메뉴 건너뛰기




Volumn 2006, Issue , 2006, Pages

Essential notes regarding the design of functional siRNAs for efficient mammalian RNAi

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OLIGOMER; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 33746840096     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/JBB/2006/65052     Document Type: Review
Times cited : (12)

References (98)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
    • A Fire S Xu M K Montgomery S A Kostas S E Driver C C Mello Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 391 6669 1998 806 811
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 3
    • 4644336023 scopus 로고    scopus 로고
    • Revealing the world of RNA interference
    • C C Mello D Jr Conte Revealing the world of RNA interference. Nature 431 7006 2004 338 342
    • (2004) Nature , vol.431 , Issue.7006 , pp. 338-342
    • Mello, C.C.1    Conte Jr., D.2
  • 4
    • 4644223259 scopus 로고    scopus 로고
    • Mechanisms of gene silencing by double-stranded RNA
    • G Meister T Tuschl Mechanisms of gene silencing by double-stranded RNA. Nature 431 7006 2004 343 349
    • (2004) Nature , vol.431 , Issue.7006 , pp. 343-349
    • Meister, G.1    Tuschl, T.2
  • 5
    • 33645148088 scopus 로고    scopus 로고
    • The silent treatment: SiRNAs as small molecule drugs
    • D M Dykxhoorn D Palliser J Lieberman The silent treatment: siRNAs as small molecule drugs. Gene Therapy 13 6 2006 541 552
    • (2006) Gene Therapy , vol.13 , Issue.6 , pp. 541-552
    • Dykxhoorn, D.M.1    Palliser, D.2    Lieberman, J.3
  • 6
    • 0034683099 scopus 로고    scopus 로고
    • Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
    • K Ui-Tei S Zenno Y Miyata K Saigo Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Letters 479 3 2000 79 82
    • (2000) FEBS Letters , vol.479 , Issue.3 , pp. 79-82
    • Ui-Tei, K.1    Zenno, S.2    Miyata, Y.3    Saigo, K.4
  • 8
    • 0035128859 scopus 로고    scopus 로고
    • Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi
    • I Maeda Y Kohara M Yamamoto A Sugimoto Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Current Biology 11 3 2001 171 176
    • (2001) Current Biology , vol.11 , Issue.3 , pp. 171-176
    • Maeda, I.1    Kohara, Y.2    Yamamoto, M.3    Sugimoto, A.4
  • 9
    • 0035738661 scopus 로고    scopus 로고
    • RNAi: A new technology in the post-genomic sequencing era
    • R Ueda RNAi: a new technology in the post-genomic sequencing era. Journal of Neurogenetics 15 3-4 2001 193 204
    • (2001) Journal of Neurogenetics , vol.15 , Issue.3-4 , pp. 193-204
    • Ueda, R.1
  • 10
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • K Ashrafi F Y Chang J L Watts Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421 6920 2003 268 272
    • (2003) Nature , vol.421 , Issue.6920 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3
  • 11
    • 0842309871 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of growth and viability in Drosophila cells
    • M Boutros A A Kiger S Armknecht Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303 5659 2004 832 835
    • (2004) Science , vol.303 , Issue.5659 , pp. 832-835
    • Boutros, M.1    Kiger, A.A.2    Armknecht, S.3
  • 12
    • 0346728473 scopus 로고    scopus 로고
    • Systematic genome-wide screens of gene function. Nature Reviews
    • A E Carpenter D M Sabatini Systematic genome-wide screens of gene function. Nature Reviews. Genetics 5 1 2004 11 22
    • (2004) Genetics , vol.5 , Issue.1 , pp. 11-22
    • Carpenter, A.E.1    Sabatini, D.M.2
  • 14
    • 28444451148 scopus 로고    scopus 로고
    • A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway
    • K Nybakken S A Vokes T-Y Lin A P McMahon N Perrimon A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nature Genetics 37 12 2005 1323 1332
    • (2005) Nature Genetics , vol.37 , Issue.12 , pp. 1323-1332
    • Nybakken, K.1    Vokes, S.A.2    Lin, T.-Y.3    McMahon, A.P.4    Perrimon, N.5
  • 15
    • 21044446786 scopus 로고    scopus 로고
    • Functional genomic analysis of RNA interference in C. elegans
    • J K Kim H W Gabel R S Kamath Functional genomic analysis of RNA interference in C. elegans. Science 308 5725 2005 1164 1167
