메뉴 건너뛰기




Volumn 70, Issue 5, 2006, Pages 854-864

Polycystic kidney disease: Cell division without a c(l)ue?

Author keywords

Cilium; Inversin; Oriented cell division; Planar cell polarity; Polycystic kidney disease; Wnt

Indexed keywords

BETA CATENIN; INVERSIN; POLYCYSTIN 1; POLYCYSTIN 2; PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 33747838464     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5001534     Document Type: Review
Times cited : (117)

References (111)
  • 1
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Wilson PD. Polycystic kidney disease. N Engl J Med 2004; 350: 151-164.
    • (2004) N Engl J Med , vol.350 , pp. 151-164
    • Wilson, P.D.1
  • 2
    • 0142106807 scopus 로고    scopus 로고
    • Role of polycystins in renal tubulogenesis
    • Boletta A, Germino GG. Role of polycystins in renal tubulogenesis. Trends Cell Biol 2003; 13: 484-492.
    • (2003) Trends Cell Biol , vol.13 , pp. 484-492
    • Boletta, A.1    Germino, G.G.2
  • 3
    • 0035083551 scopus 로고    scopus 로고
    • The genetics and physiology of polycystic kidney disease
    • Calvet JP, Grantham JJ. The genetics and physiology of polycystic kidney disease. Semin Nephrol 2001; 21: 107-123.
    • (2001) Semin Nephrol , vol.21 , pp. 107-123
    • Calvet, J.P.1    Grantham, J.J.2
  • 4
    • 3242728834 scopus 로고    scopus 로고
    • Polycystins: From mechanosensation to gene regulation
    • Delmas P. Polycystins: from mechanosensation to gene regulation. Cell 2004; 118: 145-148.
    • (2004) Cell , vol.118 , pp. 145-148
    • Delmas, P.1
  • 5
    • 20144375842 scopus 로고    scopus 로고
    • Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin
    • Otto EA, Loeys B, Khanna H et al. Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet 2005; 37: 282-288.
    • (2005) Nat Genet , vol.37 , pp. 282-288
    • Otto, E.A.1    Loeys, B.2    Khanna, H.3
  • 6
    • 2942534582 scopus 로고    scopus 로고
    • Polycystic kidney disease: New understanding in the pathogenesis
    • Wilson PD. Polycystic kidney disease: new understanding in the pathogenesis. Int J Biochem Cell Biol 2004; 36: 1868-1873.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1868-1873
    • Wilson, P.D.1
  • 7
    • 31744443557 scopus 로고    scopus 로고
    • Ciliary proteins and exencephaly
    • Katsanis N. Ciliary proteins and exencephaly. Nat Genet 2006; 38: 135-136.
    • (2006) Nat Genet , vol.38 , pp. 135-136
    • Katsanis, N.1
  • 8
    • 0041592700 scopus 로고    scopus 로고
    • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
    • Otto EA, Schermer B, Obara T et al. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet 2003; 34: 413-420.
    • (2003) Nat Genet , vol.34 , pp. 413-420
    • Otto, E.A.1    Schermer, B.2    Obara, T.3
  • 9
    • 0033848676 scopus 로고    scopus 로고
    • Molecular genetics of nephronophthisis and medullary cystic kidney disease
    • In Process Citation
    • Hildebrandt F, Otto E. Molecular genetics of nephronophthisis and medullary cystic kidney disease [In Process Citation]. J Am Soc Nephrol 2000; 11: 1753-1761.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1753-1761
    • Hildebrandt, F.1    Otto, E.2
  • 10
    • 0029016742 scopus 로고
    • Proliferative activity of cyst epithelium in human renal cystic diseases
    • Nadasdy T, Laszik Z, Lajoie G et al. Proliferative activity of cyst epithelium in human renal cystic diseases. J Am Soc Nephrol 1995; 5: 1462-1468.
    • (1995) J Am Soc Nephrol , vol.5 , pp. 1462-1468
    • Nadasdy, T.1    Laszik, Z.2    Lajoie, G.3
  • 11
    • 0029805189 scopus 로고    scopus 로고
    • Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD)
    • Lanoix J, D'Agati V, Szabolcs M et al. Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD). Oncogene 1996; 13: 1153-1160.
    • (1996) Oncogene , vol.13 , pp. 1153-1160
    • Lanoix, J.1    D'Agati, V.2    Szabolcs, M.3
  • 12
    • 0027221060 scopus 로고
    • Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney disease
    • Wilson PD, Du J, Norman JT. Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney disease. Eur J Cell Biol 1993; 61: 131-138.
    • (1993) Eur J Cell Biol , vol.61 , pp. 131-138
    • Wilson, P.D.1    Du, J.2    Norman, J.T.3
  • 13
    • 0029082997 scopus 로고
    • Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD
    • Du J, Wilson PD. Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD. Am J Physiol 1995; 269: C487-C495.
