-
1
-
-
0028825940
-
Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle
-
Al-Ani, B., M. Saifeddine, and M. D. Hollenberg. Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can. J. Physiol. Pharmacol. 73: 1203-1207, 1995.
-
(1995)
Can. J. Physiol. Pharmacol.
, vol.73
, pp. 1203-1207
-
-
Al-Ani, B.1
Saifeddine, M.2
Hollenberg, M.D.3
-
2
-
-
0028027901
-
Analogues of the thrombin receptor tethered-ligand enhance mesangial cell proliferation
-
Albrightson, C. R., B. Zabko-Potapovich, G. Dytko, W. M. Bryan, K. Hoyle, M. L. Moore, and J. M. Stadel. Analogues of the thrombin receptor tethered-ligand enhance mesangial cell proliferation. Cell. Signal. 6: 743-750, 1994.
-
(1994)
Cell. Signal.
, vol.6
, pp. 743-750
-
-
Albrightson, C.R.1
Zabko-Potapovich, B.2
Dytko, G.3
Bryan, W.M.4
Hoyle, K.5
Moore, M.L.6
Stadel, J.M.7
-
3
-
-
0027517590
-
Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle
-
Antonaccio, M. J., D. Normandin, R. Serafino, and S. Moreland. Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle. J. Pharmacol. Exp. Ther. 266: 125-132, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 125-132
-
-
Antonaccio, M.J.1
Normandin, D.2
Serafino, R.3
Moreland, S.4
-
4
-
-
0028979999
-
G12 requirement for thrombin-stimulated gene expression and DNA synthesis in 1321N1 astrocytoma cells
-
Aragay, A. M., L. R. Collins, G. R. Post, A. J. Watson, J. R. Feramisco, J. H. Brown, and M. I. Simon. G12 requirement for thrombin-stimulated gene expression and DNA synthesis in 1321N1 astrocytoma cells. J. Biol. Chem. 270: 20073-20077, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20073-20077
-
-
Aragay, A.M.1
Collins, L.R.2
Post, G.R.3
Watson, A.J.4
Feramisco, J.R.5
Brown, J.H.6
Simon, M.I.7
-
5
-
-
0029818156
-
Rat uterine stromal cells: Thrombin receptor and growth stimulation by thrombin
-
Arena, C. S., S. M. Quirk, Y. Q. Zhang, and K. P. Henrikson. Rat uterine stromal cells: thrombin receptor and growth stimulation by thrombin. Endocrinology 137: 3744-3749, 1996.
-
(1996)
Endocrinology
, vol.137
, pp. 3744-3749
-
-
Arena, C.S.1
Quirk, S.M.2
Zhang, Y.Q.3
Henrikson, K.P.4
-
7
-
-
0028237885
-
G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts
-
Baffy, G., L. Yang, S. Raj, D. R. Manning, and J. R. Williamson. G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts. J. Biol. Chem. 269: 8483-8487, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8483-8487
-
-
Baffy, G.1
Yang, L.2
Raj, S.3
Manning, D.R.4
Williamson, J.R.5
-
8
-
-
0026816214
-
Thrombin as a multifunctional protein: Induction of cell adhesion and proliferation
-
Bar-Shavit, R., M. Benezra, V. Sabbah, W. Bode, and I. Vlodavsky. Thrombin as a multifunctional protein: induction of cell adhesion and proliferation. Am. J. Respir. Cell Mol. Biol. 6: 123-130, 1992.
-
(1992)
Am. J. Respir. Cell Mol. Biol.
, vol.6
, pp. 123-130
-
-
Bar-Shavit, R.1
Benezra, M.2
Sabbah, V.3
Bode, W.4
Vlodavsky, I.5
-
9
-
-
0028085095
-
Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture
-
Beecher, K. L., T. T. Andersen, J. W. Fenton II, and B. W. Festoff. Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture. J. Neurosci. Res. 37: 108-115, 1994.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 108-115
-
-
Beecher, K.L.1
Andersen, T.T.2
Fenton II, J.W.3
Festoff, B.W.4
-
10
-
-
0030470167
-
Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases
-
Belham, C. M., R. J. Tate, P. H. Scott, A. D. Pemberton, H. R. Miller, R. M. Wadsworth, G. W. Gould, and R. Plevin. Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochem. J. 320: 939-946, 1996.
-
(1996)
Biochem. J.
, vol.320
, pp. 939-946
-
-
Belham, C.M.1
Tate, R.J.2
Scott, P.H.3
Pemberton, A.D.4
Miller, H.R.5
Wadsworth, R.M.6
Gould, G.W.7
Plevin, R.8
-
11
-
-
0028923464
-
q family
-
q family. FEBS Lett. 363: 49-52, 1995.
-
(1995)
FEBS Lett.
, vol.363
, pp. 49-52
-
-
Benka, M.L.1
Lee, M.2
Wang, G.-R.3
Buckman, S.4
Burlacu, A.5
Cole, L.6
Depina, A.7
Dias, P.8
Granger, A.9
Grant, B.10
-
12
-
-
0029758276
-
Development of potent thrombin receptor antagonist peptides
-
Bernatowicz, M. S., C. E. Klimas, K. S. Hartl, M. Peluso, N. J. Allegretto, and S. M. Seiler. Development of potent thrombin receptor antagonist peptides. J. Med. Chem. 39: 4879-4887, 1996.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4879-4887
-
-
Bernatowicz, M.S.1
Klimas, C.E.2
Hartl, K.S.3
Peluso, M.4
Allegretto, N.J.5
Seiler, S.M.6
-
13
-
-
0029952336
-
Ligand cross-reactivity within the protease-activated receptor family
-
Blackhart, B. D., K Emilsson, D. Nguyen, W. Teng, A. J. Martelli, S. Nystedt, J. Sundelin, and R. M. Scarborough. Ligand cross-reactivity within the protease-activated receptor family. J. Biol. Chem. 271: 16466-16471, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16466-16471
-
-
Blackhart, B.D.1
Emilsson, K.2
Nguyen, D.3
Teng, W.4
Martelli, A.J.5
Nystedt, S.6
Sundelin, J.7
Scarborough, R.M.8
-
14
-
-
0027233448
-
Signal transduction via the MAP kinases: Proceed at your own RSK
-
Blenis, J. Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. USA 90: 5889-5892, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5889-5892
-
-
Blenis, J.1
-
15
-
-
0031059468
-
Mechanisms attenuating signaling by G-protein coupled receptors
-
Böhm, S., E. F. Grady, and N. W. Bunnett. Mechanisms attenuating signaling by G-protein coupled receptors. Biochem. J. 322: 1-18, 1997.
-
(1997)
Biochem. J.
, vol.322
, pp. 1-18
-
-
Böhm, S.1
Grady, E.F.2
Bunnett, N.W.3
-
16
-
-
0029786481
-
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2
-
Böhm, S. K., L. M. Khitin, E. F. Grady, G. Aponte, D. G. Payan, and N. W. Bunnett. Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J. Biol. Chem. 271: 22003-22016, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22003-22016
-
-
Böhm, S.K.1
Khitin, L.M.2
Grady, E.F.3
Aponte, G.4
Payan, D.G.5
Bunnett, N.W.6
-
17
-
-
0029929603
-
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2
-
Böhm, S. K., W. Kong, D. Brömme, S. P. Smeekens, D. C. Anderson, A. Connolly, M. Kahn, N. A. Nelken, S. R. Coughlin, D. G. Payan, and N. W. Bunnett. Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem. J. 314: 1009-1016, 1996.
-
(1996)
Biochem. J.
, vol.314
, pp. 1009-1016
-
-
Böhm, S.K.1
Kong, W.2
Brömme, D.3
Smeekens, S.P.4
Anderson, D.C.5
Connolly, A.6
Kahn, M.7
Nelken, N.A.8
Coughlin, S.R.9
Payan, D.G.10
Bunnett, N.W.11
-
18
-
-
0028797819
-
Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system
-
Bouton, M. C., M. Jandrot-Perrus, S. Moog, J. P. Cazenave, M. C. Guillin, and F. Lanza. Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system. Biochem. J. 305: 635-641, 1995.
-
(1995)
Biochem. J.
, vol.305
, pp. 635-641
-
-
Bouton, M.C.1
Jandrot-Perrus, M.2
Moog, S.3
Cazenave, J.P.4
Guillin, M.C.5
Lanza, F.6
-
19
-
-
0030069077
-
The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: Presence of a disulfide bond
-
Boyd, N. D., R. Kage, J. J. Dumas, J. E. Krause, and S. E. Leeman. The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: presence of a disulfide bond. Proc. Natl. Acad. Sci. USA 93: 433-437, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 433-437
-
-
Boyd, N.D.1
Kage, R.2
Dumas, J.J.3
Krause, J.E.4
Leeman, S.E.5
-
20
-
-
0030841124
-
Protease-activated G protein-coupled receptors on human platelets and endothelial cells
-
Brass, L. F., and M. Molino. Protease-activated G protein-coupled receptors on human platelets and endothelial cells. Thromb. Haemost. 78: 234-241, 1997.
-
(1997)
Thromb. Haemost.