    • (2005) Science , vol.308 , Issue.5725 , pp. 1164-1167
    • Kim, J.K.1    Gabel, H.W.2    Kamath, R.S.3
  • 17
    • 5444236205 scopus 로고    scopus 로고
    • Challenges and strategies: The immune responses in gene therapy
    • H-S Zhou D-P Liu C-C Liang Challenges and strategies: the immune responses in gene therapy. Medicinal Research Reviews 24 6 2004 748 761
    • (2004) Medicinal Research Reviews , vol.24 , Issue.6 , pp. 748-761
    • Zhou, H.-S.1    Liu, D.-P.2    Liang, C.-C.3
  • 18
    • 20444395838 scopus 로고    scopus 로고
    • Immune responses to dsRNA: Implications for gene silencing technologies
    • A J Karpala T J Doran A GD Bean Immune responses to dsRNA: implications for gene silencing technologies. Immunology and Cell Biology 83 3 2005 211 216
    • (2005) Immunology and Cell Biology , vol.83 , Issue.3 , pp. 211-216
    • Karpala, A.J.1    Doran, T.J.2    Bean, A.G.D.3
  • 20
    • 27944459341 scopus 로고    scopus 로고
    • Activation of the mammalian immune system by siRNAs
    • J T Marques B RG Williams Activation of the mammalian immune system by siRNAs. Nature Biotechnology 23 11 2005 1399 1405
    • (2005) Nature Biotechnology , vol.23 , Issue.11 , pp. 1399-1405
    • Marques, J.T.1    Williams, B.R.G.2
  • 21
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • S M Elbashir W Lendeckel T Tuschl RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes and Development 15 2 2001 188 200
    • (2001) Genes and Development , vol.15 , Issue.2 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 22
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • S M Elbashir J Harborth W Lendeckel A Yalcin K Weber T Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 6836 2001 494 498
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 23
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • S M Elbashir J Martinez A Patkaniowska W Lendeckel T Tuschl Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO Journal 20 23 2001 6877 6888
    • (2001) EMBO Journal , vol.20 , Issue.23 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 25
    • 18044365415 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    • M Sioud Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization. Journal of Molecular Biology 348 5 2005 1079 1090
    • (2005) Journal of Molecular Biology , vol.348 , Issue.5 , pp. 1079-1090
    • Sioud, M.1
  • 26
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
    • V Hornung M Guenthner-Biller C Bourquin Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nature Medicine 11 3 2005 263 270
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 263-270
    • Hornung, V.1    Guenthner-Biller, M.2    Bourquin, C.3
  • 28
    • 33746842419 scopus 로고    scopus 로고
    • RNAi induced in mammalian and Drosophila cells via transfection of dimers and trimers of short interfering RNA
    • K Ui-Tei S Zenno A Juni K Saigo RNAi induced in mammalian and Drosophila cells via transfection of dimers and trimers of short interfering RNA. Journal of RNAi and Gene Silencing 1 2005 2 79 87
    • (2005) Journal of RNAi and Gene Silencing , vol.1 , Issue.2 , pp. 79-87
    • Ui-Tei, K.1    Zenno, S.2    Juni, A.3    Saigo, K.4
  • 29
    • 1642346273 scopus 로고    scopus 로고
    • Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
    • K Ui-Tei Y Naito F Takahashi Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Research 32 3 2004 936 948
    • (2004) Nucleic Acids Research , vol.32 , Issue.3 , pp. 936-948
    • Ui-Tei, K.1    Naito, Y.2    Takahashi, F.3
  • 30
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
    • T Holen M Amarzguioui M T Wiiger E Babaie H Prydz Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Research 30 8 2002 1757 1766
    • (2002) Nucleic Acids Research , vol.30 , Issue.8 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 31
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • A L Jackson S R Bartz J Schelter Expression profiling reveals off-target gene regulation by RNAi. Nature Biotechnology 21 6 2003 635 637
    • (2003) Nature Biotechnology , vol.21 , Issue.6 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 32
    • 4744373229 scopus 로고    scopus 로고
    • Noise amidst the silence: Off-target effects of siRNAs?
