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Volumn 88, Issue 6, 2006, Pages 637-643

RNAi in mice: a promising approach to decipher gene functions in vivo

Author keywords

Cre loxP; Fgfr2; Knockdown; Mice; RNAi

Indexed keywords

CRE RECOMBINASE; DOUBLE STRANDED RNA; RNA; RNA DIRECTED DNA POLYMERASE; SMALL INTERFERING RNA;

EID: 33746130403     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2005.11.010     Document Type: Short Survey
Times cited : (23)

References (77)
  • 2
    • 0036642255 scopus 로고    scopus 로고
    • Knockout mice: simple solutions to the problems of genetic background and flanking genes
    • Wolfer D.P., Crusio W.E., and Lipp H.P. Knockout mice: simple solutions to the problems of genetic background and flanking genes. Trends Neurosci. 25 (2002) 336-340
    • (2002) Trends Neurosci. , vol.25 , pp. 336-340
    • Wolfer, D.P.1    Crusio, W.E.2    Lipp, H.P.3
  • 3
    • 84988046619 scopus 로고    scopus 로고
    • An interview with⋯Mario Capecchi. Interview by Magdalena Skipper
    • Capecchi M. An interview with⋯Mario Capecchi. Interview by Magdalena Skipper. Nat. Rev. Genet. 6 (2005) 434
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 434
    • Capecchi, M.1
  • 4
    • 19544371373 scopus 로고    scopus 로고
    • Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century
    • Capecchi M.R. Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat. Rev. Genet. 6 (2005) 507-512
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 507-512
    • Capecchi, M.R.1
  • 5
    • 4344715395 scopus 로고    scopus 로고
    • Generation and analysis of Brca1 conditional knockout mice
    • Deng C.X., and Xu X. Generation and analysis of Brca1 conditional knockout mice. Methods Mol. Biol. 280 (2004) 185-200
    • (2004) Methods Mol. Biol. , vol.280 , pp. 185-200
    • Deng, C.X.1    Xu, X.2
  • 7
    • 21344472766 scopus 로고    scopus 로고
    • RNA interference: a novel and physiologic mechanism of gene silencing with great therapeutic potential
    • Calderon A.J., and Lavergne J.A. RNA interference: a novel and physiologic mechanism of gene silencing with great therapeutic potential. P. R. Health Sci. J. 24 (2005) 27-33
    • (2005) P. R. Health Sci. J. , vol.24 , pp. 27-33
    • Calderon, A.J.1    Lavergne, J.A.2
  • 8
    • 20444410828 scopus 로고    scopus 로고
    • RNA interference libraries prove their worth in hunt for tumor suppressor genes
    • Downward J. RNA interference libraries prove their worth in hunt for tumor suppressor genes. Cell 121 (2005) 813-815
    • (2005) Cell , vol.121 , pp. 813-815
    • Downward, J.1
  • 10
    • 20044366920 scopus 로고    scopus 로고
    • Cell microarrays and RNA interference chip away at gene function
    • Wheeler D.B., Carpenter A.E., and Sabatini D.M. Cell microarrays and RNA interference chip away at gene function. Nat. Genet. 37 Suppl (2005) S25-S30
    • (2005) Nat. Genet. , vol.37 , Issue.SUPPL
    • Wheeler, D.B.1    Carpenter, A.E.2    Sabatini, D.M.3
  • 11
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S., and Kemphues K.J. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81 (1995) 611-620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 12
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., and Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 (1998) 806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 14
    • 16644398282 scopus 로고    scopus 로고
    • RNA interference: the molecular immune system
    • Bagasra O., and Prilliman K.R. RNA interference: the molecular immune system. J Mol Histol 35 (2004) 545-553
    • (2004) J Mol Histol , vol.35 , pp. 545-553
    • Bagasra, O.1    Prilliman, K.R.2
  • 15
    • 23044437498 scopus 로고    scopus 로고
    • RNA meets chromatin
    • Bernstein E., and Allis C.D. RNA meets chromatin. Genes Dev. 19 (2005) 1635-1655
    • (2005) Genes Dev. , vol.19 , pp. 1635-1655
    • Bernstein, E.1    Allis, C.D.2
  • 16
    • 18044364215 scopus 로고    scopus 로고
    • Molecular mechanisms of RNAi: implications for development and disease
    • Rao M., and Sockanathan S. Molecular mechanisms of RNAi: implications for development and disease. Birth Defects Res C Embryo Today 75 (2005) 28-42
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 28-42
    • Rao, M.1    Sockanathan, S.2
  • 17
    • 26944497194 scopus 로고    scopus 로고
    • Structural domains in RNAi
    • Collins R.E., and Cheng X. Structural domains in RNAi. FEBS Lett. 579 (2005) 5841-5849