    • (1995) Am J Physiol , vol.269
    • Du, J.1    Wilson, P.D.2
  • 14
    • 0025755515 scopus 로고
    • Reversed polarity of Na(+) -K(+) -ATPase: Mislocation to apical plasma membranes in polycystic kidney disease epithelia
    • Wilson PD, Sherwood AC, Palla K et al. Reversed polarity of Na(+) -K(+) -ATPase: mislocation to apical plasma membranes in polycystic kidney disease epithelia. Am J Physiol 1991; 260: F420-F430.
    • (1991) Am J Physiol , vol.260
    • Wilson, P.D.1    Sherwood, A.C.2    Palla, K.3
  • 15
    • 2642645109 scopus 로고
    • Abnormalities in polarized molecular transport in PKD cyst epithelia
    • Wilson P, Falkenstein D, Gatti L et al. Abnormalities in polarized molecular transport in PKD cyst epithelia. Kidney Int 1995; 47: 724-725.
    • (1995) Kidney Int , vol.47 , pp. 724-725
    • Wilson, P.1    Falkenstein, D.2    Gatti, L.3
  • 16
    • 0032513031 scopus 로고    scopus 로고
    • The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1
    • Arnould T, Kim E, Tsiokas L et al. The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1. J Biol Chem 1998; 273: 6013-6018.
    • (1998) J Biol Chem , vol.273 , pp. 6013-6018
    • Arnould, T.1    Kim, E.2    Tsiokas, L.3
  • 17
    • 0032552866 scopus 로고    scopus 로고
    • The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro
    • Parnell SC, Magenheimer BS, Maser RL et al. The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro. Biochem Biophys Res Commun 1998; 251: 625-631.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 625-631
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3
  • 18
    • 0037205429 scopus 로고    scopus 로고
    • Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins
    • Parnell SC, Magenheimer BS, Maser RL et al. Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins. J Biol Chem 2002; 277: 19566-19572.
    • (2002) J Biol Chem , vol.277 , pp. 19566-19572
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3
  • 19
    • 85047694216 scopus 로고    scopus 로고
    • Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus
    • Chauvet V, Tian X, Husson H et al. Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus. J Clin Invest 2004; 114: 1433-1443.
    • (2004) J Clin Invest , vol.114 , pp. 1433-1443
    • Chauvet, V.1    Tian, X.2    Husson, H.3
  • 20
    • 0036175934 scopus 로고    scopus 로고
    • The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells
    • Nickel C, Benzing T, Sellin L et al. The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells. J Clin Invest 2002; 109: 481-489.
    • (2002) J Clin Invest , vol.109 , pp. 481-489
    • Nickel, C.1    Benzing, T.2    Sellin, L.3
  • 21
    • 0037133954 scopus 로고    scopus 로고
    • PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
    • Bhunia AK, Piontek K, Boletta A et al. PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 2002; 109: 157-168.
    • (2002) Cell , vol.109 , pp. 157-168
    • Bhunia, A.K.1    Piontek, K.2    Boletta, A.3
  • 22
    • 16844375093 scopus 로고    scopus 로고
    • Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation
    • Nishio S, Hatano M, Nagata M et al. Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest 2005; 115: 910-918.
    • (2005) J Clin Invest , vol.115 , pp. 910-918
    • Nishio, S.1    Hatano, M.2    Nagata, M.3
  • 23
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR et al. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993; 75: 229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3
  • 24
    • 0029035757 scopus 로고
    • Apoptosis and loss of renal tissue in polycystic kidney diseases
    • Woo D. Apoptosis and loss of renal tissue in polycystic kidney diseases. New Eng J Med 1995; 333: 18-25.
    • (1995) New Eng J Med , vol.333 , pp. 18-25
    • Woo, D.1
  • 25
    • 11244297916 scopus 로고    scopus 로고
    • Dysregulation of the TSC-mTOR pathway in human disease
    • Inoki K, Corradetti MN, Guan KL. Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 2005; 37: 19-24.
    • (2005) Nat Genet , vol.37 , pp. 19-24
    • Inoki, K.1    Corradetti, M.N.2    Guan, K.L.3
  • 26
    • 18744380752 scopus 로고    scopus 로고
    • Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease
    • Tao Y, Kim J, Schrier RW et al. Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease. J Am Soc Nephrol 2005; 16: 46-51.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 46-51
    • Tao, Y.1    Kim, J.2    Schrier, R.W.3
  • 27
    • 33644859253 scopus 로고    scopus 로고
    • Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD)
    • Wahl PR, Serra AL, Le Hir M et al. Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Nephrol Dial Transplant 2006; 21: 598-604.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 598-604
    • Wahl, P.R.1    Serra, A.L.2    Le Hir, M.3
  • 28
    • 0037108151 scopus 로고    scopus 로고
    • Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
    • Radimerski T, Montagne J, Hemmings-Mieszczak M et al. Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev 2002; 16: 2627-2632.