, vol.78
, pp. 234-241
-
-
Brass, L.F.1
Molino, M.2
-
21
-
-
0028111114
-
Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling
-
Brass, L. F., S. Pizarro, M. Ahuja, E. Belmonte, N. Blanchard, J. M. Stadel, and J. A. Hoxie. Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling. J. Biol. Chem. 269: 2943-2952, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2943-2952
-
-
Brass, L.F.1
Pizarro, S.2
Ahuja, M.3
Belmonte, E.4
Blanchard, N.5
Stadel, J.M.6
Hoxie, J.A.7
-
22
-
-
0028937714
-
Tryptase-induced mitogenesis in airway smooth muscle cells. Potency, mechanisms, and interactions with other mast cell mediators
-
Brown, J. K., C. A. Jones, C. L. Tyler, S. J. Ruoss, T. Hartmann, and G. H. Caughey. Tryptase-induced mitogenesis in airway smooth muscle cells. Potency, mechanisms, and interactions with other mast cell mediators. Chest 107: 95S-96S, 1995.
-
(1995)
Chest
, vol.107
-
-
Brown, J.K.1
Jones, C.A.2
Tyler, C.L.3
Ruoss, S.J.4
Hartmann, T.5
Caughey, G.H.6
-
23
-
-
0000666315
-
Tryptase, the dominant secretory granular protein in human mast cells, is a potent mitogen for cultured dog tracheal smooth muscle cells
-
Brown, J. K., C. L. Tyler, C. A. Jones, S. J. Ruoss, T. Hartmann, and G. H. Caughey. Tryptase, the dominant secretory granular protein in human mast cells, is a potent mitogen for cultured dog tracheal smooth muscle cells. J. Clin. Invest. 88: 493-499, 1991.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 493-499
-
-
Brown, J.K.1
Tyler, C.L.2
Jones, C.A.3
Ruoss, S.J.4
Hartmann, T.5
Caughey, G.H.6
-
24
-
-
0030032558
-
Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intracellular adhesion molecule-1 expression
-
Cairns, J. A., and A. F. Walls. Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intracellular adhesion molecule-1 expression. J. Immunol. 156: 275-283, 1995.
-
(1995)
J. Immunol.
, vol.156
, pp. 275-283
-
-
Cairns, J.A.1
Walls, A.F.2
-
25
-
-
0025255579
-
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1
-
Cavanaugh, K. P., D. Gurwitz, D. D. Cunningham, and R. A. Bradshaw. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J. Neurochem. 54: 1735-1743, 1990.
-
(1990)
J. Neurochem.
, vol.54
, pp. 1735-1743
-
-
Cavanaugh, K.P.1
Gurwitz, D.2
Cunningham, D.D.3
Bradshaw, R.A.4
-
26
-
-
0027938974
-
Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
-
Chen, H. C., and J. L. Guan. Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 91: 10148-10152, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10148-10152
-
-
Chen, H.C.1
Guan, J.L.2
-
27
-
-
0028364862
-
Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode
-
Chen, J., M. Ishii, L. Wang, K. Ishii, and S. R. Coughlin. Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode. J. Biol. Chem. 269: 16041-16045, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16041-16045
-
-
Chen, J.1
Ishii, M.2
Wang, L.3
Ishii, K.4
Coughlin, S.R.5
-
28
-
-
0029915662
-
Functional expression of a human thrombin receptor in Sf9 insect cells: Evidence for an active tethered ligand
-
Chen, X., K. Barley, W. Luo, S. H. Lin, and W. P. Schilling. Functional expression of a human thrombin receptor in Sf9 insect cells: evidence for an active tethered ligand. Biochem. J. 314: 603-611, 1996.
-
(1996)
Biochem. J.
, vol.314
, pp. 603-611
-
-
Chen, X.1
Barley, K.2
Luo, W.3
Lin, S.H.4
Schilling, W.P.5
-
29
-
-
0029964035
-
Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor
-
Chen, Y., D. Grall, A. E. Salcini, P. G. Pelicci, J. Pouyssegur, and E. Van Obberghen-Schilling. Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor. EMBO J. 15: 1037-1044, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 1037-1044
-
-
Chen, Y.1
Grall, D.2
Salcini, A.E.3
Pelicci, P.G.4
Pouyssegur, J.5
Van Obberghen-Schilling, E.6
-
30
-
-
0027999621
-
Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts
-
Chen, Y. H., J. Pouyssegur, S. A. Courtneidge, and E. Van Obberghen-Schilling. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts. J. Biol. Chem. 269: 27372-27377, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27372-27377
-
-
Chen, Y.H.1
Pouyssegur, J.2
Courtneidge, S.A.3
Van Obberghen-Schilling, E.4
-
31
-
-
0029862685
-
Thrombin functions as an inflammatory mediator through activation of its receptor
-
Cirino, G., C. Cicala, M. R. Bucci, L. Sorrentino, J. M. Maraganore, and S. R. Stone. Thrombin functions as an inflammatory mediator through activation of its receptor. J. Exp. Med. 183: 821-827, 1996.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 821-827
-
-
Cirino, G.1
Cicala, C.2
Bucci, M.R.3
Sorrentino, L.4
Maraganore, J.M.5
Stone, S.R.6
-
32
-
-
0028222277
-
Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
-
Colotta, F., F. L. Sciacca, M. Sironi, W. Luini, M. J. Rabiet, and A. Mantovani. Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am. J. Pathol. 144: 975-985, 1994.
-
(1994)
Am. J. Pathol.
, vol.144
, pp. 975-985
-
-
Colotta, F.1
Sciacca, F.L.2
Sironi, M.3
Luini, W.4
Rabiet, M.J.5
Mantovani, A.6
-
33
-
-
0030008312
-
Role of the thrombin receptor in development and evidence for a second receptor
-
Connolly, A. J., H. Ishihara, M. L. Kahn, R. V. Farese, Jr., and S. R. Coughlin. Role of the thrombin receptor in development and evidence for a second receptor. Nature 381: 516-519, 1996.
-
(1996)
Nature
, vol.381
, pp. 516-519
-
-
Connolly, A.J.1
Ishihara, H.2
Kahn, M.L.3
Farese Jr., R.V.4
Coughlin, S.R.5
-
34
-
-
1842414265
-
Mast cell tryptase regulates colonic myocytes through proteinase-activated receptor-2
-
Corvera, C. U., O. Déry, K. McConalogue, S. K. Böhm, L. M. Khitin, G. H. Caughey, D. G. Payan, and N. W. Bunnett. Mast cell tryptase regulates colonic myocytes through proteinase-activated receptor-2. J. Clin. Invest. 100: 1383-1393, 1997.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1383-1393
-
-
Corvera, C.U.1
Déry, O.2
McConalogue, K.3
Böhm, S.K.4
Khitin, L.M.5
Caughey, G.H.6
Payan, D.G.7
Bunnett, N.W.8
-
35
-
-
0028031081
-
Protease-activated receptors start a family
-
Coughlin, S. R. Protease-activated receptors start a family. Proc. Natl. Acad. Sci. USA 91: 9200-9202, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9200-9202
-
-
Coughlin, S.R.1
-
36
-
-
0030438457
-
Cardiovascular actions of thrombin receptor activation in vivo
-
Damiano, B. P., W. M. Cheung, J. A. Mitchell, and R. Falotico. Cardiovascular actions of thrombin receptor activation in vivo. J. Pharmacol. Exp. Ther. 279: 1365-1378, 1996.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 1365-1378
-
-
Damiano, B.P.1
Cheung, W.M.2
Mitchell, J.A.3
Falotico, R.4
-
37
-
-
8044253419
-
Biological consequences of thrombin receptor deficiency in mice
-
Darrow, A. L., W. P. Fung-Leung, R. D. Ye, R. J. Santulli, W. M. Cheung, C. K. Derian, C. L. Burns, B. P. Damiano, L. Zhou, C. M. Keenan, P. A. Peterson, and P. Andrade-Gordon. Biological consequences of thrombin receptor deficiency in mice. Thromb. Haemost. 76: 860-866, 1996.
-
(1996)
Thromb. Haemost.
, vol.76
, pp. 860-866
-
-
Darrow, A.L.1
Fung-Leung, W.P.2
Ye, R.D.3
Santulli, R.J.4
Cheung, W.M.5
Derian, C.K.6
Burns, C.L.7
Damiano, B.P.8
Zhou, L.9
Keenan, C.M.10
Peterson, P.A.11
Andrade-Gordon, P.12
-
39
-
-
0030741952
-
Differential regulation of human keratinocyte growth and differentiation by a novel family of protease-activated receptors
-
Derian, C. K., A. J. Eckardt, and P. Andrade-Gordon. Differential regulation of human keratinocyte growth and differentiation by a novel family of protease-activated receptors. Cell Growth Differ. 8: 743-749, 1997.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 743-749
-
-
Derian, C.K.1
Eckardt, A.J.2
Andrade-Gordon, P.3
-
40
-
-
0025857712
-
Prothrombin mRNA is expressed by cells of the nervous system
-
Dihanich, M., M. Kaser, E. Reinhard, D. Cunningham, and D. Monard. Prothrombin mRNA is expressed by cells of the nervous system. Neuron 6: 575-581, 1991.
-
(1991)
Neuron
, vol.6
, pp. 575-581
-
-
Dihanich, M.1
Kaser, M.2
Reinhard, E.3
Cunningham, D.4
Monard, D.5
-
41
-
-
0027470910
-
Thrombin is a regulator of astrocytic endothelin-1
-
Ehrenreich, H., T. Costa, K. A. Clouse, R. M. Pluta, Y. Ogino, J. E. Coligan, and P. R. Burd. Thrombin is a regulator of astrocytic endothelin-1. Brain Res. 600: 201-207, 1993.
-
(1993)
Brain Res.
, vol.600
, pp. 201-207
-
-
Ehrenreich, H.1
Costa, T.2
Clouse, K.A.3
Pluta, R.M.4
Ogino, Y.5
Coligan, J.E.6
Burd, P.R.7
-
42
-
-
0028800729
-
Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor
-
Elling, C. E., S. M. Nielsen, and T. W. Schwartz. Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor. Nature 374: 74-77, 1995.
