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Volumn 20, Issue 13, 2000, Pages 4532-4542

PKR stimulates NF-κB irrespective of its kinase function by interacting with the IκB kinase complex

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2; INTERFERON; PHOSPHOTRANSFERASE; PROTEIN INHIBITOR; TRANSCRIPTION FACTOR;

EID: 0034082457     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.13.4532-4542.2000     Document Type: Article
Times cited : (191)

References (65)
  • 1
    • 0028970734 scopus 로고
    • Stimulation-dependent ΙκΒ phosphorylation marks the NF-κΒ inhibitor for degradation via the ubiquitin-proteasome pathway
    • Alkalay, I., A. Yaron, A. Hatzubai, A. Orian, A. Ciechanover, and Y. Ben-Neriah. 1995. Stimulation-dependent ΙκΒ phosphorylation marks the NF-κΒ inhibitor for degradation via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA 92:10599-10603.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10599-10603
    • Alkalay, I.1    Yaron, A.2    Hatzubai, A.3    Orian, A.4    Ciechanover, A.5    Ben-Neriah, Y.6
  • 2
    • 0030747128 scopus 로고    scopus 로고
    • NF-κΒ as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle, P., and V. Baichwal. 1997. NF-κΒ as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65:111-136.
    • (1997) Adv. Immunol. , vol.65 , pp. 111-136
    • Baeuerle, P.1    Baichwal, V.2
  • 3
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κΒ and ΙκΒ proteins: New discoveries and insights
    • Baldwin, A. 1996. The NF-κΒ and ΙκΒ proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-681
    • Baldwin, A.1
  • 4
    • 0031014063 scopus 로고    scopus 로고
    • Oncogenic potential of TAR RNA-binding TRBP and its regulatory interaction with protein kinase R
    • Benkirane, M., C. Neuveut, R. F. Chun, S. M. Smith, C. E. Samuel, A. Gatignol, and K.-T. Jeang. 1997. Oncogenic potential of TAR RNA-binding TRBP and its regulatory interaction with protein kinase R. EMBO J. 16: 611-624.
    • (1997) EMBO J. , vol.16 , pp. 611-624
    • Benkirane, M.1    Neuveut, C.2    Chun, R.F.3    Smith, S.M.4    Samuel, C.E.5    Gatignol, A.6    Jeang, K.-T.7
  • 5
    • 0001598487 scopus 로고    scopus 로고
    • Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2α kinase
    • Berlanga, J. J., J. Santoyo, and C. De Haro. 1999. Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2α kinase. Eur. J. Biochem. 265:754-762.
    • (1999) Eur. J. Biochem. , vol.265 , pp. 754-762
    • Berlanga, J.J.1    Santoyo, J.2    De Haro, C.3
  • 6
    • 0033610887 scopus 로고    scopus 로고
    • Characterization of the hemin-sensitive eukaryotic initiation factor 2α kinase from mouse nonerythroid cells
    • Berlanga, J. J., S. Herrero, and C. De Haro. 1998. Characterization of the hemin-sensitive eukaryotic initiation factor 2α kinase from mouse nonerythroid cells. J. Biol. Chem. 273:32340-32346.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32340-32346
    • Berlanga, J.J.1    Herrero, S.2    De Haro, C.3
  • 7
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets ΙκΒα to the ubiquitin-proteasome pathway
    • Chen, Z., J. Hagler, V. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. 1995. Signal-induced site-specific phosphorylation targets ΙκΒα to the ubiquitin-proteasome pathway. Genes Dev. 9:1586-1597.
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 8
    • 0026557914 scopus 로고
    • Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2
    • Chong, K., L. Feng, T. F. Donahue, J. D. Friesen, E. Meurs, A. G. Hovanessian, and B. R. G. Williams. 1992. Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2. EMBO J. 11:1553-1562.
    • (1992) EMBO J. , vol.11 , pp. 1553-1562
    • Chong, K.1    Feng, L.2    Donahue, T.F.3    Friesen, J.D.4    Meurs, E.5    Hovanessian, A.G.6    Williams, B.R.G.7
  • 10
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • Clemens, M. J., and E. Androulla. 1997. The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Res. 17:503-524.