    • (2002) Genes Dev , vol.16 , pp. 2627-2632
    • Radimerski, T.1    Montagne, J.2    Hemmings-Mieszczak, M.3
  • 29
    • 0036714127 scopus 로고    scopus 로고
    • Akt regulates growth by directly phosphorylating Tsc2
    • Potter CJ, Pedraza LG, Xu T. Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol 2002; 4: 658-665.
    • (2002) Nat Cell Biol , vol.4 , pp. 658-665
    • Potter, C.J.1    Pedraza, L.G.2    Xu, T.3
  • 30
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling
    • Inoki K, Li Y, Zhu T et al. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling. Nat Cell Biol 2002; 4: 648-657.
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3
  • 31
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning BD, Tee AR, Logsdon MN et al. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell 2002; 10: 151-162.
    • (2002) Mol Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3
  • 32
    • 27944469172 scopus 로고    scopus 로고
    • An incredible decade for the primary cilium: A look at a once-forgotten organelle
    • Davenport JR, Yoder BK. An incredible decade for the primary cilium: a look at a once-forgotten organelle. Am J Physiol Renal Physiol 2005; 289: F1159-F1169.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Davenport, J.R.1    Yoder, B.K.2
  • 33
    • 16244368607 scopus 로고    scopus 로고
    • Intraflagellar transport and cilia-dependent renal disease: The ciliary hypothesis of polycystic kidney disease
    • Pazour GJ. Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease. J Am Soc Nephrol 2004; 15: 2528-2536.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2528-2536
    • Pazour, G.J.1
  • 34
    • 0029383640 scopus 로고
    • Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease
    • Yoder BK, Richards WG, Sweeney WE et al. Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease. Proc Assoc Am Physicians 1995; 107: 314-323.
    • (1995) Proc Assoc Am Physicians , vol.107 , pp. 314-323
    • Yoder, B.K.1    Richards, W.G.2    Sweeney, W.E.3
  • 35
    • 0034042763 scopus 로고    scopus 로고
    • The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination
    • Murcia NS, Richards WG, Yoder BK et al. The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development 2000; 127: 2347-2355.
    • (2000) Development , vol.127 , pp. 2347-2355
    • Murcia, N.S.1    Richards, W.G.2    Yoder, B.K.3
  • 36
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y et al. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 1998; 95: 829-837.
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3
  • 37
    • 19044374304 scopus 로고    scopus 로고
    • Intraflagellar transport
    • Rosenbaum J. Intraflagellar transport. Curr Biol 2002; 12: R125.
    • (2002) Curr Biol , vol.12
    • Rosenbaum, J.1
  • 38
    • 0345255945 scopus 로고    scopus 로고
    • Intraflagellar transport
    • Scholey JM. Intraflagellar transport. Annu Rev Cell Dev Biol 2003; 19: 423-443.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 423-443
    • Scholey, J.M.1
  • 39
    • 0034735526 scopus 로고    scopus 로고
    • Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
    • Pazour GJ, Dickert BL, Vucica Y et al. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 2000; 151: 709-718.
    • (2000) J Cell Biol , vol.151 , pp. 709-718
    • Pazour, G.J.1    Dickert, B.L.2    Vucica, Y.3
  • 40
    • 0035916823 scopus 로고    scopus 로고
    • An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons
    • Qin H, Rosenbaum JL, Barr MM. An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons. Curr Biol 2001; 11: 457-461.
    • (2001) Curr Biol , vol.11 , pp. 457-461
    • Qin, H.1    Rosenbaum, J.L.2    Barr, M.M.3
  • 41
    • 0034987372 scopus 로고    scopus 로고
    • The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms
    • Haycraft CJ, Swoboda P, Taulman PD et al. The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms. Development 2001; 128: 1493-1505.
    • (2001) Development , vol.128 , pp. 1493-1505
    • Haycraft, C.J.1    Swoboda, P.2    Taulman, P.D.3
  • 42
    • 0035806961 scopus 로고    scopus 로고
    • The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway
    • Barr MM, DeModena J, Braun D et al. The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway. Curr Biol 2001; 11: 1341-1346.
    • (2001) Curr Biol , vol.11 , pp. 1341-1346
    • Barr, M.M.1    DeModena, J.2    Braun, D.3
  • 43
    • 0033598394 scopus 로고    scopus 로고
    • A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
    • Barr MM, Sternberg PW. A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans [see comments]. Nature 1999; 401: 386-389.
