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Volumn 24, Issue 8, 2004, Pages 3415-3429

Control of α Subunit of Eukaryotic Translation Initiation Factor 2 (eIF2α) Phosphorylation by the Human Papillomavirus Type 18 E6 Oncoprotein: Implications for eIF2α-Dependent Gene Expression and Cell Death

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; INTERFERON; PROTEIN E6; PROTEIN KINASE; PROTEIN KINASE R; SERINE; UNCLASSIFIED DRUG;

EID: 1842505312     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.8.3415-3429.2004     Document Type: Article
Times cited : (94)

References (87)
  • 1
    • 0036270508 scopus 로고    scopus 로고
    • Egr1 transcription factor: Multiple roles in prostate tumor cell growth and survival
    • Adamson, E. D., and D. Mercola. 2002. Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival. Tumour Biol. 23:93-102.
    • (2002) Tumour Biol. , vol.23 , pp. 93-102
    • Adamson, E.D.1    Mercola, D.2
  • 2
    • 0032404120 scopus 로고    scopus 로고
    • Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
    • Balachandran, S., C. N. Kim, W. C. Yeh, T. W. Mak, K. Bhalla, and G. N. Barber. 1998. Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling. EMBO J. 17:6888-6902.
    • (1998) EMBO J. , vol.17 , pp. 6888-6902
    • Balachandran, S.1    Kim, C.N.2    Yeh, W.C.3    Mak, T.W.4    Bhalla, K.5    Barber, G.N.6
  • 3
    • 0036852215 scopus 로고    scopus 로고
    • To kill or be killed: Viral evasion of apoptosis
    • Benedict, C. A., P. S. Norris, and C. F. Ware. 2002. To kill or be killed: viral evasion of apoptosis. Nat. Immunol. 3:1013-1018.
    • (2002) Nat. Immunol. , vol.3 , pp. 1013-1018
    • Benedict, C.A.1    Norris, P.S.2    Ware, C.F.3
  • 4
    • 0029990084 scopus 로고    scopus 로고
    • Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q-associated leukemias
    • Beretta, L., M. Gahhay, R. Berger, S. M. Hanash, and N. Sonenberg. 1996. Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q-associated leukemias. Oncogene 12:1593-1596.
    • (1996) Oncogene , vol.12 , pp. 1593-1596
    • Beretta, L.1    Gahhay, M.2    Berger, R.3    Hanash, S.M.4    Sonenberg, N.5
  • 5
    • 0034668204 scopus 로고    scopus 로고
    • A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis
    • Beyaert, R., K. Heyninck, and S. Van Huffel. 2000, A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis. Biochem. Pharmacol. 60:1143-1151.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1143-1151
    • Beyaert, R.1    Heyninck, K.2    Van Huffel, S.3
  • 6
    • 0037317592 scopus 로고    scopus 로고
    • Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2
    • Brush, M. H., D. C. Weiser, and S. Shenolikar. 2003. Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol. Cell. Biol. 23:1292-1303.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1292-1303
    • Brush, M.H.1    Weiser, D.C.2    Shenolikar, S.3
  • 7
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live Forkheads
    • Burgering, B. M., and G. J. Kops. 2002. Cell cycle and death control: long live Forkheads. Trends Biochem. Sci. 27:352-360.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 352-360
    • Burgering, B.M.1    Kops, G.J.2
  • 9
    • 0001657903 scopus 로고    scopus 로고
    • Heme-regulated eIF2α kinase
    • N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Cben, J. J. 2000. Heme-regulated eIF2α kinase, p. 529-546. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (2000) Translational Control of Gene Expression , pp. 529-546
    • Cben, J.J.1
  • 10
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 11
    • 0037112524 scopus 로고    scopus 로고
    • Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line
    • Christopher, S. A., P. Diegeiman, C. W. Porter, and W. D. Kruger. 2002. Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line. Cancer Res. 62:6639-6644.
    • (2002) Cancer Res. , vol.62 , pp. 6639-6644
    • Christopher, S.A.1    Diegeiman, P.2    Porter, C.W.3    Kruger, W.D.4
  • 12
    • 0035231288 scopus 로고    scopus 로고
    • Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis
    • Clemens, M. J. 2001. Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis. Prog. Mol. Subcell. But. 27:57-89.
