LL, Kaplan NL. A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet 2000;67(1):146-54.
26. Martin ER, Bass MP, Kaplan NL. Correcting for a potential bias in the pedigree disequilibrium test. Am J Hum Genet 2001;68(4):1065-7.
27. Witte JS, Gauderman WJ, Thomas DC. Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs. Am J Epidemiol 1999;149(8):693-705.
28. Siegmund KD, Langholz B, Kraft P, Thomas DC. Testing linkage disequilibrium in sibships. Am J Hum Genet 2000;67(1):244-8.
29. Laird NM, Mosteller F. Some statistical methods for combining experimental results. Int J Technol Assess Health Care 1990;6(1):5-30.
30. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7(3):177-88.
31. Ioannidis JP, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG. Replication validity of genetic association studies. Nat Genet 2001;29(3):306-9.
32. Sanchez-Guerra M, Combarros O, Infante J, Llorca J, Berciano J, Fontalba A, Fernandez-Luna JL, Pena N, Fernandez-Viadero C. Case-control study and meta-analysis of low density lipoprotein receptor-related protein gene exon 3 polymorphism in Alzheimer's disease. Neurosci Lett 2001;316(1):17-20.
33. Kolsch H, Ptok U, Mohamed I, Schmitz S, Rao ML, Maier W, Heun R. Association of the C766T polymorphism of the low-density lipoprotein receptor-related protein gene with Alzheimer's disease. Am J Med Genet 2003;121B(1):128-30.
34. Perry RT, Collins JS, Wiener H, Acton R, Go RC. The role of TNF and its receptors in Alzheimer's disease. Neurobiol Aging 2001;22(6):873-83.
35. Alvarez V, Mata IF, Gonzalez P, Lahoz CH, Martinez C, Pena J, Guisasola LM, Coto E. Association between the TNFalpha-308 A/G polymorphism and the onset-age of Alzheimer disease. Am J Med Genet 2002;114(5):574-7.
36. Lehmann DJ, Johnston C, Smith AD. Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease. Hum Mol Genet 1997;6(11):1933-6.
37. Hiltunen M, Mannermaa A, Helisalmi S, Koivisto A, Lehtovirta M, Ryynanen M, Riekkinen P Sr, Soininen H. Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients. Neurosci Lett 1998;250(1):69-71.