    • (1999) Nature , vol.401 , pp. 386-389
    • Barr, M.M.1    Sternberg, P.W.2
  • 44
    • 0028895406 scopus 로고
    • Sensory regulation of male mating behavior in Caenorhabditis elegans
    • Liu KS, Sternberg PW. Sensory regulation of male mating behavior in Caenorhabditis elegans. Neuron 1995; 14: 79-89.
    • (1995) Neuron , vol.14 , pp. 79-89
    • Liu, K.S.1    Sternberg, P.W.2
  • 45
    • 0036785149 scopus 로고    scopus 로고
    • The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
    • Yoder BK, Hou X, Guay-Woodford LM. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 2002; 13: 2508-2516.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2508-2516
    • Yoder, B.K.1    Hou, X.2    Guay-Woodford, L.M.3
  • 46
    • 28844460656 scopus 로고    scopus 로고
    • Cilia and centrosomes: A unifying pathogenic concept for cystic kidney disease?
    • Hildebrandt F, Otto E. Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease? Nat Rev Genet 2005; 6: 928-940.
    • (2005) Nat Rev Genet , vol.6 , pp. 928-940
    • Hildebrandt, F.1    Otto, E.2
  • 47
    • 4544383179 scopus 로고    scopus 로고
    • A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
    • Sun Z, Amsterdam A, Pazour GJ et al. A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development 2004; 131: 4085-4093.
    • (2004) Development , vol.131 , pp. 4085-4093
    • Sun, Z.1    Amsterdam, A.2    Pazour, G.J.3
  • 48
    • 0037884961 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
    • Lin F, Hiesberger T, Cordes K et al. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 2003; 100: 5286-5291.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5286-5291
    • Lin, F.1    Hiesberger, T.2    Cordes, K.3
  • 49
    • 0037317302 scopus 로고    scopus 로고
    • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
    • Nauli SM, Alenghat FJ, Luo Y et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 2003; 33: 129-137.
    • (2003) Nat Genet , vol.33 , pp. 129-137
    • Nauli, S.M.1    Alenghat, F.J.2    Luo, Y.3
  • 50
    • 18844393668 scopus 로고    scopus 로고
    • Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
    • Kramer-Zucker AG, Olale F, Haycraft CJ et al. Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development 2005; 132: 1907-1921.
    • (2005) Development , vol.132 , pp. 1907-1921
    • Kramer-Zucker, A.G.1    Olale, F.2    Haycraft, C.J.3
  • 51
    • 0015075027 scopus 로고
    • Cilia in the fetal kidney of man
    • Zimmermann HD. [Cilia in the fetal kidney of man]. Beitr Pathol 1971; 143: 227-240.
    • (1971) Beitr Pathol , vol.143 , pp. 227-240
    • Zimmermann, H.D.1
  • 53
    • 27144529532 scopus 로고    scopus 로고
    • PDGFR alpha signaling is regulated through the primary cilium in fibroblasts
    • Schneider L, Clement CA, Teilmann SC et al. PDGFR alpha signaling is regulated through the primary cilium in fibroblasts. Curr Biol 2005; 15: 1861-1866.
    • (2005) Curr Biol , vol.15 , pp. 1861-1866
    • Schneider, L.1    Clement, C.A.2    Teilmann, S.C.3
  • 54
    • 26644460824 scopus 로고    scopus 로고
    • Vertebrate smoothened functions at the primary cilium
    • Corbit KC, Aanstad P, Singla V et al. Vertebrate smoothened functions at the primary cilium. Nature 2005; 437: 1018-1021.
    • (2005) Nature , vol.437 , pp. 1018-1021
    • Corbit, K.C.1    Aanstad, P.2    Singla, V.3
  • 55
    • 40749144679 scopus 로고    scopus 로고
    • Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
    • Haycraft CJ, Banizs B, Aydin-Son Y et al. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 2005; 1: e53.
    • (2005) PLoS Genet , vol.1
    • Haycraft, C.J.1    Banizs, B.2    Aydin-Son, Y.3
  • 56
    • 22344445826 scopus 로고    scopus 로고
    • Cilia and the cell cycle?
    • Quarmby LM, Parker JD. Cilia and the cell cycle? J Cell Biol 2005; 169: 707-710.
    • (2005) J Cell Biol , vol.169 , pp. 707-710
    • Quarmby, L.M.1    Parker, J.D.2
  • 58
    • 0028826392 scopus 로고
    • Loss of spatial control of the mitotic spindle apparatus in a Chlamydomonas reinhardtii mutant strain lacking basal bodies
    • Ehler LL, Holmes JA, Dutcher SK. Loss of spatial control of the mitotic spindle apparatus in a Chlamydomonas reinhardtii mutant strain lacking basal bodies. Genetics 1995; 141: 945-960.
