A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

Nature

Volumn 401, Issue 6751, 1999, Pages 386-389

  Barr, Maureen M ^a   Sternberg, Paul W ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCYSTIN;

ARTICLE; CAENORHABDITIS ELEGANS; GENETIC ANALYSIS; KIDNEY POLYCYSTIC DISEASE; MATING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SENSORY SYSTEM; VULVA;

CAENORHABDITIS ELEGANS; INVERTEBRATA; NEMATODA;

EID: 0033598394     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/43913     Document Type: Article

References (30)

1. Hodgius, J. in The Nematode C. elegans (ed. Wood, B.) 243-279 (Cold Spring Harbor Laboratory Press, New York, 1988).
2. Liu, K. S. & Sternberg, P. W. Sensory regulation of male mating behavior in Caenorhabditis elegans. Neuron 14, 79-89 (1995).
3. Carraaway, K. L. & Fregien, N. Macin structure and function: Insights from molecular biology. Trends Glycosci. Glycotechnol. 7, 31-44 (1993).
4. Torres, V. D. New insights into polycystic kidney disease and its treatment. Curr. Opin. Nephrol. Hypertess. 7, 159-169 (1988).
5. Ward, S., Thomson, N., White, J. G. & Brenner, S. Electron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans. J. Comp. Neurol. 160, 313-337 (1975).
6. White, J. G., Southgate, D., Thomson, J. N. & Brenner, S. The structure of the nervous system of Caenorhabditis elegans. Phil. Trans. R. Soc. Lond. B 314, 1-340 (1986).
7. Collet, J., Spike, C. A., Lundquist, E. A., Shaw, J. E. & Herman, R. K. Analysis of osm-6, a gene that affects sensory cilium structure and sensory neuron function in Caenorhabditis elegans. Genetics 148, 187-200 (1998).
8. Kaplan, J. M. & Horvitz, H. R. A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 90, 2227-2231 (1993).
9. Perkins, L. A., Hedgecock, E. M., Thomson, J. N. & Culotti, J. G. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev. Biol. 117, 456-487 (1986).
10. Mochizuki, T. et al. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 242, 1339-1342 (1996).
11. Montell, C. & Rubin, G. M. Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2, 1313-1323 (1989).
12. Sanford, R. et al. Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. Hum. Mol. Genet. 9, 1483-1489 (1997).
13. Nomura, H. et al. Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal detects. J. Biol. Chem. 273, 25967-25973 (1998).
14. Wu, G. et al. Identification of PKD2L, a human PKD2-related gene: Tissue-specific expression and mapping to chromosome 10q25. Genomics 54, 564-568 (1998).
15. Qian, F. et al. PKD1 interacts with PKD2 through a probably coiled-coil domain. Nature Genet. 16, 179-183 (1997).
16. Tsiokas, L., Kim, E., Arnould, T., Sukhatme, V. P. & Walz, G. Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. Proc. Natl Acad. Sci. USA 94, 6965-6970 (1997).
17. Arnould, T. et al. The polycystic kidney disease 1 gene product mediates protein kinase C α-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1. J. Biol. Chem. 273, 6013-6018 (1998).
18. Parnell, S. C. et al. The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro. Biochem. Biophys. Res. Commun. 251, 625-631 (1998).
19. Kim, E. et al. The polycystic kidney kidney disease 1 gene product modulates Wnt signaling. J. Biol. Chem. 274, 4947-4953 (1999).
20. Tsiokas, L. et al. Specific association of the gene product of PKD2 with the TRPC1 channel. Proc. Natl Acad. Sci. USA 7, 3934-3939 (1999).
21. Sullivan, L. P., Wallace, D. P. & Grantham, J. J. Epithelial transport in polycystic kidney disease. Physiol. Rev. 78, 1165-1191 (1998).
22. Hudspeth, A. J. How the ear's works work. Nature 341, 397-404 (1989).
23. Driscoll, M. & Kaplan, J. in C. elegans II (ed. Riddle, D. I., Blumenthal, T., Meyer, B. J. & Priess, J. R.) 645-677 (Cold spring Harbor Laboratory Press, New York, 1997).
24. Montell, C. TRP trapped in the fly signalling web. Curr. Opin. Neurobiol. 8, 389-397 (1998).
25. Brenner, S. The genetics of Caenorhabditis elegans. Genetics 77, 71-94 (1974).
26. Hodgkin, J. Male phenotypes and mating efficiency in Caenorhaditis elegans. Genetics 103, 43-64 (1983).
27. Hodgkin, J. & Doniach, T. Natural variation and copulatory plug formation in Caenorhabditis elegans. Genetics 146, 149-164 (1997).
28. Schnabel, H. & Schnabel, R. An organ-specific differentiation gene, pha-1, from Caenorhabditis elegans. Science 250, 686-688 (1990),
29. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W. & Prasher, D. D. Green fluorescent protein as a marker for gene expression. Science 263, 802-805 (1994).
30. Sulston, J. D., Albertson, D. G. & Thomson, J. N. The Caenorhabditis elegans male: Postembryonic development of nongonadal structures. Dev. Biol. 78, 542-576 (1980).