-
(1995)
Nature
, vol.374
, pp. 74-77
-
-
Elling, C.E.1
Nielsen, S.M.2
Schwartz, T.W.3
-
43
-
-
0028208759
-
Phosphoinositide phospholipases and G proteins in hormone action
-
Exton, J. H. Phosphoinositide phospholipases and G proteins in hormone action. Annu. Rev. Physiol. 56: 349-369, 1994.
-
(1994)
Annu. Rev. Physiol.
, vol.56
, pp. 349-369
-
-
Exton, J.H.1
-
44
-
-
0028068960
-
A Chinese hamster fibroblast mutant defective in thrombin-induced signaling has a low level of phospholipase C-β1
-
Fee, J. A., J. D. Monsey, R. J. Handler, M. A. Leonis, S. R. Mullaney, H. M. Hope, and D. F. Silbert. A Chinese hamster fibroblast mutant defective in thrombin-induced signaling has a low level of phospholipase C-β1. J. Biol. Chem. 269: 21699-21708, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21699-21708
-
-
Fee, J.A.1
Monsey, J.D.2
Handler, R.J.3
Leonis, M.A.4
Mullaney, S.R.5
Hope, H.M.6
Silbert, D.F.7
-
45
-
-
0030593035
-
Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
Ferguson, S. S., W. E. Downey, A. M. Colapietro, L. S. Barak, L. Menard, and M. G. Caron. Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271: 363-366, 1996.
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.1
Downey, W.E.2
Colapietro, A.M.3
Barak, L.S.4
Menard, L.5
Caron, M.G.6
-
46
-
-
0028791335
-
Role of phosphorylation in agonist-promoted β2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by β ARK1
-
Ferguson, S. S., L. Menard, L. S. Barak, W. J. Koch, A. M. Colapietro, and M. G. Caron. Role of phosphorylation in agonist-promoted β2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by β ARK1. J. Biol. Chem. 270: 24782-24789, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24782-24789
-
-
Ferguson, S.S.1
Menard, L.2
Barak, L.S.3
Koch, W.J.4
Colapietro, A.M.5
Caron, M.G.6
-
47
-
-
0030007646
-
Thrombin, its receptor and protease nexin I, its potent serpin, in the nervous system
-
Festoff, B. W., I. V. Smirnova, J. Ma, and B. A. Citron. Thrombin, its receptor and protease nexin I, its potent serpin, in the nervous system. Semin. Thromb. Hemost. 22: 267-271, 1996.
-
(1996)
Semin. Thromb. Hemost.
, vol.22
, pp. 267-271
-
-
Festoff, B.W.1
Smirnova, I.V.2
Ma, J.3
Citron, B.A.4
-
48
-
-
0025224154
-
rap1B, a cAMP-dependent protein kinase substrate, associates with the platelet cytoskeleton
-
Fischer, T. H., M. N. Gatling, J. C. Lacal, and G. C. White II. rap1B, a cAMP-dependent protein kinase substrate, associates with the platelet cytoskeleton. J. Biol. Chem. 265: 19405-19408, 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19405-19408
-
-
Fischer, T.H.1
Gatling, M.N.2
Lacal, J.C.3
White II, G.C.4
-
49
-
-
0028283850
-
Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface
-
Gerszten, R. E., J. Chen, M. Ishii, K. Ishii, L. Wang, T. Nanevicz, C. W. Turck, T. K. Vu, and S. R. Coughlin. Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface. Nature 368: 648-651, 1994.
-
(1994)
Nature
, vol.368
, pp. 648-651
-
-
Gerszten, R.E.1
Chen, J.2
Ishii, M.3
Ishii, K.4
Wang, L.5
Nanevicz, T.6
Turck, C.W.7
Vu, T.K.8
Coughlin, S.R.9
-
50
-
-
0027340010
-
Chimeric NK1 (substance P)/NK3 (neurokinin B) receptors. Identification of domains determining the binding specificity of tachykinin agonists
-
Gether, U., T. E. Johansen, and T. W. Schwartz. Chimeric NK1 (substance P)/NK3 (neurokinin B) receptors. Identification of domains determining the binding specificity of tachykinin agonists. J. Biol. Chem. 268: 7893-7898, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7893-7898
-
-
Gether, U.1
Johansen, T.E.2
Schwartz, T.W.3
-
51
-
-
0028076832
-
Specific residues at the top of transmembrane segment V and VI of the neurokinin-1 receptor involved in binding of the nonpeptide antagonist CP 96,345
-
Erratum. J. Biol. Chem. 269: December 1994, p. 32708
-
Gether, U., L. Nilsson, J. A. Lowe III, and T. W. Schwartz. Specific residues at the top of transmembrane segment V and VI of the neurokinin-1 receptor involved in binding of the nonpeptide antagonist CP 96,345. J. Biol. Chem. 269: 23959-23964, 1994. [Erratum. J. Biol. Chem. 269: December 1994, p. 32708.]
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23959-23964
-
-
Gether, U.1
Nilsson, L.2
Lowe III, J.A.3
Schwartz, T.W.4
-
52
-
-
0028293716
-
Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists
-
Godin, D., F. Marceau, C. Beaule, F. Rioux, and G. Drapeau. Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists. Eur. J. Pharmacol. 253: 225-230, 1994.
-
(1994)
Eur. J. Pharmacol.
, vol.253
, pp. 225-230
-
-
Godin, D.1
Marceau, F.2
Beaule, C.3
Rioux, F.4
Drapeau, G.5
-
53
-
-
0029770657
-
β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor
-
Goodman, O. B., Jr., J. G. Krupnick, F. Santini, V. V. Gurevich, R. B. Penn, A. W. Gagnon, J. H. Keen, and J. L. Benovic. β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor. Nature 383: 447-450, 1996.
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman Jr., O.B.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
Gagnon, A.W.6
Keen, J.H.7
Benovic, J.L.8
-
54
-
-
0030032791
-
Cellular consequences of thrombin-receptor activation
-
Grand, R. J., A. S. Turnell, and P. W. Grabham. Cellular consequences of thrombin-receptor activation. Biochem. J. 313: 353-368, 1996.
-
(1996)
Biochem. J.
, vol.313
, pp. 353-368
-
-
Grand, R.J.1
Turnell, A.S.2
Grabham, P.W.3
-
55
-
-
0028279039
-
A novel biologic activity of thrombin: Stimulation of monocyte chemotactic protein production
-
Grandaliano, G., A. J. Valente, and H. E. Abboud. A novel biologic activity of thrombin: stimulation of monocyte chemotactic protein production. J. Exp. Med. 179: 1737-1741, 1994.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1737-1741
-
-
Grandaliano, G.1
Valente, A.J.2
Abboud, H.E.3
-
56
-
-
0027170953
-
Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets
-
Guinebault, C., B. Payrastre, C. Sultan, G. Mauco, M. Breton, S. Levy-Toledano, M. Plantavid, and H. Chap. Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets. Biochem. J. 292: 851-856, 1993.
-
(1993)
Biochem. J.
, vol.292
, pp. 851-856
-
-
Guinebault, C.1
Payrastre, B.2
Sultan, C.3
Mauco, G.4
Breton, M.5
Levy-Toledano, S.6
Plantavid, M.7
Chap, H.8
-
57
-
-
0011811083
-
Thrombin modulates and reverses neuroblastoma neurite outgrowth
-
Gurwitz, D., and D. D. Cunningham. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc. Natl. Acad. Sci. USA 85: 3440-3444, 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 3440-3444
-
-
Gurwitz, D.1
Cunningham, D.D.2
-
58
-
-
0026771255
-
Human tryptase as a potent, cell-specific mitogen: Role of signaling pathways in synergistic responses
-
Lung Cell. Mol. Physiol. 6
-
Hartmann, T., S. J. Ruoss, W. W. Raymond, K. Seuwen, and G. H. Caughey. Human tryptase as a potent, cell-specific mitogen: role of signaling pathways in synergistic responses. Am. J. Physiol. 262 (Lung Cell. Mol. Physiol. 6): L528-L534, 1992.
-
(1992)
Am. J. Physiol.
, vol.262
-
-
Hartmann, T.1
Ruoss, S.J.2
Raymond, W.W.3
Seuwen, K.4
Caughey, G.H.5
-
59
-
-
0028053488
-
Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor
-
Hein, L., K. Ishii, S. R. Coughlin, and B. K. Kobilka. Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor. J. Biol. Chem. 269: 27719-27726, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27719-27726
-
-
Hein, L.1
Ishii, K.2
Coughlin, S.R.3
Kobilka, B.K.4
-
60
-
-
0030030210
-
Protease-mediated signalling: New paradigms for cell regulation and drug development
-
Hollenberg, M. D. Protease-mediated signalling: new paradigms for cell regulation and drug development. Trends Pharmacol. Sci. 17: 3-6, 1996.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 3-6
-
-
Hollenberg, M.D.1
-
61
-
-
0027174547
-
Role of the amino- And carboxyl-terminal domains of thrombin receptor-derived polypeptides in biological activity in vascular endothelium and gastric smooth muscle: Evidence for receptor subtypes
-
Hollenberg, M. D., A. A. Laniyonu, M. Saifeddine, and G. J. Moore. Role of the amino- and carboxyl-terminal domains of thrombin receptor-derived polypeptides in biological activity in vascular endothelium and gastric smooth muscle: evidence for receptor subtypes. Mol. Pharmacol. 43: 921-930, 1993.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 921-930
-
-
Hollenberg, M.D.1
Laniyonu, A.A.2
Saifeddine, M.3
Moore, G.J.4
-
62
-
-
0030044693
-
Proteinase-activated receptor-2 in rat aorta: Structural requirements for agonist activity of receptor-activating peptides
-
Hollenberg, M. D., M. Saifeddine, and B. Al-Ani. Proteinase-activated receptor-2 in rat aorta: structural requirements for agonist activity of receptor-activating peptides. Mol. Pharmacol. 49: 229-233, 1996.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 229-233
-
-
Hollenberg, M.D.1
Saifeddine, M.2
Al-Ani, B.3
-
63
-
-
0028959546
-
The functional thrombin receptor is associated with the plasmalemma and a large endosomal network in cultured human umbilical vein endothelial cells
-
Horvat, R., and G. E. Palade. The functional thrombin receptor is associated with the plasmalemma and a large endosomal network in cultured human umbilical vein endothelial cells. J. Cell Sci. 108: 1155-1164, 1995.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 1155-1164
-
-
Horvat, R.1
Palade, G.E.2
-
64
-
-
0027231264
-
Peripheral blood lymphocytes express the platelet-type thrombin receptor
-
Howells, G. L., M. Macey, M. A. Curtis, and S. R. Stone. Peripheral blood lymphocytes express the platelet-type thrombin receptor. Br. J. Haematol. 84: 156-160, 1993.
