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Volumn 11, Issue 2 I, 2005, Pages 795-805

The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PACLITAXEL;

EID: 19944427144     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (228)

References (42)
  • 2
    • 0032858243 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer
    • Furuse K, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 1999;17:2692-9.
    • (1999) J Clin Oncol , vol.17 , pp. 2692-2699
    • Furuse, K.1    Fukuoka, M.2    Kawahara, M.3
  • 3
    • 0003313092 scopus 로고    scopus 로고
    • Phase III comparison of sequential vs. concurrent chemoradiation for patients with unresected stage III non-small cell lung cancer (NSCLC): Initial report of radiation therapy oncology group (RTOG) 9410
    • Curran WJ, Scott C, Langer C, et al. Phase III comparison of sequential vs. concurrent chemoradiation for patients with unresected stage III non-small cell lung cancer (NSCLC): initial report of radiation therapy oncology group (RTOG) 9410 [abstract]. Proc Am Soc Clin Oncol 2000;19:484A.
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Curran, W.J.1    Scott, C.2    Langer, C.3
  • 4
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3
  • 5
    • 0030980781 scopus 로고    scopus 로고
    • Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor α is frequent in resectable non-small cell lung cancer but does not predict tumor progression
    • Rusch V, Klimstra D, Venkatraman E, et al. Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor α is frequent in resectable non-small cell lung cancer but does not predict tumor progression. Clin Cancer Res 1997;3:515-22.
    • (1997) Clin Cancer Res , vol.3 , pp. 515-522
    • Rusch, V.1    Klimstra, D.2    Venkatraman, E.3
  • 6
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-related growth factor and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small cell lung cancers: Amphiregulin and microvessel count are independent prognostic indicators of survival
    • Fontanini G, De Laurentiis M, Vignati S, et al. Evaluation of epidermal growth factor-related growth factor and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small cell lung cancers: amphiregulin and microvessel count are independent prognostic indicators of survival. Clin Cancer Res 1998;4:241-9.
    • (1998) Clin Cancer Res , vol.4 , pp. 241-249
    • Fontanini, G.1    De Laurentiis, M.2    Vignati, S.3
  • 7
    • 0018654080 scopus 로고
    • Epidermal growth factor
    • Carpenter G. Epidermal growth factor. Annual Rev Biochem 1979;48: 193-216.
    • (1979) Annual Rev Biochem , vol.48 , pp. 193-216
    • Carpenter, G.1
  • 8
    • 0034799139 scopus 로고    scopus 로고
    • A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
    • Ciardiello F, Tortora G. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin Cancer Res 2001;7: 2958-70.
    • (2001) Clin Cancer Res , vol.7 , pp. 2958-2970
    • Ciardiello, F.1    Tortora, G.2
  • 9
    • 0036124415 scopus 로고    scopus 로고
    • Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C225 in the treatment of lung and head and neck cancers
    • Herbst R, Langer C. Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers. Semin Oncol 2002;29:27-36.
    • (2002) Semin Oncol , vol.29 , pp. 27-36
    • Herbst, R.1    Langer, C.2
  • 10
    • 0031409362 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
    • Mendelsohn J. Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy. Clin Cancer Res 1997;3: 2703-7.
    • (1997) Clin Cancer Res , vol.3 , pp. 2703-2707
    • Mendelsohn, J.1
  • 11
    • 0034114769 scopus 로고    scopus 로고
    • Blockade of receptors for growth factors: An anticancer therapy - The Fourth Annual Joseph H. Burchenal American Association for Cancer Research Clinical Research Award Lecture
    • Mendelsohn J. Blockade of Receptors for Growth Factors: an Anticancer Therapy-The Fourth Annual Joseph H. Burchenal American Association for Cancer Research Clinical Research Award Lecture. Clin Cancer Res 2000;6:747-53.
    • (2000) Clin Cancer Res , vol.6 , pp. 747-753
    • Mendelsohn, J.1
  • 12
    • 0032815618 scopus 로고    scopus 로고
    • Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
    • Dent P, Reardon DB, Park JS, et al. Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 1999;10:4231-46.
    • (1999) Mol Biol Cell , vol.10 , pp. 4231-4246
    • Dent, P.1    Reardon, D.B.2    Park, J.S.3
  • 13
    • 0032719534 scopus 로고    scopus 로고
    • Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
    • Akimoto T, Hunter NR, Buchmiller L, et al. Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 1999;5:2884-90.
    • (1999) Clin Cancer Res , vol.5 , pp. 2884-2890
    • Akimoto, T.1    Hunter, N.R.2    Buchmiller, L.3
  • 14
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
    • Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000;6:2166-74.
    • (2000) Clin Cancer Res , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2
  • 15
    • 0033748391 scopus 로고    scopus 로고
    • Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide
    • Bianco C, Bianco R, Tortora G, et al. Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide. Clin Cancer Res 2000;6:4343-50.
