-
1
-
-
0036083491
-
Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats
-
Abete P., Testa G., Ferrara N., De Santis D., Capaccio P., Viati L., Calabrese C., Cacciatore F., Longobardi G., Condorelli M., et al. Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats. Am. J. Physiol. Heart Circ. Physiol. 282 (2002) H1978-H1987
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.282
-
-
Abete, P.1
Testa, G.2
Ferrara, N.3
De Santis, D.4
Capaccio, P.5
Viati, L.6
Calabrese, C.7
Cacciatore, F.8
Longobardi, G.9
Condorelli, M.10
-
2
-
-
0037166274
-
+ levels
-
+ levels. J. Biol. Chem. 277 (2002) 18881-18890
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18881-18890
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Cohen, H.5
Lin, S.S.6
Manchester, J.K.7
Gordon, J.I.8
Sinclair, D.A.9
-
3
-
-
0038329323
-
Nicotinamide and Pnc1 govern lifespan extension by calorie restriction in S. cerevisiae
-
Anderson R.M., Bitterman K.J., Wood J.G., Medvedik O., and Sinclair D.A. Nicotinamide and Pnc1 govern lifespan extension by calorie restriction in S. cerevisiae. Nature 423 (2003) 181-185
-
(2003)
Nature
, vol.423
, pp. 181-185
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Sinclair, D.A.5
-
4
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki T., Sasaki Y., and Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 (2004) 1010-1013
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
5
-
-
0036753953
-
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
-
Avalos J.L., Celic I., Muhammad S., Cosgrove M.S., Boeke J.D., and Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Mol. Cell 10 (2002) 523-535
-
(2002)
Mol. Cell
, vol.10
, pp. 523-535
-
-
Avalos, J.L.1
Celic, I.2
Muhammad, S.3
Cosgrove, M.S.4
Boeke, J.D.5
Wolberger, C.6
-
6
-
-
1642297558
-
Structural basis for the mechanism and regulation of Sir2 enzymes
-
Avalos J.L., Boeke J.D., and Wolberger C. Structural basis for the mechanism and regulation of Sir2 enzymes. Mol. Cell 13 (2004) 639-648
-
(2004)
Mol. Cell
, vol.13
, pp. 639-648
-
-
Avalos, J.L.1
Boeke, J.D.2
Wolberger, C.3
-
7
-
-
15244355745
-
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme
-
Avalos J.L., Bever K.M., and Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol. Cell 17 (2005) 855-868
-
(2005)
Mol. Cell
, vol.17
, pp. 855-868
-
-
Avalos, J.L.1
Bever, K.M.2
Wolberger, C.3
-
8
-
-
27744501798
-
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
-
Berger F., Lau C., Dahlmann M., and Ziegler M. Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J. Biol. Chem. 280 (2005) 36334-36341
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36334-36341
-
-
Berger, F.1
Lau, C.2
Dahlmann, M.3
Ziegler, M.4
-
9
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman K.J., Anderson R.M., Cohen H.Y., Latorre-Esteves M., and Sinclair D.A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277 (2002) 45099-45107
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
10
-
-
28844469898
-
Increase in activity during calorie restriction requires Sirt1
-
Chen D., Steele A.D., Lindquist S., and Guarente L. Increase in activity during calorie restriction requires Sirt1. Science 310 (2005) 1641
-
(2005)
Science
, vol.310
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
11
-
-
0842333189
-
Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma
-
Drevs J., Loser R., Rattel B., and Esser N. Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma. Anticancer Res. 23 (2003) 4853-4858
-
(2003)
Anticancer Res.