-
(1993)
Br. J. Haematol.
, vol.84
, pp. 156-160
-
-
Howells, G.L.1
Macey, M.2
Curtis, M.A.3
Stone, S.R.4
-
65
-
-
0030987215
-
Proteinase-activated receptor-2: Expression by human neutrophils
-
Howells, G. L., M. G. Macey, C. Chinni, L. Hou, M. T. Fox, P. Harriott, and S. R. Stone. Proteinase-activated receptor-2: expression by human neutrophils. J. Cell Sci. 110: 881-887, 1997.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 881-887
-
-
Howells, G.L.1
Macey, M.G.2
Chinni, C.3
Hou, L.4
Fox, M.T.5
Harriott, P.6
Stone, S.R.7
-
66
-
-
0027378281
-
Internalization and recycling of activated thrombin receptors
-
Hoxie, J. A., M. Ahuja, E. Belmonte, S. Pizarro, R. Parton, and L. F. Brass. Internalization and recycling of activated thrombin receptors. J. Biol. Chem. 268: 13756-13763, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 13756-13763
-
-
Hoxie, J.A.1
Ahuja, M.2
Belmonte, E.3
Pizarro, S.4
Parton, R.5
Brass, L.F.6
-
67
-
-
0026690665
-
Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation
-
Hung, D. T., T. K. Vu, V. I. Wheaton, K. Ishii, and S. R. Coughlin. Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation. J. Clin. Invest. 89: 1350-1353, 1992
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 1350-1353
-
-
Hung, D.T.1
Vu, T.K.2
Wheaton, V.I.3
Ishii, K.4
Coughlin, S.R.5
-
68
-
-
0026782001
-
The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase
-
Hung, D. T., Y. H. Wong, T. K. Vu, and S. R. Coughlin. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase. J. Biol. Chem. 267: 20831-20834, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20831-20834
-
-
Hung, D.T.1
Wong, Y.H.2
Vu, T.K.3
Coughlin, S.R.4
-
69
-
-
0029979497
-
Evidence for the presence of a proteinase-activated receptor distinct from the thrombin receptor in vascular endothelial cells
-
Hwa, J. J., L. Ghibaudi, P. Williams, M. Chintala, R. Zhang, M. Chatterjee, and E. Sybertz. Evidence for the presence of a proteinase-activated receptor distinct from the thrombin receptor in vascular endothelial cells. Circ. Res. 78: 581-588, 1996.
-
(1996)
Circ. Res.
, vol.78
, pp. 581-588
-
-
Hwa, J.J.1
Ghibaudi, L.2
Williams, P.3
Chintala, M.4
Zhang, R.5
Chatterjee, M.6
Sybertz, E.7
-
70
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara, H., A. J. Connolly, D. Zeng, M. L. Kahn, Y. W. Zheng, C. Timmons, T. Tram, and S. R. Coughlin. Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386: 502-506, 1997.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
71
-
-
0028009801
-
Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases
-
Ishii, K., J. Chen, M. Ishii, W. J. Koch, N. J. Freedman, R. J. Lefkowitz, and S. R. Coughlin. Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases. J. Biol. Chem. 269: 1125-1130, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1125-1130
-
-
Ishii, K.1
Chen, J.2
Ishii, M.3
Koch, W.J.4
Freedman, N.J.5
Lefkowitz, R.J.6
Coughlin, S.R.7
-
72
-
-
0029026320
-
Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate
-
Ishii, K., R. Gerszten, Y. W. Zheng, J. B. Welsh, C. W. Turck, and S. R. Coughlin. Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate. J. Biol. Chem. 270: 16435-16440, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16435-16440
-
-
Ishii, K.1
Gerszten, R.2
Zheng, Y.W.3
Welsh, J.B.4
Turck, C.W.5
Coughlin, S.R.6
-
73
-
-
0027309290
-
Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling
-
Ishii, K., L. Hein, B. Kobilka, and S. R. Coughlin. Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling. J. Biol. Chem. 268: 9780-9786, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9780-9786
-
-
Ishii, K.1
Hein, L.2
Kobilka, B.3
Coughlin, S.R.4
-
74
-
-
0028021308
-
Inhibition of lysophosphatidate- And thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
-
Jalink, K., E. J. van Corven, T. Hengeveld, N. Morii, S. Narumiya, and W. H. Moolenaar. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell Biol. 126: 801-810, 1994.
-
(1994)
J. Cell Biol.
, vol.126
, pp. 801-810
-
-
Jalink, K.1
Van Corven, E.J.2
Hengeveld, T.3
Morii, N.4
Narumiya, S.5
Moolenaar, W.H.6
-
75
-
-
0027493424
-
Characterization of the receptor responsible for thrombin-induced intracellular calcium responses in osteoblast-like cells
-
Jenkins, A. L., M. D. Bootman, C. W. Taylor, E. J. Mackie, and S. R. Stone. Characterization of the receptor responsible for thrombin-induced intracellular calcium responses in osteoblast-like cells. J. Biol. Chem. 268: 21432-21437, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21432-21437
-
-
Jenkins, A.L.1
Bootman, M.D.2
Taylor, C.W.3
Mackie, E.J.4
Stone, S.R.5
-
76
-
-
0025133268
-
Thrombin and factor Xa enhance the production of interleukin-1
-
Jones, A., and C. L. Geczy. Thrombin and factor Xa enhance the production of interleukin-1. Immunology 71: 236-241, 1990.
-
(1990)
Immunology
, vol.71
, pp. 236-241
-
-
Jones, A.1
Geczy, C.L.2
-
77
-
-
0028839210
-
Thrombin receptor activating peptide (TRAP) stimulates mitogenesis, c-fos and PDGF-A gene expression in human vascular smooth muscle cells
-
Kanthou, C., O. Benzakour, G. Patel, J. Deadman, V. V. Kakkar, and F. Lupu. Thrombin receptor activating peptide (TRAP) stimulates mitogenesis, c-fos and PDGF-A gene expression in human vascular smooth muscle cells. Thromb. Haemost. 74: 1340-1347, 1995.
-
(1995)
Thromb. Haemost.
, vol.74
, pp. 1340-1347
-
-
Kanthou, C.1
Benzakour, O.2
Patel, G.3
Deadman, J.4
Kakkar, V.V.5
Lupu, F.6
-
78
-
-
0025738895
-
Protein kinase C regulates the stimulated accumulation of 3-phosphorylated phosphoinositides in platelets
-
King, W. G., G. L. Kucera, A. Sorisky, J. Zhang, and S. E. Rittenhouse. Protein kinase C regulates the stimulated accumulation of 3-phosphorylated phosphoinositides in platelets. Biochem. J. 278: 475-480, 1991.
-
(1991)
Biochem. J.
, vol.278
, pp. 475-480
-
-
King, W.G.1
Kucera, G.L.2
Sorisky, A.3
Zhang, J.4
Rittenhouse, S.E.5
-
79
-
-
0027231364
-
Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets
-
Kinlough-Rathbone, R. L., M. L. Rand, and M. A. Packham. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood 82: 103-106, 1993.
-
(1993)
Blood
, vol.82
, pp. 103-106
-
-
Kinlough-Rathbone, R.L.1
Rand, M.L.2
Packham, M.A.3
-
80
-
-
0027481431
-
Thrombin stimulates melanoma tumor-cell binding to endothelial cells and subendothelial matrix
-
Klepfish, A., M. A. Greco, and S. Karpatkin. Thrombin stimulates melanoma tumor-cell binding to endothelial cells and subendothelial matrix. Int. J. Cancer 53: 978-982, 1993.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 978-982
-
-
Klepfish, A.1
Greco, M.A.2
Karpatkin, S.3
-
81
-
-
8044259613
-
The involvement of a novel mechanism distinct from the thrombin receptor in the vasocontraction induced by trypsin
-
Komuro, T., S. Miwa, T. Minowa, Y. Okamoto, T. Enoki, H. Ninomiya, X. F. Zhang, Y. Uemura, H. Kikuchi, and T. Masaki. The involvement of a novel mechanism distinct from the thrombin receptor in the vasocontraction induced by trypsin. Br. J. Pharmacol. 120: 851-856, 1997.
-
(1997)
Br. J. Pharmacol.