    • (1997) J. Interferon Res. , vol.17 , pp. 503-524
    • Clemens, M.J.1    Androulla, E.2
  • 12
    • 0031037913 scopus 로고    scopus 로고
    • Characterization of a mutant cell line that does not activate NF-κΒ in response to multiple stimuli
    • Courtois, G., S. T. Whiteside, C. H. Sibley, and A. Israel. 1997. Characterization of a mutant cell line that does not activate NF-κΒ in response to multiple stimuli. Mol. Cell. Biol. 17:1441-1449.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1441-1449
    • Courtois, G.1    Whiteside, S.T.2    Sibley, C.H.3    Israel, A.4
  • 13
    • 0029785474 scopus 로고    scopus 로고
    • The kinase insert domain of interferon-induced protein kinase PKR is required for activity but not for interaction with the pseudosubstrate K3L
    • Craig, A., G. Cosentino, O. Douze, and N. Sonenberg. 1996. The kinase insert domain of interferon-induced protein kinase PKR is required for activity but not for interaction with the pseudosubstrate K3L. J. Biol. Chem. 271:24526-24533.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24526-24533
    • Craig, A.1    Cosentino, G.2    Douze, O.3    Sonenberg, N.4
  • 15
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive ΙκΒ kinase that activates the transcription factor NF-κΒ
    • DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive ΙκΒ kinase that activates the transcription factor NF-κΒ. Nature 388:548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 16
    • 0001488150 scopus 로고
    • Tumor necrosis factor a activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-κΒ sites in the long terminal repeat
    • Duh, E. J., W. J. Maury, T. M. Folks, A. S. Fauci, and A. B. Rabson. 1989. Tumor necrosis factor a activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-κΒ sites in the long terminal repeat. Proc. Natl. Acad. Sci. USA 86:5974-5978.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5974-5978
    • Duh, E.J.1    Maury, W.J.2    Folks, T.M.3    Fauci, A.S.4    Rabson, A.B.5
  • 17
    • 0032894113 scopus 로고    scopus 로고
    • Apoptosis: An innate immune response to virus infection
    • Everett, H., and G. McFadden. 1999. Apoptosis: an innate immune response to virus infection. Trends Microbiol. 7:160-165.
    • (1999) Trends Microbiol. , vol.7 , pp. 160-165
    • Everett, H.1    McFadden, G.2
  • 18
    • 0344731406 scopus 로고    scopus 로고
    • Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the α subunit of eukaryotic translation initiation factor 2 and NF-κΒ
    • Gil, J., J. Alcami, and M. Esteban. 1999. Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the α subunit of eukaryotic translation initiation factor 2 and NF-κΒ. Mol. Cell. Biol. 19: 4653-4663.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4653-4663
    • Gil, J.1    Alcami, J.2    Esteban, M.3
  • 19
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
    • Harding, H. P., Y. Zhang, and D. Ron. 1999. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397:271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 20
    • 0026523562 scopus 로고
    • Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κΒ subunit
    • Henkel, T., U. Zabel, K. Van Zee, J. Muller, E. Fanning, and P. A. Baeuerle. 1992. Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κΒ subunit. Cell 68:1121-1133.
    • (1992) Cell , vol.68 , pp. 1121-1133
    • Henkel, T.1    Zabel, U.2    Van K, Z.3    Muller, J.4    Fanning, E.5    Baeuerle, P.A.6
  • 21
    • 0025832056 scopus 로고
    • Translational control in mammalian cells
    • Hershey, J. W. 1991. Translational control in mammalian cells. Annu. Rev. Biochem. 60:717-755.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 717-755
    • Hershey, J.W.1
  • 22
    • 0024833410 scopus 로고
    • The double-stranded RNA-activated protein kinase induced by interferon: DsRNA-PK
    • Hovanessian, A. G. 1989. The double-stranded RNA-activated protein kinase induced by interferon: dsRNA-PK. J. Interferon Res. 9:641-647.
