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Volumn 38, Issue 3, 2006, Pages 303-311

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GENE PRODUCT; PROTEIN XFY; PROTEIN XINT; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

EID: 33644624937     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1753     Document Type: Article
Times cited : (313)

References (50)
  • 1
    • 17844394941 scopus 로고    scopus 로고
    • Neural tube closure and neural tube defects: Studies in animal models reveal known knowns and known unknowns
    • Wallingford, J.B. Neural tube closure and neural tube defects: Studies in animal models reveal known knowns and known unknowns. Am. J. Med. Genet. C Semin. Med. Genet. 135, 59-68 (2005).
    • (2005) Am. J. Med. Genet. C Semin. Med. Genet. , vol.135 , pp. 59-68
    • Wallingford, J.B.1
  • 2
    • 0036843202 scopus 로고    scopus 로고
    • Planar cell polarization: Do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?
    • Mlodzik, M. Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet. 18, 564-571 (2002).
    • (2002) Trends Genet. , vol.18 , pp. 564-571
    • Mlodzik, M.1
  • 3
    • 0035479989 scopus 로고    scopus 로고
    • Frizzled signaling and cell-cell interactions in planar polarity
    • Adler, P.N. & Lee, H. Frizzled signaling and cell-cell interactions in planar polarity. Curr. Opin. Cell Biol. 13, 635-640 (2001).
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 635-640
    • Adler, P.N.1    Lee, H.2
  • 4
    • 0035408009 scopus 로고    scopus 로고
    • The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization
    • Feiguin, F., Hannus, M., Mlodzik, M. & Eaton, S. The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Dev. Cell 1, 93-101 (2001).
    • (2001) Dev. Cell , vol.1 , pp. 93-101
    • Feiguin, F.1    Hannus, M.2    Mlodzik, M.3    Eaton, S.4
  • 5
    • 22144446755 scopus 로고    scopus 로고
    • Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding
    • Jenny, A., Reynolds-Kenneally, J., Das, G., Burnett, M. & Mlodzik, M. Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nat. Cell Biol. 7, 691-697 (2005).
    • (2005) Nat. Cell Biol. , vol.7 , pp. 691-697
    • Jenny, A.1    Reynolds-Kenneally, J.2    Das, G.3    Burnett, M.4    Mlodzik, M.5
  • 6
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons, M. et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat. Genet. 37, 537-543 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 537-543
    • Simons, M.1
  • 7
    • 0037959910 scopus 로고    scopus 로고
    • The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia
    • Watanabe, D. et al. The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia. Development 130, 1725-1734 (2003).
    • (2003) Development , vol.130 , pp. 1725-1734
    • Watanabe, D.1
  • 8
    • 27144460671 scopus 로고    scopus 로고
    • Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    • Ross, A.J. et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 37, 1135-1140 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 1135-1140
    • Ross, A.J.1
  • 9
    • 26644460824 scopus 로고    scopus 로고
    • Vertebrate Smoothened functions at the primary cilium
    • Corbit, K.C. et al. Vertebrate Smoothened functions at the primary cilium. Nature 437, 1018-1021 (2005).
    • (2005) Nature , vol.437 , pp. 1018-1021
    • Corbit, K.C.1
  • 10
    • 0242581681 scopus 로고    scopus 로고
    • Hedgehog signalling in the mouse requires intraflagellar transport proteins
    • Huangfu, D. et al. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426, 83-87 (2003).
    • (2003) Nature , vol.426 , pp. 83-87
    • Huangfu, D.1
  • 11
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu, A., Wang, B. & Niswander, L.A. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132, 3103-3111 (2005).
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.1    Wang, B.2    Niswander, L.A.3
  • 12
    • 23844485210 scopus 로고    scopus 로고
    • Cilia and Hedgehog responsiveness in the mouse
    • Huangfu, D. & Anderson, K.V. Cilia and Hedgehog responsiveness in the mouse. Proc. Natl. Acad. Sci. USA 102, 11325-11330 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 11325-11330
    • Huangfu, D.1    Anderson, K.V.2
  • 13
    • 10744227509 scopus 로고    scopus 로고
    • Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse
    • Curtin, J.A. et al. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr. Biol. 13, 1129-1133 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 1129-1133
    • Curtin, J.A.1
  • 14
    • 0141480791 scopus 로고    scopus 로고
    • Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm
    • Han, Y.G., Kwok, B.H. & Kernan, M.J. Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Curr. Biol. 13, 1679-1686 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 1679-1686
    • Han, Y.G.1    Kwok, B.H.2    Kernan, M.J.3
  • 15
    • 0030776197 scopus 로고    scopus 로고
    • Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein
    • Collier, S. & Gubb, D. Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein. Development 124, 4029-4037 (1997).