    • (1995) Genetics , vol.141 , pp. 945-960
    • Ehler, L.L.1    Holmes, J.A.2    Dutcher, S.K.3
  • 59
    • 0024811663 scopus 로고
    • The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium
    • Bacallao R, Antony C, Dotti C et al. The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium. J Cell Biol 1989; 109: 2817-2832.
    • (1989) J Cell Biol , vol.109 , pp. 2817-2832
    • Bacallao, R.1    Antony, C.2    Dotti, C.3
  • 60
    • 0346874342 scopus 로고    scopus 로고
    • Proteomic characterization of the human centrosome by protein correlation profiling
    • Andersen JS, Wilkinson CJ, Mayor T et al. Proteomic characterization of the human centrosome by protein correlation profiling. Nature 2003; 426: 570-574.
    • (2003) Nature , vol.426 , pp. 570-574
    • Andersen, J.S.1    Wilkinson, C.J.2    Mayor, T.3
  • 61
    • 0033525007 scopus 로고    scopus 로고
    • Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts
    • Hinchcliffe EH, Li C, Thompson EA et al. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. Science 1999; 283: 851-854.
    • (1999) Science , vol.283 , pp. 851-854
    • Hinchcliffe, E.H.1    Li, C.2    Thompson, E.A.3
  • 62
    • 0033055061 scopus 로고    scopus 로고
    • Cyclin-dependent kinase control of centrosome duplication
    • Lacey KR, Jackson PK, Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proc Natl Acad Sci USA 1999; 96: 2817-2822.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2817-2822
    • Lacey, K.R.1    Jackson, P.K.2    Stearns, T.3
  • 63
    • 6344241294 scopus 로고    scopus 로고
    • A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells
    • Mahjoub MR, Qasim Rasi M, Quarmby LM. A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells. Mol Biol Cell 2004; 15: 5172-5186.
    • (2004) Mol Biol Cell , vol.15 , pp. 5172-5186
    • Mahjoub, M.R.1    Qasim Rasi, M.2    Quarmby, L.M.3
  • 64
    • 1842431397 scopus 로고    scopus 로고
    • Cellular deflagellation
    • Quarmby LM. Cellular deflagellation. Int Rev Cytol 2004; 233: 47-91.
    • (2004) Int Rev Cytol , vol.233 , pp. 47-91
    • Quarmby, L.M.1
  • 65
    • 0034602780 scopus 로고    scopus 로고
    • Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice
    • Upadhya P, Birkenmeier EH, Birkenmeier CS et al. Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice. Proc Natl Acad Sci USA 2000; 97: 217-221.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 217-221
    • Upadhya, P.1    Birkenmeier, E.H.2    Birkenmeier, C.S.3
  • 66
    • 0036931712 scopus 로고    scopus 로고
    • A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish
    • Liu S, Lu W, Obara T et al. A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. Development 2002; 129: 5839-5846.
    • (2002) Development , vol.129 , pp. 5839-5846
    • Liu, S.1    Lu, W.2    Obara, T.3
  • 67
    • 33645904854 scopus 로고    scopus 로고
    • NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes
    • Mahjoub MR, Trapp ML, Quarmby LM. NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes. J Am Soc Nephrol 2005; 16: 3485-3489.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3485-3489
    • Mahjoub, M.R.1    Trapp, M.L.2    Quarmby, L.M.3
  • 68
    • 0037115494 scopus 로고    scopus 로고
    • Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
    • Morgan D, Eley L, Sayer J et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Genet 2002; 11: 3345-3350.
    • (2002) Hum Mol Genet , vol.11 , pp. 3345-3350
    • Morgan, D.1    Eley, L.2    Sayer, J.3
  • 69
    • 3042626108 scopus 로고    scopus 로고
    • The Invs gene encodes a microtubule-associated protein
    • Nurnberger J, Kribben A, Opazo Saez A et al. The Invs gene encodes a microtubule-associated protein. J Am Soc Nephrol 2004; 15: 1700-1710.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1700-1710
    • Nurnberger, J.1    Kribben, A.2    Opazo Saez, A.3
  • 70
    • 0036732917 scopus 로고    scopus 로고
    • Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells
    • Nurnberger J, Bacallao RL, Phillips CL. Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells. Mol Biol Cell 2002; 13: 3096-3106.
    • (2002) Mol Biol Cell , vol.13 , pp. 3096-3106
    • Nurnberger, J.1    Bacallao, R.L.2    Phillips, C.L.3
  • 71
    • 0037009056 scopus 로고    scopus 로고
    • Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells
    • Kallio MJ, Beardmore VA, Weinstein J et al. Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. J Cell Biol 2002; 158: 841-847.
