Knockout mice: Simple solutions to the problems of genetic background and flanking genes

Trends in Neurosciences

Volumn 25, Issue 7, 2002, Pages 336-340

  Wolfer, David P ^a   Crusio, Wim E ^b   Lipp, Hans Peter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREEDING METHOD; CHIMERA; CONGENIC STRAIN; DNA FLANKING REGION; DOMINANT INHERITANCE; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC DRIFT; HAPLOTYPE; HETEROSIS; HOMOLOGOUS RECOMBINATION; INBRED STRAIN; KNOCKOUT GENE; KNOCKOUT MOUSE; MOLECULAR MIMICRY; MOUSE STRAIN; MUTANT; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; RECESSIVE INHERITANCE; REVIEW; STEM CELL;

3' FLANKING REGION; 5' FLANKING REGION; ANIMALS; BREEDING; GENE TARGETING; GENOTYPE; MICE; MICE, KNOCKOUT; MUTATION; PHENOTYPE;

EID: 0036642255     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(02)02192-6     Document Type: Review

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