    • (1989) J. Interferon Res. , vol.9 , pp. 641-647
    • Hovanessian, A.G.1
  • 23
    • 0029949257 scopus 로고    scopus 로고
    • TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
    • Hsu, H., J. Huang, H.-B. Shu, V. Baichwal, and D. V. Goeddel. 1996. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4:387-396.
    • (1996) Immunity , vol.4 , pp. 387-396
    • Hsu, H.1    Huang, J.2    Shu, H.-B.3    Baichwal, V.4    Goeddel, D.V.5
  • 24
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKK α subunit of the ΙκΒ kinase
    • Hu, Y., V. Baud, M. Delhase, P. Zhang, T. Deerinck, M. Ellisman, R. Johnson, and M. Karin. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKK α subunit of the ΙκΒ kinase. Science 284:316-320.
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 27
    • 0026326821 scopus 로고
    • Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
    • Knighton, D. R., J. H. Zheng, L. F. Ten Eyck, N. H. Xuong, S. S. Taylor, and J. M. Sowadski. 1991. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253:414-420.
    • (1991) Science , vol.253 , pp. 414-420
    • Knighton, D.R.1    Zheng, J.H.2    Eyck, L.F.T.3    Xuong, N.H.4    Taylor, S.S.5    Sowadski, J.M.6
  • 28
    • 0028985037 scopus 로고
    • NF-κΒ: Ten years after
    • Kopp, E., and S. Gosh. 1995. NF-κΒ: ten years after. Adv. Immunol. 58:1-27.
    • (1995) Adv. Immunol. , vol.58 , pp. 1-27
    • Kopp, E.1    Gosh, S.2
  • 29
    • 0028332026 scopus 로고
    • The dsRNA-dependent protein kinase, PKR, activates transcription factor NF-κΒ by phosphorylating ΙκΒ
    • Kumar, A., J. Haque, J. Lacoste, J. Hiscott, and B. R. G. Williams. 1994. The dsRNA-dependent protein kinase, PKR, activates transcription factor NF-κΒ by phosphorylating ΙκΒ. Proc. Natl. Acad. Sci. USA 91:6288-6292.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6288-6292
    • Kumar, A.1    Haque, J.2    Lacoste, J.3    Hiscott, J.4    Williams, B.R.G.5
  • 30
    • 17444449609 scopus 로고    scopus 로고
    • Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-κΒ
    • Kumar, A., Y. L. Yang, V. Flati, S. Der, S. Kadereit, A. Deb, J. Hapque, L. Reis, C. Weissmann, and B. R. Williams. 1996. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-κΒ. EMBO J. 16:406-416.
    • (1996) EMBO J. , vol.16 , pp. 406-416
    • Kumar, A.1    Yang, Y.L.2    Flati, V.3    Der, S.4    Kadereit, S.5    Deb, A.6    Hapque, J.7    Reis, L.8    Weissmann, C.9    Williams, B.R.10
  • 31
    • 0345064267 scopus 로고
    • Monoclonal antibodies to interferon induced 68,000 Mr protein and their use for the detection of double-stranded RNA dependent protein kinase in human cells
    • Laurent, A. G., B. Krust, J. Galabru, J. Svab, and A. G. Hovanessian. 1985. Monoclonal antibodies to interferon induced 68,000 Mr protein and their use for the detection of double-stranded RNA dependent protein kinase in human cells. Proc. Natl. Acad. Sci. USA 82:4341-4345.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4341-4345
    • Laurent, A.G.1    Krust, B.2    Galabru, J.3    Svab, J.4    Hovanessian, A.G.5
  • 32
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the ΙκΒ α complex by MEKK1, a kinase of the JNK pathway
    • Lee, F., J. Hagler, Z. Chen, and T. Maniatis. 1997. Activation of the ΙκΒ α complex by MEKK1, a kinase of the JNK pathway. Cell 88:213-222.
    • (1997) Cell , vol.88 , pp. 213-222
    • Lee, F.1    Hagler, J.2    Chen, Z.3    Maniatis, T.4
  • 33
    • 0033537739 scopus 로고    scopus 로고
    • Severe liver degeneration in mice lacking the ΙκΒ kinase 2 gene
    • Li, Q., D. Van Antwerp, F. Mercurio, K. Lee, and I. Verma. 1999. Severe liver degeneration in mice lacking the ΙκΒ kinase 2 gene. Science 284:321-325.
