Final results of phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group

Chest

Volumn 117, Issue 2, 2000, Pages 358-364

  Sause, William ^a   Kolesar, Patricia ^b   Taylor IV, Samuel ^c   Johnson, David ^d   Livingston, Robert ^e   Komaki, Ritsuko ^f   Emami, Bahman ^g   Curran Jr , Walter ^h   Byhardt, Roger ⁱ   Rashid Dar, A ^j   Turrisi III, Andrew ^k  

^a LDS HOSPITAL   (United States)

^b RTOG Headquarters   (United States)

^c ADVOCATE ILLINOIS MASONIC MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g HINES VA HOSPITAL   (United States)

^h THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

ⁱ CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^j LONDON REGIONAL CANCER PROGRAM   (Canada)

^k MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

more..

Author keywords

Chemotherapy; Hyperfractionated radiation; Lung cancer; Phase III trial; Radiation

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; VINBLASTINE;

ADVANCED CANCER; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LUNG NON SMALL CELL CANCER; MALE; MULTIMODALITY CANCER THERAPY; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION DOSE;

EID: 0033993435     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.117.2.358     Document Type: Article

References (25)

1. 1 Landis S, Murray T, Bolden S, et al. Cancer statistics by race and ethnicity. CA Cancer J Clin 1998; 48:6-29
2. 2 Perez CA, Stanley K, Rubin P, et al. A prospective randomized study of various irradiation doses and fractionation scheduled in the treatment of inoperable non-oat-cell carcinoma of the lung: preliminary report by the Radiation Therapy Oncology Group. Cancer 1980; 45:2744-2753
3. 3 LeChevalier T, Arriagada R, Quoix E, et al. Radiotherapy alone versus combined chemotherapy and radiotherapy in nonresectable non-small cell lung cancer: first analysis of a randomized trial in 353 patients. J Natl Cancer Inst 1991; 83:417-423
4. 4 Schaake-Koning C, van den Bogaert W, Dalesio O, et al. Effects of concomitant cisplatin and radiotherapy on inoperable non-small cell lung cancer. N Engl J Med 1992; 326: 524-530
5. 5 Morton RF, Jett JR, McGinnis WL, et al. Thoracic radiation therapy alone compared with combined chemoradiotherapy for locally unresectable non-small cell lung cancer: a randomized, phase III trial. Ann Intern Med 1991; 115:681-686
6. 6 Mattson K, Holsti LR, Holsti P, et al. Inoperable non-small cell lung cancer: radiation with or without chemotherapy. Eur J Cancer Clin Oncol 1988; 24:477-482
7. 7 Scott C, Sause WT, Byhardt SC, et al. Recursive partitioning analysis of 1,592 patients on four RTOG studies in non-small cell lung cancer [abstract]. Proc Am Soc Clin Oncol 1993; 12:336
8. 8 Dillman RO, Herndon J, Seagren S, et al. Improved survival in stage III non-small center lung cancer: seven-year follow-up of Cancer and Leukemia Group B (CALGB) 8433 Trial. J Natl Cancer Inst 1996; 88:1210-1215
9. 9 Cullen MH, Billingham LJ, Woodroffe CM, et al. Mitomycin, ifosfamide and cisplatin (MIC) in non-small cell lung cancer (NSCLC): 1. Results of a randomized trial in patients with localized inoperable disease. Lung Cancer 1997; 18(suppl): 1-5
10. 10 Trovo MG, Minatel E, Veronesi A, et al. Combined radiotherapy and chemotherapy versus radiotherapy alone in locally advanced epidermoid bronchogenic carcinoma: a randomized study. Cancer 1990; 65:400-404
11. 11 White JE, Chen T, Reed R, et al. Limited squamous cell carcinoma of the lung: a Southwest Oncology Group randomized study of radiation with or without doxorubicin chemotherapy and with or without levamisole immunotherapy. Cancer Treat Rep 1982; 66:1113-1120
12. 12 Sause WT, Scott C, Taylor S, et al. Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588: preliminary results of a phase III trial in regionally advanced, unresectable non-small cell lung cancer. J Natl Cancer Inst 1995; 87:198-205
13. 13 Cox JD, Azarnia N, Byhardt RW, et al. A randomized phase I/II trial of hyperfractionated radiation therapy with total doses of 60.0 Gy to 79.2 Gy: possible survival benefit with greater than or equal to 69.6 Gy in favorable patients with Radiation Therapy Oncology Group stage III non-small cell lung carcinoma; report of Radiation Therapy Oncology Group 83.11. J Clin Oncol 1990; 8:1543-1555
14. 14 Bauer M, Birch R, Pajak RT. Prognostic factors in cancer of the lung. In: Cox JD, ed. Syllabus: a categorical course in radiation therapy; lung cancer. Oak Brook, IL: Radiological Society of North America, 1985; 87-111
15. 15 Mountain CF. A new international staging system for lung cancer. Chest 1986; 89 (suppl):225S-233S
16. 16 Yesner R, Seydel GH, Asbell SO, et al. Biopsies of non-small cell lung cancer: central review in cooperative studies of the Radiation Therapy Oncology Group. Mod Pathol 1991; 4:432-435
17. 17 Gaynor JJ, Feuer EJ, Tan CC. On the use of cause-specific failure and conditional failure probabilities: examples from clinic oncology data. J Am Stat Assoc 1993; 88:400-409
18. 18 Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53:457-481
19. 19 Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22:719-748
20. 20 Gehan EA. A generalized Wilcoxon test for comparing arbitrarily single-censored samples. Biometrika 1965; 52:203-223
21. 21 Non-small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials. BMJ 1995; 311:899-909
22. 22 Southwest Oncology Group. SWOG self-exam finds elderly under-accrued in clinical trials. Oncology News Int 1998; (Newsletter)
23. 23 Dillman RO, Seagren SL, Propert KJ, et al. A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small cell lung cancer (see comment citations in MEDLINE). N Engl J Med; 1990; 323:940-945
24. 24 Komakai R, Scott CB, Sause WT, et al. Induction cisplatin/vinblastine and irradiation vs irradiation in unresectable squamous cell lung cancer: Mure patterns by cell type in RTOG 88-08/ECOG 4588. Int J Radiat Oncol Biol Phys 1997; 39:537-544
25. 25 Saunders MI, Dische S, Barrett A,. et al. Randomized multicenter trials of CHART vs conventional radiotherapy in head and neck and non-small cell lung cancer: an interim report. Br J Cancer 1996; 73:1455-1462