    • (1997) Development , vol.124 , pp. 4029-4037
    • Collier, S.1    Gubb, D.2
  • 16
    • 0029918895 scopus 로고    scopus 로고
    • The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein
    • Park, W.J., Liu, J., Sharp, E.J. & Adler, P.N. The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein. Development 122, 961-969 (1996).
    • (1996) Development , vol.122 , pp. 961-969
    • Park, W.J.1    Liu, J.2    Sharp, E.J.3    Adler, P.N.4
  • 17
    • 0036239198 scopus 로고    scopus 로고
    • The function of the frizzled pathway in the Drosophila wing is dependent on inturned and fuzzy
    • Lee, H. & Adler, P.N. The function of the frizzled pathway in the Drosophila wing is dependent on inturned and fuzzy. Genetics 160, 1535-1547 (2002).
    • (2002) Genetics , vol.160 , pp. 1535-1547
    • Lee, H.1    Adler, P.N.2
  • 18
    • 0034904642 scopus 로고    scopus 로고
    • Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown
    • Draper, B.W., Morcos, P.A. & Kimmel, C.B. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30, 154-156 (2001).
    • (2001) Genesis , vol.30 , pp. 154-156
    • Draper, B.W.1    Morcos, P.A.2    Kimmel, C.B.3
  • 19
    • 0032749014 scopus 로고    scopus 로고
    • The role of sonic hedgehog in normal and abnormal craniofacial morphogenesis
    • Hu, D. & Helms, J.A. The role of sonic hedgehog in normal and abnormal craniofacial morphogenesis. Development 126, 4873-4884 (1999).
    • (1999) Development , vol.126 , pp. 4873-4884
    • Hu, D.1    Helms, J.A.2
  • 20
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
    • Chiang, C. et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413 (1996).
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1
  • 21
    • 0029024046 scopus 로고
    • Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis
    • Ekker, S.C. et al. Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis. Development 121, 2337-2347 (1995).
    • (1995) Development , vol.121 , pp. 2337-2347
    • Ekker, S.C.1
  • 22
    • 0033386715 scopus 로고    scopus 로고
    • Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system
    • Hallonet, M., Hollemann, T., Pieler, T. & Gruss, P. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev. 13, 3106-3114 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 3106-3114
    • Hallonet, M.1    Hollemann, T.2    Pieler, T.3    Gruss, P.4
  • 23
    • 26244466207 scopus 로고    scopus 로고
    • Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull
    • Wada, N. et al. Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull. Development 132, 3977-3988 (2005).
    • (2005) Development , vol.132 , pp. 3977-3988
    • Wada, N.1
  • 24
    • 1942466507 scopus 로고    scopus 로고
    • Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia
    • Jeong, J., Mao, J., Tenzen, T., Kottmann, A.H. & McMahon, A.P. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 18, 937-951 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 937-951
    • Jeong, J.1    Mao, J.2    Tenzen, T.3    Kottmann, A.H.4    McMahon, A.P.5
  • 25
    • 0026939392 scopus 로고
    • Skeletal development in Xenopus laevis (Anura: Pipidae)
    • Trueb, L. & Hanken, J. Skeletal development in Xenopus laevis (Anura: Pipidae). J. Morphol. 214, 1-41 (1992).
    • (1992) J. Morphol. , vol.214 , pp. 1-41
    • Trueb, L.1    Hanken, J.2
  • 26
    • 18344414777 scopus 로고    scopus 로고
    • Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus
    • Lopez, S.L. et al. Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus. Development 130, 2225-2238 (2003).
    • (2003) Development , vol.130 , pp. 2225-2238
    • Lopez, S.L.1
  • 27
    • 12244273274 scopus 로고    scopus 로고
    • XHRT-1, a hairy and Enhancer of split related gene with expression in floor plate and hypochord during early Xenopus embryogenesis
    • Pichon, B., Taelman, V., Kricha, S., Christophe, D. & Bellefroid, E.J. XHRT-1, a hairy and Enhancer of split related gene with expression in floor plate and hypochord during early Xenopus embryogenesis. Dev. Genes Evol. 212, 491-495 (2002).