    • A L Jackson P S Linsley Noise amidst the silence: off-target effects of siRNAs? Trends in Genetics 20 11 2004 521 524
    • (2004) Trends in Genetics , vol.20 , Issue.11 , pp. 521-524
    • Jackson, A.L.1    Linsley, P.S.2
  • 33
    • 15044358407 scopus 로고    scopus 로고
    • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    • Q Du H Thonberg J Wang C Wahlestedt Z Liang A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research 33 5 2005 1671 1677
    • (2005) Nucleic Acids Research , vol.33 , Issue.5 , pp. 1671-1677
    • Du, Q.1    Thonberg, H.2    Wang, J.3    Wahlestedt, C.4    Liang, Z.5
  • 34
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • J Martinez A Patkaniowska H Urlaub R Lührmann T Tuschl Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 5 2002 563 574
    • (2002) Cell , vol.110 , Issue.5 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Lührmann, R.4    Tuschl, T.5
  • 35
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • J-J Song S K Smith G J Hannon L Joshua-Tor Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305 5689 2004 1434 1437
    • (2004) Science , vol.305 , Issue.5689 , pp. 1434-1437
    • Song, J.-J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 36
    • 4444368187 scopus 로고    scopus 로고
    • Argonaute2 is the catalytic engine of mammalian RNAi
    • J Liu M A Carmell F V Rivas Argonaute2 is the catalytic engine of mammalian RNAi. Science 305 5689 2004 1437 1441
    • (2004) Science , vol.305 , Issue.5689 , pp. 1437-1441
    • Liu, J.1    Carmell, M.A.2    Rivas, F.V.3
  • 37
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
    • J S Parker S M Roe D Barford Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 434 7033 2005 663 666
    • (2005) Nature , vol.434 , Issue.7033 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 38
    • 28444437427 scopus 로고    scopus 로고
    • Slicer function of Drosophila Argonautes and its involvement in RISC formation
    • K Miyoshi H Tsukumo T Nagami H Siomi M C Siomi Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes and Development 19 23 2005 2837 2848
    • (2005) Genes and Development , vol.19 , Issue.23 , pp. 2837-2848
    • Miyoshi, K.1    Tsukumo, H.2    Nagami, T.3    Siomi, H.4    Siomi, M.C.5
  • 39
    • 0141886425 scopus 로고    scopus 로고
    • Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference
    • A Abdelgany M Wood D Beeson Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference. Human Molecular Genetics 12 20 2003 2637 2644
    • (2003) Human Molecular Genetics , vol.12 , Issue.20 , pp. 2637-2644
    • Abdelgany, A.1    Wood, M.2    Beeson, D.3
  • 40
    • 3242889236 scopus 로고    scopus 로고
    • SiDirect: Highly effective, target-specific siRNA design software for mammalian RNA interference
    • Y Naito T Yamada K Ui-Tei S Morishita K Saigo siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference. Nucleic Acids Research 32 2004 W124 W129
    • (2004) Nucleic Acids Research , vol.32
    • Naito, Y.1    Yamada, T.2    Ui-Tei, K.3    Morishita, S.4    Saigo, K.5
  • 41
    • 17444383131 scopus 로고    scopus 로고
    • Accelerated off-target search algorithm for siRNA
    • T Yamada S Morishita Accelerated off-target search algorithm for siRNA. Bioinformatics 21 8 2005 1316 1324
    • (2005) Bioinformatics , vol.21 , Issue.8 , pp. 1316-1324
    • Yamada, T.1    Morishita, S.2
  • 43
    • 11844270487 scopus 로고    scopus 로고
    • Mechanistic insights aid computational short interfering RNA design
    • Q Boese D Leake A Reynolds Mechanistic insights aid computational short interfering RNA design. Methods in Enzymology 392 2005 73 96
    • (2005) Methods in Enzymology , vol.392 , pp. 73-96
    • Boese, Q.1    Leake, D.2    Reynolds, A.3
  • 44
    • 17844387370 scopus 로고    scopus 로고
    • A computational study of off-target effects of RNA interference
    • S Qiu C M Adema T Lane A computational study of off-target effects of RNA interference. Nucleic Acids Research 33 6 2005 1834 1847
    • (2005) Nucleic Acids Research , vol.33 , Issue.6 , pp. 1834-1847
    • Qiu, S.1    Adema, C.M.2    Lane, T.3
  • 45
    • 23144436831 scopus 로고    scopus 로고