, vol.120
, pp. 851-856
-
-
Komuro, T.1
Miwa, S.2
Minowa, T.3
Okamoto, Y.4
Enoki, T.5
Ninomiya, H.6
Zhang, X.F.7
Uemura, Y.8
Kikuchi, H.9
Masaki, T.10
-
82
-
-
0030741026
-
Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2
-
Kong, W., K. McConalogue, L. M. Khitin, M. D. Hollenberg, D. G. Payan, S. K. Bohm, and N. W. Bunnett. Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2. Proc. Natl. Acad. Sci. USA 94: 8884-8889, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8884-8889
-
-
Kong, W.1
McConalogue, K.2
Khitin, L.M.3
Hollenberg, M.D.4
Payan, D.G.5
Bohm, S.K.6
Bunnett, N.W.7
-
83
-
-
0030742507
-
Expression of trypsin in vascular endothelial cells
-
Koshikawa, N., Y. Nagashima, Y. Miyagi, H. Mizushima, S. Yanoma, H. Yasumitsu, and K. Miyazaki. Expression of trypsin in vascular endothelial cells. FEBS Lett. 409: 442-448, 1997.
-
(1997)
FEBS Lett.
, vol.409
, pp. 442-448
-
-
Koshikawa, N.1
Nagashima, Y.2
Miyagi, Y.3
Mizushima, H.4
Yanoma, S.5
Yasumitsu, H.6
Miyazaki, K.7
-
84
-
-
0022600508
-
Mechanism of thrombin-induced endothelium-dependent coronary vasodilation in dogs: Role of its proteolytic enzymatic activity
-
Ku, D. D. Mechanism of thrombin-induced endothelium-dependent coronary vasodilation in dogs: role of its proteolytic enzymatic activity. J. Cardiovasc. Pharmacol. 8: 29-36, 1986.
-
(1986)
J. Cardiovasc. Pharmacol.
, vol.8
, pp. 29-36
-
-
Ku, D.D.1
-
85
-
-
0026202049
-
p42/ Mitogen-activated protein kinase as a converging target for different growth factor signaling pathways: Use of pertussis toxin as a discrimination factor
-
L'Allemain, G., J. Pouyssegur, and M. J. Weber. p42/ Mitogen-activated protein kinase as a converging target for different growth factor signaling pathways: use of pertussis toxin as a discrimination factor. Cell Regul. 2: 675-684, 1991.
-
(1991)
Cell Regul.
, vol.2
, pp. 675-684
-
-
L'Allemain, G.1
Pouyssegur, J.2
Weber, M.J.3
-
86
-
-
0020557296
-
Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro
-
Laposata, M., D. K. Dovnarsky, and H. S. Shin. Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro. Blood 62: 549-556, 1983.
-
(1983)
Blood
, vol.62
, pp. 549-556
-
-
Laposata, M.1
Dovnarsky, D.K.2
Shin, H.S.3
-
87
-
-
0028080979
-
Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators
-
Lau, L. F., K. Pumiglia, Y. P. Cote, and M. B. Feinstein. Thrombin-receptor agonist peptides, in contrast to thrombin itself, are not full agonists for activation and signal transduction in human platelets in the absence of platelet-derived secondary mediators. Biochem. J. 303: 391-400, 1994.
-
(1994)
Biochem. J.
, vol.303
, pp. 391-400
-
-
Lau, L.F.1
Pumiglia, K.2
Cote, Y.P.3
Feinstein, M.B.4
-
88
-
-
0029943079
-
Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function
-
Lerner, D. J., M. Chen, T. Tram, and S. R. Coughlin. Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function. J. Biol. Chem. 271: 13943-13947, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13943-13947
-
-
Lerner, D.J.1
Chen, M.2
Tram, T.3
Coughlin, S.R.4
-
89
-
-
0027418080
-
Thrombin receptor peptide inhibits thrombin-induced increase in endothelial permeability by receptor desensitization
-
Lum, H., T. T. Andersen, A. Siflinger-Birnboim, C. Tiruppathi, M. S. Goligorsky, J. W. Fenton II, and A. B. Malik. Thrombin receptor peptide inhibits thrombin-induced increase in endothelial permeability by receptor desensitization. J. Cell Biol. 120: 1491-1499, 1993.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 1491-1499
-
-
Lum, H.1
Andersen, T.T.2
Siflinger-Birnboim, A.3
Tiruppathi, C.4
Goligorsky, M.S.5
Fenton II, J.W.6
Malik, A.B.7
-
90
-
-
0026782933
-
2+ and inositol polyphosphates
-
Lung Cell. Mol. Physiol. 7: L219-L225, Corrigenda. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): October 1992, following table of contents
-
2+ and inositol polyphosphates. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L219-L225, 1992. [Corrigenda. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): October 1992, following table of contents.]
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Lum, H.1
Aschner, J.L.2
Phillips, P.G.3
Fletcher, P.W.4
Malik, A.B.5
-
91
-
-
0029670360
-
Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors
-
Mari, B., S. Guerin, D. F. Far, J. P. Breitmayer, N. Belhacene, J. F. Peyron, B. Rossi, and P. Auberger. Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors. FASEB J. 10: 309-316, 1996.
-
(1996)
FASEB J.
, vol.10
, pp. 309-316
-
-
Mari, B.1
Guerin, S.2
Far, D.F.3
Breitmayer, J.P.4
Belhacene, N.5
Peyron, J.F.6
Rossi, B.7
Auberger, P.8
-
92
-
-
0027492461
-
Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor
-
McNamara, C. A., I. J. Sarembock, L. W. Gimple, J. W. Fenton II, S. R. Coughlin, and G. K. Owens. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J. Clin. Invest. 91: 94-98, 1993.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 94-98
-
-
McNamara, C.A.1
Sarembock, I.J.2
Gimple, L.W.3
Fenton II, J.W.4
Coughlin, S.R.5
Owens, G.K.6
-
93
-
-
0029992037
-
Members of the G protein-coupled receptor kinase family that phosphorylate the β2-adrenergic receptor facilitate sequestration
-
Menard, L., S. S. Ferguson, L. S. Barak, L. Bertrand, R. T. Premont, A. M. Colapietro, R. J. Lefkowitz, and M. G. Caron. Members of the G protein-coupled receptor kinase family that phosphorylate the β2-adrenergic receptor facilitate sequestration. Biochemistry 35: 4155-4160, 1996.
-
(1996)
Biochemistry
, vol.35
, pp. 4155-4160
-
-
Menard, L.1
Ferguson, S.S.2
Barak, L.S.3
Bertrand, L.4
Premont, R.T.5
Colapietro, A.M.6
Lefkowitz, R.J.7
Caron, M.G.8
-
94
-
-
0029790022
-
Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5
-
Miller, S., N. Sehati, C. Romano, and C. W. Cotman. Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5. J. Neurochem. 67: 1435-1447, 1996.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1435-1447
-
-
Miller, S.1
Sehati, N.2
Romano, C.3
Cotman, C.W.4
-
95
-
-
0030003829
-
The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells
-
Mirza, H., V. Yatsula, and W. F. Bahou. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. J. Clin. Invest. 97: 1705-1714, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1705-1714
-
-
Mirza, H.1
Yatsula, V.2
Bahou, W.F.3
-
96
-
-
0031041906
-
Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation
-
Molino, M., D. F. Bainton, J. A. Hoxie, S. R. Coughlin, and L. F. Brass. Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation. J. Biol. Chem. 272: 6011-6017, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6011-6017
-
-
Molino, M.1
Bainton, D.F.2
Hoxie, J.A.3
Coughlin, S.R.4
Brass, L.F.5
-
97
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino, M., E. S. Barnathan, R. Numerof, J. Clark, M. Dreyer, A. Cumashi, J. Hoxie, N. Schechter, M. Woolkalis, and L. F. Brass. Interactions of mast cell tryptase with thrombin receptors and PAR-2. J. Biol. Chem. 272: 4043-4049, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
Clark, J.4
Dreyer, M.5
Cumashi, A.6
Hoxie, J.7
Schechter, N.8
Woolkalis, M.9
Brass, L.F.10
-
98
-
-
0029018204
-
Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G
-
Molino, M., N. Blanchard, E. Belmonte, A. P. Tarver, C. Abrams, J. A. Hoxie, C. Cerletti, and L. F. Brass. Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G. J. Biol. Chem. 270: 11168-11175, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11168-11175
-
-
Molino, M.1
Blanchard, N.2
Belmonte, E.3
Tarver, A.P.4
Abrams, C.5
Hoxie, J.A.6
Cerletti, C.7
Brass, L.F.8
-
99
-
-
0029865197
-
Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells: Evidence for an obligate autocrine mechanism promoting cell proliferation induced by G-protein-coupled receptor agonist
-
Molloy, C. J., J. E. Pawlowski, D. S. Taylor, C. E. Turner, H. Weber, and M. Peluso. Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for an obligate autocrine mechanism promoting cell proliferation induced by G-protein-coupled receptor agonist. J. Clin. Invest. 97: 1173-1183, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1173-1183
-
-
Molloy, C.J.1
Pawlowski, J.E.2
Taylor, D.S.3
Turner, C.E.4
Weber, H.5
Peluso, M.6
-
100
-
-
0027957994
-
Thrombin in inflammation and healing: Relevance to rheumatoid arthritis
-
Morris, R., P. G. Winyard, D. R. Blake, and C. J. Morris. Thrombin in inflammation and healing: relevance to rheumatoid arthritis. Ann. Rheum. Dis. 53: 72-79, 1994.
-
(1994)
Ann. Rheum. Dis.