    • (2002) Dev. Genes Evol. , vol.212 , pp. 491-495
    • Pichon, B.1    Taelman, V.2    Kricha, S.3    Christophe, D.4    Bellefroid, E.J.5
  • 28
    • 0037348570 scopus 로고    scopus 로고
    • Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity
    • Take-uchi, M., Clarke, J.D. & Wilson, S.W. Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 130, 955-968 (2003).
    • (2003) Development , vol.130 , pp. 955-968
    • Take-uchi, M.1    Clarke, J.D.2    Wilson, S.W.3
  • 29
    • 0034915909 scopus 로고    scopus 로고
    • Xenopus dishevelled signaling regulates both neural and mesodermal convergent extension: Parallel forces elongating the body axis
    • Wallingford, J.B. & Harland, R.M. Xenopus dishevelled signaling regulates both neural and mesodermal convergent extension: parallel forces elongating the body axis. Development 128, 2581-2592 (2001).
    • (2001) Development , vol.128 , pp. 2581-2592
    • Wallingford, J.B.1    Harland, R.M.2
  • 30
    • 0036922915 scopus 로고    scopus 로고
    • Neural tube closure requires Dishevelled-dependent convergent extension of the midline
    • Wallingford, J.B. & Harland, R.M. Neural tube closure requires Dishevelled-dependent convergent extension of the midline. Development 129, 5815-5825 (2002).
    • (2002) Development , vol.129 , pp. 5815-5825
    • Wallingford, J.B.1    Harland, R.M.2
  • 31
    • 0026586983 scopus 로고
    • The cellular basis of the convergence and extension of the Xenopus neural plate
    • Keller, R., Shih, J. & Safer, A. The cellular basis of the convergence and extension of the Xenopus neural plate. Dev. Dyn. 193, 199-217 (1992).
    • (1992) Dev. Dyn. , vol.193 , pp. 199-217
    • Keller, R.1    Shih, J.2    Safer, A.3
  • 32
    • 0034729910 scopus 로고    scopus 로고
    • Mechanisms of convergence and extension by cell intercalation
    • Keller, R. et al. Mechanisms of convergence and extension by cell intercalation. Phil. Trans. R. Soc. Lond. B 355, 897-922 (2000).
    • (2000) Phil. Trans. R. Soc. Lond. B , vol.355 , pp. 897-922
    • Keller, R.1
  • 33
    • 0032533299 scopus 로고    scopus 로고
    • The shaping of pharyngeal cartilages during early development of the zebrafish
    • Kimmel, C.B. et al. The shaping of pharyngeal cartilages during early development of the zebrafish. Dev. Biol. 203, 245-263 (1998).
    • (1998) Dev. Biol. , vol.203 , pp. 245-263
    • Kimmel, C.B.1
  • 34
    • 0035434453 scopus 로고    scopus 로고
    • The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
    • Topczewski, J. et al. The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev. Cell 1, 251-264 (2001).
    • (2001) Dev. Cell , vol.1 , pp. 251-264
    • Topczewski, J.1
  • 35
    • 0027076099 scopus 로고
    • Fate of ciliated epidermal cells during early development of Xenopus laevis using whole-mount immunostaining with an antibody against chondroitin 6-sulfate proteoglycan and anti-tubulin: Transdifferentiation or metaplasia of amphibian epidermis
    • Nishikawa, S., Hirata, J. & Sasaki, F. Fate of ciliated epidermal cells during early development of Xenopus laevis using whole-mount immunostaining with an antibody against chondroitin 6-sulfate proteoglycan and anti-tubulin: transdifferentiation or metaplasia of amphibian epidermis. Histochemistry 98, 355-358 (1992).
    • (1992) Histochemistry , vol.98 , pp. 355-358
    • Nishikawa, S.1    Hirata, J.2    Sasaki, F.3
  • 36
    • 0343385028 scopus 로고
    • Notes on the ciliation of the ectoderm of the amphibian embryo
    • Assheton, R. Notes on the ciliation of the ectoderm of the amphibian embryo. Q. J. Microsc. Sci. 38, 465-484 (1896).
    • (1896) Q. J. Microsc. Sci. , vol.38 , pp. 465-484
    • Assheton, R.1
  • 37
    • 20244381625 scopus 로고    scopus 로고
    • The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
    • Kim, J.C. et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat. Genet. 36, 462-470 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 462-470
    • Kim, J.C.1
  • 38
    • 4444254983 scopus 로고    scopus 로고
    • Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
    • Kulaga, H.M. et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat. Genet. 36, 994-998 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 994-998
    • Kulaga, H.M.1
  • 39
    • 0024463570 scopus 로고
    • Organization of actin microfilaments in the apical border of oviduct ciliated cells
    • Chailley, B., Nicolas, G. & Laine, M.C. Organization of actin microfilaments in the apical border of oviduct ciliated cells. Biol. Cell. 67, 81-90 (1989).
