Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast

Cell

Volumn 116, Issue 3, 2004, Pages 405-415

  Halme, Adrian ^a,b   Bumgarner, Stacie ^a,b   Styles, Cora ^a   Fink, Gerald R ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE PROTEIN; GLYCOPROTEIN; HISTONE DEACETYLASE; REGULATOR PROTEIN;

ARTICLE; CELL CLONE; CELL POPULATION; CELL SURFACE; CONTROLLED STUDY; DIPLOIDY; ENZYME REGULATION; EPIGENETICS; FLO GENE; FUNGAL GENE; FUNGUS HYPHAE; GENE EXPRESSION REGULATION; GENE SILENCING; GENE SWITCHING; GENETIC VARIABILITY; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST;

FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 1642276329     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00118-7     Document Type: Article

References (51)

1. Bernards A., Van der Ploeg L.H., Frasch A.C., Borst P., Boothroyd J.C., Coleman S., Cross G.A. Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end. Cell. 27:1981;497-505.
2. Brachmann C.B., Sherman J.M., Devine S.E., Cameron E.E., Pillus L., Boeke J.D. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev. 9:1995;2888-2902.
3. Brandriss M.C., Magasanik B. Genetics and physiology of proline utilization in Saccharomyces cerevisiae. mutation causing constitutive enzyme expression J. Bacteriol. 140:1979;504-507.
4. Braun B.R., Johnson A.D. Control of filament formation in Candida albicans by the transcriptional repressor TUP1. Science. 277:1997;105-109.
5. Conlan R.S., Tzamarias D. Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2. J. Mol. Biol. 309:2001;1007-1015.
6. Cormack B.P., Ghori N., Falkow S. An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells. Science. 285:1999;578-582.
7. De Las Penas A., Pan S.J., Castano I., Alder J., Cregg R., Cormack B.P. Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing. Genes Dev. 17:2003;2245-2258.
8. Gagiano M., van Dyk D., Bauer F.F., Lambrechts M.G., Pretorius I.S. Msn1p/Mss10p, Mss11p and Muc1p/Flo11p are part of a signal transduction pathway downstream of Mep2p regulating invasive growth and pseudohyphal differentiation in Saccharomyces cerevisiae. Mol. Microbiol. 31:1999;103-116.
9. Gimeno C.J., Ljungdahl P.O., Styles C.A., Fink G.R. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth. regulation by starvation and RAS Cell. 68:1992;1077-1090.
10. Gottschling D.E., Aparicio O.M., Billington B.L., Zakian V.A. Position effect at S. cerevisiae telomeres. reversible repression of Pol II transcription Cell. 63:1990;751-762.
11. Grenson M., Mousset M., Wiame J.M., Bechet J. Multiplicity of the amino acid permeases in Saccharomyces cerevisiae. I. Evidence for a specific arginine-transporting system. Biochim. Biophys. Acta. 127:1966;325-338.
12. Guo B., Styles C.A., Feng Q., Fink G.R. A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Proc. Natl. Acad. Sci. USA. 97:2000;12158-12163.
13. Haber J.E., George J.P. Mutation that permits the expression of normally silent copies of mating-type information in Saccharomyces cerevisiae. Genetics. 93:1979;13-35.
14. Heim R., Prasher D.C., Tsien R.Y. Wavelength mutations and posttranslational autoxidation of green fluorescent protein. Proc. Natl. Acad. Sci. USA. 91:1994;12501-12504.
15. Howell-Adams B., Seifert H.S. Molecular models accounting for the gene conversion reactions mediating gonococcal pilin antigenic variation. Mol. Microbiol. 37:2000;1146-1158.
16. Hoyer L.L. The ALS gene family of Candida albicans. Trends Microbiol. 9:2001;176-180.
17. Jiang Y.W., Stillman D.J. Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus. Genes Dev. 10:1996;604-619.
18. Kennedy B.K., Gotta M., Sinclair D.A., Mills K., McNabb D.S., Murthy M., Pak S.M., Laroche T., Gasser S.M., Guarente L. Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell. 89:1997;381-391.
19. Knop M., Siegers K., Pereira G., Zachariae W., Winsor B., Nasmyth K., Schiebel E. Epitope tagging of yeast genes using a PCR-based strategy. more tags and improved practical routines Yeast. 15:1999;963-972.
20. Kumar A., Vidan S., Snyder M. Insertional mutagenesis. transposon-insertion libraries as mutagens in yeast Methods Enzymol. 350:2002;219-229.
21. Lo W.S., Dranginis A.M. The cell surface flocculin Flo11 is required for pseudohyphae formation and invasion by Saccharomyces cerevisiae. Mol. Biol. Cell. 9:1998;161-171.
22. Lo H.J., Kohler J.R., DiDomenico B., Loebenberg D., Cacciapuoti A., Fink G.R. Nonfilamentous C. albicans mutants are avirulent. Cell. 90:1997;939-949.
23. Martin S.G., Laroche T., Suka N., Grunstein M., Gasser S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell. 97:1999;621-633.