, vol.53
, pp. 72-79
-
-
Morris, R.1
Winyard, P.G.2
Blake, D.R.3
Morris, C.J.4
-
101
-
-
0029831183
-
Thrombin receptor expression in rheumatoid and osteoarthritic synovial tissue
-
Morris, R., P. G. Winyard, L. F. Brass, D. R. Blake, and C. J. Morris. Thrombin receptor expression in rheumatoid and osteoarthritic synovial tissue. Ann. Rheum. Dis. 55: 841-843, 1996.
-
(1996)
Ann. Rheum. Dis.
, vol.55
, pp. 841-843
-
-
Morris, R.1
Winyard, P.G.2
Brass, L.F.3
Blake, D.R.4
Morris, C.J.5
-
102
-
-
0025173004
-
Promotion of transendothelial neutrophil passage by human thrombin
-
Moser, R., P. Groscurth, and J. Fehr. Promotion of transendothelial neutrophil passage by human thrombin. J. Cell Sci. 96: 737-744, 1990.
-
(1990)
J. Cell Sci.
, vol.96
, pp. 737-744
-
-
Moser, R.1
Groscurth, P.2
Fehr, J.3
-
103
-
-
0026475058
-
Vascular actions of thrombin receptor peptide
-
Muramatsu, I., A. Laniyonu, G. J. Moore, and M. D. Hollenberg. Vascular actions of thrombin receptor peptide. Can. J. Physiol. Pharmacol. 70: 996-1003, 1992.
-
(1992)
Can. J. Physiol. Pharmacol.
, vol.70
, pp. 996-1003
-
-
Muramatsu, I.1
Laniyonu, A.2
Moore, G.J.3
Hollenberg, M.D.4
-
104
-
-
0029143923
-
Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site
-
Nanevicz, T., M. Ishii, L. Wang, M. Chen, J. Chen, C. W. Turck, F. E. Cohen, and S. R. Coughlin. Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site. J. Biol. Chem. 270: 21619-21625, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21619-21625
-
-
Nanevicz, T.1
Ishii, M.2
Wang, L.3
Chen, M.4
Chen, J.5
Turck, C.W.6
Cohen, F.E.7
Coughlin, S.R.8
-
105
-
-
0030066317
-
Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitu-tive signaling
-
Nanevicz, T., L. Wang, M. Chen, M. Ishii, and S. R. Coughlin. Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitu-tive signaling. J. Biol. Chem. 271: 702-706, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 702-706
-
-
Nanevicz, T.1
Wang, L.2
Chen, M.3
Ishii, M.4
Coughlin, S.R.5
-
106
-
-
0021714636
-
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing
-
Nawa, H., H. Kotani, and S. Nakanishi. Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing. Nature 312: 729-734, 1984.
-
(1984)
Nature
, vol.312
, pp. 729-734
-
-
Nawa, H.1
Kotani, H.2
Nakanishi, S.3
-
107
-
-
0026497368
-
Thrombin receptor expression in normal and atherosclerotic human arteries
-
Nelken, N. A., S. J. Soifer, J. O'Keefe, T. K. Vu, I. F. Charo, and S. R. Coughlin. Thrombin receptor expression in normal and atherosclerotic human arteries. J. Clin. Invest. 90: 1614-1621, 1992.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1614-1621
-
-
Nelken, N.A.1
Soifer, S.J.2
O'Keefe, J.3
Vu, T.K.4
Charo, I.F.5
Coughlin, S.R.6
-
108
-
-
0027510492
-
Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: A possible involvement of thrombin
-
Neveu, I., F. Jehan, M. Jandrot-Perrus, D. Wion, and P. Brachet. Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: a possible involvement of thrombin. J. Neurochem. 60: 858-867, 1993.
-
(1993)
J. Neurochem.
, vol.60
, pp. 858-867
-
-
Neveu, I.1
Jehan, F.2
Jandrot-Perrus, M.3
Wion, D.4
Brachet, P.5
-
109
-
-
0028435633
-
Expression of the thrombin receptor mRNA in rat brain
-
Niclou, S., H. S. Suidan, M. Brown-Luedi, and D. Monard. Expression of the thrombin receptor mRNA in rat brain. Cell. Mol. Biol. (Noisy-le-grand) 40: 421-428, 1994.
-
(1994)
Cell. Mol. Biol. (Noisy-le-grand)
, vol.40
, pp. 421-428
-
-
Niclou, S.1
Suidan, H.S.2
Brown-Luedi, M.3
Monard, D.4
-
110
-
-
0030071886
-
Presence of the seven transmembrane thrombin receptor on human tumour cells: Effect of activation on tumour adhesion to platelets and tumor tyrosine phosphorylation
-
Nierodzik, M. L., R. M. Bain, L. X. Liu, M. Shivji, K. Takeshita, and S. Karpatkin. Presence of the seven transmembrane thrombin receptor on human tumour cells: effect of activation on tumour adhesion to platelets and tumor tyrosine phosphorylation. Br. J. Haematol. 92: 452-457, 1996.
-
(1996)
Br. J. Haematol.
, vol.92
, pp. 452-457
-
-
Nierodzik, M.L.1
Bain, R.M.2
Liu, L.X.3
Shivji, M.4
Takeshita, K.5
Karpatkin, S.6
-
111
-
-
0026684801
-
Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo
-
Nierodzik, M. L., F. Kajumo, and S. Karpatkin. Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo. Cancer Res. 52: 3267-3272, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 3267-3272
-
-
Nierodzik, M.L.1
Kajumo, F.2
Karpatkin, S.3
-
112
-
-
0027488033
-
Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: Evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment
-
Norton, K. J., R. M. Scarborough, J. L. Kutok, M. A. Escobedo, L. Nannizzi, and B. S. Coller. Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment. Blood 82: 2125-2136, 1993.
-
(1993)
Blood
, vol.82
, pp. 2125-2136
-
-
Norton, K.J.1
Scarborough, R.M.2
Kutok, J.L.3
Escobedo, M.A.4
Nannizzi, L.5
Coller, B.S.6
-
113
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt, S., K. Emilsson, A. K. Larsson, B. Strombeck, and J. Sundelin. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur. J. Biochem. 232: 84-89, 1995.
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
114
-
-
0027933068
-
Molecular cloning of a potential proteinase activated receptor
-
Nystedt, S., K. Emilsson, C. Wahlestedt, and J. Sundelin. Molecular cloning of a potential proteinase activated receptor. Proc. Natl. Acad. Sci. USA 91: 9208-9212, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9208-9212
-
-
Nystedt, S.1
Emilsson, K.2
Wahlestedt, C.3
Sundelin, J.4
-
115
-
-
0028934047
-
The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression
-
Nystedt, S., A. K. Larsson, H. Aberg, and J. Sundelin. The mouse proteinase-activated receptor-2 cDNA and gene. Molecular cloning and functional expression. J. Biol. Chem. 270: 5950-5955, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5950-5955
-
-
Nystedt, S.1
Larsson, A.K.2
Aberg, H.3
Sundelin, J.4
-
116
-
-
15844401726
-
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
-
Nystedt, S., V. Ramakrishnan, and J. Sundelin. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J. Biol. Chem. 271: 14910-14915, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14910-14915
-
-
Nystedt, S.1
Ramakrishnan, V.2
Sundelin, J.3
-
117
-
-
0028179510
-
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
-
Offermanns, S., K. L. Laugwitz, K. Spicher, and G. Schultz. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc. Natl. Acad. Sci. USA 91: 504-508, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 504-508
-
-
Offermanns, S.1
Laugwitz, K.L.2
Spicher, K.3
Schultz, G.4
-
118
-
-
0027523466
-
Neurotransmitter functions of mammalian tachykinins
-
Otsuka, M., and K. Yoshioka. Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73: 229-308, 1993.
-
(1993)
Physiol. Rev.
, vol.73
, pp. 229-308
-
-
Otsuka, M.1
Yoshioka, K.2
-
119
-
-
0028174007
-
p42 Mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation
-
Papkoff, J., R. H. Chen, J. Blenis, and J. Foreman. p42 Mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation. Mol. Cell. Biol. 14: 463-472, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 463-472
-
-
Papkoff, J.1
Chen, R.H.2
Blenis, J.3
Foreman, J.4
-
120
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma, J., L. Duprez, J. V. Sande, P. Cochaux, C. Gervy, J. Mockel, J. Dumont, and G. Vassarg. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 365: 649-651, 1993.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Sande, J.V.3
Cochaux, P.4
Gervy, C.5
Mockel, J.6
Dumont, J.7
Vassarg, G.8
-
121
-
-
0023944986
-
Proliferation of rat astrocytes, but not of oligodendrocytes, is stimulated in vitro by protease inhibitors
-
Perraud, F., F. Besnard, G. Labourdette, and M. Sensenbrenner. Proliferation of rat astrocytes, but not of oligodendrocytes, is stimulated in vitro by protease inhibitors. Int. J. Dev. Neurosci. 6: 261-266, 1988.
-
(1988)
Int. J. Dev. Neurosci.
, vol.6
, pp. 261-266
-
-
Perraud, F.1
Besnard, F.2
Labourdette, G.3
Sensenbrenner, M.4
-
122
-
-
0023517177
-
Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts and neuroblasts in primary culture
-
Perraud, F., F. Besnard, M. Sensenbrenner, and G. Labourdette. Thrombin is a potent mitogen for rat astroblasts but not for oligodendroblasts and neuroblasts in primary culture. Int. J. Dev. Neurosci. 5: 181-188, 1987.
-
(1987)
Int. J. Dev. Neurosci.
