Efficient RNA interference depends on global context of the target sequence: Quantitative analysis of silencing efficiency using Eulerian graph representation of siRNA

Nucleic Acids Research

Volumn 32, Issue 4, 2004, Pages 1469-1479

  Pancoska, Petr ^b   Moravek, Zdenek ^a   Moll, Ute M ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INTERCELLULAR ADHESION MOLECULE 1; LAMININ; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SMALL INTERFERING RNA; MESSENGER RNA;

ALGORITHM; ARTICLE; CELL LINE; CELL SPECIFICITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS HYBRIDIZATION; GENE SILENCING; HYPOTHESIS; MATHEMATICAL COMPUTING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; RNA CONFORMATION; RNA DEGRADATION; RNA HYBRIDIZATION; RNA INTERFERENCE; RNA SEQUENCE; RNA STABILITY; THERMODYNAMICS; BIOLOGY; CHEMISTRY; EVALUATION; HELA CELL; HUMAN; METHODOLOGY; SEQUENCE ANALYSIS; THEORETICAL MODEL;

BASE SEQUENCE; COMPUTATIONAL BIOLOGY; HELA CELLS; HUMANS; MODELS, THEORETICAL; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, RNA;

EID: 2542607603     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh314     Document Type: Article

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