    • (2000) Clin Cancer Res , vol.6 , pp. 4343-4350
    • Bianco, C.1    Bianco, R.2    Tortora, G.3
  • 16
    • 0027428571 scopus 로고
    • Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-deamminedichloroplatinum on well established A431 cell xenografts
    • Fan Z, Baselga J, Masui H, et al. Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-deamminedichloroplatinum on well established A431 cell xenografts. Cancer Res 1993;53:4637-42.
    • (1993) Cancer Res , vol.53 , pp. 4637-4642
    • Fan, Z.1    Baselga, J.2    Masui, H.3
  • 17
    • 0033966576 scopus 로고    scopus 로고
    • In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
    • Milas L, Mason K, Hunter N, et al. In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res 2000;6:701-8.
    • (2000) Clin Cancer Res , vol.6 , pp. 701-708
    • Milas, L.1    Mason, K.2    Hunter, N.3
  • 18
    • 0033561522 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
    • Huang SM, Bock JM, Harari PM. Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 1999;59:1935-40.
    • (1999) Cancer Res , vol.59 , pp. 1935-1940
    • Huang, S.M.1    Bock, J.M.2    Harari, P.M.3
  • 19
    • 0023895289 scopus 로고
    • Chemosensitivity testing of human lung cancer cell lines using the MTT assay
    • Carmichael J, Mitchell JB, DeGraff WG, et al. Chemosensitivity testing of human lung cancer cell lines using the MTT assay. Br J Cancer 1988;57:540-7.
    • (1988) Br J Cancer , vol.57 , pp. 540-547
    • Carmichael, J.1    Mitchell, J.B.2    DeGraff, W.G.3
  • 20
    • 0000994406 scopus 로고
    • Analysis of combined drug effects: A new look at a very old problem
    • Chou TC, Talalay P. Analysis of combined drug effects: a new look at a very old problem. Trends Pharmacol Sci 1983;4:450-4.
    • (1983) Trends Pharmacol Sci , vol.4 , pp. 450-454
    • Chou, T.C.1    Talalay, P.2
  • 21
    • 0036118262 scopus 로고    scopus 로고
    • Epidermal growth factor receptor family in lung cancer and premalignancy
    • Franklin W, Veve R, Hirsch F, et al. Epidermal growth factor receptor family in lung cancer and premalignancy. Semin Oncol 2002;29:3-14.
    • (2002) Semin Oncol , vol.29 , pp. 3-14
    • Franklin, W.1    Veve, R.2    Hirsch, F.3
  • 22
    • 0025013846 scopus 로고
    • Immunohistochemical evidence of autocrine growth factors in adenocarcinoma of the lung
    • Tateishi M, Ishida T, Mitsudomi T, et al. Immunohistochemical evidence of autocrine growth factors in adenocarcinoma of the lung. Cancer Res 1990;50:7077-80.
    • (1990) Cancer Res , vol.50 , pp. 7077-7080
    • Tateishi, M.1    Ishida, T.2    Mitsudomi, T.3
  • 24
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • Rusch V, Baselga J, Cordon-Cardo C, et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993;53:2379-85.
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3
  • 25
    • 0034777482 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival
    • Brabender J, Danenberg KD, Metzger R, et al. Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival. Clin Cancer Res 2001;7:1850-5.
    • (2001) Clin Cancer Res , vol.7 , pp. 1850-1855
    • Brabender, J.1    Danenberg, K.D.2    Metzger, R.3
  • 26
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small-cell lung carcinoma correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch FR, Varella-Garcia M, Bunn PA Jr, et al. Epidermal growth factor receptor in non-small-cell lung carcinoma correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003;21:3780-98.
    • (2003) J Clin Oncol , vol.21 , pp. 3780-3798
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn Jr., P.A.3
  • 27
    • 0027290650 scopus 로고
    • Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
    • Baselga J, Norton L, Masui H, et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993;85:1327-33.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1327-1333
    • Baselga, J.1    Norton, L.2    Masui, H.3
  • 28
    • 0032904485 scopus 로고    scopus 로고
    • Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225
    • Ciardiello F, Bianco R, Damiano V, et al. Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. Clin Cancer Res 1999;5:909-16.
    • (1999) Clin Cancer Res , vol.5 , pp. 909-916
    • Ciardiello, F.1    Bianco, R.2    Damiano, V.3
  • 29
    • 18844473781 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
    • Bruns CJ, Harbison MT, Davis SW, et al. Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clin Cancer Res 2000;6:1936-48.
    • (2000) Clin Cancer Res , vol.6 , pp. 1936-1948
    • Bruns, C.J.1    Harbison, M.T.2    Davis, S.W.3
  • 30
    • 0034489914 scopus 로고    scopus 로고
    • Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase
    • Sirotnak FM, Zakowski MF, Miller VA, et al. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 2000;6:4885-92.