, vol.5
, pp. 181-188
-
-
Perraud, F.1
Besnard, F.2
Sensenbrenner, M.3
Labourdette, G.4
-
123
-
-
0029914487
-
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro
-
Pike, C. J., P. J. Vaughan, D. D. Cunningham, and C. W. Cotman. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by β-amyloid in vitro. J. Neurochem. 66: 1374-1382, 1996.
-
(1996)
J. Neurochem.
, vol.66
, pp. 1374-1382
-
-
Pike, C.J.1
Vaughan, P.J.2
Cunningham, D.D.3
Cotman, C.W.4
-
124
-
-
0029990852
-
Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells
-
Post, G. R., L. R. Collins, E. D. Kennedy, S. A. Moskowitz, A. M. Aragay, D. Goldstein, and J. H. Brown. Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells. Mol. Biol. Cell 7: 1679-1690, 1996.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 1679-1690
-
-
Post, G.R.1
Collins, L.R.2
Kennedy, E.D.3
Moskowitz, S.A.4
Aragay, A.M.5
Goldstein, D.6
Brown, J.H.7
-
125
-
-
0021745338
-
Thrombin-induced degranulation of cultured bone marrow-derived mast cells
-
Razin, E., and G. Marx. Thrombin-induced degranulation of cultured bone marrow-derived mast cells. J. Immunol. 133: 3282-3285, 1984.
-
(1984)
J. Immunol.
, vol.133
, pp. 3282-3285
-
-
Razin, E.1
Marx, G.2
-
126
-
-
0030968521
-
Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: Evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor
-
Renesto, P., M. Si-Tahar, M. Moniatte, V. Balloy, A. Van Dorsselaer, D. Pidard, and M. Chignard. Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor. Blood 89: 1944-1953, 1997.
-
(1997)
Blood
, vol.89
, pp. 1944-1953
-
-
Renesto, P.1
Si-Tahar, M.2
Moniatte, M.3
Balloy, V.4
Van Dorsselaer, A.5
Pidard, D.6
Chignard, M.7
-
127
-
-
0027475050
-
Neutral endopeptidase 24.11: Structure, inhibition, and experimental and clinical pharmacology
-
Roques, B. P., F. Noble, V. Dauge, M. C. Fournie-Zaluski, and A. Beaumont. Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology. Pharmacol. Rev. 45: 87-146, 1993.
-
(1993)
Pharmacol. Rev.
, vol.45
, pp. 87-146
-
-
Roques, B.P.1
Noble, F.2
Dauge, V.3
Fournie-Zaluski, M.C.4
Beaumont, A.5
-
128
-
-
0041022398
-
β-Adrenergic receptor kinase (GRK2) colocalizes with β-adrenergic receptors during agonist-induced receptor internalization
-
Ruiz-Gomez, A., and F. Mayor. β-Adrenergic receptor kinase (GRK2) colocalizes with β-adrenergic receptors during agonist-induced receptor internalization. J. Biol. Chem. 272: 9601-9604, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9601-9604
-
-
Ruiz-Gomez, A.1
Mayor, F.2
-
129
-
-
0025864033
-
Mast cell tryptase is a mitogen for cultured fibroblasts
-
Ruoss, S., T. Hartmann, and G. Caughey. Mast cell tryptase is a mitogen for cultured fibroblasts. J. Clin. Invest. 88: 493-499, 1991.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 493-499
-
-
Ruoss, S.1
Hartmann, T.2
Caughey, G.3
-
130
-
-
0030008482
-
Rat proteinase-activated receptor-2 (PAR-2): CDNA sequence and activity of receptor-derived peptides and in gastric and vascular tissue
-
Saifeddine, M., B. Al-Ani, C. Cheng, L. Wang, and M. Hollenberg. Rat proteinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides and in gastric and vascular tissue. Br. J. Pharmacol. 118: 521-530, 1996.
-
(1996)
Br. J. Pharmacol.
, vol.118
, pp. 521-530
-
-
Saifeddine, M.1
Al-Ani, B.2
Cheng, C.3
Wang, L.4
Hollenberg, M.5
-
131
-
-
0029021942
-
Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes
-
Santulli, R. J., C. K. Derian, A. L. Darrow, K. A. Tomko, A. J. Eckardt, M. Seiberg, R. M. Scarborough, and P. Andrade-Gordon. Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes. Proc. Natl. Acad. Sci. USA 92: 9151-9155, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9151-9155
-
-
Santulli, R.J.1
Derian, C.K.2
Darrow, A.L.3
Tomko, K.A.4
Eckardt, A.J.5
Seiberg, M.6
Scarborough, R.M.7
Andrade-Gordon, P.8
-
132
-
-
0030598870
-
Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide
-
Satoh, K., Y. Ozaki, N. Asazuma, Y. Yatomi, Q. Ruomei, K. Kuroda, L. Yang, and S. Kume. Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide. Biochem. Biophys. Res. Commun. 225: 1084-1089, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 1084-1089
-
-
Satoh, K.1
Ozaki, Y.2
Asazuma, N.3
Yatomi, Y.4
Ruomei, Q.5
Kuroda, K.6
Yang, L.7
Kume, S.8
-
133
-
-
0026629249
-
Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
-
Scarborough, R. M., M. A. Naughton, W. Teng, D. T. Hung, J. Rose, T. K. Vu, V. I. Wheaton, C. W. Turck, and S. R. Coughlin. Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. J. Biol. Chem. 267: 13146-13149, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13146-13149
-
-
Scarborough, R.M.1
Naughton, M.A.2
Teng, W.3
Hung, D.T.4
Rose, J.5
Vu, T.K.6
Wheaton, V.I.7
Turck, C.W.8
Coughlin, S.R.9
-
134
-
-
0031581816
-
2+, prostacyclin, or permeability
-
2+, prostacyclin, or permeability. Biochem. Pharmacol. 53: 487-491, 1997.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 487-491
-
-
Schaeffer, P.1
Riera, E.2
Dupuy, E.3
Herbert, J.M.4
-
135
-
-
0030946582
-
The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13
-
Schmidt, V. A., W. C. Nierman, T. V. Feldblyum, D. R. Maglott, and W. F. Bahou. The human thrombin receptor and proteinase activated receptor-2 genes are tightly linked on chromosome 5q13. Br. J. Haematol. 97: 523-529, 1997.
-
(1997)
Br. J. Haematol.
, vol.97
, pp. 523-529
-
-
Schmidt, V.A.1
Nierman, W.C.2
Feldblyum, T.V.3
Maglott, D.R.4
Bahou, W.F.5
-
136
-
-
0029919173
-
Genomic cloning and characterization of the human thrombin receptor gene. Structural similarity to the proteinase activated receptor-2 gene
-
Schmidt, V. A., E. Vitale, and W. F. Bahou. Genomic cloning and characterization of the human thrombin receptor gene. Structural similarity to the proteinase activated receptor-2 gene. J. Biol. Chem. 271: 9307-9312, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9307-9312
-
-
Schmidt, V.A.1
Vitale, E.2
Bahou, W.F.3
-
137
-
-
0028850759
-
+ exchange by a thrombin receptor antagonist
-
+ exchange by a thrombin receptor antagonist. Biochem. Pharmacol. 49: 519-528, 1995.
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 519-528
-
-
Seiler, S.M.1
Peluso, M.2
Michel, I.M.3
Goldenberg, H.4
Fenton II, J.W.5
Riexinger, D.6
Natarajan, S.7
-
138
-
-
0030478939
-
Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization
-
Shapiro, M. J., J. Trejo, D. Zeng, and S. R. Coughlin. Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization. J. Biol. Chem. 271: 32874-32880, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32874-32880
-
-
Shapiro, M.J.1
Trejo, J.2
Zeng, D.3
Coughlin, S.R.4
-
139
-
-
0027372340
-
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
-
Shenker, S., L. Laue, S. Kosugi, J. J. Merendino, T. Minegishi, and G. B. Cutler. A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature 365: 652-654, 1993.
-
(1993)
Nature
, vol.365
, pp. 652-654
-
-
Shenker, S.1
Laue, L.2
Kosugi, S.3
Merendino, J.J.4
Minegishi, T.5
Cutler, G.B.6
-
140
-
-
0029095342
-
Thrombin receptor-mediated synovial proliferation in patients with rheumatoid arthritis
-
Shin, H., T. Nakajima, I. Kitajima, K. Shigeta, K. Abeyama, T. Imamura, T. Okano, K. Kawahara, T. Nakamura, and I. Maruyama. Thrombin receptor-mediated synovial proliferation in patients with rheumatoid arthritis. Clin. Immunol. Immunopathol. 76: 225-233, 1995.
-
(1995)
Clin. Immunol. Immunopathol.
, vol.76
, pp. 225-233
-
-
Shin, H.1
Nakajima, T.2
Kitajima, I.3
Shigeta, K.4
Abeyama, K.5
Imamura, T.6
Okano, T.7
Kawahara, K.8
Nakamura, T.9
Maruyama, I.10
-
141
-
-
0031036735
-
Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C
-
Shock, D. D., K. He, J. D. Wencel-Drake, and L. V. Parise. Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C. Biochem. J. 321: 525-530, 1997.
-
(1997)
Biochem. J.
, vol.321
, pp. 525-530
-
-
Shock, D.D.1
He, K.2
Wencel-Drake, J.D.3
Parise, L.V.4
-
142
-
-
0025834532
-
Diversity of G proteins in signal transduction
-
Simon, M., M. Strathmann, and N. Gautam. Diversity of G proteins in signal transduction. Science 252: 802-808, 1991.