    • (2001) Prog. Mol. Subcell. But. , vol.27 , pp. 57-89
    • Clemens, M.J.1
  • 13
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • Clemens, M. J., and A. Elia. 1997. The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Cytokine Res. 17:503-524.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 503-524
    • Clemens, M.J.1    Elia, A.2
  • 14
    • 0027992574 scopus 로고
    • Positional reproducibility of protein spots in two-dimensional polyacrylamide gel electrophoresis using immobilised pH gradient isoelectric focusing in the first dimension: An interlaboratory comparison
    • Corbett, J. M., M. J. Dunn, A. Posch, and A. Gorg. 1994. Positional reproducibility of protein spots in two-dimensional polyacrylamide gel electrophoresis using immobilised pH gradient isoelectric focusing in the first dimension: an interlaboratory comparison. Electrophoresis 15:1205-1211.
    • (1994) Electrophoresis , vol.15 , pp. 1205-1211
    • Corbett, J.M.1    Dunn, M.J.2    Posch, A.3    Gorg, A.4
  • 15
    • 0035193540 scopus 로고    scopus 로고
    • Human papillomaviruses and their role in cervical cancer
    • Dell, G., and K. Gaston. 2001. Human papillomaviruses and their role in cervical cancer. Cell Mol. Life Sci. 58:1923-1942.
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 1923-1942
    • Dell, G.1    Gaston, K.2
  • 16
    • 0037154965 scopus 로고    scopus 로고
    • Gene-specific regulation by general translation factors
    • Dever, T. E. 2002. Gene-specific regulation by general translation factors. Cell 108:545-556.
    • (2002) Cell , vol.108 , pp. 545-556
    • Dever, T.E.1
  • 17
    • 0033541366 scopus 로고    scopus 로고
    • Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression
    • Donze, O., J. Dostie, and N. Sonenberg. 1999. Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression. Virology 256:322-329.
    • (1999) Virology , vol.256 , pp. 322-329
    • Donze, O.1    Dostie, J.2    Sonenberg, N.3
  • 18
    • 0031978858 scopus 로고    scopus 로고
    • Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma
    • Dreyling, M. H., D. Roulston, S. K. Bohlander, J. Vardiman, and O. I. Olopade. 1998. Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma. Genes Chromosomes Cancer 22:72-78.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 72-78
    • Dreyling, M.H.1    Roulston, D.2    Bohlander, S.K.3    Vardiman, J.4    Olopade, O.I.5
  • 19
    • 0029790881 scopus 로고    scopus 로고
    • Two-dimensional polyacrylamide gel electrophoresis
    • Dunn, M. J., and J. M. Corbett. 1996. Two-dimensional polyacrylamide gel electrophoresis. Methods Enzymol. 271:177-203.
    • (1996) Methods Enzymol. , vol.271 , pp. 177-203
    • Dunn, M.J.1    Corbett, J.M.2
  • 20
    • 0038521287 scopus 로고    scopus 로고
    • ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses
    • Espert, L., G. Degols, C. Gongora, D. Blondel, B. R. Williams, R. H. Silverman, and N. Mechti. 2003. ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses. J. Biol. Chem. 278:16151-16158.
    • (2003) J. Biol. Chem. , vol.278 , pp. 16151-16158
    • Espert, L.1    Degols, G.2    Gongora, C.3    Blondel, D.4    Williams, B.R.5    Silverman, R.H.6    Mechti, N.7
  • 21
    • 0343431521 scopus 로고    scopus 로고
    • Translational control of viral gene expression in eukaryotes
    • Gale, M., Jr., S. L. Tan, and M. G. Katze. 2000. Translational control of viral gene expression in eukaryotes. Microbiol. Mol. Biol. Rev. 64:239-280.