, vol.23
, pp. 4853-4858
-
-
Drevs, J.1
Loser, R.2
Rattel, B.3
Esser, N.4
-
12
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
Frye R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260 (1999) 273-279
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, pp. 273-279
-
-
Frye, R.A.1
-
13
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys. Res. Commun. 273 (2000) 793-798
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
14
-
-
13444262585
-
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin
-
Fukuhara A., Matsuda M., Nishizawa M., Segawa K., Tanaka M., Kishimoto K., Matsuki Y., Murakami M., Ichisaka T., Murakami H., et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science (2004)
-
(2004)
Science
-
-
Fukuhara, A.1
Matsuda, M.2
Nishizawa, M.3
Segawa, K.4
Tanaka, M.5
Kishimoto, K.6
Matsuki, Y.7
Murakami, M.8
Ichisaka, T.9
Murakami, H.10
-
15
-
-
5644265023
-
Signal transduction and functional changes in neutrophils with aging
-
Fulop T., Larbi A., Douziech N., Fortin C., Guerard K.P., Lesur O., Khalil A., and Dupuis G. Signal transduction and functional changes in neutrophils with aging. Aging Cell 3 (2004) 217-226
-
(2004)
Aging Cell
, vol.3
, pp. 217-226
-
-
Fulop, T.1
Larbi, A.2
Douziech, N.3
Fortin, C.4
Guerard, K.P.5
Lesur, O.6
Khalil, A.7
Dupuis, G.8
-
16
-
-
1642580758
-
Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity
-
Gallo C.M., Smith Jr. D.L., and Smith J.S. Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity. Mol. Cell Biol. 24 (2004) 1301-1312
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 1301-1312
-
-
Gallo, C.M.1
Smith Jr., D.L.2
Smith, J.S.3
-
17
-
-
13944253348
-
Calorie restriction - the SIR2 connection
-
Guarente L., and Picard F. Calorie restriction - the SIR2 connection. Cell 120 (2005) 473-482
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
18
-
-
1642276329
-
Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast
-
Halme A., Bumgarner S., Styles C., and Fink G.R. Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. Cell 116 (2004) 405-415
-
(2004)
Cell
, vol.116
, pp. 405-415
-
-
Halme, A.1
Bumgarner, S.2
Styles, C.3
Fink, G.R.4
-
19
-
-
3242659914
-
Effects of age and caloric restriction on brain neuronal cell death/survival
-
Hiona A., and Leeuwenburgh C. Effects of age and caloric restriction on brain neuronal cell death/survival. Ann. NY Acad. Sci. 1019 (2004) 96-105
-
(2004)
Ann. NY Acad. Sci.
, vol.1019
, pp. 96-105
-
-
Hiona, A.1
Leeuwenburgh, C.2
-
20
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz K.T., Bitterman K.J., Cohen H.Y., Lamming D.W., Lavu S., Wood J.G., Zipkin R.E., Chung P., Kisielewski A., Zhang L.L., et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425 (2003) 191-196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
-
21
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S., Armstrong C.M., Kaeberlein M., and Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000) 795-800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
22
-
-
85047693796
-
Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
-
Jia S.H., Li Y., Parodo J., Kapus A., Fan L., Rotstein O.D., and Marshall J.C. Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. J. Clin. Invest. 113 (2004) 1318-1327
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1318-1327
-
-
Jia, S.H.1
Li, Y.2
Parodo, J.3
Kapus, A.4
Fan, L.5
Rotstein, O.D.6
Marshall, J.C.7
-
24
-
-
22744452215
-
Food restriction, evolution and ageing
-
Kirkwood T.B., and Shanley D.P. Food restriction, evolution and ageing. Mech. Ageing Dev. 126 (2005) 1011-1016
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 1011-1016
-
-
Kirkwood, T.B.1
Shanley, D.P.2
-
25
-
-
0038356712
-
Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor
-
Kitani T., Okuno S., and Fujisawa H. Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor. FEBS Lett. 544 (2003) 74-78
-
(2003)
FEBS Lett.