    • DsCheck: Highly sensitive off-target search software for double-stranded RNA-mediated RNA interference
    • Y Naito T Yamada T Matsumiya K Ui-Tei K Saigo S Morishita dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference. Nucleic Acids Research 33 2005 suppl 2 W589 W591
    • (2005) Nucleic Acids Research , vol.33 , Issue.2
    • Naito, Y.1    Yamada, T.2    Matsumiya, T.3    Ui-Tei, K.4    Saigo, K.5    Morishita, S.6
  • 46
    • 3242891277 scopus 로고    scopus 로고
    • DEQOR: A web-based tool for the design and quality control of siRNAs
    • A Henschel F Buchholz B Habermann DEQOR: a web-based tool for the design and quality control of siRNAs. Nucleic Acids Research 32 2004 W113 W120
    • (2004) Nucleic Acids Research , vol.32
    • Henschel, A.1    Buchholz, F.2    Habermann, B.3
  • 47
  • 49
    • 3242877996 scopus 로고    scopus 로고
    • Sfold web server for statistical folding and rational design of nucleic acids
    • Y Ding C Y Chan C E Lawrence Sfold web server for statistical folding and rational design of nucleic acids. Nucleic Acids Research 32 2004 W135 W141
    • (2004) Nucleic Acids Research , vol.32
    • Ding, Y.1    Chan, C.Y.2    Lawrence, C.E.3
  • 50
    • 17444368334 scopus 로고    scopus 로고
    • Highly specific and accurate selection of siRNAs for high-throughput functional assays
    • J Santoyo J M Vaquerizas J Dopazo Highly specific and accurate selection of siRNAs for high-throughput functional assays. Bioinformatics 21 8 2005 1376 1382
    • (2005) Bioinformatics , vol.21 , Issue.8 , pp. 1376-1382
    • Santoyo, J.1    Vaquerizas, J.M.2    Dopazo, J.3
  • 51
    • 13444282536 scopus 로고    scopus 로고
    • Filtering of ineffective siRNAs and improved siRNA design tool
    • S M Yiu P WH Wong T W Lam Filtering of ineffective siRNAs and improved siRNA design tool. Bioinformatics 21 2 2005 144 151
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 144-151
    • Yiu, S.M.1    Wong, P.W.H.2    Lam, T.W.3
  • 53
    • 4444264981 scopus 로고    scopus 로고
    • A web-based design center for vector-based siRNA and siRNA cassette
    • L Wang F Y Mu A web-based design center for vector-based siRNA and siRNA cassette. Bioinformatics 20 11 2004 1818 1820
    • (2004) Bioinformatics , vol.20 , Issue.11 , pp. 1818-1820
    • Wang, L.1    Mu, F.Y.2
  • 55
    • 36549012190 scopus 로고    scopus 로고
    • Guidelines for selection of effective short-interfering RNA sequences for functional genomics
    • K Ui-Tei Y Naito K Saigo Guidelines for selection of effective short-interfering RNA sequences for functional genomics. Methods in Molecular Biology 2 2006 201 216
    • (2006) Methods in Molecular Biology , vol.2 , pp. 201-216
    • Ui-Tei, K.1    Naito, Y.2    Saigo, K.3
  • 57
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • A Khvorova A Reynolds S D Jayasena Functional siRNAs and miRNAs exhibit strand bias. Cell 115 2 2003 209 216
    • (2003) Cell , vol.115 , Issue.2 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 58
    • 2542607603 scopus 로고    scopus 로고
    • Efficient RNA interference depends on global context of the target sequence: Quantitative analysis of silencing efficiency using Eulerian graph representation of siRNA
    • P Pancoska Z Moravek U M Moll Efficient RNA interference depends on global context of the target sequence: quantitative analysis of silencing efficiency using Eulerian graph representation of siRNA. Nucleic Acids Research 32 4 2004 1469 1479
    • (2004) Nucleic Acids Research , vol.32 , Issue.4 , pp. 1469-1479
    • Pancoska, P.1    Moravek, Z.2    Moll, U.M.3
  • 61
    • 21844471799 scopus 로고    scopus 로고
    • Sequence characteristics of functional siRNAs
    • B Jagla N Aulner P D Kelly Sequence characteristics of functional siRNAs. RNA 11 6 2005 864 872
    • (2005) RNA , vol.11 , Issue.6 , pp. 864-872
    • Jagla, B.1    Aulner, N.2    Kelly, P.D.3
  • 63
    • 0019887799 scopus 로고
    • Identification of common molecular subsequences
    • T F Smith M S Waterman Identification of common molecular subsequences. Journal of Molecular Biology 147 1 1981 195 197
    • (1981) Journal of Molecular Biology , vol.147 , Issue.1 , pp. 195-197
    • Smith, T.F.1    Waterman, M.S.2
  • 65