    • (2000) Microbiol. Mol. Biol. Rev. , vol.64 , pp. 239-280
    • Gale Jr., M.1    Tan, S.L.2    Katze, M.G.3
  • 22
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Gbosh, S., M. J. May, and E. B. Kopp. 1998. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Gbosh, S.1    May, M.J.2    Kopp, E.B.3
  • 23
    • 0028089004 scopus 로고
    • DNA damage induced p53 mediated transcription is inhibited by human papillomavirus type 18 E6
    • Gu, Z., D. Pim, S. Labrecque, L. Banks, and G. Matlashewski. 1994. DNA damage induced p53 mediated transcription is inhibited by human papillomavirus type 18 E6. Oncogene 9:629-633.
    • (1994) Oncogene , vol.9 , pp. 629-633
    • Gu, Z.1    Pim, D.2    Labrecque, S.3    Banks, L.4    Matlashewski, G.5
  • 24
    • 0036349075 scopus 로고    scopus 로고
    • Comparative analysis of the intracellular location of the high- and low-risk human papillomavirus oncoproteins
    • Guccione, E., P. Massimi, A. Bernat, and L. Banks. 2002. Comparative analysis of the intracellular location of the high- and low-risk human papillomavirus oncoproteins. Virology 293:20-25.
    • (2002) Virology , vol.293 , pp. 20-25
    • Guccione, E.1    Massimi, P.2    Bernat, A.3    Banks, L.4
  • 25
    • 0036437307 scopus 로고    scopus 로고
    • Transcriptional and translational control in the Mammalian unfolded protein response
    • Harding, H. P., M. Calfon, F. Urano, I. Novoa, and D. Ron. 2002. Transcriptional and translational control in the Mammalian unfolded protein response. Annu. Rev. Cell Dev. Biol. 18:575-599.
    • (2002) Annu. Rev. Cell Dev. Biol. , vol.18 , pp. 575-599
    • Harding, H.P.1    Calfon, M.2    Urano, F.3    Novoa, I.4    Ron, D.5
  • 26
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding, H. P., I. Novoa, Y. Zhang, H. Zeng, R. Wek, M. Schapira, and D. Ron. 2000. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6:1099-1108.
    • (2000) Mol. Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 27
    • 0029656197 scopus 로고    scopus 로고
    • 134.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells
    • 134.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells. J. Virol. 70:84-90.
    • (1996) J. Virol. , vol.70 , pp. 84-90
    • He, B.1    Chou, J.2    Liebermann, D.A.3    Hoffman, B.4    Roizman, B.5
  • 28
    • 0025832056 scopus 로고
    • Translational control in mammalian cells
    • Hershey, J. W. 1991. Translational control in mammalian cells. Annu. Rev. Biochem. 60:717-755.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 717-755
    • Hershey, J.W.1
  • 29
    • 0036629836 scopus 로고    scopus 로고
    • The diversity and evolution of thioredoxin reductase: New perspectives
    • Hirt, R. P., S. Muller, T. M. Emhley, and G. H. Coombs. 2002, The diversity and evolution of thioredoxin reductase: new perspectives. Trends Parasitol. 18:302-308.
    • (2002) Trends Parasitol. , vol.18 , pp. 302-308
    • Hirt, R.P.1    Muller, S.2    Emhley, T.M.3    Coombs, G.H.4
  • 31
    • 0031588601 scopus 로고    scopus 로고
    • Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line
    • Ishikawa, S., M. Kai, M. Tamari, Y. Takei, K. Takeuchi, H. Bandou, Y. Yamane, M. Ogawa, and Y. Nakamura. 1997. Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line. DNA Res. 4:35-43.
    • (1997) DNA Res. , vol.4 , pp. 35-43
    • Ishikawa, S.1    Kai, M.2    Tamari, M.3    Takei, Y.4    Takeuchi, K.5    Bandou, H.6    Yamane, Y.7    Ogawa, M.8    Nakamura, Y.9
  • 33
    • 0035969113 scopus 로고    scopus 로고
    • Function of RARα during the maturation of neutrophils
    • Kastner, P., and S. Chan. 2001. Function of RARα during the maturation of neutrophils. Oncogene 20:7178-7185.
    • (2001) Oncogene , vol.20 , pp. 7178-7185
    • Kastner, P.1    Chan, S.2
  • 34
    • 0028815704 scopus 로고
    • Regulation of the interferon-induced PKR: Can viruses cope?