    • (1999) Science , vol.284 , pp. 321-325
    • Li, Q.1    Van Antwerp, D.2    Mercurio, F.3    Lee, K.4    Verma, I.5
  • 34
    • 0033002994 scopus 로고    scopus 로고
    • Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase
    • Li, X., M. Commane, C. Burns, K. Vithalani, Z. Cao, and G. R. Stark. 1999. Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase. Mol. Cell. Biol. 19:4643-4652.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4643-4652
    • Li, X.1    Commane, M.2    Burns, C.3    Vithalani, K.4    Cao, Z.5    Stark, G.R.6
  • 35
    • 0031901636 scopus 로고    scopus 로고
    • RNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infection
    • Li, X. L., J. A. Blackford, and B. A. Hassel. 1998. RNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infection. J. Virol. 72:2752-2759.
    • (1998) J. Virol. , vol.72 , pp. 2752-2759
    • Li, X.L.1    Blackford, J.A.2    Hassel, B.A.3
  • 36
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κΒ induction by TNF, CD95 and IL-1
    • Malinin, N., M. Boldin, A. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κΒ induction by TNF, CD95 and IL-1. Nature 385:540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.1    Boldin, M.2    Kovalenko, A.3    Wallach, D.4
  • 39
    • 0032403447 scopus 로고    scopus 로고
    • 2′,5′-Oligoadenylate-antisense chimeras cause RNAse L to selectively degrade bcr/abl mRNA in chronic myelogenous leukemia cells
    • Maran, A., C. F. Waller, J. M. Paranjape, G. Li, W. Xiao, K. Zhang, et al. 1998. 2′,5′-Oligoadenylate-antisense chimeras cause RNAse L to selectively degrade bcr/abl mRNA in chronic myelogenous leukemia cells. Blood 92: 4336-4343.
    • (1998) Blood , vol.92 , pp. 4336-4343
    • Maran, A.1    Waller, C.F.2    Paranjape, J.M.3    Li, G.4    Xiao, W.5    Zhang, K.6
  • 40
    • 0032479145 scopus 로고    scopus 로고
    • RIP2 is a novel NF-κΒ-activating and cell death-inducing kinase
    • McCarthy, J. V., J. Ni, and V. M. Dixit. 1998. RIP2 is a novel NF-κΒ-activating and cell death-inducing kinase. J. Biol. Chem. 273:16968-16975.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16968-16975
    • McCarthy, J.V.1    Ni, J.2    Dixit, V.M.3
  • 42
    • 0025298202 scopus 로고
    • Molecular cloning and characterization of cDNA encoding human double-stranded RNA activated protein kinase induced by interferon
    • Meurs, E., K. Chong, J. Galabru, S. B. Thomas, I. M. Kerr, B. R. G. Williams, and A. G. Hovanessian. 1990. Molecular cloning and characterization of cDNA encoding human double-stranded RNA activated protein kinase induced by interferon. Cell 62:379-390.
    • (1990) Cell , vol.62 , pp. 379-390
    • Meurs, E.1    Chong, K.2    Galabru, J.3    Thomas, S.B.4    Kerr, I.M.5    Williams, B.R.G.6    Hovanessian, A.G.7
  • 43
    • 0029609175 scopus 로고
    • Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-1 LTR
    • Meurs, E. F., N. McMillan, B. R. Williams, A. G. Hovanessian, and P. J. Southern. 1995. Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-1 LTR. Virology 214:653-659.
    • (1995) Virology , vol.214 , pp. 653-659
    • Meurs, E.F.1    McMillan, N.2    Williams, B.R.3    Hovanessian, A.G.4    Southern, P.J.5
  • 44
    • 0026929934 scopus 로고
    • Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eucaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth
    • Meurs, E. F., Y. Watanabe, S. Kadereit, G. N. Barber, M. G. Katze, K. Chong, B. R. G. Williams, and A. G. Hovanessian. 1992. Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eucaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66:5805-5814.