    • (2002) J Cell Biol , vol.158 , pp. 841-847
    • Kallio, M.J.1    Beardmore, V.A.2    Weinstein, J.3
  • 72
    • 0037166933 scopus 로고    scopus 로고
    • The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time
    • Raff JW, Jeffers K, Huang JY. The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time. J Cell Biol 2002; 157: 1139-1149.
    • (2002) J Cell Biol , vol.157 , pp. 1139-1149
    • Raff, J.W.1    Jeffers, K.2    Huang, J.Y.3
  • 73
    • 0037126610 scopus 로고    scopus 로고
    • APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box
    • Hames RS, Wattam SL, Yamano H et al. APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box. EMBO J 2001; 20: 7117-7127.
    • (2001) EMBO J , vol.20 , pp. 7117-7127
    • Hames, R.S.1    Wattam, S.L.2    Yamano, H.3
  • 74
    • 0142104970 scopus 로고    scopus 로고
    • Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome
    • Ansley SJ, Badano JL, Blacque OE et al. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 2003; 425: 628-633.
    • (2003) Nature , vol.425 , pp. 628-633
    • Ansley, S.J.1    Badano, J.L.2    Blacque, O.E.3
  • 75
    • 0028588919 scopus 로고
    • Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
    • Stark K, Vainio S, Vassileva G et al. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 1994; 372: 679-683.
    • (1994) Nature , vol.372 , pp. 679-683
    • Stark, K.1    Vainio, S.2    Vassileva, G.3
  • 76
    • 22944463010 scopus 로고    scopus 로고
    • Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system
    • Carroll TJ, Park JS, Hayashi S et al. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 2005; 9: 283-292.
    • (2005) Dev Cell , vol.9 , pp. 283-292
    • Carroll, T.J.1    Park, J.S.2    Hayashi, S.3
  • 77
    • 0043172526 scopus 로고    scopus 로고
    • Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development
    • Majumdar A, Vainio S, Kispert A et al. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 2003; 130: 3175-3185.
    • (2003) Development , vol.130 , pp. 3175-3185
    • Majumdar, A.1    Vainio, S.2    Kispert, A.3
  • 78
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004; 303: 1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 79
    • 0035921733 scopus 로고    scopus 로고
    • Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene
    • Saadi-Kheddouci S, Berrebi D, Romagnolo B et al. Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene. Oncogene 2001; 20: 5972-5981.
    • (2001) Oncogene , vol.20 , pp. 5972-5981
    • Saadi-Kheddouci, S.1    Berrebi, D.2    Romagnolo, B.3
  • 80
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons M, Gloy J, Ganner A et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005; 37: 537-543.
    • (2005) Nat Genet , vol.37 , pp. 537-543
    • Simons, M.1    Gloy, J.2    Ganner, A.3
  • 81
    • 0037102507 scopus 로고    scopus 로고
    • The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
    • Schwarz-Romond T, Asbrand C, Bakkers J et al. The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev 2002; 16: 2073-2084.
    • (2002) Genes Dev , vol.16 , pp. 2073-2084
    • Schwarz-Romond, T.1    Asbrand, C.2    Bakkers, J.3
  • 82
    • 0037452932 scopus 로고    scopus 로고
    • Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors
    • Maretto S, Cordenonsi M, Dupont S et al. Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci USA 2003; 100: 3299-3304.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3299-3304
    • Maretto, S.1    Cordenonsi, M.2    Dupont, S.3
  • 83
    • 18144415886 scopus 로고
    • Studies on fetal urine secretion
    • Friedberg V. [Studies on fetal urine secretion. Gynaecologia 1955; 140: 34-45.
    • (1955) Gynaecologia , vol.140 , pp. 34-45
    • Friedberg, V.1
  • 84
    • 27744538492 scopus 로고    scopus 로고
    • Planar cell polarization: An emerging model points in the right direction
    • Klein TJ, Mlodzik M. Planar cell polarization: an emerging model points in the right direction. Annu Rev Cell Dev Biol 2004; 21: 155-176.
    • (2004) Annu Rev Cell Dev Biol , vol.21 , pp. 155-176
    • Klein, T.J.1    Mlodzik, M.2
  • 85
    • 18144431330 scopus 로고    scopus 로고
    • Linking cilia to Wnts
    • Germino GG. Linking cilia to Wnts. Nat Genet 2005; 37: 455-457.
    • (2005) Nat Genet , vol.37 , pp. 455-457
    • Germino, G.G.1
  • 86
    • 0037013168 scopus 로고    scopus 로고
    • Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling
    • Tree DR, Shulman JM, Rousset R et al. Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 2002; 109: 371-381.
    • (2002) Cell , vol.109 , pp. 371-381
    • Tree, D.R.1    Shulman, J.M.2    Rousset, R.3
  • 87
    • 31744436549 scopus 로고    scopus 로고
    • Polarized transport of frizzled along the planar microtubule arrays in drosophila wing epithelium
    • Shimada Y, Yonemura S, Ohkura H et al. Polarized transport of frizzled along the planar microtubule arrays in drosophila wing epithelium. Dev Cell 2006; 10: 209-222.