    • (1989) Biol. Cell. , vol.67 , pp. 81-90
    • Chailley, B.1    Nicolas, G.2    Laine, M.C.3
  • 40
    • 0025129057 scopus 로고
    • Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium
    • Boisvieux-Ulrich, E., Laine, M.C. & Sandoz, D. Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium. Cell Tissue Res. 259, 443-454 (1990).
    • (1990) Cell Tissue Res. , vol.259 , pp. 443-454
    • Boisvieux-Ulrich, E.1    Laine, M.C.2    Sandoz, D.3
  • 41
    • 0025993792 scopus 로고
    • Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct
    • Boisvieux-Ulrich, E. & Sandoz, D. Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct. Biol. Cell. 72, 3-14 (1991).
    • (1991) Biol. Cell. , vol.72 , pp. 3-14
    • Boisvieux-Ulrich, E.1    Sandoz, D.2
  • 42
    • 0023711583 scopus 로고
    • Development of macrociliary cells in Beroë
    • Tamm, S. & Tamm, S.L. Development of macrociliary cells in Beroë. J. Cell Sci. 89, 67-80 (1988).
    • (1988) J. Cell Sci. , vol.89 , pp. 67-80
    • Tamm, S.1    Tamm, S.L.2
  • 43
    • 9244243685 scopus 로고    scopus 로고
    • Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins
    • Adler, P.N., Zhu, C. & Stone, D. Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins. Curr. Biol. 14, 2046-2051 (2004).
    • (2004) Curr. Biol. , vol.14 , pp. 2046-2051
    • Adler, P.N.1    Zhu, C.2    Stone, D.3
  • 44
    • 1942502194 scopus 로고    scopus 로고
    • Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium
    • Hagiwara, H., Ohwada, N. & Takata, K. Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium. Int. Rev. Cytol. 234, 101-141 (2004).
    • (2004) Int. Rev. Cytol. , vol.234 , pp. 101-141
    • Hagiwara, H.1    Ohwada, N.2    Takata, K.3
  • 45
    • 0030458493 scopus 로고    scopus 로고
    • Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila
    • Eaton, S., Wepf, R. & Simons, K. Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. J. Cell Biol. 135, 1277-1289 (1996).
    • (1996) J. Cell Biol. , vol.135 , pp. 1277-1289
    • Eaton, S.1    Wepf, R.2    Simons, K.3
  • 46
    • 0035888642 scopus 로고    scopus 로고
    • Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification
    • Murdoch, J.N., Doudney, K., Paternotte, C., Copp, A.J. & Stanier, P. Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum. Mol. Genet. 10, 2593-2601 (2001).
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2593-2601
    • Murdoch, J.N.1    Doudney, K.2    Paternotte, C.3    Copp, A.J.4    Stanier, P.5
  • 47
    • 0027138170 scopus 로고
    • Planar polarity in the ciliated epidermis of Xenopus embryos
    • Konig, G. & Hausen, P. Planar polarity in the ciliated epidermis of Xenopus embryos. Dev. Biol. 160, 355-368 (1993).
    • (1993) Dev. Biol. , vol.160 , pp. 355-368
    • Konig, G.1    Hausen, P.2
  • 48
    • 18844393668 scopus 로고    scopus 로고
    • Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
    • Kramer-Zucker, A.G. et al. Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development 132, 1907-1921 (2005).
    • (2005) Development , vol.132 , pp. 1907-1921
    • Kramer-Zucker, A.G.1
  • 49
    • 0041592700 scopus 로고    scopus 로고
    • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
    • Otto, E.A. et al. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat. Genet. 34, 413-420 (2003).
    • (2003) Nat. Genet. , vol.34 , pp. 413-420
    • Otto, E.A.1
  • 50
    • 17144377111 scopus 로고    scopus 로고
    • Cilium-generated signaling and cilia-related disorders
    • Pan, J., Wang, Q. & Snell, W.J. Cilium-generated signaling and cilia-related disorders. Lab. Invest. 85, 452-463 (2005).
    • (2005) Lab. Invest. , vol.85 , pp. 452-463
    • Pan, J.1    Wang, Q.2    Snell, W.J.3


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