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • M Lagos-Quintana R Rauhut W Lendeckel T Tuschl Identification of novel genes coding for small expressed RNAs. Science 294 5543 2001 853 858
    • (2001) Science , vol.294 , Issue.5543 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 66
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • V Ambros microRNAs: tiny regulators with great potential. Cell 107 7 2001 823 826
    • (2001) Cell , vol.107 , Issue.7 , pp. 823-826
    • Ambros, V.1
  • 67
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • M T McManus P A Sharp Gene silencing in mammals by small interfering RNAs. Nature Reviews Genetics 3 10 2002 737 747
    • (2002) Nature Reviews Genetics , vol.3 , Issue.10 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 68
    • 0037370020 scopus 로고    scopus 로고
    • A uniform system for microRNA annotation
    • V Ambros B Bartel D P Bartel A uniform system for microRNA annotation. RNA 9 3 2003 277 279
    • (2003) RNA , vol.9 , Issue.3 , pp. 277-279
    • Ambros, V.1    Bartel, B.2    Bartel, D.P.3
  • 69
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • L He G J Hannon MicroRNAs: small RNAs with a big role in gene regulation. Nature Reviews Genetics 5 7 2004 522 531
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 70
    • 22144461002 scopus 로고    scopus 로고
    • MiRNAs, cancer, and stem cell division
    • C M Croce G A Calin miRNAs, cancer, and stem cell division. Cell 122 1 2005 6 7
    • (2005) Cell , vol.122 , Issue.1 , pp. 6-7
    • Croce, C.M.1    Calin, G.A.2
  • 71
    • 22144437679 scopus 로고    scopus 로고
    • Silence from within: Endogenous siRNAs and miRNAs
    • E J Sontheimer R W Carthew Silence from within: endogenous siRNAs and miRNAs. Cell 122 1 2005 9 12
    • (2005) Cell , vol.122 , Issue.1 , pp. 9-12
    • Sontheimer, E.J.1    Carthew, R.W.2
  • 72
    • 25844528520 scopus 로고    scopus 로고
    • MicroRNAs and viral infection
    • C S Sullivan D Ganem MicroRNAs and viral infection. Molecular Cell 20 1 2005 3 7
    • (2005) Molecular Cell , vol.20 , Issue.1 , pp. 3-7
    • Sullivan, C.S.1    Ganem, D.2
  • 73
    • 24644437266 scopus 로고    scopus 로고
    • The elegance of the microRNAs: A neuronal perspective
    • K S Kosik A M Krichevsky The elegance of the microRNAs: a neuronal perspective. Neuron 47 6 2005 779 782
    • (2005) Neuron , vol.47 , Issue.6 , pp. 779-782
    • Kosik, K.S.1    Krichevsky, A.M.2
  • 74
    • 23344438420 scopus 로고    scopus 로고
    • SiRNA-mediated off-target gene silencing triggered by a 7 nt complementation
    • X Lin X Ruan M G Anderson siRNA-mediated off-target gene silencing triggered by a 7 nt complementation. Nucleic Acids Research 33 14 2005 4527 4535
    • (2005) Nucleic Acids Research , vol.33 , Issue.14 , pp. 4527-4535
    • Lin, X.1    Ruan, X.2    Anderson, M.G.3
  • 75
    • 0842346323 scopus 로고    scopus 로고
    • Long-lasting RNAi activity in mammalian neurons
    • K Omi K Tokunaga H Hohjoh Long-lasting RNAi activity in mammalian neurons. FEBS Letters 558 1-3 2004 89 95
    • (2004) FEBS Letters , vol.558 , Issue.1-3 , pp. 89-95
    • Omi, K.1    Tokunaga, K.2    Hohjoh, H.3
  • 77
    • 22844448088 scopus 로고    scopus 로고
    • Functional polarity is introduced by Dicer processing of short substrate RNAs
    • S D Rose D-H Kim M Amarzguioui Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Research 33 13 2005 4140 4156
    • (2005) Nucleic Acids Research , vol.33 , Issue.13 , pp. 4140-4156
    • Rose, S.D.1    Kim, D.-H.2    Amarzguioui, M.3
  • 78
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • H Zhang F A Kolb V Brondani E Billy W Filipowicz Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO Journal 21 21 2002 5875 5885
    • (2002) EMBO Journal , vol.21 , Issue.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 79
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • H Zhang F A Kolb L Jaskiewicz E Westhof W Filipowicz Single processing center models for human Dicer and bacterial RNase III. Cell 118 1 2004 57 68
    • (2004) Cell , vol.118 , Issue.1 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 80
    • 17844363243 scopus 로고    scopus 로고