    • (1992) J. Virol. , vol.66 , pp. 5805-5814
    • Meurs, E.F.1    Watanabe, Y.2    Kadereit, S.3    Barber, G.N.4    Katze, M.G.5    Chong, K.6    Williams, B.R.G.7    Hovanessian, A.G.8
  • 45
    • 0028077284 scopus 로고
    • Tax induces nuclear translocation of NF-κΒ through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of ΙκΒα/MAD3
    • Munoz, E., G. Courtois, P. Veschambre, P. Jalinot, and A. Israel. 1994. Tax induces nuclear translocation of NF-κΒ through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of ΙκΒα/MAD3. J. Virol. 68:8035-8044.
    • (1994) J. Virol. , vol.68 , pp. 8035-8044
    • Munoz, E.1    Courtois, G.2    Veschambre, P.3    Jalinot, P.4    Israel, A.5
  • 47
    • 0029841348 scopus 로고    scopus 로고
    • Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties
    • Patel, R. C., P. Stanton, and G. C. Sen. 1996. Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties. J. Biol. Chem. 271:25657-25663.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25657-25663
    • Patel, R.C.1    Stanton, P.2    Sen, G.C.3
  • 48
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterization of an IkappaB kinase
    • Regnier, C. H., H. Y. Song, X. Gao, D. V. Goeddel, Z. Cao, and M. Rothe. 1997. Identification and characterization of an IkappaB kinase. Cell 90:373-383.
    • (1997) Cell , vol.90 , pp. 373-383
    • Regnier, C.H.1    Song, H.Y.2    Gao, X.3    Goeddel, D.V.4    Cao, Z.5    Rothe, M.6
  • 49
    • 0032541657 scopus 로고    scopus 로고
    • IKK-γ is an essential regulatory subunit of the ΙκΒ kinase complex
    • Rothwarf, D., E. Zandi, G. Natoli, and M. Karin. 1998. IKK-γ is an essential regulatory subunit of the ΙκΒ kinase complex. Nature 395:297-300.
    • (1998) Nature , vol.395 , pp. 297-300
    • Rothwarf, D.1    Zandi, E.2    Natoli, G.3    Karin, M.4
  • 50
    • 0025739093 scopus 로고
    • Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • Samuel, C. E. 1991. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183:1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 51
    • 0030911360 scopus 로고    scopus 로고
    • Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2α (eIF-2α) kinase from Drosaphila melanogaster
    • Santoyo, J., J. Alcalde, R. Mendez, D. Pulido, and C. De Haro. 1997. Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2α (eIF-2α) kinase from Drosaphila melanogaster. J. Biol. Chem. 272: 12544-12550.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12544-12550
    • Santoyo, J.1    Alcalde, J.2    Mendez, R.3    Pulido, D.4    De Haro, C.5
  • 52
    • 0032560477 scopus 로고    scopus 로고
    • Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment
    • Seeler, J. S., A. Marchio, D. Sitterlin, C. Transy, and A. Dejean. 1998. Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment. Proc. Natl. Acad. Sci. USA 95:7316-7321.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7316-7321
    • Seeler, J.S.1    Marchio, A.2    Sitterlin, D.3    Transy, C.4    Dejean, A.5
  • 53
    • 0031755020 scopus 로고    scopus 로고
    • Identification and characterization of pancreatic eukaryotic initiation factor 2 α-subunit, PEK, involved in translational control
    • Shi, Y., K. M. Vattem, R. Sood, J. An, J. Liang, L. Stramm, and R. C. Wek. 1998. Identification and characterization of pancreatic eukaryotic initiation factor 2 α-subunit, PEK, involved in translational control. Mol. Cell. Biol. 18:7499-7509.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7499-7509
    • Shi, Y.1    Vattem, K.M.2    Sood, R.3    An, J.4    Liang, J.5    Stramm, L.6    Wek, R.C.7
  • 54
    • 0030613758 scopus 로고    scopus 로고
    • NF-κΒ activation: The ΙκΒ kinase revealed?
    • Stancovski, I., and D. Baltimore. 1997. NF-κΒ activation: the ΙκΒ kinase revealed? Cell 91:299-302.