    • (2000) Clin Cancer Res , vol.6 , pp. 4885-4892
    • Sirotnak, F.M.1    Zakowski, M.F.2    Miller, V.A.3
  • 31
    • 17344382185 scopus 로고    scopus 로고
    • Combined modality therapy of A431 human epidermoid cancer using anti-EGFR antibody C225 and radiation
    • Saleh MH, Raisch KP, Stackhouse MA, et al. Combined modality therapy of A431 human epidermoid cancer using anti-EGFR antibody C225 and radiation. Cancer Biother Radiopharm 1999;14:451-63.
    • (1999) Cancer Biother Radiopharm , vol.14 , pp. 451-463
    • Saleh, M.H.1    Raisch, K.P.2    Stackhouse, M.A.3
  • 32
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003;290:2149-58.
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 33
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
    • Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003;5: 2237-46.
    • (2003) J Clin Oncol , vol.5 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 34
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small cell lung cancer: A phase III trial-INTACT 1
    • Giaccone G, Herbst RS, Manegold C, et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol 2004;22:777-84.
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 35
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non-small cell lung cancer: A phase III clinical trial - INTACT 2
    • Herbst RS, Giaccone G, Schiller JH, et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small cell lung cancer: a phase III clinical trial- INTACT 2. J Clin Oncol 2004;22:785-94.
    • (2004) J Clin Oncol , vol.22 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 36
    • 0037499945 scopus 로고    scopus 로고
    • Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: Limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways
    • Janmaat ML, Kruyt FA, Rodriguez JA, et al. Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways. Clin Cancer Res 2003;9:2316-26.
    • (2003) Clin Cancer Res , vol.9 , pp. 2316-2326
    • Janmaat, M.L.1    Kruyt, F.A.2    Rodriguez, J.A.3
  • 37
    • 0036094196 scopus 로고    scopus 로고
    • Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
    • Soria JC, Lee HY, Lee JI, et al. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. Clin Cancer Res 2002;8:1178-84.
    • (2002) Clin Cancer Res , vol.8 , pp. 1178-1184
    • Soria, J.C.1    Lee, H.Y.2    Lee, J.I.3
  • 38
    • 0037111274 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer xenografts with Erbirux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
    • Buchsbaum DJ, Bonner JA, Grizzle WE, et al. Treatment of pancreatic cancer xenografts with Erbirux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. Int J Radiat Oncol Biol Phys 2002;54:1180-93.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 1180-1193
    • Buchsbaum, D.J.1    Bonner, J.A.2    Grizzle, W.E.3
  • 39
    • 0035479052 scopus 로고    scopus 로고
    • C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability
    • OCT 1
    • Nasu S, Ang KK, Fan Z, et al. C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability. Int J Radiat Oncol Biol Phys 2001 Oct 1;51:474-7.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 474-477
    • Nasu, S.1    Ang, K.K.2    Fan, Z.3
  • 40
    • 33751580192 scopus 로고    scopus 로고
    • A phase II study of cetuximab, an epidermal growth factor receptor (EGFR) blocking antibody, in combination with docetaxel in chemotherapy refractory/resistant patients with advanced non-small cell lung cancer: Final report
    • Kim ES, Mauer AM, Tran HT, et al. A phase II study of cetuximab, an epidermal growth factor receptor (EGFR) blocking antibody, in combination with docetaxel in chemotherapy refractory/resistant patients with advanced non-small cell lung cancer: Final report [Abstract 2581]. Proc Am Soc Clin Oncol 2003;22:642.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 642
    • Kim, E.S.1    Mauer, A.M.2    Tran, H.T.3
  • 41
    • 0038140033 scopus 로고    scopus 로고
    • Cetuximab (C225) in combination with cisplatin/vinorelbine vs. cisplatin/vinorelbine alone in the first-line treatment of patients (pts) with epidermal growth factor receptor (EGFR) positive advanced non-small-cell lung cancer (NSCLC)
    • Gatzemeier U, Rosell R, Ramlau R. Cetuximab (C225) in combination with cisplatin/vinorelbine vs. cisplatin/vinorelbine alone in the first-line treatment of patients (pts) with epidermal growth factor receptor (EGFR) positive advanced non-small-cell lung cancer (NSCLC) [Abstract 2582]. Proc Am Soc Clin Oncol 2003;22:642.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 642
    • Gatzemeier, U.1    Rosell, R.2    Ramlau, R.3
  • 42
    • 0035398021 scopus 로고    scopus 로고
    • Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
    • Robert F, Ezekiel MP, Spencer SA, et al. Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J Clin Oncol 2001;19:3234-43.
    • (2001) J Clin Oncol , vol.19 , pp. 3234-3243
    • Robert, F.1    Ezekiel, M.P.2    Spencer, S.A.3


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