, vol.544
, pp. 74-78
-
-
Kitani, T.1
Okuno, S.2
Fujisawa, H.3
-
26
-
-
24944559665
-
HST2 mediates SIR2-independent life-span extension by calorie restriction
-
Lamming D.W., Latorre-Esteves M., Medvedik O., Wong S.N., Tsang F.A., Wang C., Lin S.J., and Sinclair D.A. HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309 (2005) 1861-1864
-
(2005)
Science
, vol.309
, pp. 1861-1864
-
-
Lamming, D.W.1
Latorre-Esteves, M.2
Medvedik, O.3
Wong, S.N.4
Tsang, F.A.5
Wang, C.6
Lin, S.J.7
Sinclair, D.A.8
-
27
-
-
84871284357
-
HST2 mediates SIR2-independent life-span extension by calorie restriction
-
Lamming D.W., Latorre-Esteves M., Medvedik O., Wong S.N., Tsang F.A., Wang C., Lin S.J., and Sinclair D.A. HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 312 (2006) 1312
-
(2006)
Science
, vol.312
, pp. 1312
-
-
Lamming, D.W.1
Latorre-Esteves, M.2
Medvedik, O.3
Wong, S.N.4
Tsang, F.A.5
Wang, C.6
Lin, S.J.7
Sinclair, D.A.8
-
28
-
-
0034735990
-
Role of NAD(+) in the deacetylase activity of the SIR2-like proteins
-
Landry J., Slama J.T., and Sternglanz R. Role of NAD(+) in the deacetylase activity of the SIR2-like proteins. Biochem. Biophys. Res. Commun. 278 (2000) 685-690
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 685-690
-
-
Landry, J.1
Slama, J.T.2
Sternglanz, R.3
-
29
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
Landry J., Sutton A., Tafrov S.T., Heller R.C., Stebbins J., Pillus L., and Sternglanz R. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc. Natl. Acad. Sci. USA 97 (2000) 5807-5811
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
Sternglanz, R.7
-
30
-
-
31044435260
-
The role of the MAPK pathway alterations in GM-CSF modulated human neutrophil apoptosis with aging
-
Larbi A., Douziech N., Fortin C., Linteau A., Dupuis G., and Fulop Jr. T. The role of the MAPK pathway alterations in GM-CSF modulated human neutrophil apoptosis with aging. Immun. Ageing 2 (2005) 6
-
(2005)
Immun. Ageing
, vol.2
, pp. 6
-
-
Larbi, A.1
Douziech, N.2
Fortin, C.3
Linteau, A.4
Dupuis, G.5
Fulop Jr., T.6
-
31
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin S.J., Defossez P.A., and Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289 (2000) 2126-2128
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
32
-
-
0347128279
-
Calorie restriction extends yeast life span by lowering the level of NADH
-
Lin S.J., Ford E., Haigis M., Liszt G., and Guarente L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev. 18 (2004) 12-16
-
(2004)
Genes Dev.
, vol.18
, pp. 12-16
-
-
Lin, S.J.1
Ford, E.2
Haigis, M.3
Liszt, G.4
Guarente, L.5
-
33
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., and Gu W. Negative control of p53 by Sir2α promotes cell survival under stress. Cell 107 (2001) 137-148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
34
-
-
0035145516
-
Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence
-
Martin P.R., Shea R.J., and Mulks M.H. Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence. J. Bacteriol. 183 (2001) 1168-1174
-
(2001)
J. Bacteriol.
, vol.183
, pp. 1168-1174
-
-
Martin, P.R.1
Shea, R.J.2
Mulks, M.H.3
-
35
-
-
0034033586
-
Caloric restriction and aging: an update
-
Masoro E.J. Caloric restriction and aging: an update. Exp. Gerontol. 35 (2000) 299-305
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 299-305
-
-
Masoro, E.J.1
-
36
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
Min J., Landry J., Sternglanz R., and Xu R.M. Crystal structure of a SIR2 homolog-NAD complex. Cell 105 (2001) 269-279
-
(2001)
Cell
, vol.105
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.M.4
-
37
-
-
0042203536
-
Multiplex stress resistance in cells from long-lived dwarf mice
-
Murakami S., Salmon A., and Miller R.A. Multiplex stress resistance in cells from long-lived dwarf mice. FASEB J. 17 (2003) 1565-1566
-
(2003)
FASEB J.
, vol.17
, pp. 1565-1566
-
-
Murakami, S.1
Salmon, A.2
Miller, R.A.3
-
38
-
-
0033959206
-
Fetal membrane distention: I. Differentially expressed genes regulated by acute distention in amniotic epithelial (WISH) cells
-
Nemeth E., Tashima L.S., Yu Z., and Bryant-Greenwood G.D. Fetal membrane distention: I. Differentially expressed genes regulated by acute distention in amniotic epithelial (WISH) cells. Am. J. Obstet. Gynecol. 182 (2000) 50-59
-
(2000)
Am. J. Obstet. Gynecol.
