RNAi: A new technology in the post-genomic sequencing era

Journal of Neurogenetics

Volumn 15, Issue 3-4, 2001, Pages 193-204

  Ueda, Ryu ^a  

^a MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

Author keywords

Gene silencing; Reverse genetics; RNA interface

Indexed keywords

GENE PRODUCT; RNA;

ANIMAL CELL; COMPUTER PREDICTION; GENE EXPRESSION; GENE SEQUENCE; GENE TECHNOLOGY; GENETIC ANALYSIS; GENOME ANALYSIS; MOLECULAR GENETICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REVIEW; RNAI TECHNOLOGY;

ANIMALIA;

EID: 0035738661     PISSN: 01677063     EISSN: None     Source Type: Journal    
DOI: 10.3109/01677060109167376     Document Type: Review

References (50)

1. Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA
2. Double-stranded RNA as a template for gene silencing
3. Role for a bidentate ribonuclease in the initiation step of RNA interference
4. RNA interference can target pre-mRNA: Consequences for gene expression in a Caenorhabditis elegans operon
5. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
6. dsRNA-mediated gene silencing in cultured Drosophila cells: A tissue culture model for the analysis of RNA interference
7. Gene silencing by double-stranded RNA
8. Gene silencing in worms and fungi
9. Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana
10. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
11. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
12. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
13. A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans
14. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
15. RNA interference is mediated by 21- and 22-nucleotide RNAs
16. Requirement of sense transcription of homology-dependent virus resistance and trans-inactivation
17. AGOI, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
18. Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle
19. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
20. Temperature-dependent gene silencing by an expressed inverted repeat in Drosophila
21. Genetic requirements for inheritance of RNAi in C. elegans
22. par-1, a gene required for establishing polarity in C. elegans embryo, encodes a putative Ser/Thr kinase that is asymmetrically distributed
23. A species of small antisense RNA in post-transcriptional gene silencing in plants
24. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
25. Chromatin silencing and the maintenance of a functional germline in Caenorhabditis elegans
26. Heritable gene silencing in Drosophila using double-stranded RNA
27. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
28. A genetic link between co-suppression and RNA interference in C. elegans
29. Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA
30. Silencing of developmental genes in Hydra
31. Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants
32. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
33. Introduction of a chimeric chalcone synthase gene in petunia results in reversible cosuppression of homologous genes in trans
34. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
35. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
36. Cosuppression in Drosophila gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb-dependent
37. Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
38. Homology-dependent gene silencing in Paramecium
39. EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans
40. Expression of a truncated tomato polygalacturonase gene inhibits expression of the endogenous gene in transgenic plants
41. RNAi in C. elegans: Soaking in the genome sequence
42. The rde-1 gene, RNA interference and transposon silencing in C. elegans
43. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
44. Specific interference by ingested dsRNA
45. Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
46. Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover
47. Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters
48. RNA-directed de novo methylation of genomic sequences in plants
49. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
50. RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21-23 nucleotide intervals