    • Katze, M. G. 1995. Regulation of the interferon-induced PKR: can viruses cope? Trends Microbiol. 3:75-78.
    • (1995) Trends Microbiol. , vol.3 , pp. 75-78
    • Katze, M.G.1
  • 35
    • 0036715591 scopus 로고    scopus 로고
    • Viruses and interferon: A fight for supremacy
    • Katze, M. G., Y. He, and M. Gale, Jr. 2002. Viruses and interferon: a fight for supremacy. Nat. Rev. Immonul. 2:675-687.
    • (2002) Nat. Rev. Immonul. , vol.2 , pp. 675-687
    • Katze, M.G.1    He, Y.2    Gale Jr., M.3
  • 36
    • 0001815885 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase PKR
    • N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Kaufman, R. J. 2000. Double-stranded RNA-activated protein kinase PKR, p. 503-527. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (2000) Translational Control of Gene Expression , pp. 503-527
    • Kaufman, R.J.1
  • 37
    • 0036039798 scopus 로고    scopus 로고
    • Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities
    • Kehmeier, E., H. Ruhl, B. Voland, M. C. Stoppler, E. Androphy, and H. Stoppler. 2002. Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities. Virology 299:72-87.
    • (2002) Virology , vol.299 , pp. 72-87
    • Kehmeier, E.1    Ruhl, H.2    Voland, B.3    Stoppler, M.C.4    Androphy, E.5    Stoppler, H.6
  • 38
    • 0035225871 scopus 로고    scopus 로고
    • Regulation of translation initiation by amino acids in eukaryotic cells
    • Kimball, S. R. 2001. Regulation of translation initiation by amino acids in eukaryotic cells. Prog. Mol. Subcell. Biol. 26:155-184.
    • (2001) Prog. Mol. Subcell. Biol. , vol.26 , pp. 155-184
    • Kimball, S.R.1
  • 39
    • 0029148470 scopus 로고
    • IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR
    • Kirchboff, S., A. E. Koromilas, F. Schaper, M. Grashoff, N. Sonenberg, and H. Hauser. 1995. IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR. Oncogene 11:439-445.
    • (1995) Oncogene , vol.11 , pp. 439-445
    • Kirchboff, S.1    Koromilas, A.E.2    Schaper, F.3    Grashoff, M.4    Sonenberg, N.5    Hauser, H.6
  • 40
    • 0037275640 scopus 로고    scopus 로고
    • Keratins: A structural scaffold with emerging functions
    • Kirfel, J., T. M. Magin, and J. Reichelt. 2003. Keratins: a structural scaffold with emerging functions. Cell. Mol. Life Sci. 60:56-71.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 56-71
    • Kirfel, J.1    Magin, T.M.2    Reichelt, J.3
  • 41
    • 0034954453 scopus 로고    scopus 로고
    • Control of interferon signaling in human papillomavirus infection
    • Koromilas, A. E., S. Li, and G. Matlashewski. 2001. Control of interferon signaling in human papillomavirus infection. Cytokine Growth Factor Rev. 12:157-170.
    • (2001) Cytokine Growth Factor Rev. , vol.12 , pp. 157-170
    • Koromilas, A.E.1    Li, S.2    Matlashewski, G.3
  • 42
    • 17444449609 scopus 로고    scopus 로고
    • Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-κB
    • Kumar, A., Y. L. Yang, V. Flati, S. Der, S. Kadereit, A. Deb, J. Haque, L. Reis, C. Weissmann, and B. R. Williams. 1997. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-κB. EMBO J. 16:406-416.
    • (1997) EMBO J. , vol.16 , pp. 406-416
    • Kumar, A.1    Yang, Y.L.2    Flati, V.3    Der, S.4    Kadereit, S.5    Deb, A.6    Haque, J.7    Reis, L.8    Weissmann, C.9    Williams, B.R.10
  • 43
    • 0035988036 scopus 로고    scopus 로고
    • Counteraction of interferon-induced antiviral responses by herpes simplex viruses
    • Leib, D. A. 2002. Counteraction of interferon-induced antiviral responses by herpes simplex viruses. Curr. Top. Microbiol. Immumol. 269:171-185.