    • (2005) FEBS Lett. , vol.579 , pp. 5841-5849
    • Collins, R.E.1    Cheng, X.2
  • 19
    • 0034716924 scopus 로고    scopus 로고
    • An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
    • Dalmay T., Hamilton A., Rudd S., Angell S., and Baulcombe D.C. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell 101 (2000) 543-553
    • (2000) Cell , vol.101 , pp. 543-553
    • Dalmay, T.1    Hamilton, A.2    Rudd, S.3    Angell, S.4    Baulcombe, D.C.5
  • 20
    • 0035798399 scopus 로고    scopus 로고
    • RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs
    • Lipardi C., Wei Q., and Paterson B.M. RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs. Cell 107 (2001) 297-307
    • (2001) Cell , vol.107 , pp. 297-307
    • Lipardi, C.1    Wei, Q.2    Paterson, B.M.3
  • 21
    • 0037322606 scopus 로고    scopus 로고
    • RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase
    • Stein P., Svoboda P., Anger M., and Schultz R.M. RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase. RNA 9 (2003) 187-192
    • (2003) RNA , vol.9 , pp. 187-192
    • Stein, P.1    Svoboda, P.2    Anger, M.3    Schultz, R.M.4
  • 22
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., and Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 (2001) 494-498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 23
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir S.M., Martinez J., Patkaniowska A., Lendeckel W., and Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20 (2001) 6877-6888
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 24
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir S.M., Lendeckel W., and Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15 (2001) 188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 25
    • 0038419800 scopus 로고    scopus 로고
    • Induction of an interferon response by RNAi vectors in mammalian cells
    • Bridge A.J., Pebernard S., Ducraux A., Nicoulaz A.L., and Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34 (2003) 263-264
    • (2003) Nat. Genet. , vol.34 , pp. 263-264
    • Bridge, A.J.1    Pebernard, S.2    Ducraux, A.3    Nicoulaz, A.L.4    Iggo, R.5
  • 32
    • 18144453718 scopus 로고    scopus 로고
    • Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system
    • Coumoul X., Li W., Wang R.H., and Deng C. Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system. Nucleic Acids Res. 32 (2004) e85
    • (2004) Nucleic Acids Res. , vol.32
    • Coumoul, X.1    Li, W.2    Wang, R.H.3    Deng, C.4
  • 33
    • 26444461266 scopus 로고    scopus 로고
    • Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference
    • Coumoul X., Shukla V., Li C., Wang R.H., and Deng C.X. Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference. Nucleic Acids Res. 33 (2005) e102
    • (2005) Nucleic Acids Res. , vol.33
    • Coumoul, X.1    Shukla, V.2    Li, C.3    Wang, R.H.4    Deng, C.X.5
  • 34
    • 0037134623 scopus 로고    scopus 로고
    • RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells
    • Hohjoh H. RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells. FEBS Lett. 521 (2002) 195-199
    • (2002) FEBS Lett. , vol.521 , pp. 195-199
    • Hohjoh, H.1
  • 35
    • 1642491747 scopus 로고    scopus 로고
    • Enhancement of RNAi activity by improved siRNA duplexes
    • Hohjoh H. Enhancement of RNAi activity by improved siRNA duplexes. FEBS Lett. 557 (2004) 193-198
    • (2004) FEBS Lett. , vol.557 , pp. 193-198
    • Hohjoh, H.1
  • 36
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu J.Y., DeRuiter S.L., and Turner D.L. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 99 (2002) 6047-6052
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 37
    • 0038725897 scopus 로고    scopus 로고
    • Genome-wide RNAi screening in Caenorhabditis elegans
    • Kamath R.S., and Ahringer J. Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30 (2003) 313-321
    • (2003) Methods , vol.30 , pp. 313-321
    • Kamath, R.S.1    Ahringer, J.2
  • 39
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F., and Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2 (2000) 70-75
    • (2000) Nat. Cell Biol. , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 40
    • 0038708339 scopus 로고    scopus 로고
    • Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
    • Kunath T., Gish G., Lickert H., Jones N., Pawson T., and Rossant J. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 21 (2003) 559-561