    • (2006) Dev Cell , vol.10 , pp. 209-222
    • Shimada, Y.1    Yonemura, S.2    Ohkura, H.3
  • 88
    • 33644624937 scopus 로고    scopus 로고
    • Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
    • Park TJ, Haigo SL, Wallingford JB. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet 2006; 38: 303-311.
    • (2006) Nat Genet , vol.38 , pp. 303-311
    • Park, T.J.1    Haigo, S.L.2    Wallingford, J.B.3
  • 89
    • 0035929273 scopus 로고    scopus 로고
    • Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder
    • Katsanis N, Ansley SJ, Badano JL et al. Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder. Science 2001; 293: 2256-2259.
    • (2001) Science , vol.293 , pp. 2256-2259
    • Katsanis, N.1    Ansley, S.J.2    Badano, J.L.3
  • 90
    • 19444377129 scopus 로고    scopus 로고
    • Lifting the lid on Pandora's box: The Bardet-Biedl syndrome
    • Beales PL. Lifting the lid on Pandora's box: the Bardet-Biedl syndrome. Curr Opin Genet Dev 2005; 15: 315-323.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 315-323
    • Beales, P.L.1
  • 91
    • 2342501364 scopus 로고    scopus 로고
    • Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene
    • Li JB, Gerdes JM, Haycraft CJ et al. Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. Cell 2004; 117: 541-552.
    • (2004) Cell , vol.117 , pp. 541-552
    • Li, J.B.1    Gerdes, J.M.2    Haycraft, C.J.3
  • 92
    • 2342657884 scopus 로고    scopus 로고
    • Decoding cilia function: Defining specialized genes required for compartmentalized cilia biogenesis
    • Avidor-Reiss T, Maer AM, Koundakjian E et al. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Cell 2004; 117: 527-539.
    • (2004) Cell , vol.117 , pp. 527-539
    • Avidor-Reiss, T.1    Maer, A.M.2    Koundakjian, E.3
  • 93
    • 20244381625 scopus 로고    scopus 로고
    • The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
    • Kim JC, Badano JL, Sibold S et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat Genet 2004; 36: 462-470.
    • (2004) Nat Genet , vol.36 , pp. 462-470
    • Kim, J.C.1    Badano, J.L.2    Sibold, S.3
  • 94
    • 27144460671 scopus 로고    scopus 로고
    • Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    • Ross AJ, May-Simera H, Eichers ER et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet 2005; 37.
    • (2005) Nat Genet , vol.37
    • Ross, A.J.1    May-Simera, H.2    Eichers, E.R.3
  • 95
    • 13844292417 scopus 로고    scopus 로고
    • Antenatal presentation of Bardet-Biedl syndrome may mimic Meckel syndrome
    • Karmous-Benailly H, Martinovic J, Gubler MC et al. Antenatal presentation of Bardet-Biedl syndrome may mimic Meckel syndrome. Am J Hum Genet 2005; 76: 493-504.
    • (2005) Am J Hum Genet , vol.76 , pp. 493-504
    • Karmous-Benailly, H.1    Martinovic, J.2    Gubler, M.C.3
  • 96
    • 31744435454 scopus 로고    scopus 로고
    • MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome
    • Kyttala M, Tallila J, Salonen R et al. MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome. Nat Genet 2006; 38: 155-157.
    • (2006) Nat Genet , vol.38 , pp. 155-157
    • Kyttala, M.1    Tallila, J.2    Salonen, R.3
  • 97
    • 31744441248 scopus 로고    scopus 로고
    • The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat
    • Smith UM, Consugar M, Tee LJ et al. The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat. Nat Genet 2006; 38: 191-196.
    • (2006) Nat Genet , vol.38 , pp. 191-196
    • Smith, U.M.1    Consugar, M.2    Tee, L.J.3
  • 98
    • 23644449576 scopus 로고    scopus 로고
    • Centrosome localization determines neuronal polarity
    • de Anda FC, Pollarolo G, Da Silva JS et al. Centrosome localization determines neuronal polarity. Nature 2005; 436: 704-708.
    • (2005) Nature , vol.436 , pp. 704-708
    • De Anda, F.C.1    Pollarolo, G.2    Da Silva, J.S.3
  • 99
    • 0035478337 scopus 로고    scopus 로고
    • The centrosome in vertebrates: More than a microtubule-organizing center
    • Rieder CL, Faruki S, Khodjakov A. The centrosome in vertebrates: more than a microtubule-organizing center. Trends Cell Biol 2001; 11: 413-419.