    • (2002) Curr. Top. Microbiol. Immumol. , vol.269 , pp. 171-185
    • Leib, D.A.1
  • 44
    • 3042795871 scopus 로고    scopus 로고
    • Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker
    • Leone, P. E., M. Mendiola, J. Alonso, C. Mino, and A. Pestana. 2003. Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker. BMC Cancer 3:6.
    • (2003) BMC Cancer , vol.3 , pp. 6
    • Leone, P.E.1    Mendiola, M.2    Alonso, J.3    Mino, C.4    Pestana, A.5
  • 45
    • 0035957939 scopus 로고    scopus 로고
    • Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR
    • Li, S., and A. E. Koromilas. 2001. Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR. J. Biol. Chem. 276:13881-13890.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13881-13890
    • Li, S.1    Koromilas, A.E.2
  • 46
    • 0033554631 scopus 로고    scopus 로고
    • The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha
    • Li, S., S. Labrecque, M. C. Gauzzi, A. R. Cuddihy, A. H. Wong, S. Pellegrini, G. J. Matlashewski, and A. E. Koromilas. 1999. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha. Oncogene 18:5727-5737.
    • (1999) Oncogene , vol.18 , pp. 5727-5737
    • Li, S.1    Labrecque, S.2    Gauzzi, M.C.3    Cuddihy, A.R.4    Wong, A.H.5    Pellegrini, S.6    Matlashewski, G.J.7    Koromilas, A.E.8
  • 47
    • 0034118928 scopus 로고    scopus 로고
    • A diminished activation capacity of the interferon-inducible protein kinase PKR in human T lymphocytes
    • Li, S., K. Nagai, and A. E. Koromilas. 2000. A diminished activation capacity of the interferon-inducible protein kinase PKR in human T lymphocytes. Eur. J. Biochem. 267:1598-1606.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1598-1606
    • Li, S.1    Nagai, K.2    Koromilas, A.E.3
  • 48
    • 0035956215 scopus 로고    scopus 로고
    • The human papillomavirus E6 protein and its contribution to malignant progression
    • Mantovani, F., and L. Banks. 2001. The human papillomavirus E6 protein and its contribution to malignant progression. Oncogene 20:7874-7887.
    • (2001) Oncogene , vol.20 , pp. 7874-7887
    • Mantovani, F.1    Banks, L.2
  • 49
    • 0036511615 scopus 로고    scopus 로고
    • The role of human papillomaviruses in human cancers
    • Munger, K. 2002. The role of human papillomaviruses in human cancers. Front. Biosci. 7:d641-d649.
    • (2002) Front. Biosci. , vol.7
    • Munger, K.1
  • 50
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • Munger, K., and P. M. Howley. 2002. Human papillomavirus immortalization and transformation functions. Virus Res. 89:213-228.
    • (2002) Virus Res. , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 51
    • 0036733906 scopus 로고    scopus 로고
    • The role of Epstein-Barr virus-encoded small RNAs (EBERs) in oncogenesis
    • Nanbo, A., and K. Takada. 2002. The role of Epstein-Barr virus-encoded small RNAs (EBERs) in oncogenesis. Rev. Med. Virol. 12:321-326.
    • (2002) Rev. Med. Virol. , vol.12 , pp. 321-326
    • Nanbo, A.1    Takada, K.2
  • 52
    • 0036490096 scopus 로고    scopus 로고
    • Regulators of G-protein signalling as new central nervous system drug targets
    • Neubig, R. R., and D. P. Siderovski. 2002. Regulators of G-protein signalling as new central nervous system drug targets. Nat. Rev. Drug Discov. 1:187-197.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 187-197
    • Neubig, R.R.1    Siderovski, D.P.2
  • 53
    • 0035699287 scopus 로고    scopus 로고
    • Characterization of variability in large-scale gene expression data: Implications for study design
    • Novak, J. P., R. Sladek, and T. J. Hudson. 2002. Characterization of variability in large-scale gene expression data: implications for study design. Genomics 79:104-113.