-
(1991)
Science
, vol.252
, pp. 802-808
-
-
Simon, M.1
Strathmann, M.2
Gautam, N.3
-
143
-
-
0029134929
-
Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons
-
Smith-Swintosky, V. L., S. Zimmer, J. W. Fenton II, and M. P. Mattson. Opposing actions of thrombin and protease nexin-1 on amyloid β-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons. J. Neurochem. 65: 1415-1418, 1995.
-
(1995)
J. Neurochem.
, vol.65
, pp. 1415-1418
-
-
Smith-Swintosky, V.L.1
Zimmer, S.2
Fenton II, J.W.3
Mattson, M.P.4
-
144
-
-
0026795027
-
Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism
-
Sugama, Y., and A. B. Malik. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ. Res. 71: 1015-1019, 1992.
-
(1992)
Circ. Res.
, vol.71
, pp. 1015-1019
-
-
Sugama, Y.1
Malik, A.B.2
-
145
-
-
0028059276
-
Granzyme Areleased upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes
-
Suidan, H. S., J. Bouvier, E. Schaerer, S. R. Stone, D. Monard, and J. Tschopp. Granzyme Areleased upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes. Proc. Natl. Acad. Sci. USA 91: 8112-8116, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8112-8116
-
-
Suidan, H.S.1
Bouvier, J.2
Schaerer, E.3
Stone, S.R.4
Monard, D.5
Tschopp, J.6
-
146
-
-
0029871382
-
The serine protease granzyme a does not induce platelet aggregation but inhibits responses triggered by thrombin
-
Suidan, H. S., K J. Clemetson, M. Brown-Luedi, S. P. Niclou, J. M. Clemetson, J. Tschopp, and D. Monard. The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin. Biochem. J. 315: 939-945, 1996.
-
(1996)
Biochem. J.
, vol.315
, pp. 939-945
-
-
Suidan, H.S.1
Clemetson, K.J.2
Brown-Luedi, M.3
Niclou, S.P.4
Clemetson, J.M.5
Tschopp, J.6
Monard, D.7
-
147
-
-
0029047721
-
Contractile actions of thrombin receptor-derived polypeptides in human umbilical and placental vasculature: Evidence for distinct receptor systems
-
Tay-Uyboco, J., M. C. Poon, S. Ahmad, and M. D. Hollenberg. Contractile actions of thrombin receptor-derived polypeptides in human umbilical and placental vasculature: evidence for distinct receptor systems. Br. J. Pharmacol. 115: 569-578, 1995.
-
(1995)
Br. J. Pharmacol.
, vol.115
, pp. 569-578
-
-
Tay-Uyboco, J.1
Poon, M.C.2
Ahmad, S.3
Hollenberg, M.D.4
-
148
-
-
0028061845
-
Thrombin receptor-mediated vascular relaxation differentiated by a receptor antagonist and desensitization
-
Heart Circ. Physiol. 36
-
Tesfamariam, B. Thrombin receptor-mediated vascular relaxation differentiated by a receptor antagonist and desensitization. Am. J. Physsiol. 267 (Heart Circ. Physiol. 36): H1962-H1967, 1994.
-
(1994)
Am. J. Physsiol.
, vol.267
-
-
Tesfamariam, B.1
-
149
-
-
0028568644
-
Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
-
Tsuga, H., K. Kameyama, T. Haga, H. Kurose, and T. Nagao. Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2. J. Biol. Chem. 269: 32522-32527, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32522-32527
-
-
Tsuga, H.1
Kameyama, K.2
Haga, T.3
Kurose, H.4
Nagao, T.5
-
150
-
-
0030463433
-
Mitogenic signaling via G protein-coupled receptors
-
Van Biesen, T., L. M. Luttrell, B. E. Hawes, and R. J. Lefkowitz. Mitogenic signaling via G protein-coupled receptors. Endocr. Rev. 17: 698-714, 1996.
-
(1996)
Endocr. Rev.
, vol.17
, pp. 698-714
-
-
Van Biesen, T.1
Luttrell, L.M.2
Hawes, B.E.3
Lefkowitz, R.J.4
-
151
-
-
0027411213
-
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts
-
Van Corven, E. J., P. L. Hordijk, R. H. Medema, J. L. Bos, and W. H. Moolenaar. Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts. Proc. Natl. Acad. Sci. USA 90: 1257-1261, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1257-1261
-
-
Van Corven, E.J.1
Hordijk, P.L.2
Medema, R.H.3
Bos, J.L.4
Moolenaar, W.H.5
-
152
-
-
0029012029
-
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
-
Vaughan, P. J., C. J. Pike, C. W. Cotman, and D. D. Cunningham. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J. Neurosci. 15: 5389-5401, 1995.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5389-5401
-
-
Vaughan, P.J.1
Pike, C.J.2
Cotman, C.W.3
Cunningham, D.D.4
-
153
-
-
0028566867
-
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease
-
Vaughan, P. J., J. Su, C. W. Cotman, and D. D. Cunningham. Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Res. 668: 160-170, 1994.
-
(1994)
Brain Res.
, vol.668
, pp. 160-170
-
-
Vaughan, P.J.1
Su, J.2
Cotman, C.W.3
Cunningham, D.D.4
-
154
-
-
0031002654
-
The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors
-
Verrall, S., M. Ishii, M. Chen, L. Wang, T. Tram, and S. R. Coughlin. The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors. J. Biol. Chem. 272: 6898-6902, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6898-6902
-
-
Verrall, S.1
Ishii, M.2
Chen, M.3
Wang, L.4
Tram, T.5
Coughlin, S.R.6
-
156
-
-
0028956090
-
Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor
-
Vouret-Craviari, V., D. Grail, J. C. Chambard, U. B. Rasmussen, J. Pouyssegur, and E. Van Obberghen-Schilling. Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor. J. Biol. Chem. 270: 8367-8372, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8367-8372
-
-
Vouret-Craviari, V.1
Grail, D.2
Chambard, J.C.3
Rasmussen, U.B.4
Pouyssegur, J.5
Van Obberghen-Schilling, E.6
-
157
-
-
0027497567
-
Differential activation of p44mapk (ERK1) by α-thrombin and thrombin-receptor peptide agonist
-
Vouret-Craviari, V., E. Van Obberghen-Schilling, J. C. Scimeca, E. Van Obberghen, and J. Pouyssegur. Differential activation of p44mapk (ERK1) by α-thrombin and thrombin-receptor peptide agonist. Biochem. J. 289: 209-214, 1993.
-
(1993)
Biochem. J.
, vol.289
, pp. 209-214
-
-
Vouret-Craviari, V.1
Van Obberghen-Schilling, E.2
Scimeca, J.C.3
Van Obberghen, E.4
Pouyssegur, J.5
-
158
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu, T. K., D. T. Hung, V. I. Wheaton, and S. R. Coughlin. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64: 1057-1068, 1991.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
159
-
-
0026072517
-
Domains specifying thrombin-receptor interaction
-
Vu, T. K., V. I. Wheaton, D. T. Hung, I. Charo, and S. R. Coughlin. Domains specifying thrombin-receptor interaction. Nature 353: 674-677, 1991.
-
(1991)
Nature
, vol.353
, pp. 674-677
-
-
Vu, T.K.1
Wheaton, V.I.2
Hung, D.T.3
Charo, I.4
Coughlin, S.R.5
-
160
-
-
0028914068
-
Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
-
Weinstein, J. R., S. J. Gold, D. D. Cunningham, and C. M. Gall. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J. Neurosci. 15: 2906-2919, 1995.
-
(1995)
J. Neurosci.
, vol.15
, pp. 2906-2919
-
-
Weinstein, J.R.1
Gold, S.J.2
Cunningham, D.D.3
Gall, C.M.4
-
162
-
-
0028933010
-
Induction of c-fos expression in rat vascular smooth muscle reporter cells by selective activation of the thrombin receptor
-
Yalkinoglu, A. O., P. Spreyer, M. Bechem, H. Apeler, and S. Wohlfeil. Induction of c-fos expression in rat vascular smooth muscle reporter cells by selective activation of the thrombin receptor. J. Recept. Signal Transduct. Res. 15: 117-130, 1995.
-
(1995)
J. Recept. Signal Transduct. Res.
, vol.15
, pp. 117-130
-
-
Yalkinoglu, A.O.1
Spreyer, P.2
Bechem, M.3
Apeler, H.4
Wohlfeil, S.5
-
163
-
-
0030936370
-
Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway
-
Yu, Z., S. Ahmad, J. L. Schwartz, D. Banville, and S. H. Shen. Protein-tyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway. J. Biol. Chem. 272: 7519-7524, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7519-7524
-
-
Yu, Z.1
Ahmad, S.2
Schwartz, J.L.3
Banville, D.4
Shen, S.H.5
-
164
-
-
0028900776
-
Thrombin, phorbol ester, and cAMP regulate thrombin receptor protein and mRNA expression by different pathways
-
Zacharias, U., Y. Xu, J. Hagege, J. D. Sraer, L. F. Brass, and E. Rondeau. Thrombin, phorbol ester, and cAMP regulate thrombin receptor protein and mRNA expression by different pathways. J. Biol. Chem. 270: 545-550, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 545-550
-
-
Zacharias, U.1
Xu, Y.2
Hagege, J.3
Sraer, J.D.4
Brass, L.F.5
Rondeau, E.6
-
165
-
-
0027374497
-
Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho
-
Zhang, J., W. G. King, S. Dillon, A. Hall, L. Feig, and S. E. Rittenhouse. Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho. J. Biol. Chem. 268: 22251-22254, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22251-22254
-
-
Zhang, J.1
King, W.G.2
Dillon, S.3
Hall, A.4
Feig, L.5
Rittenhouse, S.E.6
|