    • (1997) Cell , vol.91 , pp. 299-302
    • Stancovski, I.1    Baltimore, D.2
  • 56
    • 0029858348 scopus 로고    scopus 로고
    • RIP mediates tumor necrosis factor receptor 1 activation of NF-κΒ but not Fas/APO-1-initiated apoptosis
    • Ting, A. T., F. X. Pimentel-Muinos, and B. Seed. 1996. RIP mediates tumor necrosis factor receptor 1 activation of NF-κΒ but not Fas/APO-1-initiated apoptosis. EMBO J. 15:6189-6196.
    • (1996) EMBO J. , vol.15 , pp. 6189-6196
    • Ting, A.T.1    Pimentel-Muinos, F.X.2    Seed, B.3
  • 57
    • 0027524248 scopus 로고
    • HTLV-1 encoded Tax in association with NF-κΒ precursor p105 enhances nuclear localization of NF-κΒ p50 and p65 in transfected cells
    • Watanabe, M., M. Muramatsu, H. Hirai, T. Suzuki, J. Fujisawa, M. Yoshida, K. Arai, and N. Arai. 1993. HTLV-1 encoded Tax in association with NF-κΒ precursor p105 enhances nuclear localization of NF-κΒ p50 and p65 in transfected cells. Oncogene 8:2949-2958.
    • (1993) Oncogene , vol.8 , pp. 2949-2958
    • Watanabe, M.1    Muramatsu, M.2    Hirai, H.3    Suzuki, T.4    Fujisawa, J.5    Yoshida, M.6    Arai, K.7    Arai, N.8
  • 58
    • 0028797781 scopus 로고
    • The role of the dsRNA-activated protein kinase, PKR, in signal transduction
    • Williams, B. R. G. 1995. The role of the dsRNA-activated protein kinase, PKR, in signal transduction. Semin. Virol. 6:191-202.
    • (1995) Semin. Virol. , vol.6 , pp. 191-202
    • Williams, B.R.G.1
  • 59
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the ΙκΒ kinase complex essential for NF-κΒ activation
    • Yamaoka, S., G. Courtois, C. Bessia, S. T. Whiteside, R. Weil, F. Agout, H. E. Kirk, R. J. Kay, and A. Israel. 1998. Complementation cloning of NEMO, a component of the ΙκΒ kinase complex essential for NF-κΒ activation. Cell 93:1231-1240.
    • (1998) Cell , vol.93 , pp. 1231-1240
    • Yamaoka, S.1    Courtois, G.2    Bessia, C.3    Whiteside, S.T.4    Weil, R.5    Agout, F.6    Kirk, H.E.7    Kay, R.J.8    Israel, A.9
  • 63
    • 0030613551 scopus 로고    scopus 로고
    • The ΙκΒ kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for ΙκΒ phosphorylation and NF-κΒ activation
    • Zandi, E., D. M. Rothwarf, M. Delhasse, M. Hayakawa, and M. Karin. 1997. The ΙκΒ kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for ΙκΒ phosphorylation and NF-κΒ activation. Cell 91: 243-252.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhasse, M.3    Hayakawa, M.4    Karin, M.5
  • 64
    • 0027510449 scopus 로고
    • Expression cloning of 2-5A-dependent RNAse: A uniquely regulatory mediator of interferon action
    • Zhou, A., B. A. Hassel, and R. H. Silverman. 1993. Expression cloning of 2-5A-dependent RNAse: a uniquely regulatory mediator of interferon action. Cell 72:753-765.
    • (1993) Cell , vol.72 , pp. 753-765
    • Zhou, A.1    Hassel, B.A.2    Silverman, R.H.3
  • 65
    • 0024281414 scopus 로고
    • 2-Aminopurine selectively inhibits the induction of β-interferon, c-fos, and c-myc gene expression
    • Zinn, K., A. Keller, L. A. Whittemore, and T. Maniatis. 1988. 2-Aminopurine selectively inhibits the induction of β-interferon, c-fos, and c-myc gene expression. Science 240:210-213.
    • (1988) Science , vol.240 , pp. 210-213
    • Zinn, K.1    Keller, A.2    Whittemore, L.A.3    Maniatis, T.4


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