, vol.182
, pp. 50-59
-
-
Nemeth, E.1
Tashima, L.S.2
Yu, Z.3
Bryant-Greenwood, G.D.4
-
39
-
-
0035062540
-
Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes
-
Ognjanovic S., Bao S., Yamamoto S.Y., Garibay-Tupas J., Samal B., and Bryant-Greenwood G.D. Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes. J. Mol. Endocrinol. 26 (2001) 107-117
-
(2001)
J. Mol. Endocrinol.
, vol.26
, pp. 107-117
-
-
Ognjanovic, S.1
Bao, S.2
Yamamoto, S.Y.3
Garibay-Tupas, J.4
Samal, B.5
Bryant-Greenwood, G.D.6
-
40
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
-
Picard F., Kurtev M., Chung N., Topark-Ngarm A., Senawong T., Machado De Oliveira R., Leid M., McBurney M.W., and Guarente L. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 429 (2004) 771-776
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
Machado De Oliveira, R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
42
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
Pruitt K., Zinn R.L., Ohm J.E., McGarvey K.M., Kang S.H., Watkins D.N., Herman J.G., and Baylin S.B. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2 (2006) e40
-
(2006)
PLoS Genet.
, vol.2
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
McGarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
Herman, J.G.7
Baylin, S.B.8
-
43
-
-
10944270187
-
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
-
Revollo J.R., Grimm A.A., and Imai S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J. Biol. Chem. 279 (2004) 50754-50763
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50754-50763
-
-
Revollo, J.R.1
Grimm, A.A.2
Imai, S.3
-
44
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B., and Helfand S.L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad Sci. USA 101 (2004) 15998-16003
-
(2004)
Proc. Natl. Acad Sci. USA
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
45
-
-
0036856578
-
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis
-
Rongvaux A., Shea R.J., Mulks M.H., Gigot D., Urbain J., Leo O., and Andris F. Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. Eur. J. Immunol. 32 (2002) 3225-3234
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3225-3234
-
-
Rongvaux, A.1
Shea, R.J.2
Mulks, M.H.3
Gigot, D.4
Urbain, J.5
Leo, O.6
Andris, F.7
-
46
-
-
0027958452
-
Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor
-
Samal B., Sun Y., Stearns G., Xie C., Suggs S., and McNiece I. Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Mol. Cell Biol. 14 (1994) 1431-1437
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 1431-1437
-
-
Samal, B.1
Sun, Y.2
Stearns, G.3
Xie, C.4
Suggs, S.5
McNiece, I.6
-
47
-
-
0041571570
-
Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry
-
Sauve A.A., and Schramm V.L. Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. Biochemistry 42 (2003) 9249-9256
-
(2003)
Biochemistry
, vol.42
, pp. 9249-9256
-
-
Sauve, A.A.1
Schramm, V.L.2
-
49
-
-
4544243684
-
Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation
-
Schmidt M.T., Smith B.C., Jackson M.D., and Denu J.M. Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation. J. Biol. Chem. 279 (2004) 40122-40129
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40122-40129
-
-
Schmidt, M.T.1
Smith, B.C.2
Jackson, M.D.3
Denu, J.M.4
-
50
-
-
22744450382
-
Toward a unified theory of caloric restriction and longevity regulation
-
Sinclair D.A. Toward a unified theory of caloric restriction and longevity regulation. Mech. Ageing Dev (2005)
-
(2005)
Mech. Ageing Dev
-
-
Sinclair, D.A.1
-
51
-
-
12944283150
-
+-dependent protein deacetylase activity in the Sir2 protein family
-
+-dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA 97 (2000) 6658-6663
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6658-6663
-
-
Smith, J.S.1
Brachmann, C.B.2
Celic, I.3
Kenna, M.A.4
Muhammad, S.5
Starai, V.J.6
Avalos, J.L.7
Escalante-Semerena, J.C.8
Grubmeyer, C.9
Wolberger, C.10
Boeke, J.D.11
-
52
-
-
0023081730
-
Biophysical chemistry of metabolic reaction sequences in concentrated enzyme solution and in the cell
-
Srivastava D.K., and Bernhard S.A. Biophysical chemistry of metabolic reaction sequences in concentrated enzyme solution and in the cell. Annu. Rev. Biophys. Biophys. Chem. 16 (1987) 175-204
-
(1987)
Annu. Rev. Biophys. Biophys. Chem.