    • (2003) Nat. Biotechnol. , vol.21 , pp. 559-561
    • Kunath, T.1    Gish, G.2    Lickert, H.3    Jones, N.4    Pawson, T.5    Rossant, J.6
  • 41
    • 21244490466 scopus 로고    scopus 로고
    • Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos
    • Lickert H., Cox B., Wehrle C., Taketo M.M., Kemler R., and Rossant J. Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos. Development 132 (2005) 2599-2609
    • (2005) Development , vol.132 , pp. 2599-2609
    • Lickert, H.1    Cox, B.2    Wehrle, C.3    Taketo, M.M.4    Kemler, R.5    Rossant, J.6
  • 43
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G., Singer O., Ikawa M., and Verma I.M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100 (2003) 1844-1848
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 45
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu F., Song Y., and Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. 6 (1999) 1258-1266
    • (1999) Gene Ther. , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 46
    • 33645937646 scopus 로고    scopus 로고
    • The mechanism of naked DNA uptake and expression
    • Wolff J.A., and Budker V. The mechanism of naked DNA uptake and expression. Adv. Genet. 54 (2005) 3-20
    • (2005) Adv. Genet. , vol.54 , pp. 3-20
    • Wolff, J.A.1    Budker, V.2
  • 47
    • 0033166561 scopus 로고    scopus 로고
    • High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
    • Zhang G., Budker V., and Wolff J.A. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum. Gene Ther. 10 (1999) 1735-1737
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1735-1737
    • Zhang, G.1    Budker, V.2    Wolff, J.A.3
  • 48
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis D.L., Hagstrom J.E., Loomis A.G., Wolff J.A., and Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32 (2002) 107-108
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 49
    • 0036893744 scopus 로고    scopus 로고
    • A story of mice and men
    • McCaffrey A.P., and Kay M.A. A story of mice and men. Gene Ther. 9 (2002) 1563
    • (2002) Gene Ther. , vol.9 , pp. 1563
    • McCaffrey, A.P.1    Kay, M.A.2
  • 53
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • Sorensen D.R., Leirdal M., and Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327 (2003) 761-766
    • (2003) J. Mol. Biol. , vol.327 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 54
    • 0037021437 scopus 로고    scopus 로고
    • Small interfering RNA and gene silencing in transgenic mice and rats
    • Hasuwa H., Kaseda K., Einarsdottir T., and Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532 (2002) 227-230
    • (2002) FEBS Lett. , vol.532 , pp. 227-230
    • Hasuwa, H.1    Kaseda, K.2    Einarsdottir, T.3    Okabe, M.4
  • 55
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz M., and Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77 (2003) 8957-8961
    • (2003) J. Virol. , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 56
    • 0141987925 scopus 로고    scopus 로고
    • Regulatory roles of presenilin-1 and nicastrin in neuronal differentiation during in vitro neurogenesis
    • Sarkar S.N., and Das H.K. Regulatory roles of presenilin-1 and nicastrin in neuronal differentiation during in vitro neurogenesis. J. Neurochem. 87 (2003) 333-343
    • (2003) J. Neurochem. , vol.87 , pp. 333-343
    • Sarkar, S.N.1    Das, H.K.2
  • 58
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi M., and Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20 (2002) 497-500
    • (2002) Nat. Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 59
    • 0042662862 scopus 로고    scopus 로고
    • Establishment of conditional vectors for hairpin siRNA knockdowns
    • Matsukura S., Jones P.A., and Taka D. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res. 31 (2003)) e77
    • (2003) Nucleic Acids Res. , vol.31
    • Matsukura, S.1    Jones, P.A.2    Taka, D.3
  • 60
    • 7244219858 scopus 로고    scopus 로고
    • Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown
    • Chang H.S., Lin C.H., Yu Y.C., and Chen W.C. Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown. Am. J. Pathol. 165 (2004) 1535-1541
    • (2004) Am. J. Pathol. , vol.165 , pp. 1535-1541
    • Chang, H.S.1    Lin, C.H.2    Yu, Y.C.3    Chen, W.C.4
  • 62
    • 0346655234 scopus 로고    scopus 로고
    • Roles of FGF receptors in mammalian development and congenital diseases