    • (2001) Trends Cell Biol , vol.11 , pp. 413-419
    • Rieder, C.L.1    Faruki, S.2    Khodjakov, A.3
  • 100
    • 4544318596 scopus 로고    scopus 로고
    • Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos
    • Cowan CR, Hyman AA. Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos. Nature 2004; 431: 92-96.
    • (2004) Nature , vol.431 , pp. 92-96
    • Cowan, C.R.1    Hyman, A.A.2
  • 101
    • 4344659154 scopus 로고    scopus 로고
    • Polarity proteins control ciliogenesis via kinesin motor interactions
    • Fan S, Hurd TW, Liu CJ et al. Polarity proteins control ciliogenesis via kinesin motor interactions. Curr Biol 2004; 14: 1451-1461.
    • (2004) Curr Biol , vol.14 , pp. 1451-1461
    • Fan, S.1    Hurd, T.W.2    Liu, C.J.3
  • 102
    • 24944575221 scopus 로고    scopus 로고
    • The orientation of cell divisions determines the shape of Drosophila organs
    • Baena-Lopez LA, Baonza A, Garcia-Bellido A. The orientation of cell divisions determines the shape of Drosophila organs. Curr Biol 2005; 15: 1640-1644.
    • (2005) Curr Biol , vol.15 , pp. 1640-1644
    • Baena-Lopez, L.A.1    Baonza, A.2    Garcia-Bellido, A.3
  • 103
    • 0032516178 scopus 로고    scopus 로고
    • Frizzled signaling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila
    • Gho M, Schweisguth F. Frizzled signaling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 1998; 393: 178-181.
    • (1998) Nature , vol.393 , pp. 178-181
    • Gho, M.1    Schweisguth, F.2
  • 104
    • 3943102141 scopus 로고    scopus 로고
    • Planar cell polarity signaling controls cell division orientation during zebrafish gastrulation
    • Gong Y, Mo C, Fraser SE. Planar cell polarity signaling controls cell division orientation during zebrafish gastrulation. Nature 2004; 430: 689-693.
    • (2004) Nature , vol.430 , pp. 689-693
    • Gong, Y.1    Mo, C.2    Fraser, S.E.3
  • 105
    • 30544439006 scopus 로고    scopus 로고
    • Planar cell polarity signaling couples cell division and morphogenesis during neurulation
    • Ciruna B, Jenny A, Lee D et al. Planar cell polarity signaling couples cell division and morphogenesis during neurulation. Nature 2006; 439: 220-224.
    • (2006) Nature , vol.439 , pp. 220-224
    • Ciruna, B.1    Jenny, A.2    Lee, D.3
  • 106
    • 29444450890 scopus 로고    scopus 로고
    • Defective planar cell polarity in polycystic kidney disease
    • Fischer E, Legue E, Doyen A et al. Defective planar cell polarity in polycystic kidney disease. Nat Genet 2006; 38: 21-23.
    • (2006) Nat Genet , vol.38 , pp. 21-23
    • Fischer, E.1    Legue, E.2    Doyen, A.3
  • 107
    • 2142659368 scopus 로고    scopus 로고
    • Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice
    • Hiesberger T, Bai Y, Shao X et al. Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice. J Clin Invest 2004; 113: 814-825.
    • (2004) J Clin Invest , vol.113 , pp. 814-825
    • Hiesberger, T.1    Bai, Y.2    Shao, X.3
  • 108
    • 2342508500 scopus 로고    scopus 로고
    • A transcriptional network in polycystic kidney disease
    • Gresh L, Fischer E, Reimann A et al. A transcriptional network in polycystic kidney disease. EMBO J 2004; 23: 1657-1668.
    • (2004) EMBO J , vol.23 , pp. 1657-1668
    • Gresh, L.1    Fischer, E.2    Reimann, A.3
  • 109
    • 0035945614 scopus 로고    scopus 로고
    • Adherens junctions inhibit asymmetric division in the Drosophila epithelium
    • Lu B, Roegiers F, Jan LY et al. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 2001; 409: 522-525.
    • (2001) Nature , vol.409 , pp. 522-525
    • Lu, B.1    Roegiers, F.2    Jan, L.Y.3
  • 110
    • 0032744937 scopus 로고    scopus 로고
    • Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins
    • Huan Y, van Adelsberg J. Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins. J Clin Invest 1999; 104: 1459-1468.
    • (1999) J Clin Invest , vol.104 , pp. 1459-1468
    • Huan, Y.1    Van Adelsberg, J.2
  • 111
    • 27144495462 scopus 로고    scopus 로고
    • The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
    • Pugacheva EN, Golemis EA. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol 2005; 7: 937-946.
    • (2005) Nat Cell Biol , vol.7 , pp. 937-946
    • Pugacheva, E.N.1    Golemis, E.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.