, vol.16
, pp. 175-204
-
-
Srivastava, D.K.1
Bernhard, S.A.2
-
53
-
-
0034687694
-
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
Tanner K.G., Landry J., Sternglanz R., and Denu J.M. Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc. Natl. Acad. Sci. USA 97 (2000) 14178-14182
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landry, J.2
Sternglanz, R.3
Denu, J.M.4
-
54
-
-
0033598942
-
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
-
Tanny J.C., Dowd G.J., Huang J., Hilz H., and Moazed D. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99 (1999) 735-745
-
(1999)
Cell
, vol.99
, pp. 735-745
-
-
Tanny, J.C.1
Dowd, G.J.2
Huang, J.3
Hilz, H.4
Moazed, D.5
-
55
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum H.A., and Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001) 227-230
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
56
-
-
0033610894
-
CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2
-
Tsang A.W., and Escalante-Semerena J.C. CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2. J. Biol. Chem. 273 (1998) 31788-31794
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31788-31794
-
-
Tsang, A.W.1
Escalante-Semerena, J.C.2
-
57
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
Vaquero A., Scher M., Lee D., Erdjument-Bromage H., Tempst P., and Reinberg D. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell 16 (2004) 93-105
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
58
-
-
0035913903
-
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Eaton E.N., Imai S.I., Frye R.A., Pandita T.K., Guarente L., and Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107 (2001) 149-159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
59
-
-
0037151779
-
Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death
-
Vergnes B., Sereno D., Madjidian-Sereno N., Lemesre J.L., and Ouaissi A. Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death. Gene 296 (2002) 139-150
-
(2002)
Gene
, vol.296
, pp. 139-150
-
-
Vergnes, B.1
Sereno, D.2
Madjidian-Sereno, N.3
Lemesre, J.L.4
Ouaissi, A.5
-
60
-
-
28244475950
-
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO
-
Wang Y., and Tissenbaum H.A. Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. Mech. Ageing Dev. 127 (2006) 48-56
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 48-56
-
-
Wang, Y.1
Tissenbaum, H.A.2
-
61
-
-
20144386977
-
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
-
Wang J., Ho L., Qin W., Rocher A.B., Seror I., Humala N., Maniar K., Dolios G., Wang R., Hof P.R., and Pasinetti G.M. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J (2005)
-
(2005)
FASEB J
-
-
Wang, J.1
Ho, L.2
Qin, W.3
Rocher, A.B.4
Seror, I.5
Humala, N.6
Maniar, K.7
Dolios, G.8
Wang, R.9
Hof, P.R.10
Pasinetti, G.M.11
-
62
-
-
0036697292
-
Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1
-
Xu L.G., Wu M., Hu J., Zhai Z., and Shu H.B. Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1. J. Leukoc. Biol. 72 (2002) 410-416
-
(2002)
J. Leukoc. Biol.
, vol.72
, pp. 410-416
-
-
Xu, L.G.1
Wu, M.2
Hu, J.3
Zhai, Z.4
Shu, H.B.5
-
63
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., and Mayo M.W. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23 (2004) 2369-2380
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
64
-
-
1542298916
-
Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli
-
Zhao K., Chai X., and Marmorstein R. Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli. J. Mol. Biol. 337 (2004) 731-741
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 731-741
-
-
Zhao, K.1
Chai, X.2
Marmorstein, R.3
-
65
-
-
2942534101
-
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases
-
Zhao K., Harshaw R., Chai X., and Marmorstein R. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc. Natl. Acad. Sci. USA 101 (2004) 8563-8568
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8563-8568
-
-
Zhao, K.1
Harshaw, R.2
Chai, X.3
Marmorstein, R.4
|