    • Coumoul X., and Deng C.X. Roles of FGF receptors in mammalian development and congenital diseases. Birth Defects Res C Embryo Today 69 (2003) 286-304
    • (2003) Birth Defects Res C Embryo Today , vol.69 , pp. 286-304
    • Coumoul, X.1    Deng, C.X.2
  • 64
    • 0031885801 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
    • Xu X., Weinstein M., Li C., Naski M., Cohen R.I., Ornitz D.M., Leder P., and Deng C. Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125 (1998) 753-765
    • (1998) Development , vol.125 , pp. 753-765
    • Xu, X.1    Weinstein, M.2    Li, C.3    Naski, M.4    Cohen, R.I.5    Ornitz, D.M.6    Leder, P.7    Deng, C.8
  • 65
    • 0034754894 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning
    • Li C., Guo H., Xu X., Weinberg W., and Deng C.X. Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev. Dyn. 222 (2001) 471-483
    • (2001) Dev. Dyn. , vol.222 , pp. 471-483
    • Li, C.1    Guo, H.2    Xu, X.3    Weinberg, W.4    Deng, C.X.5
  • 66
    • 0035858870 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body
    • Li X., Chen Y., Scheele S., Arman E., Haffner-Krausz R., Ekblom P., and Lonai P. Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body. J. Cell Biol. 153 (2001) 811-822
    • (2001) J. Cell Biol. , vol.153 , pp. 811-822
    • Li, X.1    Chen, Y.2    Scheele, S.3    Arman, E.4    Haffner-Krausz, R.5    Ekblom, P.6    Lonai, P.7
  • 67
    • 1242340460 scopus 로고    scopus 로고
    • Frontonasal process-specific disruption of AP-2alpha results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects
    • Nelson D.K., and Williams T. Frontonasal process-specific disruption of AP-2alpha results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects. Dev. Biol. 267 (2004) 72-92
    • (2004) Dev. Biol. , vol.267 , pp. 72-92
    • Nelson, D.K.1    Williams, T.2
  • 68
    • 0031700905 scopus 로고    scopus 로고
    • FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
    • Weinstein M., Xu X., Ohyama K., and Deng C.X. FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125 (1998) 3615-3623
    • (1998) Development , vol.125 , pp. 3615-3623
    • Weinstein, M.1    Xu, X.2    Ohyama, K.3    Deng, C.X.4
  • 70
    • 0030726908 scopus 로고    scopus 로고
    • Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals
    • Kioussis D., and Festenstein R. Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals. Curr. Opin. Genet. Dev. 7 (1997) 614-619
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 614-619
    • Kioussis, D.1    Festenstein, R.2
  • 71
    • 0038451470 scopus 로고    scopus 로고
    • Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5′ HS4 insulator element
    • Frazar T.F., Weisbein J.L., Anderson S.M., Cline A.P., Garrett L.J., Felsenfeld G., Gallagher P.G., and Bodine D.M. Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5′ HS4 insulator element. Mol. Cell. Biol. 23 (2003) 4753-4763
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4753-4763
    • Frazar, T.F.1    Weisbein, J.L.2    Anderson, S.M.3    Cline, A.P.4    Garrett, L.J.5    Felsenfeld, G.6    Gallagher, P.G.7    Bodine, D.M.8
  • 72
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21 (1999) 70-71
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 73
    • 4644229437 scopus 로고    scopus 로고
    • The design and exogenous delivery of siRNA for post-transcriptional gene silencing
    • Gilmore I.R., Fox S.P., Hollins A.J., Sohail M., and Akhtar S. The design and exogenous delivery of siRNA for post-transcriptional gene silencing. J. Drug Target. 12 (2004) 315-340
    • (2004) J. Drug Target. , vol.12 , pp. 315-340
    • Gilmore, I.R.1    Fox, S.P.2    Hollins, A.J.3    Sohail, M.4    Akhtar, S.5
  • 74
    • 25644448153 scopus 로고    scopus 로고
    • Mammalian RNAi: a practical guide
    • Sandy P., Ventura A., and Jacks T. Mammalian RNAi: a practical guide. Biotechniques 39 (2005) 215-224
    • (2005) Biotechniques , vol.39 , pp. 215-224
    • Sandy, P.1    Ventura, A.2    Jacks, T.3
  • 77
    • 0141678494 scopus 로고    scopus 로고
    • A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis
    • Chen L., Li D., Li C., Engel A., and Deng C.X. A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis. Bone 33 (2003) 169-178
    • (2003) Bone , vol.33 , pp. 169-178
    • Chen, L.1    Li, D.2    Li, C.3    Engel, A.4    Deng, C.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.