    • The contributions of dsRNA structure to Dicer specificity and efficiency
    • A Vermeulen L Behlen A Reynolds The contributions of dsRNA structure to Dicer specificity and efficiency. RNA 11 5 2005 674 682
    • (2005) RNA , vol.11 , Issue.5 , pp. 674-682
    • Vermeulen, A.1    Behlen, L.2    Reynolds, A.3
  • 81
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • T R Brummelkamp R Bernards R Agami A system for stable expression of short interfering RNAs in mammalian cells. Science 296 5567 2002 550 553
    • (2002) Science , vol.296 , Issue.5567 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 85
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • N S Lee T Dohjima G Bauer Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nature Biotechnology 20 5 2002 500 505
    • (2002) Nature Biotechnology , vol.20 , Issue.5 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3
  • 86
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • C P Paul P D Good I Winer D R Engelke Effective expression of small interfering RNA in human cells. Nature Biotechnology 20 5 2002 505 508
    • (2002) Nature Biotechnology , vol.20 , Issue.5 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 88
    • 0037213559 scopus 로고    scopus 로고
    • Mammalian RNAi for the masses
    • Y Shi Mammalian RNAi for the masses. Trends in Genetics 19 1 2003 9 12
    • (2003) Trends in Genetics , vol.19 , Issue.1 , pp. 9-12
    • Shi, Y.1
  • 89
    • 27644436787 scopus 로고    scopus 로고
    • Second-generation shRNA libraries covering the mouse and human genomes
    • J M Silva M Z Li K Chang Second-generation shRNA libraries covering the mouse and human genomes. Nature Genetics 37 11 2005 1281 1288
    • (2005) Nature Genetics , vol.37 , Issue.11 , pp. 1281-1288
    • Silva, J.M.1    Li, M.Z.2    Chang, K.3
  • 91
    • 9144225636 scopus 로고    scopus 로고
    • The microprocessor complex mediates the genesis of microRNAs
    • R I Gregory K-P Yan G Amuthan The microprocessor complex mediates the genesis of microRNAs. Nature 432 7014 2004 235 240
    • (2004) Nature , vol.432 , Issue.7014 , pp. 235-240
    • Gregory, R.I.1    Yan, K.-P.2    Amuthan, G.3
  • 93
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Y Lee C Ahn J Han The nuclear RNase III Drosha initiates microRNA processing. Nature 425 6956 2003 415 419
    • (2003) Nature , vol.425 , Issue.6956 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 94
    • 0037425583 scopus 로고    scopus 로고
    • Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors
    • N Doi S Zenno R Ueda H Ohki-Hamazaki K Ui-Tei K Saigo Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors. Current Biology 13 1 2003 41 46
    • (2003) Current Biology , vol.13 , Issue.1 , pp. 41-46
    • Doi, N.1    Zenno, S.2    Ueda, R.3    Ohki-Hamazaki, H.4    Ui-Tei, K.5    Saigo, K.6
  • 95
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • J.-J Song S K Smith G J Hannon L Joshua-Tor Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305 5689 2004 1434 1437
    • (2004) Science , vol.305 , Issue.5689 , pp. 1434-1437
    • Song, J.-J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 96
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • J-B Ma K Ye D J Patel Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429 6989 2004 318 322
    • (2004) Nature , vol.429 , Issue.6989 , pp. 318-322
    • Ma, J.-B.1    Ye, K.2    Patel, D.J.3
  • 97
    • 15844371219 scopus 로고    scopus 로고
    • Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
    • J-B Ma Y-R Yuan G Meister Y Pei T Tuschl D J Patel Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434 7033 2005 666 670
    • (2005) Nature , vol.434 , Issue.7033 , pp. 666-670
    • Ma, J.-B.1    Yuan, Y.-R.2    Meister, G.3    Pei, Y.4    Tuschl, T.5    Patel, D.J.6
  • 98
    • 33645763485 scopus 로고    scopus 로고
    • Cleavage of the siRNA passenger strand during RISC assembly in human cells
    • P J Leuschner S L Ameres S Kueng J Martinez Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Reports 7 3 2006 314 320
    • (2006) EMBO Reports , vol.7 , Issue.3 , pp. 314-320
    • Leuschner, P.J.1    Ameres, S.L.2    Kueng, S.3    Martinez, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.