    • (2002) Genomics , vol.79 , pp. 104-113
    • Novak, J.P.1    Sladek, R.2    Hudson, T.J.3
  • 54
    • 0035947778 scopus 로고    scopus 로고
    • Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
    • Novoa, I., H. Zeng, H. P. Harding, and D. Ron. 2001. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α. J. Cell Biol. 153:1011-1022.
    • (2001) J. Cell Biol. , vol.153 , pp. 1011-1022
    • Novoa, I.1    Zeng, H.2    Harding, H.P.3    Ron, D.4
  • 55
    • 0037416211 scopus 로고    scopus 로고
    • Stress-induced gene expression requires programmed recovery from translational repression
    • Novoa, I., Y. Zhang, H. Zeng, R. Jungreis, H. P. Harding, and D. Ron. 2003. Stress-induced gene expression requires programmed recovery from translational repression. EMBO J. 22:1180-1187.
    • (2003) EMBO J. , vol.22 , pp. 1180-1187
    • Novoa, I.1    Zhang, Y.2    Zeng, H.3    Jungreis, R.4    Harding, H.P.5    Ron, D.6
  • 56
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • Olofsson, B. 1999. Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cell. Signal. 11:545-554.
    • (1999) Cell. Signal. , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 57
    • 0037089491 scopus 로고    scopus 로고
    • Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR)
    • Pataer, A., S. A. Vorburger, G. N. Barber, S. Chada, A. M. Mhashilkar, H. Zou-Yang, A. L. Stewart, S. Balachandran, J. A. Roth, K. K. Hunt, and S. G. Swisher. 2002. Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Res. 62:2239-2243.
    • (2002) Cancer Res. , vol.62 , pp. 2239-2243
    • Pataer, A.1    Vorburger, S.A.2    Barber, G.N.3    Chada, S.4    Mhashilkar, A.M.5    Zou-Yang, H.6    Stewart, A.L.7    Balachandran, S.8    Roth, J.A.9    Hunt, K.K.10    Swisher, S.G.11
  • 60
    • 0037439823 scopus 로고    scopus 로고
    • An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies
    • Protopopov, A., V. Kashuha, V. I. Zaharovska, O. V. Muravenko, M. I. Lerman, G. Klein, and E. R. Zaharovsky. 2003. An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies. Cancer Res. 63:404-412.
    • (2003) Cancer Res. , vol.63 , pp. 404-412
    • Protopopov, A.1    Kashuha, V.2    Zaharovska, V.I.3    Muravenko, O.V.4    Lerman, M.I.5    Klein, G.6    Zaharovsky, E.R.7
  • 61
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath, H., and A. Strasser. 2002. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ. 9:505-512.
    • (2002) Cell Death Differ. , vol.9 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 64
    • 0036856008 scopus 로고    scopus 로고
    • Translational control in the endoplasmic reticulum stress response
    • Ron, D. 2002. Translational control in the endoplasmic reticulum stress response. J. Clin. Investig. 110:1383-1388.
    • (2002) J. Clin. Investig. , vol.110 , pp. 1383-1388
    • Ron, D.1
  • 70
    • 0037108150 scopus 로고    scopus 로고
    • Recruitment of RNA polymerase III to its target promoters
    • Schramm, L., and N. Hernandez. 2002. Recruitment of RNA polymerase III to its target promoters. Genes Dev. 16:2593-2620.
    • (2002) Genes Dev. , vol.16 , pp. 2593-2620
    • Schramm, L.1    Hernandez, N.2
  • 71
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian, E., and M. Karin. 2002. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4:E131-E136.
    • (2002) Nat. Cell Biol. , vol.4
    • Shaulian, E.1    Karin, M.2
  • 74
    • 0029996794 scopus 로고    scopus 로고
    • Simian virus 40 large-T bypasses the translational block imposed by the phosphorylation of eIF-2 alpha
    • Swaminathan, S., P. Rajan, O. Savinova, R. Jagus, and B. Thimmapaya. 1996. Simian virus 40 large-T bypasses the translational block imposed by the phosphorylation of eIF-2 alpha. Virology 219:321-323.
