Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR

Journal of Biological Chemistry

Volumn 274, Issue 9, 1999, Pages 5953-5962

  Abraham, Ninan ^a,b   Stojdl, David F ^a,b   Duncan, Peter I ^c   Méthot, Nathalie ^d   Ishii, Tetsu ^e   Dubé, Manon ^a   Vanderhyden, Barbara C ^a   Atkins, Harold L ^a,f   Gray, Douglas A ^a,b   McBurney, Michael W ^a,b   Koromilas, Antonis E ^e   Brown, Earl G ^b   Sonenberg, Nahum ^d   Bell, John C ^a,b  

^a OTTAWA REGIONAL CANCER CENTRE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d MCGILL UNIVERSITY   (Canada)

^e MCGILL UNIVERSITY   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DOUBLE STRANDED RNA; ERYTHROPOIETIN; GAMMA INTERFERON; INITIATION FACTOR 2; PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; BURST FORMING UNIT E; CATALYSIS; CONTROLLED STUDY; EMBRYO; FIBROBLAST; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; TRANSGENIC MOUSE; VACCINIA VIRUS;

ANIMALS; ANTIVIRAL AGENTS; APOPTOSIS; CATALYTIC DOMAIN; CYTOKINES; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; INTERFERONS; MICE; MICE, TRANSGENIC; MUTAGENESIS; ORTHOMYXOVIRIDAE; OXIDATIVE STRESS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; VACCINIA VIRUS;

ANIMALIA; EUKARYOTA; INFLUENZA VIRUS; MUS MUSCULUS; RODENTIA; VACCINIA; VACCINIA VIRUS;

EID: 0033605371     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.9.5953     Document Type: Article

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