24. Mehr I.J., Seifert H.S. Differential roles of homologous recombination pathways in Neisseria gonorrhoeae pilin antigenic variation, DNA transformation and DNA repair. Mol. Microbiol. 30:1998;697-710.
25. Michels P.A., Van der Ploeg L.H., Liu A.Y., Borst P. The inactivation and reactivation of an expression-linked gene copy for a variant surface glycoprotein in Trypanosoma brucei. EMBO J. 3:1984;1345-1351.
26. Mishra K., Shore D. Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr. Biol. 9:1999;1123-1126.
27. Moazed D., Kistler A., Axelrod A., Rine J., Johnson A.D. Silent information regulator protein complexes in Saccharomyces cerevisiae. a SIR2/ SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3 Proc. Natl. Acad. Sci. USA. 94:1997;2186-2191.
28. Moretti P., Freeman K., Coodly L., Shore D. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8:1994;2257-2269.
29. Otto S.P., Yong P. The evolution of gene duplicates. Adv. Genet. 46:2002;451-483.
30. Pan X., Heitman J. Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. Mol. Cell. Biol. 22:2002;3981-3993.
31. Pays E., Delauw M.F., Van Assel S., Laurent M., Vervoort T., Van Meirvenne N., Steinert M. Modifications of a Trypanosoma b. brucei antigen gene repertoire by different DNA recombinational mechanisms. Cell. 35:1983;721-731. a.
32. Pays E., Van Assel S., Laurent M., Darville M., Vervoort T., Van Meirvenne N., Steinert M. Gene conversion as a mechanism for antigenic variation in trypanosomes. Cell. 34:1983;371-381. b.
33. Pays E., Vanhamme L., Berberof M. Genetic controls for the expression of surface antigens in African trypanosomes. Annu. Rev. Microbiol. 48:1994;25-52.
34. Reynolds T.B., Fink G.R. Bakers' yeast, a model for fungal biofilm formation. Science. 291:2001;878-881.
35. Rine J., Herskowitz I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics. 116:1987;9-22.
36. Rine J., Strathern J.N., Hicks J.B., Herskowitz I. A suppressor of mating-type locus mutations in Saccharomyces cerevisiae. evidence for and identification of cryptic mating-type loci Genetics. 93:1979;877-901.
37. Robertson L.S., Fink G.R. The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proc. Natl. Acad. Sci. USA. 95:1998;13783-13787.
38. Robyr D., Suka Y., Xenarios I., Kurdistani S.K., Wang A., Suka N., Grunstein M. Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell. 109:2002;437-446.
39. Rose M.D., Winston F., Hieter P. Methods in Yeast Genetics. A Laboratory Course Manual:1990;Cold Spring Horbor Laboratory Press, Cold Spring Harbor, New York.
40. Rudenko G., Blundell P.A., Dirks-Mulder A., Kieft R., Borst P. A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei. Cell. 83:1995;547-553.
41. Rupp S., Summers E., Lo H.J., Madhani H., Fink G. MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene. EMBO J. 18:1999;1257-1269.
42. Russell M., Bradshaw-Rouse J., Markwardt D., Heideman W. Changes in gene expression in the Ras/adenylate cyclase system of Saccharomyces cerevisiae. correlation with cAMP levels and growth arrest Mol. Biol. Cell. 4:1993;757-765.
43. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning a Laboratory Manual, second edition. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
44. Saville S.P., Lazzell A.L., Monteagudo C., Lopez-Ribot J.L. Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous frms of Candida albicans during infection. Eukaryot. Cell. 2:2003;1053-1060.
45. Siddiqui A.H., Brandriss M.C. A regulatory region responsible for proline-specific induction of the yeast PUT2 gene is adjacent to its TATA box. Mol. Cell. Biol. 8:1988;4634-4641.
46. Smith J.S., Boeke J.D. An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11:1997;241-254.
47. Stringer J.R., Keely S.P. Genetics of surface antigen expression in Pneumocystis carinii. Infect. Immun. 69:2001;627-639.
48. Tanaka K., Nakafuku M., Tamanoi F., Kaziro Y., Matsumoto K., Toh-e A. IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol. Cell. Biol. 10:1990;4303-4313.
49. Weiden M., Osheim Y.N., Beyer A.L., Van der Ploeg L.H. Chromosome structure. DNA nucleotide sequence elements of a subset of the minichromosomes of the protozoan Trypanosoma brucei Mol. Cell. Biol. 11:1991;3823-3834.
50. Wu J., Suka N., Carlson M., Grunstein M. TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast. Mol. Cell. 7:2001;117-126.
51. Wyrick J.J., Holstege F.C., Jennings E.G., Causton H.C., Shore D., Grunstein M., Lander E.S., Young R.A. Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature. 402:1999;418-421.