    • (1996) Virology , vol.219 , pp. 321-323
    • Swaminathan, S.1    Rajan, P.2    Savinova, O.3    Jagus, R.4    Thimmapaya, B.5
  • 75
    • 0032811002 scopus 로고    scopus 로고
    • The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: A new face of death?
    • Tan, S. L., and M. G. Katze. 1999. The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death? J. Interferon Cytokine Res. 19:543-554.
    • (1999) J. Interferon Cytokine Res. , vol.19 , pp. 543-554
    • Tan, S.L.1    Katze, M.G.2
  • 76
    • 0037184034 scopus 로고    scopus 로고
    • The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation
    • Tan, S. L., S. U. Tareen, M. W. Melville, C. M. Blakely, and M. G. Katze. 2002. The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation. J. Biol. Chem. 277:36109-36117.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36109-36117
    • Tan, S.L.1    Tareen, S.U.2    Melville, M.W.3    Blakely, C.M.4    Katze, M.G.5
  • 77
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi, T., K. Ogasawara, A. Takaoka, and N. Tanaka. 2001. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19:623-655.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 78
    • 0035898611 scopus 로고    scopus 로고
    • Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR
    • Ung, T. L., C. Cao, J. Lu, K. Ozato, and T. E. Dever. 2001. Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR. EMBO J. 20:.3728-3737.
    • (2001) EMBO J. , vol.20 , pp. 3728-3737
    • Ung, T.L.1    Cao, C.2    Lu, J.3    Ozato, K.4    Dever, T.E.5
  • 80
    • 0035282062 scopus 로고    scopus 로고
    • Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization
    • Warden, S. M., C. Richardson, J. O'Donnell, Jr., D. Stapleton, B. E. Kemp, and L. A. Witters. 2001. Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. Biochem. J. 354:275-283.
    • (2001) Biochem. J. , vol.354 , pp. 275-283
    • Warden, S.M.1    Richardson, C.2    O'Donnell Jr., J.3    Stapleton, D.4    Kemp, B.E.5    Witters, L.A.6
  • 81
    • 0035958080 scopus 로고    scopus 로고
    • Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR
    • Wong, A. H., J. E. Durhin, S. Li, T. E. Dever, T. Decker, and A. E. Koromilas. 2001. Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR. J. Biol. Chem. 276:13727-13737.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13727-13737
    • Wong, A.H.1    Durhin, J.E.2    Li, S.3    Dever, T.E.4    Decker, T.5    Koromilas, A.E.6
  • 83
    • 0001665802 scopus 로고    scopus 로고
    • CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint
    • Yao, X., A. Ahrieu, Y. Zheng, K. F. Sullivan, and D. W. Cleveland. 2000. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat. Cell Biol. 2:484-491.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 484-491
    • Yao, X.1    Ahrieu, A.2    Zheng, Y.3    Sullivan, K.F.4    Cleveland, D.W.5
  • 84
    • 0036254704 scopus 로고    scopus 로고
    • Redox regulation of stress signals: Possible roles of dendritic stellate TRX producer cells (DST cell types)
    • Yodoi, J., H. Nakamura, and H. Masutani. 2002. Redox regulation of stress signals: possible roles of dendritic stellate TRX producer cells (DST cell types). Biol. Chem. 383:585-590.
    • (2002) Biol. Chem. , vol.383 , pp. 585-590
    • Yodoi, J.1    Nakamura, H.2    Masutani, H.3
  • 85
    • 0037150435 scopus 로고    scopus 로고
    • TRAF1: Lord without a RING
    • Zapata, J. M., and J. C. Reed. 2002. TRAF1: lord without a RING. Sci. STKE 2002:PE27.
    • (2002) Sci. STKE , vol.2002
    • Zapata, J.M.1    Reed, J.C.2
  • 86
    • 0029785485 scopus 로고    scopus 로고
    • Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2
    • Zhu, S., A. Y. Sobolev, and R. C. Wek. 1996. Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2. J. Biol. Chem. 271:24989-24994.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24989-24994
    • Zhu, S.1    Sobolev, A.Y.2    Wek, R.C.3
  • 87
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen, H. 2002. Papillomaviruses and cancer: from basic studies to clinical application. Nat. Rev. Cancer 2:342-350.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1


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